Nature Communications

Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis..  14:1459. 2023

A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis.  13. 2022

A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes.  13. 2022

ABCA1 is an extracellular phospholipid translocase.  13. 2022

Author Correction: Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways (Nature Communications, (2022), 13, 1, (2669), 10.1038/s41467-022-30342-3).  13. 2022

Creating superconductivity in WB2 through pressure-induced metastable planar defects.  13. 2022

Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C.  13. 2022

Endothelial alpha globin is a nitrite reductase.  13. 2022

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes.  13. 2022

Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.  13. 2022

Global mortality of snakebite envenoming between 1990 and 2019.  13. 2022

Imaging vesicle formation dynamics supports the flexible model of clathrin-mediated endocytosis.  13. 2022

Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms.  13. 2022

Origins of direction selectivity in the primate retina.  13. 2022

Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation.  13. 2022

PCGF6 controls neuroectoderm specification of human pluripotent stem cells by activating SOX2 expression.  13. 2022

Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.  13. 2022

Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.  13. 2022

Restructured membrane contacts rewire organelles for human cytomegalovirus infection.  13. 2022

Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling.  13. 2022

TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer.  13. 2022

TUBB4A interacts with MYH9 to protect the nucleus during cell migration and promotes prostate cancer via GSK3β/β-catenin signalling.  13. 2022

Whole genome sequence analysis of blood lipid levels in >66,000 individuals.  13. 2022

βIV-spectrin as a stalk cell-intrinsic regulator of VEGF signaling.  13. 2022

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma..  13:6041. 2022

A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.  12. 2021

A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.  12. 2021

Antibody neutralization of SARS-CoV-2 through ACE2 receptor mimicry.  12. 2021

Author Correction: Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope (Nature Communications, (2021), 12, 1, (4693), 10.1038/s41467-021-24602-x).  12. 2021

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.  12. 2021

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma.  12. 2021

Genetic determinants of daytime napping and effects on cardiometabolic health.  12. 2021

Genome sequencing unveils a regulatory landscape of platelet reactivity.  12. 2021

Injectable non-leaching tissue-mimetic bottlebrush elastomers as an advanced platform for reconstructive surgery.  12. 2021

Intrathymic differentiation of natural antibody-producing plasma cells in human neonates.  12. 2021

Light quantum control of persisting Higgs modes in iron-based superconductors.  12. 2021

Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis.  12. 2021

SON drives oncogenic RNA splicing in glioblastoma by regulating PTBP1/PTBP2 switching and RBFOX2 activity.  12. 2021

Sam68 promotes hepatic gluconeogenesis via CRTC2.  12. 2021

Shape shifter: redirection of prolate phage capsid assembly by staphylococcal pathogenicity islands.  12. 2021

Structural analysis of cross α-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.  12. 2021

The transcriptional landscape of Shh medulloblastoma.  12. 2021

Toxin secretion and trafficking by Mycobacterium tuberculosis.  12. 2021

Turn-key mapping of cell receptor force orientation and magnitude using a commercial structured illumination microscope.  12. 2021

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level.  12. 2021

Author Correction: Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis (Nature Communications, (2019), 10, 1, (4317), 10.1038/s41467-019-11777-7).  11. 2020

Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y).  11. 2020

Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection (Nature Communications, (2020), 11, 1, (1767), 10.1038/s41467-020-15632-y).  11. 2020

Author Correction: Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption (Nature Communications, (2019), 10, 1, (2700), 10.1038/s41467-019-10563-9).  11. 2020

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis.  11. 2020

Cerebral small vessel disease genomics and its implications across the lifespan.  11. 2020

Circular photogalvanic spectroscopy of Rashba splitting in 2D hybrid organic–inorganic perovskite multiple quantum wells.  11. 2020

Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis.  11. 2020

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner.  11. 2020

Donkey genomes provide new insights into domestication and selection for coat color.  11. 2020

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study.  11. 2020

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease.  11. 2020

Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure.  11. 2020

Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy.  11. 2020

High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.  11. 2020

Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.  11. 2020

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.  11. 2020

Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.  11. 2020

Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection.  11. 2020

Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior.  11. 2020

Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (Nature Communications, (2018), 9, 1, (2606), 10.1038/s41467-018-04668-w).  11. 2020

Publisher Correction: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations (Nature Communications, (2015), 6, 1, (7502), 10.1038/ncomms8502).  11. 2020

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.  11. 2020

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.  11. 2020

Sex differences in oncogenic mutational processes.  11. 2020

Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection.  11. 2020

The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion.  11. 2020

The structures of two archaeal type IV pili illuminate evolutionary relationships.  11. 2020

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae.  11. 2020

α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease.  11. 2020

STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells 2020

Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance..  11:2165. 2020

Microscaled proteogenomic methods for precision oncology..  11:532. 2020

A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions.  10. 2019

AAV2.7m8 is a powerful viral vector for inner ear gene therapy.  10. 2019

Altered chemistry of oxygen and iron under deep Earth conditions.  10. 2019

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.  10. 2019

Associations of autozygosity with a broad range of human phenotypes.  10. 2019

Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis.  10. 2019

Circulating myocardial microRNAs from infarcted hearts are carried in exosomes and mobilise bone marrow progenitor cells.  10. 2019

DNA mechanotechnology reveals that integrin receptors apply pN forces in podosomes on fluid substrates.  10. 2019

Erratum to: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion (Nature Communications, (2018), 9, 1, (3698), 10.1038/s41467-018-05853-7).  10. 2019

Heme and hemoglobin utilization by Mycobacterium tuberculosis.  10. 2019

Interferon lambda protects the female reproductive tract against Zika virus infection.  10. 2019

MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.  10. 2019

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration.  10. 2019

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.  10. 2019

Multi-platform discovery of haplotype-resolved structural variation in human genomes.  10. 2019

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk.  10. 2019

Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers.  10. 2019

Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross.  10. 2019

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease.  10. 2019

Sphingolipid-dependent Dscam sorting regulates axon segregation.  10. 2019

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory.  10. 2019

Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption.  10. 2019

Ultrafast manipulation of topologically enhanced surface transport driven by mid-infrared and terahertz pulses in Bi 2 Se 3.  10. 2019

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes.  10. 2019

Ultrafast manipulation of topologically enhanced surface transport driven by mid-infrared and terahertz pulses in Bi2Se3.  10:607. 2019

B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation..  9:5127. 2018

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.  9. 2018

Biexcitons in monolayer transition metal dichalcogenides tuned by magnetic fields.  9. 2018

Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage (Nature Communications (2018) DOI: 10.1038/s41467-018-03441-3).  9. 2018

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries.  9. 2018

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.  9. 2018

Erratum to: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (Nature Communications, (2018), 9, 1, (2606), 10.1038/s41467-018-04668-w).  9. 2018

Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans.  9. 2018

Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.  9. 2018

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.  9. 2018

Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility.  9. 2018

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.  9. 2018

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer.  9. 2018

Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice.  9. 2018

Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice.  9. 2018

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function.  9. 2018

Network biology discovers pathogen contact points in host protein-protein interactomes.  9. 2018

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.  9. 2018

Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile.  9. 2018

TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.  9. 2018

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.  9. 2018

The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation.  9. 2018

The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation.  9. 2018

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia.  9. 2018

The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma.  9. 2018

Toward a consistent modeling framework to assess multi-sectoral climate impacts.  9. 2018

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.  9. 2018

Valence and spin states of iron are invisible in Earth's lower mantle.  9. 2018

Variability in the location of high frequency oscillations during prolonged intracranial EEG recordings.  9. 2018

Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling..  9:1057. 2018

A 3D magnetic tissue stretcher for remote mechanical control of embryonic stem cell differentiation.  8. 2017

A structural model of flagellar filament switching across multiple bacterial species.  8. 2017

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination.  8. 2017

Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling.  8. 2017

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.  8. 2017

Hyperoxia causes MIR-34a-mediated injury via angiopoietin-1 in neonatal lungs.  8. 2017

Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.  8. 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.  8. 2017

Reducing sarcolipin expression mitigates Duchenne muscular dystrophy and associated cardiomyopathy in mice.  8. 2017

Structural basis for high-affinity actin binding revealed by a β-III-spectrin SCA5 missense mutation.  8. 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.  8:1414. 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.  8. 2017

Ultrafast terahertz snapshots of excitonic Rydberg states and electronic coherence in an organometal halide perovskite.  8. 2017

MiR-29b contributes to multiple types of muscle atrophy.  8. 2017

Iron isotopic fractionation between silicate mantle and metallic core at high pressure.  8. 2017

Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein..  8:14152. 2017

Caloric restriction improves health and survival of rhesus monkeys.  8. 2017

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer.  8. 2017

Oxylipins produced by Pseudomonas aeruginosa promote biofilm formation and virulence.  7. 2016

Reader domain specificity and lysine demethylase-4 family function.  7. 2016

Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability.  7. 2016

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.  7. 2016

PKM2-Dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.  7. 2016

Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.  7. 2016

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis..  7:13205. 2016

MARCH1 regulates insulin sensitivity by controlling cell surface insulin receptor levels.  7. 2016

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.  7. 2016

Mechanosensing by the α 6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.  7. 2016

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself.  7. 2016

Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy.  7. 2016

Regulation of claudin/zonula occludens-1 complexes by hetero-claudin interactions.  7. 2016

Extra-coding RNAs regulate neuronal DNA methylation dynamics.  7. 2016

Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis.  7. 2016

Internal guide RNA interactions interfere with Cas9-mediated cleavage.  7. 2016

Light-activated photocurrent degradation and self-healing in perovskite solar cells.  7. 2016

Low excitatory innervation balances high intrinsic excitability of immature dentate neurons.  7. 2016

Acetylation of C/EBPα inhibits its granulopoietic function.  7. 2016

Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation.  7. 2016

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.  7. 2016

The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis.  7. 2016

Erratum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer (Nature Communications (2014) 5 (4527) DOI: 10.1038/ncomms5527).  7. 2016

Therapeutically engineered induced neural stem cells are tumour-homing and inhibit progression of glioblastoma.  7. 2016

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.  7. 2016

Functional annotation of rare gene aberration drivers of pancreatic cancer.  7. 2016

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.  7. 2016

IL-7 signalling represses Bcl-6 and the T FH gene program.  7. 2016

Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site.  7. 2016

Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex.  6. 2015

TRPC6 specifically interacts with APP to inhibit its cleavage by I 3-secretase and reduce Aβ production.  6. 2015

Late Na + current and protracted electrical recovery are critical determinants of the aging myopathy.  6. 2015

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection.  6. 2015

Real-time fluorescence imaging with 20 nm axial resolution.  6. 2015

Role of T-cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss.  6. 2015

Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.  7. 2015

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.  6. 2015

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.  6. 2015

Dissecting the role of aberrant DNA methylation in human leukaemia.  6. 2015

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE.  6. 2015

Heparanase is a host enzyme required for herpes simplex virus-1 release from cells.  6. 2015

Neural organization of spoken language revealed by lesion-symptom mapping.  6. 2015

The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60.  6. 2015

PD-L1^hi B cells are critical regulators of humoral immunity.  6. 2015

Intracellular CD24 disrupts the ARF-NPM interaction and enables mutational and viral oncogene-mediated p53 inactivation.  6. 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.  6. 2015

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice.  5. 2014

HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance.  5. 2014

Mapping ecologically relevant social behaviours by gene knockout in wild mice.  5. 2014

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.  5. 2014

The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.  5. 2014

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.  5. 2014

IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and RORγt.  5. 2014

Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells.  5. 2014

A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.  5. 2014

Single-vesicle architecture of synaptobrevin2 in astrocytes.  5. 2014

The histone H2A deubiquitinase Usp16 regulates embryonic stem cell gene expression and lineage commitment.  5. 2014

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys.  5. 2014

FoxP3⁺ regulatory T cells promote influenza-specific Tfh responses by controlling IL-2 availability.  5. 2014

Persistent spin excitations in doped antiferromagnets revealed by resonant inelastic light scattering.  5. 2014

Ultrafast observation of critical nematic fluctuations and giant magnetoelastic coupling in iron pnictides.  5. 2014

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.  4. 2013

An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.  4. 2013

Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis.  4. 2013

Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer.  4. 2013

Ultrafast changes in lattice symmetry probed by coherent phonons.  3. 2012

TorsinA participates in endoplasmic reticulum-associated degradation.  2. 2011

Measurement of the inelastic proton-proton cross-section at √s = 7 TeV with the ATLAS detector.  2. 2011