Mike Chen

Mike Chen
Professor

Professor (S), Pediatric - Academic General Pediatrics , Pediatrics
Professor (P), Surgery - Pediatric , Surgery

Overview

Dr. Mike Chen attended University of Texas and UT Health Sciences Center in Houston. He trained in general surgery at University of Florida. He completed fellowships in Transplantation and then Pediatric Surgery. He was on faculty at UMDNJ-Camden from 1996-2000. He joined the faculty at UF in Gainesville from 2000-2009. He was recruited to UAB in September, 2009. He is the Director of the Division of Pediatric Surgery and Surgeon-in-Chief of the Children’s Hospital. His focus is on providing the best clinical care possible for infants and children and to inspire young surgeons to do the same. He has a strong interest in education and mentorship.

Dr. Chen’s clinical interests include all aspects of pediatric surgery with particular focus in anorectal malformation, Hirschsprung’s disease, bowel management, congenital anomalies, thoracic defects and minimal invasive surgery. He is also engaged in a prospective study on adolescent bariatric surgery.

Selected Publications

Academic Article

Year	Title	Altmetric
2022	Who manages burn injuries in children? A program director survey evaluating burn training during pediatric surgery fellowship. Journal of Pediatric Surgery. 57:127-129. 2022
2021	Perforated Appendicitis during a Pandemic: The Downstream Effect of COVID-19 in Children. Journal of Surgical Research. 268:263-266. 2021
2021	Trending diversity: Reviewing four-decades of graduating fellows and the current leadership in pediatric surgery. Journal of Pediatric Surgery. 56:1294-1298. 2021
2021	The diminishing experience in pediatric surgery for general surgery residents in the United States. Journal of Pediatric Surgery. 56:1219-1221. 2021
2021	The Disturbing Findings of Pediatric Firearm Injuries From the National Trauma Data Bank: 2010-2016. Journal of Surgical Research. 259:224-229. 2021
2020	Esophageal Foreign Body Management in Children: Can It Wait?. Journal of Laparoendoscopic and Advanced Surgical Techniques. 30:1286-1288. 2020
2020	Bariatric Surgery in Adolescents. Current treatment options in pediatrics. 6:140-154. 2020
2020	Weight Loss and Health Status 5 Years After Adjustable Gastric Banding in Adolescents. Obesity Surgery. 30:2388-2394. 2020
2020	Nutritional Risks in Adolescents After Bariatric Surgery. Clinical Gastroenterology and Hepatology. 18:1070-1081.e5. 2020
2019	Five-year outcomes of gastric bypass in adolescents as compared with adults. New England Journal of Medicine. 380:2136-2145. 2019
2019	Firearm injuries and children: Position statement of the American pediatric surgical association. Pediatrics. 144. 2019
2018	Systemic Thrombolysis of an Occlusive Aortic Thrombus in a Neonate on Extracorporeal Membrane Oxygenation. 2018
2018	Systemic Thrombolysis of an Occlusive Aortic Thrombus in a Neonate on Extracorporeal Membrane Oxygenation. 2018
2018	Systemic thrombolysis of an occlusive aortic thrombus in a neonate on extracorporeal membrane oxygenation 2018
2018	Cardiovascular risk factors after adolescent bariatric surgery. Pediatrics. 141. 2018
2017	Changes in Dietary Intake and Eating Behavior in Adolescents After Bariatric Surgery: an Ancillary Study to the Teen-LABS Consortium. Obesity Surgery. 27:3082-3091. 2017
2017	Open versus laparoscopic approach to gastric fundoplication in children with cardiac risk factors. Journal of Surgical Research. 220:52-58. 2017
2017	Utilization of the NSQIP-Pediatric Database in Development and Validation of a New Predictive Model of Pediatric Postoperative Wound Complications. Journal of the American College of Surgeons. 224:532-544. 2017
2017	Survey on Robot-Assisted Surgical Techniques Utilization in US Pediatric Surgery Fellowships. Journal of Laparoendoscopic and Advanced Surgical Techniques. 27:186-190. 2017
2016	Outcome assessment of renal replacement therapy in neonates. Journal of Surgical Research. 204:34-38. 2016
2016	Risk factors for stricture formation after esophageal atresia repair. Journal of Laparoendoscopic and Advanced Surgical Techniques. 26:393-398. 2016
2016	Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. New England Journal of Medicine. 374:113-123. 2016
2016	Defining the role of a pediatric surgery fellowship program director: Results of a national cross-sectional survey 2016
2015	The effort and outcomes of the Pediatric Surgery match process: Are we interviewing too many?. Journal of Pediatric Surgery. 50:1954-1957. 2015
2015	Musculoskeletal pain, self-reported physical function, and quality of life in the Teen-Longitudinal Assessment of Bariatric Surgery (Teen-LABS) cohort. JAMA Pediatrics. 169:552-559. 2015
2015	Cardiovascular risk factors in severely obese adolescents the teen longitudinal assessment of bariatric surgery (Teen-LABS) study. JAMA Pediatrics. 169:438-444. 2015
2015	Routine utilization of Single-Incision Pediatric Endosurgery (SIPES): A 5-year institutional experience. Journal of Laparoendoscopic and Advanced Surgical Techniques. 25:252-255. 2015
2015	Single-incision pediatric endosurgery (SIPES) splenectomy: what dictates the need for additional ports? 2015
2014	Role of laparoscopy in the prevention and in the treatment of adhesions. Seminars in Pediatric Surgery. 23:353-356. 2014
2014	Extraction of esophageal foreign bodies in children: Rigid versus flexible endoscopy. Pediatric Surgery International. 30:417-422. 2014
2014	Utility of immature granulocyte percentage in pediatric appendicitis. Journal of Surgical Research. 190:230-234. 2014
2013	Laparoscopic cholecystectomy for biliary dyskinesia in children: Frequency increasing. Journal of Pediatric Surgery. 48:1716-1721. 2013
2013	Single incision pediatric endosurgery (SIPES) appendectomy - Is obesity a contraindication?. Journal of Pediatric Surgery. 48:1399-1404. 2013
2013	Single-incision pediatric endosurgery for ovarian pathology. Journal of Laparoendoscopic and Advanced Surgical Techniques. 23:291-296. 2013
2012	Angiodysplasia (vascular malformations) of the colon presenting as an acute abdomen. Journal of Pediatric Surgery. 47. 2012
2012	Feasibility of single-incision pediatric endosurgery for treatment of appendicitis in 415 children. Journal of Laparoendoscopic and Advanced Surgical Techniques. 22:604-608. 2012
2012	Laparoscopic surgery in children with congenital heart disease. Journal of Pediatric Surgery. 47:1084-1088. 2012
2010	American Pediatric Surgical Association New Technology Committee review on video-assisted thoracoscopic surgery for childhood cancer. Journal of Pediatric Surgery. 45:2227-2233. 2010
2010	Outcomes of treatment of childhood achalasia. Journal of Pediatric Surgery. 45:1173-1177. 2010
2009	Position paper on laparoscopic antireflux operations in infants and children for gastroesophageal reflux disease. Journal of Pediatric Surgery. 44:1034-1040. 2009
2009	Equestrian injuries in children. Journal of Pediatric Surgery. 44:148-150. 2009
2009	Position paper on video-assisted thoracoscopic surgery as treatment of pediatric empyema. Journal of Pediatric Surgery. 44:289-293. 2009
2008	Pediatric basal cell carcinoma: case reports and literature review. Journal of Pediatric Surgery. 43:2277-2280. 2008
2008	A case of dual thoracoabdominal impalement in vehicular trauma 2008
2008	Traumatic aortic injuries in the pediatric population. Journal of Pediatric Surgery. 43:1077-1081. 2008
2008	Impaired wound healing in an acute diabetic pig model and the effects of local hyperglycemia. Wound Repair and Regeneration. 16:288-293. 2008
2008	Ashes, embers, and coals: Significant sources of burn-related morbidity in children. Journal of Burn Care and Research. 29:109-113. 2008
2008	Mesenteric lipoblastoma: a rare location in children. Journal of Pediatric Surgery. 43:e5. 2008
2007	The use of Seprafilm® in pediatric surgical patients 2007
2007	Salvaging the "lost peritoneum" after ventriculoatrial shunt failures. Child's Nervous System. 23:483-486. 2007
2007	Systemic and Localized Reversible Regulation of Transgene Expression by Tetracycline with tetR-Mediated Transcription Repression Switch. Journal of Surgical Research. 138:267-274. 2007
2006	Differential response of neuroblastoma cells to TRAIL is independent of PI3K/AKT. Journal of Pediatric Surgery. 41:1072-1080. 2006
2006	Current Practice in Pediatric Surgery. Surgical Clinics of North America. 86. 2006
2006	One-year outcomes of Roux-en-Y gastric bypass for morbidly obese adolescents: A multicenter study from the Pediatric Bariatric Study Group. Journal of Pediatric Surgery. 41:137-143. 2006
2005	VEGF-mediated survivin expression in neuroblastoma cells. Journal of Surgical Research. 127:21-28. 2005
2004	Administration of prenatal betamethasone suppresses the adrenal-hypophyseal axis in newborns with congenital diaphragmatic hernia. Journal of Pediatric Surgery. 39:1176-1182. 2004
2004	Artificial rearing of mouse pups: Development of a mouse pup in a cup model. Pediatric Research. 56:250-255. 2004
2004	Expression of VEGF receptors in cocultured neuroblastoma cells. Journal of Surgical Research. 119:56-65. 2004
2004	Extracorporeal membrane oxygenation combined with endovascular embolization for management of neonatal high-output cardiac failure secondary to intracranial arteriovenous fistula: Case report. Journal of Neurosurgery. 100:197-200. 2004
2004	Animal models for intestinal tissue engineering. Clinical materials. 25:1675-1681. 2004
2003	Neuroblastoma, apoptosis, and growth factors 2003
2003	Twenty years of progress in congenital diaphragmatic hernia at the University of Florida 2003
2003	Expanded application of extracorporeal membrane oxygenation in a pediatric surgery practice.. Annals of Surgery. 237:766-772. 2003
2003	Differential expression of Bcl-2 and Bax may enhance neuroblastoma survival. Journal of Pediatric Surgery. 38:486-491. 2003
2003	VEGF receptors are differentially expressed by neuroblastoma cells in culture. Journal of Pediatric Surgery. 38:514-521. 2003
2002	Small watercraft injuries in children 2002
2002	Caspase 3 expression is altered in a coculture model of neuroblastoma. Journal of Surgical Research. 106:323-327. 2002
2002	Insulin-like growth factor-I protects neuroblastoma against starvation-induced apoptosis and is associated with increased Bcl-2 expression. Journal of Pediatric Surgery. 37:472-476. 2002
2002	VEGF upregulates BCL-2 expression and is associated with decreased apoptosis in neuroblastoma cells. Journal of Pediatric Surgery. 37:467-471. 2002
2001	Age and growth factors in porcine full-thickness wound healing. Wound Repair and Regeneration. 9:371-377. 2001
2001	Gastrointestinal foreign bodies 2001
2001	Small bowel tissue engineering using small intestinal submucosa as a scaffold. Journal of Surgical Research. 99:352-358. 2001
2001	VEGF is upregulated in a neuroblastoma and hepatocyte coculture model. Journal of Surgical Research. 97:34-40. 2001
2000	Neuroblastoma and hepatocyte coculture conditioned media alter apoptosis. Journal of Surgical Research. 90:113-118. 2000
2000	Free fluid on abdominal computed tomography scan after blunt trauma does not mandate exploratory laparotomy in children. Journal of Pediatric Surgery. 35:990-993. 2000
1999	Fas-mediated induction of hepatocyte apoptosis in a neuroblastoma and hepatocyte coculture model. Journal of Surgical Research. 84:82-87. 1999
1999	Analysis of the costs of surgery for Hirschsprung's disease: One-stage laparoscopic pull-through versus two-stage Duhamel procedure. Clinical Pediatrics. 38:593-596. 1999
1999	The effect of leukocyte infiltration on apoptosis in an in vitro thermal injury bioartificial living skin equivalent model. Journal of Burn Care and Research. 20:374-376. 1999
1998	Induction of apoptosis in a neuroblastoma and hepatocyte coculture model. Journal of Surgical Research. 78:123-130. 1998
1997	Infradiaphragmatic extralobar pulmonary sequestration masquerading as an intra-abdominal, suprarenal mass. Pediatric Surgery International. 12:529-531. 1997
1997	Initial experience with laparoscopic-assisted pull-through for Hirschsprung's disease. Journal of Laparoendoscopic and Advanced Surgical Techniques. 1:91-94. 1997
1997	Laparoscopic approach for enteral nutrition in pediatric oncology patients. Journal of Laparoendoscopic and Advanced Surgical Techniques. 1:87-90. 1997
1997	Laparoscopic common duct exploration in a child with recurrent pancreatitis due to a primary fungus ball in the terminal common bile duct. Journal of Laparoendoscopic and Advanced Surgical Techniques. 7:63-67. 1997
1997	Laparoscopic fundoplication in children: A superior technique. Journal of Laparoendoscopic and Advanced Surgical Techniques. 1:71-76. 1997
1997	Perinatal management of enteric duplication cysts of the tongue. American Journal of Perinatology. 14:161-163. 1997
1997	Pilot assessment of interval laparoscopic appendectomy for treatment of perforated appendicitis in children. Journal of Laparoendoscopic and Advanced Surgical Techniques. 1:127-130. 1997
1997	The role of laparoscopic lymph node sampling in children. Journal of Laparoendoscopic and Advanced Surgical Techniques. 1:33-38. 1997
1996	Complications of minimal-access surgery in children. Journal of Pediatric Surgery. 31:1161-1165. 1996
1996	Laparoscopic evaluation and treatment of intestinal malrotation in infants 1996
1996	Tracheal hamartoma: Report of a child with a neck mass. Journal of Pediatric Surgery. 31:1584-1585. 1996
1995	The Use of Minimal Access Surgery in Pediatric Trauma: A Preliminary Report. Journal of laparoendoscopic surgery. 5:295-301. 1995
1994	Liver transplantation at the University of Florida.. The Journal of the Florida Medical Association. Florida Medical Association. 81:335-338. 1994
1993	Influence of progressive tumor growth on glutamine metabolism in skeletal muscle and kidney. Annals of Surgery. 217:655-667. 1993
1992	Adaptive regulation in skeletal muscle glutamine metabolism in endotoxin-treated rats. Journal of Trauma and Acute Care Surgery. 32:600-606. 1992
1992	Cytokine regulation of intestinal glutamine utilization 1992
1992	Mechanisms of accelerated hepatic glutamine efflux in the tumour-bearing rat. Surgical Oncology. 1:173-182. 1992
1991	Glutamine metabolism in cancer: Alterations in inter-organ flux and nutritional strategies. Rivista Italiana di Nutrizione Parenterale ed Enterale. 9:65-71. 1991
1991	The gut: a key organ following injury and infection. Rivista Italiana di Nutrizione Parenterale ed Enterale. 9:7-14. 1991
1991	Endotoxin and Renal Glutamine Metabolism. JAMA Surgery. 126:23-27. 1991
1991	Glutamine metabolism by the endotoxin-injured lung. Journal of Trauma and Acute Care Surgery. 31:1068-1075. 1991
1991	Nutritional support of the surgical oncology patient 1991
1991	The effects of endotoxin on the splanchnic metabolism of glutamine and related substrates. Journal of Trauma and Acute Care Surgery. 31:742-752. 1991
1991	Tumor regulation of hepatic glutamine metabolism. Journal of Parenteral and Enteral Nutrition. 15:159-164. 1991
1990	Tumor glutamine use exceeds intestinal glutamine use in cachectic tumor-bearing rats. Surgical forum. 41:12-14. 1990
1990	Glutamine nutrition: theoretical considerations and therapeutic impact.. Journal of Parenteral and Enteral Nutrition. 14:237S-243S. 1990
1990	Gut glutamine metabolism.. Journal of Parenteral and Enteral Nutrition. 14. 1990

Chapter

Year	Title	Altmetric
2008	Alimentary Tract. 1072-1085. 2008
2008	Short Bowel Syndrome and Intestinal Tissue Engineering. 310-317. 2008

Research Overview

anorectal malformation, Hirschsprung’s disease, bowel management, congenital anomalies, thoracic defects and minimal invasive surgery

Principal Investigator On

Teen Longitudinal Assessment of Bariatric Surgery (Teen LABS) Research Project awarded by ANN & ROBERT H LURIE CHILDREN'S HOSPITAL AT CHICAGO

Teen Longitudinal Assessment of Bariatric Surgery (Teen Labs) awarded by CINCINNATI CHILDREN'S HOSPITAL

Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) awarded by CINCINNATI CHILDREN'S HOSPITAL

Teen Longitudinal Assessment of Bariatric Surgery (Teen-LABS) Research Project awarded by UNIVERSITY OF COLORADO DENVER - NEW

Investigator On

Private Grant awarded by Purdue Pharma LP

Private Grant awarded by Ethicon, Inc.

Timing of Inguinal Hernia Repair in Premature Infants: A Randomized Trial awarded by VANDERBILT UNIVERSITY MEDICAL CENTER ^

Teaching Overview

Dr. Chen was the Program Director for the Pediatric Surgery Fellowship until 2017. He remains committed to the education of medical students, residents, and fellows.