• Nina Kraguljac is a board-certified psychiatrist and Assistant Professor in the Department of Psychiatry and Behavioral Neurobiology at the University of Alabama at Birmingham (UAB). She received her medical degree from Paracelsus Medical University in Salzburg, Austria in 2008 and completed her residency training in General Psychiatry at UAB in 2013.

    Her research interests focus on the utilization of multimodal neuroimaging techniques, pharmacological modelling, and computationally advanced data analytics in an effort to better understand disease processes underlying psychosis spectrum disorders.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Dorsal striatial hypoconnectivity predicts antipsychotic medication treatment response in first-episode psychosis and unmedicated patients with schizophreniaBrain and Behavior.  12. 2022
    2022 Risks and Benefits of Cannabis and Cannabinoids in PsychiatryAmerican Journal of Psychiatry.  179:98-109. 2022
    2022 Contrasting Case-Control and Normative Reference Approaches to Capture Clinically Relevant Structural Brain Abnormalities in Patients with First-Episode Psychosis Who Are Antipsychotic NaiveJAMA Psychiatry2022
    2022 Hippocampal Dysconnectivity and Altered Glutamatergic Modulation of the Default Mode Network: A Combined Resting-State Connectivity and Magnetic Resonance Spectroscopy Study in SchizophreniaBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  7:108-118. 2022
    2021 Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggest Dentate Gyrus Pathology Linked to NMDA Receptor HypofunctionBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  6:1185-1192. 2021
    2021 White matter integrity, duration of untreated psychosis, and antipsychotic treatment response in medication-naïve first-episode psychosis patientsMolecular Psychiatry.  26:5347-5356. 2021
    2021 Evaluating the Machine Learning Literature: A Primer and User's Guide for PsychiatristsAmerican Journal of Psychiatry.  178:715-729. 2021
    2021 White Matter Neurometabolic Signatures Support the Deficit and Nondeficit Distinction in Antipsychotic-Naïve First-Episode Psychosis PatientsSchizophrenia Bulletin.  47:1068-1076. 2021
    2021 Neuroimaging Biomarkers in SchizophreniaAmerican Journal of Psychiatry.  178:509-521. 2021
    2021 Reinforcement learning abnormalities in the attenuated psychosis syndrome and first episode psychosisEuropean Neuropsychopharmacology.  47:11-19. 2021
    2021 Neuroimaging as a Window Into the Pathophysiological Mechanisms of SchizophreniaFrontiers in Psychiatry.  12. 2021
    2021 A multimodal neuroimaging study investigating resting-state connectivity, glutamate and GABA at 7 T in first-episode psychosisJournal of Psychiatry and Neuroscience.  46:E702-E710. 2021
    2021 Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic TreatmentNeuropsychobiology: international journal of experimental and clinical research in biological psychiatry, pharmacopsychiatry, biological psychology, pharmacopsychology and pharmacoelectroencephalography.  80:12-24. 2021
    2021 Salience network glutamate and brain connectivity in medication-naïve first episode patients – A multimodal magnetic resonance spectroscopy and resting state functional connectivity MRI studyNeuroImage: Clinical.  32. 2021
    2021 Structural and Functional Default Mode Network Connectivity and Antipsychotic Treatment Response in Medication-Naïve First Episode Psychosis Patients 2021
    2020 A multimodal magnetoencephalography 7 T fMRI and 7 T proton MR spectroscopy study in first episode psychosisnpj Schizophrenia.  6. 2020
    2020 Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosisTranslational Psychiatry.  10. 2020
    2020 Neurometabolic correlates of 6 and 16 weeks of treatment with risperidone in medication-naive first-episode psychosis patientsTranslational Psychiatry.  10. 2020
    2020 White matter and neurite morphology differ in psychogenic nonepileptic seizuresAnnals of Clinical and Translational Neurology.  7:1973-1984. 2020
    2020 Aberrant static and dynamic functional patterns of frontoparietal control network in antipsychotic-naïve first-episode psychosis subjectsHuman Brain Mapping.  41:2999-3008. 2020
    2020 COVID-19: Facts, Cultural Considerations, and Risk of StigmatizationJournal of Transcultural Nursing.  31:326-332. 2020
    2020 A Prospective Longitudinal Investigation of Cortical Thickness and Gyrification in SchizophreniaCanadian Journal of Psychiatry.  65:381-391. 2020
    2020 Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode PsychosisBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  5:231-238. 2020
    2020 Baseline Functional Connectivity Predicts Connectivity Changes Due to a Small Dose of Midazolam in Older AdultsAnesthesia and Analgesia.  130:224-232. 2020
    2020 The role of glutamate and GABA in cognitive dysfunction in schizophrenia and mood disorders – A systematic review of magnetic resonance spectroscopy studiesSchizophrenia Research2020
    2019 A longitudinal neurite and free water imaging study in patients with a schizophrenia spectrum disorderNeuropsychopharmacology.  44:1932-1939. 2019
    2019 Ketamine induced changes in regional cerebral blood flow, interregional connectivity patterns, and glutamate metabolismJournal of Psychiatric Research.  117:108-115. 2019
    2019 A longitudinal magnetic resonance spectroscopy study investigating effects of risperidone in the anterior cingulate cortex and hippocampus in schizophreniaSchizophrenia Research.  210:239-244. 2019
    2019 Micro- and Macrostructural White Matter Integrity in Never-Treated and Currently Unmedicated Patients With Schizophrenia and Effects of Short-Term Antipsychotic TreatmentBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  4:462-471. 2019
    2019 Cognitive control network dysconnectivity and response to antipsychotic treatment in schizophreniaSchizophrenia Research.  204:262-270. 2019
    2019 Relationship Between Cortical Excitation and Inhibition and Task-Induced Activation and Deactivation: A Combined Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study at 7T in First-Episode PsychosisBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  4:121-130. 2019
    2019 Examining resting-state functional connectivity in first-episode schizophrenia with 7T fMRI and MEGNeuroImage: Clinical.  24. 2019
    2018 Gyrification Connectomes in Unmedicated Patients With Schizophrenia and Following a Short Course of Antipsychotic Drug TreatmentFrontiers in Psychiatry.  9. 2018
    2018 Evaluation of fronto-striatal networks during cognitive control in unmedicated patients with schizophrenia and the effect of antipsychotic medicationnpj Schizophrenia.  4. 2018
    2018 Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patientsPsychiatry Research: Neuroimaging.  281:101-106. 2018
    2018 A Longitudinal Multimodal Neuroimaging Study to Examine Relationships Between Resting State Glutamate and Task Related BOLD Response in SchizophreniaFrontiers in Psychiatry.  9. 2018
    2018 Four-way multimodal fusion of 7 T imaging data using an mCCA+jICA model in first-episode schizophreniaHuman Brain Mapping.  39:1475-1488. 2018
    2018 Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggests Dentate Gyrus Pathology Linked to N-Methyl-D-Aspartate Receptor HypofunctionBiological Psychiatry: Cognitive Neuroscience and Neuroimaging.  3:231-238. 2018
    2018 Paving the way for targeted drug development in schizophreniaJAMA Psychiatry.  75:19-20. 2018
    2017 Brain structure, function, and neurochemistry in schizophrenia and bipolar disorder- A systematic review of the magnetic resonance neuroimaging literaturenpj Schizophrenia.  3. 2017
    2017 A rare presentation of auto-emasculation in a patient with schizoaffective disorder: Management with clozapine.Clinical Schizophrenia and Related Psychoses2017
    2017 Ketamine modulates hippocampal neurochemistry and functional connectivity: A combined magnetic resonance spectroscopy and resting-state fMRI study in healthy volunteersMolecular Psychiatry.  22:562-569. 2017
    2017 Risperidone effects on brain dynamic connectivity-A prospective resting-state fMRI study in SchizophreniaFrontiers in Psychiatry.  8. 2017
    2016 Aberrant hippocampal connectivity in unmedicated patients with schizophrenia and effects of antipsychotic medication: A longitudinal resting state functional mri studySchizophrenia Bulletin.  42:1046-1055. 2016
    2016 Change in brain network topology as a function of treatment response in schizophrenia: A longitudinal resting-state fMRI study using graph theorynpj Schizophrenia.  2. 2016
    2016 A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophreniaSchizophrenia Research.  170:341-350. 2016
    2016 Abnormalities in large scale functional networks in unmedicated patients with schizophrenia and effects of risperidoneNeuroImage: Clinical.  10:146-158. 2016
    2016 Rapid clozapine titration in an acutely agitated patient with schizoaffective disorder a case reportJournal of Clinical Psychopharmacology.  36:276-277. 2016
    2015 Contribution of substantia nigra glutamate to prediction error signals in schizophrenia: A combined magnetic resonance spectroscopy/functional imaging studynpj Schizophrenia.  1. 2015
    2014 Hippocampal-parietal dysconnectivity and glutamate abnormalities in unmedicated patients with schizophreniaThe Hippocampus.  24:1524-1532. 2014
    2014 Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophreniaNeuropsychopharmacology.  39:1020-1030. 2014
    2014 In replyJAMA Psychiatry.  71:339-340. 2014
    2013 Memory deficits in Schizophrenia: A selective review of functional magnetic resonance imaging (fMRI) studiesBehavioral Sciences.  3:330-347. 2013
    2013 Proton magnetic resonance spectroscopy of the substantia nigra in schizophreniaSchizophrenia Research.  147:348-354. 2013
    2013 Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophreniaJAMA Psychiatry.  70:1294-1302. 2013
    2012 Regional decoupling of n-acetyl-aspartate and glutamate in schizophreniaNeuropsychopharmacology.  37:2635-2642. 2012
    2012 Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imagingSchizophrenia Research.  140:136-142. 2012
    2012 Neurometabolites in schizophrenia and bipolar disorder - A systematic review and meta-analysisPsychiatry Research: Neuroimaging.  203:111-125. 2012
    2009 Efficacy of omega-3 fatty acids in mood disorders - A systematic review and metaanalysisPsychopharmacology bulletin.  42:39-54. 2009

    Full Name

  • Nina Kraguljac