Selected Publications

Academic Article

Year Title Altmetric
2023 Mucociliary transport deficiency and disease progression in Syrian hamsters with SARS-CoV-2 infectionJCI Insight.  8. 2023
2023 Cortical Thinning in High-Grade Asymptomatic Carotid StenosisJournal of Stroke.  25:92-100. 2023
2023 Novel lower-extremity dexterity assessment for Parkinson’s disease: validation against measures of arm dexterity and general mobilityDisability and Rehabilitation.  45:291-300. 2023
2022 Researcher Identity Formation among Black Undergraduate Participants in a Summer Research Training ProgramThe Journal of Negro education.  91:101-111. 2022
2022 Preclinical evaluation of the epithelial sodium channel inhibitor AZD5634 and implications on human translation 2022
2022 Cortical and Subthalamic Nucleus Spectral Changes During Limb Movements in Parkinson's Disease Patients with and Without DystoniaMovement Disorders.  37:1683-1692. 2022
2022 Anthropometric Measures Correspond with Functional Motor Outcomes in Females with Rett SyndromeJournal of Pediatrics.  244:169-177.e3. 2022
2022 The spike-and-slab elastic net as a classification tool in Alzheimer's diseasePLoS One.  17. 2022
2022 Mucociliary Transport Deficiency and Disease Progression in Syrian Hamsters with SARS-CoV-2 Infection. 2022
2022 Artificial neural networks with a signed-rank objective function and applications 2022
2021 Analysis of eeg data using complex geometric structurizationNeural Computation.  33:1942-1969. 2021
2021 Twenty-five-year changes in office and ambulatory blood pressure: Results from the coronary artery risk development in young adults (cardia) studyAmerican Journal of Hypertension.  34:494-503. 2021
2021 NF106: A neurofibromatosis clinical trials consortium phase II trial of the MEK inhibitor mirdametinib (PD-0325901) in adolescents and adults with NF1-related plexiform neurofibromasJournal of Clinical Oncology.  39:797-806. 2021
2021 A Nearly Exact Discretization Scheme for the FitzHugh–Nagumo ModelDifferential Equations and Dynamical Systems2021
2020 Toileting Abilities Survey as a surrogate outcome measure for cognitive function: Findings from neuronopathic mucopolysaccharidosis II patients treated with idursulfase and intrathecal idursulfaseMolecular Genetics and Metabolism Reports.  25. 2020
2020 Ataluren/ivacaftor combination therapy: Two N-of-1 trials in cystic fibrosis patients with nonsense mutationsPediatric pulmonology. Supplement.  55:1838-1842. 2020
2020 Development of Predictive Equations for Nocturnal Hypertension and Nondipping Systolic Blood PressureJournal of the American Heart Association.  9. 2020
2020 Excess mucus viscosity and airway dehydration impact COPD airway clearanceEuropean Respiratory Journal.  55. 2020
2020 Is the type of neuraxial anesthesia associated with adverse neonatal outcomes among patients with preeclampsia?Journal of Neonatal-Perinatal Medicine.  13:331-337. 2020
2019 An R2 statistic for covariance model selection in the linear mixed modelJournal of Applied Statistics.  46:164-184. 2019
2019 Out-of-Clinic Sympathetic Activity Is Increased in Patients with Masked Uncontrolled HypertensionHypertension.  73:132-141. 2019
2018 Impact of bladder cancer on health-related quality of lifeBJU International.  121:549-557. 2018
2018 Assessing responsiveness over time of the PROMIS® pediatric symptom and function measures in cancer, nephrotic syndrome, and sickle cell diseaseQuality of Life Research.  27:249-257. 2018
2017 A test of separate hypotheses for comparing linear mixed models with non nested fixed effects 2017
2017 Early extubation in pediatric heart surgery across a spectrum of case complexity: Impact on hospital length of stay and chest tube daysProgress in Pediatric Cardiology.  45:63-68. 2017
2017 An R2 statistic for fixed effects in the generalized linear mixed modelJournal of Applied Statistics.  44:1086-1105. 2017
2017 Novel baseline predictors of adverse events during oral immunotherapy in children with peanut allergyJournal of Allergy and Clinical Immunology.  139:882-888.e5. 2017
2016 Predictors of Preference for Hospice Care Among Diverse Older Adults 2016
2016 Visit-to-Visit Variability in Blood Pressure Is Related to Late-Life Cognitive DeclineHypertension.  68:106-113. 2016
2016 Responsiveness of PROMIS® Pediatric Measures to Hospitalizations for Sickle Pain and Subsequent RecoveryPediatric Blood and Cancer.  63:1038-1045. 2016
2016 Plastic surgery in-training exam scores correlate with US medical licensing exam step 1 and 2 scores 2016
2016 The performance and association between patient-reported and performance-based measures of physical functioning in research on individuals with arthritisJournal of Rheumatology.  43:131-137. 2016
2015 Dietary Patterns and Cognitive Decline among Chinese Older AdultsEpidemiology.  26:758-768. 2015
2015 Outcomes of pediatric patients with abdominal sepsis requiring surgery and extracorporeal membrane oxygenation using the extracorporeal life support organization database 2015
2015 Weighing projections of physical decline in lung cancer surgery decisionsAmerican Journal of the Medical Sciences.  349:61-66. 2015
2014 Separability tests for high-dimensional, low-sample size multivariate repeated measures dataJournal of Applied Statistics.  41:2450-2461. 2014
2014 Public attitudes about lung cancer: Stigma, support, and predictors of supportJournal of Multidisciplinary Healthcare.  7:293-300. 2014
2014 Patient characteristics associated with favorable perceptions of patient-provider communication in early-stage lung cancer treatment 2014
2014 Kronecker product linear exponent AR(1) correlation structures for multivariate repeated measuresPLoS One.  9. 2014
2014 An Intervention to Decrease Stigma in Young Adults With Sickle Cell DiseaseWestern Journal of Nursing Research.  36:599-619. 2014
2014 An analysis of 24-h ambulatory blood pressure monitoring data using orthonormal polynomials in the linear mixed modelBlood Pressure Monitoring.  19:153-163. 2014
2014 Fish intake is associated with slower cognitive decline in chinese older adults 2014
2013 Erratum: Management of stage IIIA non-small cell lung cancer by thoracic surgeons in North America (Ann Thorac Surg (2012) 94 (922-928))Annals of Thoracic Surgery.  96:1532. 2013
2013 A circular LEAR correlation structure for cyclical longitudinal dataStatistical Methods in Medical Research.  22:296-306. 2013
2013 Preferences for arthritis interventions: Identifying similarities and differences among African Americans and whites with osteoarthritisArthritis Care and Research.  65:203-211. 2013
2013 Quality of life among long-term survivors of non-Hodgkin lymphoma: A follow-up studyJournal of Clinical Oncology.  31:272-279. 2013
2012 Management of stage IIIA non-small cell lung cancer by thoracic surgeons in North AmericaAnnals of Thoracic Surgery.  94:922-928. 2012
2012 Early-life soy exposure and age at menarchePaediatric and Perinatal Epidemiology.  26:163-175. 2012
2012 Fixed and random effects modelsWiley Interdisciplinary Reviews: Computational Statistics.  4:181-190. 2012
2011 Post-traumatic stress symptoms in long-term non-Hodgkin's lymphoma survivors: Does time heal?Journal of Clinical Oncology.  29:4526-4533. 2011
2011 Avoiding bias in mixed model inference for fixed effectsStatistics in Medicine.  30:2696-2707. 2011
2011 Disparities in postacute rehabilitation care for stroke: An analysis of the state inpatient databasesArchives of Physical Medicine and Rehabilitation.  92:1220-1229. 2011
2011 Disparities in post-acute rehabilitation care for joint replacementArthritis Care and Research.  63:1020-1030. 2011
2011 Early-life soy exposure and gender-role play behavior in childrenEnvironmental Health Perspectives.  119:1811-1816. 2011
2011 Estimating variance components and random effects using the box-cox transformation in the linear mixed model 2011
2010 Patient preferences for stroke rehabilitationTopics in Stroke Rehabilitation.  17:394-400. 2010
2010 A linear exponent AR(1) family of correlation structuresStatistics in Medicine.  29:1825-1838. 2010
2010 Factors associated with decisions to undergo surgery among patients with newly diagnosed early-stage lung cancerJournal of the American Medical Association.  303:2368-2376. 2010
2010 Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cellsJournal of Molecular Signaling.  5. 2010
2010 Real longitudinal data analysis for real people: Building a good enough mixed modelStatistics in Medicine.  29:504-520. 2010
2009 Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinomaOncogene.  28:2513-2523. 2009
2008 Nursing home deficiency resolution: Are the states following federal guidelines?Hallym International Journal of Aging: Gerontological Research, Policies and Programs in the New Millennium.  10:1-21. 2008
2008 An R2 statistic for fixed effects in the linear mixed modelStatistics in Medicine.  27:6137-6157. 2008
2008 Nursing home deficiencies: An exploratory study of interstate variations in regulatory activity 2008
2008 Fixed-effect variable selection in linear mixed models using R2 statisticsComputational Statistics and Data Analysis.  52:1896-1907. 2008
2007 Continuity of care and hypertension control in a university-based practice 2007
2007 Statistical tests with accurate size and power for balanced linear mixed modelsStatistics in Medicine.  26:3639-3660. 2007
2007 Testing transformations for the linear mixed modelComputational Statistics and Data Analysis.  51:4297-4307. 2007
2006 Comparing United States versus international medical school graduate physicians who serve African- American and wite ederlyHealth Services Research.  41:2155-2181. 2006
2006 Extending the Box-Cox transformation to the linear mixed model 2006
2006 A method for fitting regression splines with varying polynomial order in the linear mixed modelStatistics in Medicine.  25:513-527. 2006
2005 Physician-patient racial concordance, continuity of care, and patterns of care for hypertensionAmerican Journal of Public Health.  95:2186-2190. 2005
2005 Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: Implications for analysis of thymus functionJournal of Clinical Immunology.  25:462-472. 2005
2005 Prediction of 3-year developmental outcomes from sleep development over the preterm periodInfant Behavior and Development.  28:118-131. 2005
2005 Effect of olanzapine on body composition and energy expenditure in adults with first-episode psychosisAmerican Journal of Psychiatry.  162:118-123. 2005
2004 Obesity and type 2 diabetes mellitus: A population-based study of adolescentsJournal of Pediatric Endocrinology and Metabolism.  17:1633-1640. 2004
2003 Nontuberculous mycobacteria: I: Multicenter prevalence study in cystic fibrosisAmerican Journal of Respiratory and Critical Care Medicine.  167:828-834. 2003
2003 Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of cholineBiochemical Journal.  370:987-993. 2003
2002 HIV infection: Treatment outcomes in older and younger adultsJournal of the American Geriatrics Society.  50:603-607. 2002
2002 Deficiency in methionine, tryptophan, isoleucine, or choline induces apoptosis in cultured cells 2002
2002 Protease inhibitors are associated with a slowed progression of HIV-related renal diseasesClinical Nephrology.  57:336-341. 2002
2002 Randomized study of temporary hemodialysis cathetersInternational Journal of Artificial Organs.  25:40-44. 2002
2002 Screening for diabetes in an outpatient clinic populationJournal of General Internal Medicine.  17:23-28. 2002
2001 Results of a randomized, prospective, multicenter trial of mycophenolate mofetil versus azathioprine in the prevention of acute lung allograft rejectionTransplantation.  71:1772-1776. 2001
2001 Immunologic profile of human immunodeficiency virus-infected patients during viral remission and relapse on antiretroviral therapyJournal of Infectious Diseases.  183:1522-1525. 2001
2001 Identification of higher risk thin melanomas should be based on Breslow depth not Clark Level IVCancer.  91:983-991. 2001
2001 Effect of thymectomy on human peripheral blood T cell pools in myasthenia gravisJournal of Immunology.  166:2808-2817. 2001
2001 Impact of sodium and ultrafiltration profiling on hemodialysis-related symptomsJournal of the American Society of Nephrology.  12:151-156. 2001
2001 A prospective evaluation of health-related quality of life after ileal pouch anal anastomosis for ulcerative colitisAmerican Journal of Gastroenterology.  96:1480-1485. 2001
2001 Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteriaStroke.  32:1091-1096. 2001
2001 Linear equality constraints in the general linear mixed modelBiometrics.  57:1185-1190. 2001
2000 Modern statistical techniques for the analysis of longitudinal data in biomedical researchPediatric pulmonology. Supplement.  30:330-344. 2000
2000 Significance of blood stream infection after lung transplantation: Analysis in 176 consecutive patientsTransplantation.  69:2360-2366. 2000
2000 A randomized trial of 3,4-diaminopyridine in Lambert-Eaton myasthenic syndromeNeurology.  54:603-607. 2000
2000 Depression and other determinants of values placed on current health state by stroke patients: Evidence from the VA acute stroke (VASt) studyStroke.  31:2603-2609. 2000
2000 Predictive Value of Single-Fiber Electromyography in the Extensor Digitorum Communis Muscle of Patients with Ocular Myasthenia Gravis: A Retrospective StudyJournal of Clinical Neuromuscular Disease.  2:6-9. 2000
2000 Racial variation in initial stroke severityStroke.  31:563-567. 2000
1999 Attitudes of African Americans toward participation in medical researchJournal of Applied Social Psychology.  29:552-574. 1999
1998 Temporal organization of sleep-wake states in preterm infantsDevelopmental Psychobiology.  33:257-269. 1998
1998 Modeling development of sleep-wake behaviors. II. Results of two cohorts of pretermsPhysiology and Behavior.  63:319-328. 1998
1998 Modeling development of sleep-wake behaviors: I. Using the mixed general linear modelPhysiology and Behavior.  63:311-318. 1998
1998 Measurement error in dietary data: Implications for the epidemiologic study of the diet-disease relationshipEuropean Journal of Clinical Nutrition.  52:722-727. 1998
1997 Acute safety and effects on mucociliary clearance of aerosolized uridine 5′-triphosphate ± amiloride in normal human adultsPediatric Pulmonology.  23:319. 1997
1997 Airway deposition and clearance and systemic pharmacokinetics of amiloride following aerosolization with an ultrasonic nebulizer to normal airwaysChest.  112:1283-1290. 1997
1997 Longitudinal analysis of pulmonary function decline in patients with cystic fibrosisJournal of Pediatrics.  131:809-814. 1997
1996 Acute safety and effects on mucociliary clearance of aerosolized uridine 5'-triphosphate ± amiloride in normal human adultsAmerican Journal of Respiratory and Critical Care Medicine.  154:217-223. 1996
1996 Relief of the 'air hunger' of breathholding A role for pulmonary stretch receptorsRespiratory Physiology and Neurobiology.  103:221-232. 1996
1995 A controlled study of adenoviral-vector–mediated gene transfer in the nasal epithelium of patients with cystic fibrosisNew England Journal of Medicine.  333:823-831. 1995
1995 Effect of measurement error in testing separate linear modelsJournal of Statistical Computation and Simulation.  52:205-216. 1995
1995 Errors-in-variables and the Box-Cox transformationComputational Statistics and Data Analysis.  20:131-140. 1995
1995 Racial differences in the patterns of preterm delivery in central North Carolina, USAPaediatric and Perinatal Epidemiology.  9:281-295. 1995
1995 Relief of distress of breathholding: separate effects of expiration and inspirationRespiratory Physiology and Neurobiology.  101:41-46. 1995
1994 An alternative approach to estimation in the functional measurement error problem 1994
1994 Approximating Fisher’s information for the functional measurement error modelJournal of Applied Statistics.  21:205-219. 1994
1994 Beyond couvade: Pregnancy symptoms in couples with a history of infertilityHealth Care for Women International.  15:537-548. 1994
1994 Pathologic apnea and brief respiratory pauses in preterm infants: Relation to sleep stateNursing Research.  43:293-300. 1994
1994 The Fowler breathholding study revisited: continuous rating of respiratory sensationRespiratory Physiology and Neurobiology.  95:53-66. 1994
1992 Nontuberculous mycobacteria in adult patients with cystic fibrosisChest.  102:70-75. 1992
1991 Aerosolized amiloride as treatment of cystic fibrosis lung disease: A pilot studyAdvances in Experimental Medicine and Biology.  290:119-132. 1991
1990 Aerosolized Amiloride for the Treatment of Lung Disease in Cystic FibrosisNew England Journal of Medicine.  323:996-998. 1990
1990 A Pilot Study of Aerosolized Amiloride for the Treatment of Lung Disease in Cystic FibrosisNew England Journal of Medicine.  322:1189-1194. 1990
1990 Aerosolized amiloride for the treatment of lung disease in cystic fibrosis (Reply)New England Journal of Medicine.  323:997-998. 1990


Year Title Altmetric
2007 8 Mixed Models.  Ed. 27.  2007
2000 35 Bridging the biostatistics-epidemiology gap.  Ed. 18.  2000


Year Title Altmetric
2011 Mixed Models.  146-173. 2011
2011 5 Mixed Models.  146-173. 2011

Investigator On

  • Building and InnovatinG: Digital heALTH Technology and Analytics (BIGDATA)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Building and InnovatinG: Digital heAlth Technology and Analytics (BIGDATA) - Methodologic Core  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • CHEER Center for the Study of Community Health  awarded by CDC - Centers for Disease Control and Prevention/DHHS
  • CHEER Center for the Study of Community Health  awarded by National Center for Chronic Disease Prevention & Health Promo./CDC/DHHS
  • CHEER Center for the Study of Community Health  awarded by CDC - Centers for Disease Control and Prevention/DHHS
  • CHEER Center for the Study of Community Health - Admin Core  awarded by CDC - Centers for Disease Control and Prevention/DHHS
  • CHEER Center for the Study of Community Health - Core A - Admin  awarded by National Center for Chronic Disease Prevention & Health Promo./CDC/DHHS
  • CREST-2 Statistical and Data Coordinating Center - (SDCC)  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • CREST-2 Statistical and Data Coordinating Center - SDCC  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Continuation of the Coordinating Center for the Chronic Renal Insufficiency Cohort (CRIC) Study  awarded by University of Pennsylvania
  • Incorporation of a Hypertension Working Group into the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Incorporation of a Hypertension Working Group into the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Private Grant  awarded by ELECTROMED, INC.
  • StatNet-University of Alabama at Birmingham  awarded by Cystic Fibrosis Foundation ^
  • Therapeutics Development Center Award  awarded by Cystic Fibrosis Foundation ^
  • Therapeutics Development Center Award  awarded by Cystic Fibrosis Foundation ^
  • Translational Program in CFTR-Related Airway Diseases  awarded by Cystic Fibrosis Foundation ^
  • UAB Alzheimer's Disease Research Center  awarded by National Institute on Aging/NIH/DHHS
  • UAB Alzheimer's Disease Research Center - Admin Core  awarded by NIH - National Institutes of Health/DHHS
  • Education And Training

  • Doctor of Philosophy in Biostatistics, University of North Carolina System : Chapel Hill 1990
  • Full Name

  • Lloyd Edwards
  • Fax

  • 205-975-2540