Robin Lester

Robin Lester
Professor

Scientist (C), Comprehensive Neuroscience Center , General Clinical Research Center
Scientist (C), Civitan International Research Center , Academic Joint Departments
Professor (P), Neurobiology , Academic Joint Departments
Professor (S), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments

Selected Publications

Academic Article

Year	Title	Altmetric
2011	Cognitive mechanisms underlying relapse to nicotine. Reviews in the Neurosciences. 22:467-470. 2011
2011	Short- and long-lasting consequences of in vivo nicotine treatment on hippocampal excitability 2011
2009	Cellular events in nicotine addiction. Seminars in Cell and Developmental Biology. 20:418-431. 2009
2009	Demonstration of functional α4-containing nicotinic receptors in the medial habenula. Neuropharmacology. 56:247-253. 2009
2007	Ca²⁺ flux and signaling implications by nicotinic acetylcholine receptors in rat medial habenula. Journal of Neurophysiology. 97:83-92. 2007
2007	Regulation of nicotinic acetylcholine receptor desensitization by Ca ²⁺. Journal of Neurophysiology. 97:93-101. 2007
2006	Simvastatin enhances learning and memory independent of amyloid load in mice. Annals of Neurology. 60:729-739. 2006
2005	Rapid upregulation of α7 nicotinic acetylcholine receptors by tyrosine dephosphorylation 2005
2004	Activation and desensitization of heteromeric neuronal nicotinic receptors: Implications for non-synaptic transmission. Bioorganic and Medicinal Chemistry Letters. 14:1897-1900. 2004
2003	Interactions of atropine with heterologously expressed and native α3 subunit-containing nicotinic acetylcholine receptors. British Journal of Pharmacology. 138:801-810. 2003
2002	Desensitization of neuronal nicotinic receptors. Developmental Neurobiology. 53:457-478. 2002
2002	Prolonged stimulation of presynaptic nicotinic acetylcholine receptors in the rat interpeduncular nucleus has differential effects on transmitter release. International Journal of Developmental Neuroscience. 20:247-258. 2002
2000	Regulation of the sensitivity of acetylcholine receptors to nicotine in rat habenula neurons 2000
2000	Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons. Neuropharmacology. 39:2591-2603. 2000
2000	Symposium overview: Mechanism of action of nicotine on neuronal acetylcholine receptors, from molecule to behavior. Toxicological Sciences. 57:193-202. 2000
2000	Temporal appearance of the presynaptic cytomatrix protein Bassoon during synaptogenesis. Molecular and Cellular Neuroscience. 15:417-428. 2000
1999	Upregulation of surface α4β2 nicotinic receptors is initiated by receptor desensitization after chronic exposure to nicotine 1999
1999	α3β4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons. Neuropharmacology. 38:769-783. 1999
1999	Alpha3beta4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons.. Neuropharmacology. 38:769-783. 1999
1999	Desensitization of nicotinic receptors in the central nervous system. Annals of the New York Academy of Sciences. 868:620-623. 1999
1999	Regulation of α4β2 nicotinic receptor desensitization by calcium and protein kinase C. Molecular Pharmacology. 55:432-443. 1999
1997	Influence of subunit composition on desensitization of neuronal acetylcholine receptors at low concentrations of nicotine 1997
1995	Acetylcholine receptor desensitization induced by nicotine in rat medial habenula neurons. Journal of Neurophysiology. 74:195-206. 1995
1994	Time-dependent changes in central nicotinic acetylcholine channel kinetics in excised patches. Neuropharmacology. 33:27-34. 1994
1993	Interactions between the glycine and glutamate binding sites of the NMDA receptor 1993
1992	NMDA channel behavior depends on agonist affinity 1992
1992	Synaptic excitation mediated by glutamate-gated ion channels. Current Opinion in Neurobiology. 2:270-274. 1992
1992	The time course of glutamate in the synaptic cleft. Science. 258:1498-1501. 1992
1990	Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature. 346:565-567. 1990
1990	Quisqualate receptor-mediated depression of calcium currents in hippocampal neurons. Neuron. 4:741-749. 1990
1989	Excitatory amino acid receptors in the vertebrate central nervous system. Pharmacological Reviews. 41:143-210. 1989
1989	Interaction of 6-cyano-7-nitroquinoxaline-2,3-dione with the N-methyl-D-aspartate receptor-associated glycine binding site. Molecular Pharmacology. 35:565-570. 1989
1989	Learning by handshake? [5]. Nature. 339:588. 1989
1989	Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation. Nature. 338:500-503. 1989
1988	Ketamine blocks an NMDA receptor-mediated component of synaptic transmission in rat hippocampus in a voltage-dependent manner. Neuroscience Letters. 92:213-217. 1988
1988	Frequency‐dependent N‐methyl‐D‐aspartate receptor‐mediated synaptic transmission in rat hippocampus. 1988
1988	Synaptic activation of N‐methyl‐D‐aspartate receptors in the Schaffer collateral‐commissural pathway of rat hippocampus. 1988
1986	Frequency-dependent involvement of NMDA receptors in the hippocampus: A novel synaptic mechanism. Nature. 322:265-268. 1986
1985	Intracellular demonstration of an N-methyl-d-aspartate receptor mediated component of synaptic transmission in the rat hippocampus. Neuroscience Letters. 60:19-23. 1985

Book

Year	Title	Altmetric
2014	Nicotinic Receptors 2014

Chapter

Year	Title	Altmetric
2014	On the discovery of the nicotinic acetylcholine receptor channel. 1-16. 2014
2012	Defining the role of the hippocampus in nicotine addiction. 53-78. 2012
2012	The time course of NMDA receptor-mediated synaptic currents 2012

Education And Training

Doctor of Philosophy in Pharmacology, 1987

Full Name

Robin Lester

Robin Lester
Professor

Publications

Selected Publications

Academic Article

Book

Chapter

Research

Principal Investigator On

Investigator On

Teaching

Teaching Activities

Background

Education And Training

Contact

Full Name

Robin Lester Professor

E-mail

Phone

Visualizations

Publications

Selected Publications

Academic Article

Book

Chapter

Research

Principal Investigator On

Investigator On

Teaching

Teaching Activities

Background

Education And Training

Contact

Full Name

Robin Lester
Professor