Similar dynamics of intraapheresis autologous CD34+ recruitment and collection efficiency in patients undergoing mobilization with or without plerixafor

Academic Article

Abstract

  • Background Compared with growth factor (G) alone, the combination of G with plerixafor (G + P) increases peripheral blood CD34+ count (PB-CD34+) and improves CD34+ collection yield (yCD34+) in multiple myeloma and lymphoma patients undergoing autologous hematopoietic progenitor cell (AHPC) mobilization. It is unknown whether the improved yCD34+ with G + P results entirely from expansion of PB-CD34+ or also from increased intraapheresis CD34+ recruitment and collection efficiency.
  • Published In

  • Transfusion  Journal
  • Digital Object Identifier (doi)

    Author List

  • Schade H; Chhabra S; Kang Y; Stuart RK; Edwards KH; Kramer C; Butcher C; Littleton A; Schneider M; Budisavljevic MN
  • Start Page

  • 3131
  • End Page

  • 3137
  • Volume

  • 54
  • Issue

  • 12