Basic Science: Up until 1994, I was engaged in basic science research efforts directed to understanding the pathogenesis of pulmonary mycotic infections. First to describe a murine model of conidial induced pulmonary blastomycosis, which demonstrated that macrophages are essential cells in the initial host-parasite interaction.
Clinical Microbiology/Applied: Due to the nature of clinical microbiology, my areas of investigation and publication are diverse and include mycology, bacteriology, mycobacteriology, and antimicrobial susceptibility testing. Most studies have involved the assessment of methods for providing more rapid or accurate test results to physicians. My special area of interest is in Mycology, specifically in the in vitro antifungal susceptibility, diagnostic methods, and molecular typing.
Medical Informatics: The application of methodologies to facilitate the collection, management, and evaluation of information produced in medicine. These efforts lead to the system that is the basis of MedMined, Inc. and acquired by Cardinal Health in 2000.