Positions

Overview

  • Dr. Danila is an Associate Professor of Medicine in the Division of Clinical Immunology and Rheumatology at the University of Alabama at Birmingham. Dr. Danila is an implementation scientist and outcome researcher, passionate about improving the quality, effectiveness and processes/delivery of medical care for patients. Her research program focuses on: i) the design and evaluation of culturally-adapted and literacy-appropriate health care interventions that improve outcomes for patients with chronic conditions; ii) the development and implementation of strategies to assist physicians and other health care professionals in engaging in shared decision making and evidence-based clinical practice; iii) understanding how digital health (e.g., telehealth) affects access and quality of rheumatology care in the COVID-19 era.

    Dr. Danila is also interested in the redesign of healthcare delivery processes, decreasing healthcare costs and increasing value-based medical care. She has been actively involved as volunteer for the American College of Rheumatology (ACR). She served on the ACR Insurance Subcommittee (ISC) from 2012-2016. She currently serves as a member of the ACR Committee on Quality of Care.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 Disruptions in Rheumatology Care and the Rise of Telehealth in Response to the COVID-19 Pandemic in a Community Practice–Based NetworkArthritis Care and Research.  73:1153-1161. 2021
    2021 Reducing Immunogenicity of Pegloticase With Concomitant Use of Mycophenolate Mofetil in Patients With Refractory Gout: A Phase II, Randomized, Double-Blind, Placebo-Controlled TrialArthritis and Rheumatology.  73:1523-1532. 2021
    2021 Use of path modeling to inform a clinical decision support application to encourage osteoporosis medication useResearch in Social and Administrative Pharmacy.  17:1267-1275. 2021
    2021 Concerns, healthcare use, and treatment interruptions in patients with common autoimmune rheumatic diseases during the COVID-19 pandemicJournal of Rheumatology.  48:603-607. 2021
    2021 A National Survey of Burnout and Depression Among Fellows Training in Pulmonary and Critical Care Medicine: A Special Report by the Association of Pulmonary and Critical Care Medicine Program DirectorsChest.  159:733-742. 2021
    2021 Antirheumatic Disease Therapies for the Treatment of COVID-19: A Systematic Review and Meta-AnalysisArthritis and Rheumatology.  73:36-47. 2021
    2021 Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activityPLoS ONE.  16. 2021
    2020 Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: Data from the COVID-19 Global Rheumatology Alliance physician-reported registryAnnals of the Rheumatic Diseases.  79:859-866. 2020
    2020 Factors associated with the contemplative stage of readiness to initiate osteoporosis treatmentOsteoporosis International.  31:1283-1290. 2020
    2020 Patient and Rheumatologist Perspectives Regarding Challenges to Achieving Optimal Disease Control in Rheumatoid ArthritisArthritis Care and Research.  72:933-941. 2020
    2020 Design, analysis, power, and sample size calculation for three-phase interrupted time series analysis in evaluation of health policy interventionsJournal of Evaluation in Clinical Practice.  26:826-841. 2020
    2020 Imminent Fracture Risk: A Call to Action for RheumatologistsArthritis Care and Research.  72:741-743. 2020
    2020 A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent.Journal of Clinical and Translational Science.  4:345-353. 2020
    2020 Simulation-based power and sample size calculation for designing interrupted time series analyses of count outcomes in evaluation of health policy interventionsContemporary Clinical Trials Communications.  17. 2020
    2020 Temporal Trends and Factors Associated with Bisphosphonate Discontinuation and RestartJournal of Bone and Mineral Research.  35:478-487. 2020
    2019 Pragmatic Clinical Trials in OsteoporosisCurrent Osteoporosis Reports.  17:521-526. 2019
    2019 Ifnγ induces epigenetic programming of human t-bethi b cells and promotes tlr7/8 and il-21 induced differentiationeLife.  8. 2019
    2019 Genetic influences on susceptibility to rheumatoid arthritis in African-AmericansHuman Molecular Genetics.  28:858-874. 2019
    2019 Uptake and Clinical Utility of Multibiomarker Disease Activity Testing in the United StatesJournal of Rheumatology.  46:237-244. 2019
    2019 Perspectives of Rheumatoid Arthritis Patients on Electronic Communication and Patient-Reported Outcome Data Collection: A Qualitative StudyArthritis Care and Research.  71:80-87. 2019
    2018 Improving drug adherence in osteoporosis: an update on more recent studiesTherapeutic Advances in Musculoskeletal Disease.  10:141-149. 2018
    2018 A Performing Arts Intervention Improves Cognitive Dysfunction in 50 Hospitalized Older AdultsInnovation in Aging.  2. 2018
    2018 Evaluation of a Multimodal, Direct-to-Patient Educational Intervention Targeting Barriers to Osteoporosis Care: A Randomized Clinical TrialJournal of Bone and Mineral Research.  33:763-772. 2018
    2018 Use of Scribes for Documentation Assistance in Rheumatology and Endocrinology Clinics: Impact on Clinic Workflow and Patient and Physician Satisfaction 2018
    2018 Advancing the Science and Practice of Medication AdherenceJournal of General Internal Medicine.  33:216-222. 2018
    2018 Age and fecal microbial strain-specific differences in patients with spondyloarthritis 2018
    2018 CUILESS2016: A clinical corpus applying compositional normalization of text mentionsJournal of Biomedical Semantics.  9. 2018
    2018 Routine use of quantitative disease activity measurements among us rheumatologists: Implications for treat-to-target management strategies in rheumatoid arthritisJournal of Rheumatology.  45:40-44. 2018
    2017 Erratum to: Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot study (Osteoporosis International, (2017), 28, 8, (2495-2503), 10.1007/s00198-017-4073-5)Osteoporosis International.  28:2505. 2017
    2017 Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot studyOsteoporosis International.  1-9. 2017
    2017 Dense genotyping of immune-related regions identifies loci for rheumatoid arthritis risk and damage in African AmericansMolecular Medicine.  23:177-187. 2017
    2016 A multi-modal intervention for Activating Patients at Risk for Osteoporosis (APROPOS): Rationale, design, and uptake of online study intervention materialContemporary Clinical Trials Communications.  4:14-24. 2016
    2016 Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans 2016
    2016 Increased pretreatment serum IFN-β/α ratio predicts non-response to tumour necrosis factor α inhibition in rheumatoid arthritisAnnals of the Rheumatic Diseases.  75:1757-1762. 2016
    2016 Risk of Cardiovascular Outcomes among Psoriasis Patients Treated with Biologics and Other Systemic Agents.J Psoriasis Psoriatic Arthritis.  1:128-137. 2016
    2015 Simple regression for correcting δCt bias in RT-qPCR low-density array data normalizationBMC Genomics.  16. 2015
    2015 Brief report: Expression of interferon-γ receptor genes in peripheral blood mononuclear cells is associated with rheumatoid arthritis and its radiographic severity in african americansArthritis and Rheumatology.  67:1165-1170. 2015
    2015 The role of genetic variants in CRP in radiographic severity in African Americans with early and established rheumatoid arthritisGenes and Immunity.  16:446-451. 2015
    2014 Gene-body mass index interactions are associated with methotrexate toxicity in rheumatoid arthritisAnnals of the Rheumatic Diseases.  73:785-786. 2014
    2014 HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: Hierarchical classification systems, amino acid positions, and residuesArthritis and Rheumatology.  66:3274-3282. 2014
    2013 Editorial: Ethnic-specific genetic analyses in rheumatoid arthritis: Incremental gains but valuable contributions to the big pictureArthritis and Rheumatism.  65:3014-3016. 2013
    2012 Markers of treatment response to methotrexate in rheumatoid arthritis: Where do we stand?International Journal of Rheumatology.  2012. 2012
    2010 Measurement of erythrocyte methotrexate polyglutamate levels: Ready for clinical use in rheumatoid arthritis?Current Rheumatology Reports.  12:342-347. 2010
    2010 Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis 2010
    2010 Radiographic severity of rheumatoid arthritis in African Americans: Results from a multicenter observational studyArthritis Care and Research.  62:624-631. 2010
    2010 Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African AmericansAnnals of the Rheumatic Diseases.  69:625-626. 2010
    2010 Bisphosphonate-associated osteonecrosis of the jaw, with healing after teriparatide: A review of the literature and a case report 2010
    2009 ReplyArthritis Care and Research.  61:1615-1616. 2009
    2009 Recent advances in personalizing rheumatoid arthritis therapy and managementPersonalized Medicine.  6:159-170. 2009
    2009 Annotating the human genome with Disease OntologyBMC Genomics.  10. 2009
    2009 Protective effect of hydroxychloroquine on renal damage in patients with lupus nephritis: LXV, data from a multiethnic US cohortArthritis Care and Research.  61:830-839. 2009
    2009 Renal damage is the most important predictor of mortality within the damage index: Data from LUMINA LXIV, a multiethnic US cohortRheumatology.  48:542-545. 2009
    2009 An african ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in african americansPLoS Genetics.  5. 2009
    2009 Retraction: an African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.PLoS Genetics.  5. 2009
    2009 Understanding personalized medicine in rheumatoid arthritis: A clinician’s guide to the futureTherapeutic Advances in Musculoskeletal Disease.  1:97-105. 2009
    2008 Update on pathogenic mechanisms of systemic necrotizing vasculitisCurrent Rheumatology Reports.  10:430-435. 2008
    2008 Pharmacogenetics of etanercept in rheumatoid arthritisPharmacogenomics.  9:1011-1015. 2008
    2008 Biologics and heart failure in rheumatoid arthritis: Are we any wiser?Current Opinion in Rheumatology.  20:327-333. 2008
    2007 Erratum: Tattoo: Inflicted vasculitis? (Journal of Clinical Rheumatology (2007) 13, (49)) 2007
    2007 Tattoo: inflicted vasculitis? 2007
    2005 Complete coding sequences of the rabbitpox virus genomeJournal of General Virology.  86:2969-2977. 2005
    2003 The genomic sequence of ectromelia virus, the causative agent of mousepoxVirology.  317:165-186. 2003

    Chapter

    Year Title Altmetric
    2018 Rheumatoid arthritis.  183-199. 2018
    2014 Biology of Normal Joint and Evaluation of the Joint Including CLinical, Imaging, and Pathologic Evaluation.  1912-1919. 2014

    Investigator On

  • A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease  awarded by Brigham and Women's Hospital
  • A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of Safety, Tolerability and Efficacy of Pirfenidone in Patients with Rheumatoid Arthritis Interstitial Lung Disease  awarded by Brigham and Women's Hospital
  • ACE Protocol ARA08: Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (StopRA)  awarded by University of California, San Francisco
  • ARA08 - Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (StopRA)  awarded by Emory University
  • Building and InnovatinG: Digital heALTH Technology and Analytics (BIGDATA)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Building and InnovatinG: Digital heAlth Technology and Analytics (BIGDATA) - Data Capture and Integration Core  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Centers of Research Translation (CoRT)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • DNA Sequencing for Newborn Nurseries in the South  awarded by HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY
  • Dissection of the ACPA Response in African-Americans with Rheumatoid Arthritis  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • INvestigations In Gout, Hyperuricemia, and ComorbidiTies (INSIGHT) Center of Research Translation (CORT)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • INvestigations In Gout, Hyperuricemia, and ComorbidiTies (INSIGHT) Center of Research Translation (CORT) - Improving Minority Gout Care and Clinical Research Participation in the Southeast  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Patient-Centered Outcomes Research Translation Center  awarded by Baylor University
  • Private Grant  awarded by UCB, INC.
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group
  • Private Grant  awarded by BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. ^
  • Private Grant  awarded by Janssen
  • Private Grant  awarded by ABBVIE INC
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group
  • Private Grant  awarded by GlaxoSmithKline
  • Private Grant  awarded by Pfizer Pharmaceuticals
  • Private Grant  awarded by HORIZON THERAPEUTICS
  • Private Grant  awarded by HORIZON THERAPEUTICS
  • Private Grant  awarded by BRISTOL MYERS SQUIBB PHARMACEUTICAL COMPANY
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION
  • Private Grant  awarded by ABBVIE INC
  • Private Grant  awarded by ALLENA PHARMACETICALS, INC
  • Strengthening Translational Research in Diverse Enrollment (STRIDE)  awarded by UNIVERSITY OF MASSACHUSETTS (WORCESTER)
  • TLR7 and TLR9-Directed Plasma Cell Formation: Dissecting the Molecular Basis for their Differential Dependence on IFN-Induced Signals  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Multidisciplinary Clinical Research Center (P60)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • UAB Multidisciplinary Clinical Research Center - Project 2: Facilitating Treat-to-Target Using Novel Health Technology with Decision Support  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • UAB Multidisciplinary Clinical Research Center - Project 3  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Education And Training

  • “Carol Davila” University of Medicine and Pharmacy, Internship
  • University of Illinois at Chicago-Advocate Christ Medical Center, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Master of Public Health in Epidemiology, University of Alabama at Birmingham 2014
  • Master of Science in Microbiology, University of Victoria 2003
  • Doctor of Medicine, Carol Davila University of Medicine and Pharmacy of Bucharest 1999
  • Full Name

  • Maria I. Danila