Positions

Overview

  • Nina Kraguljac is a board-certified psychiatrist and Assistant Professor in the Department of Psychiatry and Behavioral Neurobiology at the University of Alabama at Birmingham (UAB). She received her medical degree from Paracelsus Medical University in Salzburg, Austria in 2008 and completed her residency training in General Psychiatry at UAB in 2013.

    Her research interests focus on the utilization of multimodal neuroimaging techniques, pharmacological modelling, and computationally advanced data analytics in an effort to better understand disease processes underlying psychosis spectrum disorders.

    • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Dorsal striatial hypoconnectivity predicts antipsychotic medication treatment response in first-episode psychosis and unmedicated patients with schizophrenia.  Brain and Behavior.  12. 2022
    2022 Risks and Benefits of Cannabis and Cannabinoids in Psychiatry.  American Journal of Psychiatry.  179:98-109. 2022
    2022 Contrasting Case-Control and Normative Reference Approaches to Capture Clinically Relevant Structural Brain Abnormalities in Patients with First-Episode Psychosis Who Are Antipsychotic Naive.  JAMA Psychiatry.  2022
    2022 Hippocampal Dysconnectivity and Altered Glutamatergic Modulation of the Default Mode Network: A Combined Resting-State Connectivity and Magnetic Resonance Spectroscopy Study in Schizophrenia.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  7:108-118. 2022
    2021 Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggest Dentate Gyrus Pathology Linked to NMDA Receptor Hypofunction.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  6:1185-1192. 2021
    2021 White matter integrity, duration of untreated psychosis, and antipsychotic treatment response in medication-naïve first-episode psychosis patients.  Molecular Psychiatry.  26:5347-5356. 2021
    2021 Evaluating the Machine Learning Literature: A Primer and User's Guide for Psychiatrists.  American Journal of Psychiatry.  178:715-729. 2021
    2021 White Matter Neurometabolic Signatures Support the Deficit and Nondeficit Distinction in Antipsychotic-Naïve First-Episode Psychosis Patients.  Schizophrenia Bulletin.  47:1068-1076. 2021
    2021 Neuroimaging Biomarkers in Schizophrenia.  American Journal of Psychiatry.  178:509-521. 2021
    2021 Reinforcement learning abnormalities in the attenuated psychosis syndrome and first episode psychosis.  European Neuropsychopharmacology.  47:11-19. 2021
    2021 Neuroimaging as a Window Into the Pathophysiological Mechanisms of Schizophrenia.  Frontiers in Psychiatry.  12. 2021
    2021 A multimodal neuroimaging study investigating resting-state connectivity, glutamate and GABA at 7 T in first-episode psychosis.  Journal of Psychiatry and Neuroscience.  46:E702-E710. 2021
    2021 Neural Signatures of Memory Encoding in Schizophrenia Are Modulated by Antipsychotic Treatment.  Neuropsychobiology: international journal of experimental and clinical research in biological psychiatry, pharmacopsychiatry, biological psychology, pharmacopsychology and pharmacoelectroencephalography.  80:12-24. 2021
    2021 Salience network glutamate and brain connectivity in medication-naïve first episode patients – A multimodal magnetic resonance spectroscopy and resting state functional connectivity MRI study.  NeuroImage: Clinical.  32. 2021
    2021 Structural and Functional Default Mode Network Connectivity and Antipsychotic Treatment Response in Medication-Naïve First Episode Psychosis Patients 2021
    2020 A multimodal magnetoencephalography 7 T fMRI and 7 T proton MR spectroscopy study in first episode psychosis.  npj Schizophrenia.  6. 2020
    2020 Hippocampal glutamate and hippocampus subfield volumes in antipsychotic-naive first episode psychosis subjects and relationships to duration of untreated psychosis.  Translational Psychiatry.  10. 2020
    2020 Neurometabolic correlates of 6 and 16 weeks of treatment with risperidone in medication-naive first-episode psychosis patients.  Translational Psychiatry.  10. 2020
    2020 White matter and neurite morphology differ in psychogenic nonepileptic seizures.  Annals of Clinical and Translational Neurology.  7:1973-1984. 2020
    2020 Aberrant static and dynamic functional patterns of frontoparietal control network in antipsychotic-naïve first-episode psychosis subjects.  Human Brain Mapping.  41:2999-3008. 2020
    2020 COVID-19: Facts, Cultural Considerations, and Risk of Stigmatization.  Journal of Transcultural Nursing.  31:326-332. 2020
    2020 A Prospective Longitudinal Investigation of Cortical Thickness and Gyrification in Schizophrenia.  Canadian Journal of Psychiatry.  65:381-391. 2020
    2020 Duration of Untreated Psychosis Correlates With Brain Connectivity and Morphology in Medication-Naïve Patients With First-Episode Psychosis.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  5:231-238. 2020
    2020 Baseline Functional Connectivity Predicts Connectivity Changes Due to a Small Dose of Midazolam in Older Adults.  Anesthesia and Analgesia.  130:224-232. 2020
    2020 The role of glutamate and GABA in cognitive dysfunction in schizophrenia and mood disorders – A systematic review of magnetic resonance spectroscopy studies.  Schizophrenia Research.  2020
    2019 A longitudinal neurite and free water imaging study in patients with a schizophrenia spectrum disorder.  Neuropsychopharmacology.  44:1932-1939. 2019
    2019 Ketamine induced changes in regional cerebral blood flow, interregional connectivity patterns, and glutamate metabolism.  Journal of Psychiatric Research.  117:108-115. 2019
    2019 A longitudinal magnetic resonance spectroscopy study investigating effects of risperidone in the anterior cingulate cortex and hippocampus in schizophrenia.  Schizophrenia Research.  210:239-244. 2019
    2019 Micro- and Macrostructural White Matter Integrity in Never-Treated and Currently Unmedicated Patients With Schizophrenia and Effects of Short-Term Antipsychotic Treatment.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  4:462-471. 2019
    2019 Cognitive control network dysconnectivity and response to antipsychotic treatment in schizophrenia.  Schizophrenia Research.  204:262-270. 2019
    2019 Relationship Between Cortical Excitation and Inhibition and Task-Induced Activation and Deactivation: A Combined Magnetic Resonance Spectroscopy and Functional Magnetic Resonance Imaging Study at 7T in First-Episode Psychosis.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  4:121-130. 2019
    2019 Examining resting-state functional connectivity in first-episode schizophrenia with 7T fMRI and MEG.  NeuroImage: Clinical.  24. 2019
    2018 Gyrification Connectomes in Unmedicated Patients With Schizophrenia and Following a Short Course of Antipsychotic Drug Treatment.  Frontiers in Psychiatry.  9. 2018
    2018 Evaluation of fronto-striatal networks during cognitive control in unmedicated patients with schizophrenia and the effect of antipsychotic medication.  npj Schizophrenia.  4. 2018
    2018 Neurometabolic abnormalities in the associative striatum in antipsychotic-naïve first episode psychosis patients.  Psychiatry Research: Neuroimaging.  281:101-106. 2018
    2018 A Longitudinal Multimodal Neuroimaging Study to Examine Relationships Between Resting State Glutamate and Task Related BOLD Response in Schizophrenia.  Frontiers in Psychiatry.  9. 2018
    2018 Four-way multimodal fusion of 7 T imaging data using an mCCA+jICA model in first-episode schizophrenia.  Human Brain Mapping.  39:1475-1488. 2018
    2018 Mnemonic Discrimination Deficits in First-Episode Psychosis and a Ketamine Model Suggests Dentate Gyrus Pathology Linked to N-Methyl-D-Aspartate Receptor Hypofunction.  Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  3:231-238. 2018
    2018 Paving the way for targeted drug development in schizophrenia.  JAMA Psychiatry.  75:19-20. 2018
    2017 Brain structure, function, and neurochemistry in schizophrenia and bipolar disorder- A systematic review of the magnetic resonance neuroimaging literature.  npj Schizophrenia.  3. 2017
    2017 A rare presentation of auto-emasculation in a patient with schizoaffective disorder: Management with clozapine..  Clinical Schizophrenia and Related Psychoses.  2017
    2017 Ketamine modulates hippocampal neurochemistry and functional connectivity: A combined magnetic resonance spectroscopy and resting-state fMRI study in healthy volunteers.  Molecular Psychiatry.  22:562-569. 2017
    2017 Risperidone effects on brain dynamic connectivity-A prospective resting-state fMRI study in Schizophrenia.  Frontiers in Psychiatry.  8. 2017
    2016 Aberrant hippocampal connectivity in unmedicated patients with schizophrenia and effects of antipsychotic medication: A longitudinal resting state functional mri study.  Schizophrenia Bulletin.  42:1046-1055. 2016
    2016 Change in brain network topology as a function of treatment response in schizophrenia: A longitudinal resting-state fMRI study using graph theory.  npj Schizophrenia.  2. 2016
    2016 A combined diffusion tensor imaging and magnetic resonance spectroscopy study of patients with schizophrenia.  Schizophrenia Research.  170:341-350. 2016
    2016 Abnormalities in large scale functional networks in unmedicated patients with schizophrenia and effects of risperidone.  NeuroImage: Clinical.  10:146-158. 2016
    2016 Rapid clozapine titration in an acutely agitated patient with schizoaffective disorder a case report.  Journal of Clinical Psychopharmacology.  36:276-277. 2016
    2015 Contribution of substantia nigra glutamate to prediction error signals in schizophrenia: A combined magnetic resonance spectroscopy/functional imaging study.  npj Schizophrenia.  1. 2015
    2014 Hippocampal-parietal dysconnectivity and glutamate abnormalities in unmedicated patients with schizophrenia.  The Hippocampus.  24:1524-1532. 2014
    2014 Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophrenia.  Neuropsychopharmacology.  39:1020-1030. 2014
    2014 In reply.  JAMA Psychiatry.  71:339-340. 2014
    2013 Memory deficits in Schizophrenia: A selective review of functional magnetic resonance imaging (fMRI) studies.  Behavioral Sciences.  3:330-347. 2013
    2013 Proton magnetic resonance spectroscopy of the substantia nigra in schizophrenia.  Schizophrenia Research.  147:348-354. 2013
    2013 Increased hippocampal glutamate and volumetric deficits in unmedicated patients with schizophrenia.  JAMA Psychiatry.  70:1294-1302. 2013
    2012 Regional decoupling of n-acetyl-aspartate and glutamate in schizophrenia.  Neuropsychopharmacology.  37:2635-2642. 2012
    2012 Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging.  Schizophrenia Research.  140:136-142. 2012
    2012 Neurometabolites in schizophrenia and bipolar disorder - A systematic review and meta-analysis.  Psychiatry Research: Neuroimaging.  203:111-125. 2012
    2009 Efficacy of omega-3 fatty acids in mood disorders - A systematic review and metaanalysis.  Psychopharmacology bulletin.  42:39-54. 2009

    Full Name

  • Nina Kraguljac