Selected Publications

Academic Article

Year Title Altmetric
2021 Puma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosisCell Death and Disease.  12. 2021
2021 Generation and application of a versatile CRISPR toolkit for mammalian cell engineering 2021
2020 Synthetic immunomodulation with a CRISPR super-repressor in vivoNature Cell Biology.  22:1143-1154. 2020
2019 Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interferenceBiotechnology and Bioengineering.  116:1813-1819. 2019
2018 An enhanced CRISPR repressor for targeted mammalian gene regulationNature methods.  15:611-616. 2018
2018 Enhanced Bacterial Immunity and Mammalian Genome Editing via RNA-Polymerase-Mediated Dislodging of Cas9 from Double-Strand DNA BreaksMolecular Cell.  71:42-55.e8. 2018
2018 Characterization of coding/noncoding variants for SHROOM3 in patients with CKDJournal of the American Society of Nephrology.  29:1525-1535. 2018
2017 SgRNA Scorer 2.0: A Species-Independent Model to Predict CRISPR/Cas9 Activity 2017
2016 Genome-wide association studies identify genetic loci associated with Albuminuria in diabetesDiabetes.  65:803-817. 2016
2015 Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity 2015
2014 Refined mapping of a hypertension susceptibility locus on rat chromosome 12Hypertension.  64:883-890. 2014
2010 Renal medullary MicroRNAs in dahl salt-sensitive rats: MiR-29b regulates several collagens and related genesHypertension.  55:974-982. 2010
CRISPR guide RNA cloning for mammalian systemsJournal of Visualized Experiments.  2018.

Education And Training

  • Doctor of Philosophy in Physiology, Medical College of Wisconsin 2015
  • Full Name

  • Nan Cher Yeo