Positions

Overview

  • Dr. Curtis is an Associate Professor of Medicine in the Division of Nephrology. She also serves as the Director of Enrichment for the NIH/NIDDK-funded UAB-UCSD O’Brien Center for Acute Kidney Injury Research. She has graduate faculty status in the Department of Cell, Developmental and Integrative Biology at UAB. She has mentored trainees at the undergraduate, graduate and postdoctoral levels many of whom have continued to pursue academic careers. Dr. Curtis has received mentoring awards including the Department of Medicine Excellence in Mentorship Award and the Graduate Dean's Award for Excellence in Mentorship.

    • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Does G Protein-Coupled Estrogen Receptor 1 Contribute to Cisplatin-Induced Acute Kidney Injury in Male Mice?.  International Journal of Molecular Sciences.  23. 2022
    2022 Does G protein-coupled Estrogen Receptor 1 Contribute to Cisplatin-induced Acute Kidney Injury? 2022
    2022 Does Gender Affirming Hormone Therapy Increase the Risk of Kidney Disease?.  Seminars in Nephrology.  42. 2022
    2022 Kidney Disease Prevalence in Transgender Individuals.  Clinical Journal of the American Society of Nephrology.  17:280-282. 2022
    2021 UAB-UCSD o'brien center for acute kidney injury research 2021
    2021 Renoprotective effect of Stat1 deletion in murine aristolochic acid nephropathy 2021
    2021 Thermoneutral Regulation and Acute Injury: Implications for Acute Kidney Injury 2021
    2020 Protective role of HO-1 against acute kidney injury caused by cutaneous exposure to arsenicals.  Annals of the New York Academy of Sciences.  1480:155-169. 2020
    2019 Immunoglobulin light chains generate proinflammatory and profibrotic kidney injury.  Journal of Clinical Investigation.  129:2792-2806. 2019
    2017 Unique sex- and age-dependent effects in protective pathways in acute kidney injury 2017
    2016 Heme oxygenase-1 gene polymorphisms-toward precision medicine for AKI.  Journal of the American Society of Nephrology.  27:3229-3231. 2016
    2015 Heme oxygenase-1 regulates myeloid cell trafficking in AKI.  Journal of the American Society of Nephrology.  26:2139-2151. 2015
    2015 Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury.  Human Molecular Genetics.  24:4078-4093. 2015
    2014 Distinct populations of label-retaining cells in the adult kidney are defined temporally and exhibit divergent regional distributions 2014
    2014 Ascorbic Acid in Cancer: A Renewed Hope?.  Journal of Cancer Science and Therapy.  06. 2014
    2012 Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model.  Journal of Clinical Investigation.  122:1777-1785. 2012
    2011 Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1 2011
    2008 Postdoc competencies.  Nature.  453:1282-1282. 2008
    2008 Contribution of intrarenal cells to cellular repair after acute kidney injury: Subcapsular implantation technique 2008
    2007 Detection of early changes in renal function using 99mTc-MAG3 imaging in a murine model of ischemia-reperfusion injury 2007
    2007 HOpe for contrast-induced acute kidney injury.  Kidney International.  72:907-909. 2007
    2005 Distribution of Rab GTPases in mouse kidney and comparison with vacuolar H+-ATPase 2005
    2005 The nitric oxide pathway modulates hemangioblast activity of adult hematopoietic stem cells.  Blood.  105:1916-1922. 2005
    2000 Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis. 2000
    2000 Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis 2000
    1998 Distribution of Na,K-ATPase is normal in the inner ear of a mouse with a null mutation of the glucocorticoid receptor.  Hearing Research.  124:146-154. 1998
    1997 Ca2+-ATPases in the cochlear duct.  Acta oto-laryngologica. Supplementum.  117:553-558. 1997
    1996 Appearance of glucocorticoid receptors in the inner ear of the mouse during development.  Acta oto-laryngologica. Supplementum.  116:721-725. 1996
    1996 Electrochemical potentials and potassium concentration profiles recorded from perilymph, endolymph and associated inner ear tissues in adrenalectomized rats.  Hearing Research.  96:151-156. 1996
    1996 In situ real-time sequential potentiometric determinations of potassium concentrations from three cochlear regions in noise-exposed rats.  European Archives of Oto-Rhino-Laryngology.  253:201-204. 1996
    1996 Na,K-ATPase α- and β-isoforms in the developing cochlea of the mouse.  Hearing Research.  100:143-149. 1996
    1996 Receptors for glucocorticoids in the human inner ear 1996
    1995 Combined effects of adrenalectomy and noise exposure on compound action potentials, endocochlear potentials and endolymphatic potassium concentrations.  Hearing Research.  91:79-86. 1995
    1995 De novo synthesis of glucocorticoid hormone regulated inner ear proteins in rats.  Hearing Research.  86:183-188. 1995
    1995 Effect of stress on cochlear glucocorticoid protein. II. Restraint.  Hearing Research.  92:120-125. 1995
    1995 Effect of stress on cochlear glucocorticoid protein: Acoustic stress.  Hearing Research.  82:135-138. 1995
    1995 Expression of na, k-ATPase α and β isoforms in the neonatal rat cochlea.  Acta oto-laryngologica. Supplementum.  115:497-503. 1995
    1995 Glucocorticoid receptor expression in the postnatal rat cochlea.  Hearing Research.  87:220-227. 1995
    1994 Effects of low-sodium, high-potassium dietary intake on cochlear lateral wall Na+,K+-ATPase.  European Archives of Oto-Rhino-Laryngology.  251:6-11. 1994
    1994 Expression of Na+,K+-ATPase α1 subunit mRNA in the developing rat cochlea.  Hearing Research.  80:31-37. 1994
    1994 Na,K-ATPase subunit isoform expression in the guinea pig endolymphatic sac.  ORL.  56:257-262. 1994
    1994 Na,K-ATPase α and β subunit isoform distribution in the rat cochlear and vestibular tissues.  Hearing Research.  75:151-160. 1994
    1993 Dynamics of Na,K-ATPase sites in lateral cochlear wall tissues of the rat.  European Archives of Oto-Rhino-Laryngology.  250:265-270. 1993
    1993 Localization of glucocorticoid receptors and glucocorticoid receptor mRNAs in the rat cochlea 1993
    1993 Tissue specific levels of glucocorticoid receptor within the rat inner ear.  Hearing Research.  64:205-210. 1993
    1992 Immunochemical detection of glucocorticoid receptors within rat cochlear and vestibular tissues.  Hearing Research.  60:199-204. 1992

    Research Overview

  • Sex differences and age effects in acute kidney injury; transgender kidney health and disease

    • Principal Investigator On

    Investigator On

    Teaching Overview

  • Dr. Curtis has done guest lectures on basic renal physiology (GBS 748VTC) and in advanced renal physiology (GBS 732). In addition, she serves as a lead discussant in small group discussions of case studies in scientific ethics as part of GRD717. Dr. Curtis also devised an annual seminar series entitled “Core Concepts in Kidney Research” which focuses on providing an integrated look at a field of research to illicit greater synergy and develop collaborations across laboratories. Dr. Curtis has also lectured in national forums on topics of career development.

    • Education And Training

  • UAB Medicine/Nephrology, Postdoctoral Research
  • UAB Microbiology, Postdoctoral Research
  • University of Florida Shands Cancer Center, Postdoctoral Research
  • Doctor of Philosophy in Cell / Cellular and Molecular Biology, University of Florida 2001
  • Bachelor of Science or Mathematics in Chemistry, University of Florida 1990
  • Bachelor of Science or Mathematics in Microbiology, University of Florida 1988

    • Full Name

  • Lisa Curtis