The murine glutamine:fructose-6-phosphate amidotransferase-encoding cDNA sequence

Academic Article


  • Glutamine:fructose-6-phosphate amidotransferase (GFAT) is the rate-limiting enzyme in hexosamine synthesis and has been implicated in the control of growth factor gene expression. We cloned a mouse cDNA which is 91% homologous to the human sequence. The deduced amino-acid sequence shows 98.6% identity to human GFAT. The cDNA is derived from a 7-kb mRNA in the mouse, while there are multiple-sized human mRNAs. © 1994.
  • Authors

    Published In

  • Gene  Journal
  • Digital Object Identifier (doi)

    Author List

  • Sayeski PP; Paterson AJ; Kudlow JE
  • Start Page

  • 289
  • End Page

  • 290
  • Volume

  • 140
  • Issue

  • 2