Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors.Cancer Research.  81:5089-5101. 2021
2021 The Emerging Role of Suppressors of Cytokine Signaling (SOCS) in the Development and Progression of Leukemia.Cancers.  13. 2021
2021 RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.Journal of Clinical Investigation.  131. 2021
2021 Metabolic Reprogramming and Cell Adhesion in Acute Leukemia Adaptation to the CNS Niche.Frontiers in Cell and Developmental Biology.  9:767510. 2021
2019 Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemiaCancer Science.  110:1931-1946. 2019
2018 Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent.Oncotarget.  9:36867-36877. 2018
2018 High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL. 2018
2018 Drugging DNA repair to target T-ALL cells.Leukemia and Lymphoma.  59:1746-1749. 2018
2018 Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor CellsCell Reports.  23:3127-3136. 2018
2018 Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy.PLoS One.  13:e0193849. 2018
2018 Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL.Biomarker Research.  6:27. 2018
2017 Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia.Pediatric Blood and Cancer.  64. 2017
2017 Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia.Pediatric Blood and Cancer.  64. 2017
2017 CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.Leukemia.  31:255-258. 2017
2016 Dynamic pre-BCR homodimers fine-tune autonomous survival signals in B cell precursor acute lymphoblastic leukemia.Science Signaling.  9:ra116. 2016
2016 MLL rearrangements impact outcome in HOXA-deregulated T-lineage acute lymphoblastic leukemia: A Children's Oncology Group StudyLeukemia.  30:1909-1912. 2016
2016 Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.Oncotarget.  7:33960-33982. 2016
2014 Pyrosequencing for classification of human FcγRIIIA allotypes: a comparison with PCR-based techniques.Molecular Diagnosis and Therapy.  18:665-673. 2014
2014 The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.Toxicology in Vitro.  28:282-291. 2014
2013 Macrophage and NK-mediated killing of precursor-B acute lymphoblastic leukemia cells targeted with a-fucosylated anti-CD19 humanized antibodies.Leukemia.  27:1263-1274. 2013
2011 GSI-I (Z-LLNle-CHO) inhibits γ-secretase and the proteosome to trigger cell death in precursor-B acute lymphoblastic leukemia.Leukemia.  25:1135-1146. 2011
2011 Evaluation of cytotoxicity of new trans-palladium(II) complex in human cells in vitro.Acta poloniae pharmaceutica.  68:127-136. 2011
2010 The Vibrio parahaemolyticus Type III Secretion Systems manipulate host cell MAPK for critical steps in pathogenesis.BMC Microbiology.  10:329. 2010
2010 Genotoxic effects of irinotecan combined with the novel platinum(II) complexes in human cancer cells.Chemico-Biological Interactions.  188:66-74. 2010
2007 Analysis of aclarubicin-induced cell death in human fibroblasts.Cell Biology International.  31:1049-1056. 2007
2007 Genotoxicity of novel trans-platinum(II) complex with diethyl (pyridin-4-ylmethyl)phosphate in human non-small cell lung cancer cells A549.Chemico-Biological Interactions.  168:135-142. 2007
2005 Synthesis, spectroscopy and antiproliferative activity of cis- and trans-platinum(II) complexes with diethyl (pyridin-4-ylmethyl)phosphate. X-ray crystal structure of trans-Pt(II) complex.Journal of Inorganic Biochemistry.  99:2024-2031. 2005

Education And Training

  • Doctor of Philosophy Level Degree in Biology / Biological Sciences, University of Lodz 2007
  • Full Name

  • Ksenia Matlawska-Wasowska