Positions

Selected Publications

Academic Article

Year Title Altmetric
2023 Patient-reported geriatric assessment-based frailty index among older adults with gastrointestinal malignancies.  Journal of the American Geriatrics Society.  71:136-144. 2023
2022 Detection of mitochondrial DNA mutations in circulating mitochondria-originated extracellular vesicles for potential diagnostic applications in pancreatic adenocarcinoma.  Scientific Reports.  12. 2022
2022 Pain among older adults with gastrointestinal malignancies- results from the cancer and aging resilience evaluation (CARE) Registry.  Supportive Care in Cancer.  30:9793-9801. 2022
2022 Differences in Pretreatment Frailty Across Gastrointestinal Cancers in Older Adults: Results from the Cancer and Aging Resilience Evaluation Registry.  Jco Oncology Practice.  18:E1796-E1806. 2022
2022 Geriatric Assessment Predictors of 1-Year Mortality in Older Adults With GI Malignancies: A Survival Tree Analysis.  JCO Clinical Cancer Informatics.  6:e2200065. 2022
2022 Molecular Characterization of KRAS Wild-type Tumors in Patients with Pancreatic Adenocarcinoma.  Clinical Cancer Research.  28:2704-2714. 2022
2022 Racial disparities in frailty and geriatric assessment impairments in older adults with cancer in the Deep South: Results from the CARE Registry.  Cancer.  128:2313-2319. 2022
2022 DCZ0415, a small-molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β-catenin pathway in colorectal cancer.  Molecular Oncology.  16:1728-1745. 2022
2022 Perfusion Change of Hepatocellular Carcinoma During Atezolizumab plus Bevacizumab Treatment: A Pilot Study.  Journal of Gastrointestinal Cancer.  2022
2021 Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients.  npj Precision Oncology.  5. 2021
2021 Genomic landscape of angiosarcoma: A targeted and immunotherapy biomarker analysis.  Cancers.  13. 2021
2021 Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS–MAPK pathway and TP53 as potential predictors of immunotherapy efficacy.  Annals of Oncology.  32:906-916. 2021
2021 The landscape of alterations in DNA damage response pathways in colorectal cancer.  Clinical Cancer Research.  27:3234-3242. 2021
2021 The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens 2021
2021 Clinical and Hematological Predictors of High-Grade Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors.  Journal of Clinical Medicine Research.  13:268-275. 2021
2020 Usefulness of Restaging Pelvis Magnetic Resonance Imaging After Neoadjuvant Concurrent Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer.  Clinical Colorectal Cancer.  19:e281-e287. 2020
2020 Exosomal formulation escalates cellular uptake of honokiol leading to the enhancement of its antitumor efficacy.  ACS Omega.  5:23299-23307. 2020
2020 Comprehensive analysis of expression, clinicopathological association and potential prognostic significance of rabs in pancreatic cancer.  International Journal of Molecular Sciences.  21:1-14. 2020
2020 Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review.  Journal of Cancer Research and Therapeutics.  16:950-954. 2020
2020 Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.  Journal of Biological Chemistry.  295:8413-8424. 2020
2020 Prolonged response to liposomal irinotecan in a patient with stage iv pancreatic/bile duct cancer previously treated with FOLFIRINOX and gemcitabine plus nab-paclitaxel 2020
2019 Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications.  Scientific Reports.  9. 2019
2019 The Prevalence of DPYD*9A (c.85T>C) Genotype and the Genotype-Phenotype Correlation in Patients with Gastrointestinal Malignancies Treated With Fluoropyrimidines: Updated Analysis.  Clinical Colorectal Cancer.  18:e280-e286. 2019
2019 Exosomal markers (CD63 and CD9) expression and their prognostic significance using immunohistochemistry in patients with pancreatic ductal adenocarcinoma.  Journal of Gastrointestinal Oncology.  10:695-702. 2019
2019 Vitamin B12 deficiency presenting as pseudothrombotic microangiopathy: A case report and literature review.  Clinical Pharmacology: Advances and Applications.  11:127-131. 2019
2018 Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines.  Journal of Gastrointestinal Oncology.  9:416-424. 2018
2017 Molecular drivers of pancreatic cancer pathogenesis: Looking inward to move forward.  International Journal of Molecular Sciences.  18. 2017
2017 Syndrome of Inappropriate Anti-Diuretic Hormone Secretion Secondary to Strongyloides stercoralis Infection in an Allogeneic Stem Cell Transplant Patient: A Case Report and Literature Review.  Transplantation Proceedings.  49:373-377. 2017
2017 Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK.  British Journal of Cancer.  116:609-619. 2017
2016 Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.  Carcinogenesis.  37:1052-1061. 2016
2016 MYB promotes desmoplasia in pancreatic cancer through direct transcriptional up-regulation and cooperative action of sonic hedgehog and adrenomedullin.  Journal of Biological Chemistry.  291:16263-16270. 2016
2016 Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer.  Scientific Reports.  6. 2016
2015 Full dose neoadjuvant FOLFIRINOX is associated with prolonged survival in patients with locally advanced pancreatic adenocarcinoma.  Pancreatology.  15:667-673. 2015

Chapter

Year Title Altmetric
2022 Neurological complications of GI cancers.  365-386. 2022
2018 Exosomes: Key supporters of tumor metastasis.  261-283. 2018

Full Name

  • Moh'd Khushman