| Year |
Title |
Altmetric |
| 2022
|
Thrombospondin-1 Signaling Through the Calreticulin/LDL Receptor Related Protein 1 Axis: Functions and Possible Roles in Glaucoma.
Frontiers in Cell and Developmental Biology.
10.
2022
|
|
| 2022
|
Runx2 Deficiency in Osteoblasts Promotes Myeloma Resistance to Bortezomib by Increasing TSP-1–Dependent TGFβ1 Activation and Suppressing Immunity in Bone Marrow.
Molecular Cancer Therapeutics.
21:347-358.
2022
|
|
| 2020
|
Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy.
Matrix Biology Plus.
8.
2020
|
|
| 2020
|
Identification of Inhibitors of Thrombospondin 1 Activation of TGF-β.
ACS Medicinal Chemistry Letters.
11:1130-1136.
2020
|
|
| 2020
|
The 2019 FASEB Science Research Conference on Matricellular Proteins in Inflammation and Tissue Remodeling, July 14–19, 2019, Lisbon, Portugal
2020
|
|
| 2019
|
Denervation-induced skeletal muscle fibrosis is mediated by CTGF/CCN2 independently of TGF-β.
Matrix Biology.
82:20-37.
2019
|
|
| 2019
|
Thrombospondin 1 and Its Diverse Roles as a Regulator of Extracellular Matrix in Fibrotic Disease
2019
|
|
| 2019
|
Multiscale simulation of the interaction of calreticulin-thrombospondin-1 complex with a model membrane microdomain.
Journal of Biomolecular Structure and Dynamics.
37:811-822.
2019
|
|
| 2018
|
Pericytes elicit resistance to vemurafenib and sorafenib therapy in thyroid carcinoma via the TSP-1/TGFB1 axis.
Clinical Cancer Research.
24:6078-6097.
2018
|
|
| 2018
|
Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease.
Matrix Biology.
68-69:28-43.
2018
|
|
| 2018
|
The role of the endoplasmic reticulum protein calreticulin in mediating TGF-β-stimulated extracellular matrix production in fibrotic disease.
Journal of Cell Communication and Signaling.
12:289-299.
2018
|
|
| 2018
|
Thrombospondins: Purification of human platelet thrombospondin-1.
Methods in Cell Biology.
143:347-369.
2018
|
|
| 2016
|
Calreticulin Regulates Neointima Formation and Collagen Deposition following Carotid Artery Ligation.
Journal of Vascular Research.
52:306-320.
2016
|
|
| 2016
|
Inhibition of transforming growth factor-β activation diminishes tumor progression and osteolytic bone disease in mouse models of multiple myeloma.
American Journal of Pathology.
186:678-690.
2016
|
|
| 2015
|
High-magnitude and/or high-frequency mechanical strain promotes peripapillary scleral myofibroblast differentiation
2015
|
|
| 2015
|
The Thrombospondin1-TGF-β Pathway and Glaucoma.
Journal of Ocular Pharmacology and Therapeutics.
31:371-375.
2015
|
|
| 2014
|
Molecular insight into the effect of lipid bilayer environments on thrombospondin-1 and calreticulin interactions.
Biochemistry.
53:6309-6322.
2014
|
|
| 2014
|
Hyperglycemic arterial disturbed flow niche as an in vitro model of atherosclerosis.
Analytical Chemistry.
86:10948-10954.
2014
|
|
| 2014
|
Revisiting the matricellular concept.
Matrix Biology.
37:1-14.
2014
|
|
| 2014
|
The role of matricellular proteins in glaucoma.
Matrix Biology.
37:174-182.
2014
|
|
| 2013
|
Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production.
Journal of Biological Chemistry.
288:14584-14598.
2013
|
|
| 2013
|
CD36, but not G2A, modulates efferocytosis, infl ammation, and fibrosis following bleomycin-induced lung injury.
Journal of Lipid Research.
54:1114-1123.
2013
|
|
| 2012
|
Thrombospondin-1 inhibits osteogenic differentiation of human mesenchymal stem cells through latent TGF-β activation.
Biochemical and Biophysical Research Communications.
422:488-493.
2012
|
|
| 2012
|
Thrombospondin1 in tissue repair and fibrosis: TGF-β-dependent and independent mechanisms.
Matrix Biology.
31:178-186.
2012
|
|
| 2012
|
Thrombospondins in physiology and disease: New tricks for old dogs.
Matrix Biology.
31:152-154.
2012
|
|
| 2012
|
Thrombospondin-1 in early flow-related remodeling of mesenteric arteries from young normotensive and spontaneously hypertensive rats.
Open Cardiovascular Medicine Journal.
6:50-59.
2012
|
|
| 2011
|
Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation
2011
|
|
| 2011
|
Molecular and structural insight into the role of key residues of thrombospondin-1 and calreticulin in thrombospondin-1-calreticulin binding.
Biochemistry.
50:566-573.
2011
|
|
| 2011
|
Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy.
American Journal of Pathology.
178:2573-2586.
2011
|
|
| 2011
|
TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine.
Gastroenterology.
140:242-253.
2011
|
|
| 2010
|
Human cytomegalovirus induces TGF-β1 activation in renal tubular epithelial cells after epithelial-to- mesenchymal transition.
PLoS Pathogens.
6.
2010
|
|
| 2010
|
Modulation of mammary cancer cell migration by 15-deoxy-Δ 12,14-prostaglandin J2: Implications for anti-metastatic therapy.
Biochemical Journal.
430:69-78.
2010
|
|
| 2010
|
Thy-1-integrin αvβ5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-β1 activation and myofibroblast differentiation.
Journal of Biological Chemistry.
285:22382-22393.
2010
|
|
| 2010
|
Stainless steel ions stimulate increased thrombospondin-1-dependent tgf-beta activation by vascular smooth muscle cells: Implications for in-stent restenosis.
Journal of Vascular Research.
47:309-322.
2010
|
|
| 2010
|
Structural insight into the role of thrombospondin-1 binding to calreticulin in calreticulin-induced focal adhesion disassembly.
Biochemistry.
49:3685-3694.
2010
|
|
| 2010
|
Glucose downregulation of PKG-I protein mediates increased thrombospondin1-dependent TGF-β activity in vascular smooth muscle cells
2010
|
|
| 2010
|
Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix.
Journal of Biological Chemistry.
285:7067-7078.
2010
|
|
| 2010
|
Calreticulin: Non-endoplasmic reticulum functions in physiology and disease
2010
|
|
| 2010
|
The calreticulin-binding sequence of thrombospondin 1 regulates collagen expression and organization during tissue remodeling.
American Journal of Pathology.
177:1710-1724.
2010
|
|
| 2009
|
β1 integrin cytoplasmic variants differentially regulate expression of the antiangiogenic extracellular matrix protein thrombospondin 1.
Cancer Research.
69:5374-5382.
2009
|
|
| 2009
|
Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cγ and increase epithelial cell migration through indirect epidermal growth factor receptor activation.
Journal of Biological Chemistry.
284:6389-6402.
2009
|
|
| 2009
|
Latent transforming growth factor-β-binding protein-4 regulates transforming growth factor-β1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin.
American Journal of Pathology.
174:21-33.
2009
|
|
| 2009
|
The counteradhesive proteins, thrombospondin 1 and SPARC/osteonectin, open the tyrosine phosphorylation-responsive paracellular pathway in pulmonary vascular endothelia.
Microvascular Research.
77:13-20.
2009
|
|
| 2008
|
Thrombospondin 1 binding to calreticulin-LRP1 signals resistance to anoikis
2008
|
|
| 2008
|
LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies.
Physiological Reviews.
88:887-918.
2008
|
|
| 2008
|
Transforming growth factor-β signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung
2008
|
|
| 2008
|
Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions.
Pediatric Research.
63:26-32.
2008
|
|
| 2008
|
The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation
2008
|
|
| 2007
|
Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration.
Circulation Research.
100:654-661.
2007
|
|
| 2007
|
A thrombospondin-1 antagonist of transforming growth factor-β activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II.
American Journal of Pathology.
171:777-789.
2007
|
|
| 2007
|
Endothelin-1 Mediates Hypoxia-Induced Increases in Vascular Collagen in the Newborn Mouse Lung.
Pediatric Research.
61:559-564.
2007
|
|
| 2006
|
Thy-1, via its GPI anchor, modulates Src family kinase and focal adhesion kinase phosphorylation and subcellular localization, and fibroblast migration, in response to thrombospondin-1/hep I.
Experimental Cell Research.
312:3752-3767.
2006
|
|
| 2006
|
Function-blocking antithrombospondin-1 monoclonal antibodies.
Journal of Thrombosis and Haemostasis.
4:459-468.
2006
|
|
| 2006
|
Thrombospondin 1 mediates angiotensin II induction of TGF-β activation by cardiac and renal cells under both high and low glucose conditions.
Biochemical and Biophysical Research Communications.
339:633-641.
2006
|
|
| 2005
|
Glutathione restores collagen degradation in TGF-β-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen
2005
|
|
| 2005
|
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte.
Cell.
123:321-334.
2005
|
|
| 2005
|
Endothelin-A receptor blockade prevents and partially reverses neonatal hypoxic pulmonary vascular remodeling.
Pediatric Research.
57:631-636.
2005
|
|
| 2005
|
Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics
2005
|
|
| 2004
|
Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly.
Journal of Biological Chemistry.
279:48983-48992.
2004
|
|
| 2004
|
The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-β complex.
Journal of Biological Chemistry.
279:47633-47642.
2004
|
|
| 2004
|
Molecular interactions that confer latency to transforming growth factor-β.
Journal of Biological Chemistry.
279:38032-38039.
2004
|
|
| 2004
|
Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-β activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2.
Journal of Biological Chemistry.
279:34311-34322.
2004
|
|
| 2004
|
Elevated expression of TGF-β1 in head and neck cancer-associated fibroblasts.
Molecular Carcinogenesis.
40:116-121.
2004
|
|
| 2004
|
The N-terminus of thrombospondin: The domain stands apart
2004
|
|
| 2004
|
Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation.
Journal of Biological Chemistry.
279:23510-23516.
2004
|
|
| 2004
|
Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity.
Experimental Cell Research.
295:488-496.
2004
|
|
| 2004
|
Intercellular Adhesion Molecule-1 (ICAM-1) Regulates Endothelial Cell Motility through a Nitric Oxide-dependent Pathway.
Journal of Biological Chemistry.
279:19230-19238.
2004
|
|
| 2004
|
Regulation of endothelial cell function by FAK and Pyk2.
Frontiers in Bioscience-Landmark.
9:1254-1266.
2004
|
|
| 2004
|
Thrombospondin-1 is a major activator of TGF-β in fibrotic renal disease in the rat in vivo.
Kidney International.
65:459-468.
2004
|
|
| 2004
|
Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-β in response to fibrogenic stimuli.
American Journal of Pathology.
165:659-669.
2004
|
|
| 2003
|
Expression of constitutively active cGMP-dependent protein kinase prevents glucose stimulation of thrombospondin 1 expression and TGF-β activity.
Diabetes.
52:2144-2150.
2003
|
|
| 2003
|
Thrombospondin signaling through the calreticulin/LDL receptor-related protein co-complex stimulates random and directed cell migration.
Journal of Cell Science.
116:2917-2927.
2003
|
|
| 2003
|
Amino acids induce indicators of response to injury in glomerular mesangial cells
2003
|
|
| 2003
|
Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly
2003
|
|
| 2003
|
Cellular response to hypoxia involves signaling via Smad proteins.
Blood.
101:2253-2260.
2003
|
|
| 2002
|
The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.
Journal of Biological Chemistry.
277:37219-37228.
2002
|
|
| 2002
|
Thrombospondin stimulates focal adhesion disassembly through Gi- and phosphoinositide 3-kinase-dependent ERK activation.
Journal of Biological Chemistry.
277:20453-20460.
2002
|
|
| 2002
|
Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-β activation in mesangial cells.
Journal of Biological Chemistry.
277:9880-9888.
2002
|
|
| 2001
|
Actions of the soy phytoestrogen genistein in models of human chronic disease: potential involvement of transforming growth factor beta..
Biochemical Society Transactions.
29:216-222.
2001
|
|
| 2001
|
Tamoxifen and estrogen effects on TGF-β formation: Role of thrombospondin-1, αvβ3, and integrin-associated protein.
Biochemical and Biophysical Research Communications.
284:11-14.
2001
|
|
| 2001
|
The de-adhesive activity of matricellular proteins: Is intermediate cell adhesion an adaptive state?.
Journal of Clinical Investigation.
107:785-790.
2001
|
|
| 2000
|
Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin.
Journal of Biological Chemistry.
275:36358-36368.
2000
|
|
| 2000
|
Restructuring of focal adhesion plaques by PI 3-kinase: Regulation by PtdIns (3,4,5)-P3 binding to α-actinin
2000
|
|
| 2000
|
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis.
Free Radical Biology and Medicine.
28:1780-1794.
2000
|
|
| 2000
|
Activation of latent TGF-β by thrombospondin-1: Mechanisms and physiology.
Cytokine and Growth Factor Reviews.
11:59-69.
2000
|
|
| 2000
|
A CD36 synthetic peptide inhibits bleomycin-induced pulmonary inflammation and connective tissue synthesis in the rat.
American Journal of Respiratory Cell and Molecular Biology.
23:204-212.
2000
|
|
| 2000
|
Glucose stimulation of transforming growth factor-β bioactivity in mesangial cells is mediated by thrombospondin-1.
American Journal of Pathology.
157:1353-1363.
2000
|
|
| 1999
|
Retinoic acid alters the mechanism of attachment of malignant astrocytoma and neuroblastoma cells to thrombospondin-1.
Experimental Cell Research.
249:86-101.
1999
|
|
| 1999
|
The activation sequence of thrombospondin-1 interacts with the latency- associated peptide to regulate activation of latent transforming growth factor-β.
Journal of Biological Chemistry.
274:13586-13593.
1999
|
|
| 1999
|
Activation of rat alveolar macrophage-derived latent transforming growth factor β-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36.
American Journal of Pathology.
155:841-851.
1999
|
|
| 1999
|
Thrombospondin peptides are potent inhibitors of mesangial and glomerular endothelial cell proliferation in vitro and in vivo.
Kidney International.
55:2236-2249.
1999
|
|
| 1999
|
Thrombospondin-1 induces tyrosine phosphorylation of adherens junction proteins and regulates an endothelial paracellular pathway.
Molecular Biology of the Cell.
10:1537-1551.
1999
|
|
| 1998
|
Signaling of de-adhesion in cellular regulation and motility.
Microscopy Research and Technique.
43:420-432.
1998
|
|
| 1998
|
Thrombospondin-1 is a major activator of TGF-β1 in vivo.
Cell.
93:1159-1170.
1998
|
|
| 1998
|
EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCγ signaling pathway.
Journal of Cell Science.
111:615-624.
1998
|
|
| 1998
|
Cyclic GMP-dependent protein kinase inhibits osteopontin and thrombospondin production in rat aortic smooth muscle cells.
Circulation Research.
82:139-146.
1998
|
|
| 1998
|
Thrombospondin signaling of focal adhesion disassembly requires activation of phosphoinositide 3-kinase.
Journal of Biological Chemistry.
273:1755-1763.
1998
|
|
| 1997
|
EGF decreases fraction of FAC (focal adhesion complex) positive NR6 mouse febroblasts
1997
|
|
| 1996
|
In vitro AL-ahyloid formation is associated with low TGF-B activity
1996
|
|
| 1996
|
Cyclic GMP-dependent protein kinase is required for thrombospondin and tenascin mediated focal adhesion disassembly.
Journal of Cell Science.
109:2499-2508.
1996
|
|
| 1996
|
A role for gelsolin in actuating epidermal growth factor receptor- mediated cell motility
1996
|
|
| 1996
|
Mitogenesis, cell migration, and loss of focal adhesions induced by tenascin-C interacting with its cell surface receptor, annexin II.
Molecular Biology of the Cell.
7:883-892.
1996
|
|
| 1995
|
Anti-adhesive Proteins of the Extracellular Matrix: Thrombospondin, Tenascin, and SPARC.
Trends in glycoscience and glycotechnology : TIGG.
7:89-100.
1995
|
|
| 1995
|
Heparin-binding vitronectin up-regulates latent TGF-β production by bovine aortic endothelial cells.
Journal of Cell Science.
108:1553-1561.
1995
|
|
| 1995
|
Pathogenesis of glomerulosclerosis in light chain deposition disease: Role for transforming growth factor-β.
American Journal of Pathology.
147:375-385.
1995
|
|
| 1995
|
Regulation of transforming growth factor-β activation by discrete sequences of thrombospondin 1.
Journal of Biological Chemistry.
270:7304-7310.
1995
|
|
| 1995
|
SPARC mediates focal adhesion disassembly in endothelial cells through a follistatin‐like region and the Ca2+‐binding EF‐hand.
Journal of Cellular Biochemistry.
57:341-350.
1995
|
|
| 1994
|
The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-β.
Journal of Biological Chemistry.
269:26783-26788.
1994
|
|
| 1994
|
Thrombospondin binds and activates the small and large forms of latent transforming growth factor-β in a chemically defined system.
Journal of Biological Chemistry.
269:26775-26782.
1994
|
|
| 1994
|
Identification and Possible Localization of cGMP-Dependent Protein Kinase in Bovine Aortic Endothelial Cells.
Biochemical and Biophysical Research Communications.
201:531-537.
1994
|
|
| 1993
|
Erratum: (Journal of Cell Biology (August 1993) 122:4 (923-932))
1993
|
|
| 1993
|
Heparin-binding peptides from thrombospondins 1 and 2 contain focal adhesion-labilizing activity.
Journal of Biological Chemistry.
268:26784-26789.
1993
|
|
| 1993
|
Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism
1993
|
|
| 1992
|
Erratum: (The Journal of Cell Biology, Murphy-Ullrich et al., Vol. 115, No. 4, 1127-1136)
1992
|
|
| 1992
|
Regulation of cell substrate adhesion: Effects of small galactosaminoglycan-containing proteoglycans
1992
|
|
| 1992
|
Transforming growth factor-β complexes with thrombospondin.
Molecular Biology of the Cell.
3:181-188.
1992
|
|
| 1992
|
Urokinase binding to laminin‐nidogen: Structural requirements and interactions with heparin
1992
|
|
| 1991
|
Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin.
1991
|
|
| 1991
|
A different approach to determining platelet thrombospondin receptors
1991
|
|
| 1991
|
Focal adhesion integrity is downregulated by the alternatively spliced domain of human tenascin
1991
|
|
| 1989
|
Thrombospondin modulates focal adhesions in endothelial cells
1989
|
|
| 1988
|
Altered metabolism of thrombospondin by Chinese hamster ovary cells defective in glycosaminoglycan synthesis.
Journal of Biological Chemistry.
263:6400-6406.
1988
|
|
| 1987
|
Interactions of thrombospondin with endothelial cells: receptor-mediated binding and degradation.
1987
|
|
| 1987
|
Interactions of thrombospondin with cells in culture: rapid degradation of both soluble and matrix thrombospondin..
Seminars in vascular medicine.
13:343-351.
1987
|
|
| 1987
|
Interactions of thrombospondin with endothelial cells: receptor-mediated binding and degradation.
1987
|
|
| 1986
|
Serologic and pathologic studies of mice immunized with homologous fibronectin.
American Journal of Pathology.
125:182-190.
1986
|
|
| 1985
|
Localization of thrombospondin in clots formed in situ.
Blood.
66:1098-1104.
1985
|
|
| 1984
|
Detection of autoantibodies and glomerular injury in rabbits immunized with denatured human fibronectin monomer.
American Journal of Pathology.
117:1-11.
1984
|
|
| 1984
|
Immune-mediated injury to basement membranes in mice immunized with murine laminin.
Clinical Immunology.
31:33-43.
1984
|
|
| 1984
|
Localization of thrombospondin in clots formed in situ
1984
|
|
| 1983
|
The effect of the dimeric and multimeric forms of fibronectin on the adhesion and growth of primary glomerular cells.
Experimental Cell Research.
145:265-276.
1983
|
|
| 1982
|
Glomerular and vascular injury in mice following immunization with heterologous and autologous fibronectin.
Virchows Archiv B Cell Pathology Zell-Pathologie.
39:305-321.
1982
|
|
| 1981
|
Morphologic and immunofluorescence studies of the effect of fibroblast growth factor on the culture of guinea pig glomerular cell strains.
American Journal of Pathology.
103:129-136.
1981
|
|
| 1981
|
Studies on the localization of the glycoprotein GP-2 within the renal glomerulus in vivo and in cultured kidney cell strains in vitro
1981
|
|
| 1981
|
The effect of fetal calf serum on the biology of cultured primary glomerular cells
1981
|
|
| 1981
|
The growth of primary glomerular cells as a confluent monolayer in a chemically defined serum-free medium. Specific requirements for prostaglandins and extracellular matrix molecules.
American Journal of Pathology.
104:181-188.
1981
|
|
| 1980
|
Growth and maintenance of glomerular cells under defined conditions.
American Journal of Pathology.
101:195-203.
1980
|
|
