Infection and Immunity

Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung.  19. 2022

A Novel Pneumococcal Surface Protein K of Nonencapsulated Streptococcus pneumoniae Promotes Transmission among Littermates in an Infant Mouse Model with Influenza A Virus Coinfection.  90. 2022

Nontypeable Haemophilus influenzae Infection Impedes Pseudomonas aeruginosa Colonization and Persistence in Mouse Respiratory Tract.  90. 2022

Anatomical Site-Specific Carbohydrate Availability Impacts Streptococcus pneumoniae Virulence and Fitness during Colonization and Disease.  90. 2022

The Glycoprotein 340’s Scavenger Receptor Cysteine-Rich Domain Promotes Adhesion of Staphylococcus aureus and Pseudomonas aeruginosa to Contact Lens Polymers.  90. 2022

The Complex Link between the Female Genital Microbiota, Genital Infections, and Inflammation.  89. 2021

Genetic variation in toll-like receptor 5 and colonization with flagellated bacterial vaginosis-associated bacteria.  89. 2021

Cooperativity between stenotrophomonas maltophilia and pseudomonas aeruginosa during polymicrobial airway infections.  88. 2020

Mosquito bite-induced controlled human malaria infection with Plasmodium vivax or P. Falciparum generates immune responses to homologous and heterologous preerythrocytic and erythrocytic antigens.  87. 2019

Autoinducer 2 (AI-2) production by nontypeable haemophilus influenzae 86-028NP promotes expression of a predicted glycosyltransferase that is a determinant of biofilm maturation, prevention of dispersal, and persistence in vivo.  86. 2018

Role of common γ-Chain cytokines in lung interleukin-22 regulation after acute exposure to aspergillus fumigatus.  86. 2018

Novel immunoprotective proteins of Streptococcus pneumoniae identified by opsonophagocytosis killing screen.  86. 2018

Terminal deoxynucleotidyl transferase is not required for antibody response to polysaccharide vaccines against Streptococcus pneumoniae and Salmonella enterica serovar Typhi.  86. 2018

Acidic mammalian chitinase negatively affects immune responses during acute and chronic Aspergillus fumigatus exposure.  86. 2018

Correction: "Activation of the innate immune system by Treponema denticola periplasmic flagella through Toll-like receptor 2" [Infection and Immunity, 86, 1, e00573-17, (2018)] doi: 10.1128/IAI.00573-17.  86. 2018

Glucan binding protein C of Streptococcus mutans mediates both sucrose-independent and sucrose-dependent adherence.  86. 2018

Activation of the innate immune system by Treponema denticola periplasmic flagella through Toll-like receptor 2.  86. 2018

Cell invasion and pyruvate oxidase-derived H 2 O 2 are critical for Streptococcus pneumoniae-mediated cardiomyocyte killing.  86. 2018

Haemophilus parainfluenzae strain ATCC 33392 forms biofilms in vitro and during experimental otitis media infections.  85. 2017

Phenotype and function of myeloidderived suppressor cells induced by Porphyromonas gingivalis infection.  85. 2017

Position of O-acetylation within the capsular repeat unit impacts the biological properties of pneumococcal serotypes 33A and 33F.  85. 2017

Pneumococcal neuraminidase A (NanA) promotes biofilm formation and synergizes with influenza A virus in nasal colonization and middle ear infection.  85. 2017

Infiltrated macrophages die of pneumolysin-mediated necroptosis following pneumococcal myocardial invasion.  84:1457-1469. 2016

Burkholderia pseudomallei capsule exacerbates respiratory melioidosis but does not afford protection against antimicrobial signaling or bacterial killing in human olfactory ensheathing cells.  84:1941-1956. 2016

Discovery and characterization of human-urine utilization by asymptomaticbacteriuria-causing Streptococcus agalactiae.  84:307-319. 2016

Free sialic acid acts as a signal that promotes streptococcus pneumoniae invasion of nasal tissue and nonhematogenous invasion of the central nervous system.  84:2607-2615. 2016

Neuraminidase A-exposed galactose promotes Streptococcus pneumoniae biofilm formation during colonization.  84:2922-2932. 2016

Accumulation-associated protein enhances Staphylococcus epidermidis biofilm formation under dynamic conditions and is required for infection in a rat catheter model.  83:214-226. 2015

Enterococcus faecalis 6-phosphogluconolactonase is required for both commensal and pathogenic interactions with Manduca sexta.  83:396-404. 2015

Ethanol-induced alcohol dehydrogenase E (AdhE) potentiates pneumolysin in Streptococcus pneumoniae.  83:108-119. 2015

Oral streptococci and nitrite-mediated interference of Pseudomonas aeruginosa.  83:101-107. 2015

Peroxiredoxin-glutaredoxin and catalase promote resistance of nontypeable Haemophilus influenzae 86-028NP to oxidants and survival within neutrophil extracellular traps.  83:239-246. 2015

Requirement for Serratia marcescens cytolysin in a murine model of hemorrhagic pneumonia.  83:614-624. 2015

The omentum is a site of protective IgM production during intracellular bacterial infection.  83:2139-2147. 2015

Extensive variation and rapid shift of the MG192 sequence in Mycoplasma genitalium strains from patients with chronic infection.  82:1326-1334. 2014

Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media.  82:364-370. 2014

Influenza A virus alters pneumococcal nasal colonization and middle ear infection independently of phase variation.  82:4802-4812. 2014

Suppression of antimicrobial peptide expression by Ureaplasma species.  82:1657-1665. 2014

Nanogel-based pspa intranasal vaccine prevents invasive disease and nasal colonization by streptococcus pneumoniae.  81:1625-1634. 2013

Quiescent Innate Response to Infective Filariae by Human Langerhans Cells Suggests aStrategy of Immune Evasion.  81:1420-1429. 2013

Staphylococcus aureus nuclease is an SaeRS-dependent virulence factor.  81:1316-1324. 2013

PspK of Streptococcus pneumoniae increases adherence to epithelial cells and enhances nasopharyngeal colonization.  81:173-181. 2013

Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection.  80:3145-3160. 2012

Microbicidal activity of vascular peroxidase 1 in human plasma via generation of hypochlorous acid.  80:2528-2537. 2012

Pneumococcal gene complex involved in resistance to extracellular oxidative stress.  80:1037-1049. 2012

The vsa shield of mycoplasma pulmonis is antiphagocytic.  80:704-709. 2012

Dectin-1-dependent interleukin-22 contributes to early innate lung defense against aspergillus fumigatus.  80:410-417. 2012

Neutrophils produce interleukin 17A (IL-17A) in a Dectin-1- and IL-23-dependent manner during invasive fungal infection.  79:3966-3977. 2011

Contribution of a Streptococcus mutans antigen expressed by a Salmonella vector vaccine in dendritic cell activation.  79:3792-3800. 2011

Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model.  79:3087-3095. 2011

Erratum: Identification of a simple chemical structure associated with protective human antibodies against multiple pneumococcal serogroups.  79:3472. 2011

New cell surface protein involved in biofilm formation by Streptococcus parasanguinis.  79:3239-3248. 2011

The nasal dendritic cell-targeting Flt3 ligand as a safe adjuvant elicits effective protection against fatal pneumococcal pneumonia.  79:2819-2828. 2011

Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.  79:2440-2450. 2011

Malaria immunoepidemiology in low transmission: Correlation of infecting genotype and immune response to domains of Plasmodium falciparum merozoite surface protein 3.  79:2070-2078. 2011

Nontypeable haemophilus influenzae initiates formation of neutrophil extracellular traps.  79:431-438. 2011

Older adults have a low capacity to opsonize pneumococci due to low igm antibody response to pneumococcal vaccinations.  79:314-320. 2011

Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence.  78:3129-3135. 2010

Importance of CXC chemokine receptor 2 in alveolar neutrophil and exudate macrophage recruitment in response to pneumococcal lung infection.  78:2620-2630. 2010

The proline-rich region of pneumococcal surface proteins A and C contains surface-accessible epitopes common to all pneumococci and elicits antibody-mediated protection against sepsis.  78:2163-2172. 2010

Fusobacterium nucleatum envelope protein FomA is immunogenic and binds to the salivary statherin-derived peptide.  78:1185-1192. 2010

Identification of a simple chemical structure associated with protective human antibodies against multiple pneumococcal serogroups (Infection and Immunity (2009) 77, 8, (3374-3379)).  78:1414. 2010

Comprehensive evaluation of Streptococcus sanguinis cell wall-anchored proteins in early infective endocarditis.  77:4966-4975. 2009

LuxS promotes biofilm maturation and persistence of nontypeable Haemophilus influenzae in vivo via modulation of lipooligosaccharides on the bacterial surface.  77:4081-4091. 2009

Identification of a simple chemical structure associated with protective human antibodies against multiple pneumococcal serogroups.  77:3374-3379. 2009

Antibody to the type 3 capsule facilitates immune adherence of pneumococci to erythrocytes and augments their transfer to macrophages.  77:464-471. 2009

The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection.  77:399-404. 2009

A conserved C-terminal 13-amino-acid motif of Gap1 Is Required for Gap1 Function and Necessary for the Biogenesis of a Serine-Rich Glycoprotein of Streptococcus parasanguinis.  76:5624-5631. 2008

Association of Mycoplasma arthritidis mitogen with lethal toxicity but not with arthritis in mice.  76:4989-4998. 2008

Diminished ICAM-1 expression and impaired pulmonary clearance of nontypeable Haemophilus influenzae in a mouse model of chronic obstructive pulmonary disease/emphysema.  76:4959-4967. 2008

Genome of Mycoplasma arthritidis.  76:4000-4008. 2008

Role of integrin αvβ6 in acute lung injury induced by Pseudomonas aeruginosa.  76:2325-2332. 2008

Streptococcus pneumoniae surface protein PcpA elicits protection against lung infection and fatal sepsis.  76:2767-2776. 2008

Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae.  76:2037-2043. 2008

Lipoteichoic acid is important in innate immune responses to gram-positive bacteria.  76:206-213. 2008

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.  75:5930-5938. 2007

PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation.  75:5877-5885. 2007

Treponema denticola activates mitogen-activated protein kinase signal pathways through toll-like receptor 2.  75:5763-5768. 2007

Antibody-independent, CD4⁺ T-cell-dependent protection against pneumococcal colonization elicited by intranasal immunization with purified pneumococcal proteins.  75:5460-5464. 2007

Genetic basis for the new pneumococcal serotype, 6C.  75:4482-4489. 2007

Biofilms protect Mycoplasma pulmonis cells from lytic effects of complement and gramicidin.  75:3696-3699. 2007

Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophages.  75:4127-4137. 2007

National institute of allergy and infectious diseases bioinformatics resource centers: New assets for pathogen informatics.  75:3212-3219. 2007

The glycan moieties and the N-terminal polypeptide backbone of a fimbria-associated adhesin, Fap1, play distinct roles in the biofilm development of Streptococcus parasanguinis.  75:2181-2188. 2007

Contributions of pneumolysin, pneumococcal surface protein A (PspA), and PspC to pathogenicity of Streptococcus pneumoniae D39 in a mouse model.  75:1843-1851. 2007

Phosplioiylclioline decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media.  75:958-965. 2007

Development of a vaccine against invasive pneumococcal disease based on combinations of virulence proteins of Streptococcus pneumoniae.  75:350-357. 2007

The Bacteroides fragilis toxin binds to a specific intestinal epithelial cell receptor.  74:5382-5390. 2006

Identification of a candidate Streptococcus pneumoniae core genome and regions of diversity correlated with invasive pneumococcal disease.  74:4766-4777. 2006

Cell wall-mediated neuronal damage in early sepsis.  74:3783-3789. 2006

Erratum: β-arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae (Infection and Immunity (2005) 73, 12 (7827-7835)).  74:3078. 2006

How the bacterial pathogen Listeria monocytogenes mediates the switch from environmental Dr. Jekyll to pathogenic Mr. Hyde.  74:2506-2512. 2006

Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS.  74:2809-2816. 2006

Biofilm growth increases phosphorylcholine content and decreases potency of nontypeable Haemophilus influenzae endotoxins.  74:1828-1836. 2006

Mn²⁺-dependent regulation of multiple genes in Streptococcus pneumoniae through PsaR and the resultant impact on virulence.  74:1171-1180. 2006

Multifunctional role of choline binding protein G in pneumococcal pathogenesis.  74:821-829. 2006

β-arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae.  73:7827-7835. 2005

Anti-idiotypic antibody as a potential candidate vaccine for Neisseria meningitidis serogroup B.  73:6399-6406. 2005

Cellular mechanisms of the adjuvant activity of the flagellin component FljB of Salmonella enterica serovar typhimurium to potentiate mucosal and systemic responses.  73:6763-6770. 2005

Enterotoxin-based mucosal adjuvants alter antigen trafficking and induce inflammatory responses in the nasal tract.  73:6892-6902. 2005

Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci.  73:6945-6951. 2005

Role of mitogen-activated protein kinases and NF-κB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin B.  73:3990-3998. 2005

The vaccine candidate Vibrio cholerae 638 is protective against cholera in healthy volunteers..  73:3018-3024. 2005

Avoidance of the host immune system through phase variation in Mycoplasma pulmonis.  73:2033-2039. 2005

Relationship between surface accessibility for PpmA, PsaA, and PspA and antibody-mediated immunity to systemic infection by Streptococcus pneumoniae.  73:1304-1312. 2005

Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage.  73:1006-1013. 2005

Monoacyl lipoteichoic acid from pneumococci stimulates human cells but not mouse cells.  73:834-840. 2005

Association of a major protein antigen of Mycoplasma arthritidis with virulence.  73:245-249. 2005

Bacteriophage MAV1 is not associated with virulence of Mycoplasma arthritidis.  72:7322-7325. 2004

Erratum: PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin (Infection and Immunity (2004) 72, 9 (5031-5040)).  72:7379. 2004

Resistance of Mycoplasma pulmonis to complement lysis is dependent on the number of Vsa tandem repeats: Shield hypothesis.  72:6846-6851. 2004

Lipoprotein PsaA in virulence of Streptococcus pneumoniae: Surface accessibility and role in protection from superoxide.  72:5858-5867. 2004

Microarray analysis of pneumococcal gene expression during invasive disease.  72:5582-5596. 2004

Role of B7 costimulatory molecules in mediating systemic and mucosal antibody responses to attenuated Salmonella enterica serovar typhimurium and its cloned antigen.  72:5824-5831. 2004

PspA protects Streptococcus pneumoniae from killing by apolactoferrin, and antibody to PspA enhances killing of pneumococci by apolactoferrin.  72:5031-5040. 2004

Molecular Characterization of Ancylostoma ceylanicum Kunitz-Type Serine Protease Inhibitor: Evidence for A Role in Hookworm-Associated Growth Delay.  72:2214-2221. 2004

Role of B7 Costimulatory Molecules in Immune Responses and T-Helper Cell Differentiation in Response to Recombinant HagB from Porphyromonas gingivalis.  72:637-644. 2004

Effects of PspA and Antibodies to PspA on Activation and Deposition of Complement on the Pneumococcal Surface.  72:114-122. 2004

Sialylation of Lipooligosaccharides Promotes Biofilm Formation by Nontypeable Haemophilus influenzae.  72:106-113. 2004

Pneumococcal Surface Protein A Is Expressed in Vivo, and Antibodies to PspA Are Effective for Therapy in a Murine Model of Pneumococcal Sepsis.  71:7149-7153. 2003

Pneumococcal lipoteichoic acid (LTA) is not as potent as staphylococcal LTA in stimulating Toll-like receptor 2.  71:5541-5548. 2003

The Vsa proteins modulate susceptibility of Mycoplasma pulmonis to complement killing, hemadsorption, and adherence to polystyrene.  71:5733-5738. 2003

Increased protection against pneumococcal disease by mucosal administration of conjugate vaccine plus interleukin-12.  71:4780-4788. 2003

Relative roles of genetic background and variation in PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae.  71:4498-4505. 2003

Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A.  71:2498-2507. 2003

Effects of zinc deficiency and pneumococcal surface protein A immunization on zinc status and the risk of severe infection in mice.  71:2009-2013. 2003

CD14- and toll-like receptor-dependent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli.  71:1470-1480. 2003

Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model.  71:1033-1041. 2003

Restoration of cytoadherence to an adherence-deficient mutant of Mycoplasma arthritidis by genetic complementation.  71:671-675. 2003

Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.  71:75-85. 2003

Feasibility of an HA2 domain-based periodontitis vaccine.  71:562-566. 2003

Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae.  71:218-225. 2003

Construction of a novel transposon mutagenesis system useful in the isolation of streptococcus parasanguis mutants defective in Fap1 glycosylation.  70:6534-6540. 2002

Effect of trimethoprim-sulfamethoxazole on recurrent bacteriuria and bacterial persistence in mice infected with uropathogenic Escherichia coli.  70:7042-7049. 2002

Enhanced immunogenicity of a genetic chimeric protein consisting of two virulence antigens of Streptococcus mutans and protection against infection.  70:6779-6787. 2002

Susceptibility of nontypeable Haemophilus influenzae to human β-defensins is influenced by lipooligosaccharide acylation.  70:5287-5289. 2002

Acylation of the lipooligosaccharide of Haemophilus influenzae and colonization: An htrB mutation diminishes the colonization of human airway epithelial cells.  70:4661-4668. 2002

Mechanisms of monophosphoryl lipid A augmentation of host responses to recombinant HagB from Porphyromonas gingivalis.  70:3557-3565. 2002

Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains.  70:2512-2518. 2002

Role of pneumococcal surface protein C in nasopharyngeal carriage and pneumonia and its ability to elicit protection against carriage of Streptococcus pneumoniae.  70:2526-2534. 2002

Randomized, controlled human challenge study of the safety, immunogenicity, and protective efficacy of a single dose of Peru-15, a live attenuated oral cholera vaccine.  70:1965-1970. 2002

Type III group B streptococcal polysaccharide induces antibodies that cross-react with Streptococcus pneumoniae type 14.  70:1724-1738. 2002

Identification and characterization of a nonimmunoglobulin factor in human saliva that inhibits Streptococcus mutans glucosyltransferase..  70:1136-1142. 2002

Streptococcus pneumoniae PstS production is phosphate responsive and enhanced during growth in the murine peritoneal cavity.  69:7565-7571. 2001

Effect of attenuated Salmonella enterica serovar Typhimurium expressing a Streptococcus mutans antigen on secondary responses to the cloned protein.  69:6604-6611. 2001

Intranasal vaccination with pneumococcal surface protein A and Interleukin-12 augments antibody-mediated opsonization and protective immunity against Streptococcus pneumoniae infection.  69:6718-6724. 2001

Resistance of T-cell receptor δ-chain-deficient mice to experimental Candida albicans vaginitis.  69:7162-7164. 2001

Urethral cytokine and immune responses in Chlamydia trachomatis-infected males.  69:7178-7181. 2001

Cyclophosphamide decreases nitrotyrosine formation and inhibits nitric oxide production by alveolar macrophages in mycoplasmosis.  69:6401-6410. 2001

Intranasal immunization with killed unencapsulated whole cells prevents colonization and invasive disease by capsulated pneumococci.  69:4870-4873. 2001

Distinct cytokine regulation by cholera toxin and type II heat-labile toxins involves differential regulation of CD40 ligand on CD4⁺ T cells.  69:4486-4492. 2001

Requirement for capsule in colonization by Streptococcus pneumoniae.  69:3755-3761. 2001

Characterization of binding of human lactoferrin to pneumococcal surface protein A.  69:3372-3381. 2001

Monoclonal antibodies specific for Neisseria meningitidis group B polysaccharide and their peptide mimotopes.  69:3335-3342. 2001

Essential role for cellular phosphoglucomutase in virulence of type 3 Streptococcus pneumoniae.  69:2309-2317. 2001

Induction of protective immunity against Streptococcus mutans colonization after mucosal immunization with attenuated Salmonella enterica serovar typhimurium expressing an S. mutans adhesin under the control of in vivo-inducible nirB promoter.  69:2154-2161. 2001

Avidity, potency, and cross-reactivity of monoclonal antibodies to pneumococcal capsular polysaccharide serotype 6B.  69:336-344. 2001

Recombinant antigen-enterotoxin A2/B chimeric mucosal immunogens differentially enhance antibody responses and B7-dependent costimulation of CD4⁺ T cells.  69:252-261. 2001

Differential interleukin-8 response of intestinal epithelial cell line to reactogenic and nonreactogenic candidate vaccine strains of Vibrio cholerae..  69:613-616. 2001

Disease outcome subsequent to primary and secondary urogenital infection with murine or human biovars of Chlamydia trachomatis.  68:7186-7189. 2000

Construction and characterization of a nonproliferative El Tor cholera vaccine candidate derived from strain 638..  68:6411-6418. 2000

Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-associated antigen..  68:5509-5516. 2000

Genetic characterization of a Streptococcus mutans LraI family operon and role in virulence.  68:4441-4451. 2000

Regulation of Brucella abortus catalase.  68:3861-3866. 2000

Immunization of mice with combinations of pneumococcal virulence proteins elicits enhanced protection against challenge with Streptococcus pneumoniae.  68:3028-3033. 2000

Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexes.  68:1441-1449. 2000

Construction and characterization of a Salmonella enterica serovar typhimurium clone expressing a salivary adhesin of Streptococcus mutans under control of the anaerobically inducible nirB promoter.  68:1549-1556. 2000

Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L.  68:511-517. 2000

Construction and characterization of an effector strain of Streptococcus mutans for replacement therapy of dental caries.  68:543-549. 2000

GAA trinucleotide repeat region regulates M9/pMGA gene expression in Mycoplasma gallisepticum.  68:871-876. 2000

Intranasal immunization of mice with a mixture of the pneumococcal proteins PsaA and PspA is highly protective against nasopharyngeal carriage of Streptococcus pneumoniae.  68:796-800. 2000

Adjuvant activity of monophosphoryl lipid A for nasal and oral immunization with soluble or liposome-associated antigen.  68:5509-5516. 2000

Comparative analysis of the mucosal adjuvanticity of the type II heat- labile enterotoxins LT-IIa and LT-IIb.  68:281-287. 2000

Diversity of PspA: Mosaic genes and evidence for past recombination in Streptococcus pneumoniae.  68:5889-5900. 2000

Human C-reactive protein is protective against fatal Salmonella enterica serovar Typhimurium infection in transgenic mice.  68:5652-5656. 2000

Peptide mimic of phosphorylcholine, a dominant epitope found on Streptococcus pneumoniae.  68:5778-5784. 2000

Peritoneal culture alters Streptococcus pneumoniae protein profiles and virulence properties.  68:6082-6086. 2000

Expression of recombinant enterotoxigenic Escherichia coli colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response.  67:6249-6256. 1999

Protective immunity against Streptococcus mutans infection in mice after intranasal immunization with the glucan-binding region of S. mutans glucosyltransferase.  67:6543-6549. 1999

Randomized, double-blind, placebo-controlled, multicentered trial of the efficacy of a single dose of live oral cholera vaccine CVD 103-HgR in preventing cholera following challenge with Vibrio cholerae O1 El Tor Inaba three months after vaccination.  67:6341-6345. 1999

The pspC gene of Streptococcus pneumoniae encodes a polymorphic protein, PspC, which elicits cross-reactive antibodies to PspA and provides immunity to pneumococcal bacteremia.  67:6533-6542. 1999

Validation and characterization of a human volunteer challenge model for cholera by using frozen bacteria of the new Vibrio cholerae epidemic serotype, O139.  67:6346-6349. 1999

Preliminary assessment of the safety and immunogenicity of a new CTXPhi-negative, hemagglutinin/protease-defective El Tor strain as a cholera vaccine candidate..  67:539-545. 1999

A controlled clinical study of the effect of nasal immunization with a Streptococcus mutans antigen alone or incorporated into liposomes on induction of immune responses.  67:618-623. 1999

Alpha-toxin damages the air-blood barrier of the lung in a rat model of Staphylococcus aureus-induced pneumonia.  67:5541-5544. 1999

Erratum: Identification of a Chlamydia trachomatis serovar E urogenital isolate which lacks the cryptic plasmid (Infection and Immunity (1998) 66:12 (6010-6013)).  67:2051. 1999

Functional and immunogenic characterization of two cloned regions of Streptococcus mutans glucosyltransferase I.  67:810-816. 1999

Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model.  67:4352-4359. 1999

Limited local and systemic antibody responses to Neisseria gonorrhoeae during uncomplicated genital infections.  67:3937-3946. 1999

Observed differences in virulence-associated phenotypes between a human clinical isolate and a veterinary isolate of Mycobacterium avium.  67:4895-4901. 1999

Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae.  67:4720-4724. 1999

Prior genital tract infection with a murine or human biovar of Chlamydia trachomatis protects mice against heterotypic challenge infection.  67:3019-3025. 1999

Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B.  67:1172-1179. 1999

Tumor necrosis factor alpha receptor I is important for survival from Streptococcus pneumoniae infections.  67:595-601. 1999

Virulence of a spaP mutant of Streptococcus mutans in a gnotobiotic rat model.  67:1201-1206. 1999

Comparison of the PspA sequence from Streptococcus pneumoniae EF5668 to the previously identified PspA sequence from strain Rx1 and ability of PspA from EF5668 to elicit protection against pneumococci of different capsular types..  66:4748-4754. 1998

A live recombinant avirulent oral Salmonella vaccine expressing pneumococcal surface protein a induces protective responses against Streptococcus pneumoniae.  66:3744-3751. 1998

A protein (M9) associated with monoclonal antibody-mediated agglutination of Mycoplasma gallisepticum is a member of the pMGA family.  66:5570-5575. 1998

Comparison of an adherence domain and a structural region of Streptococcus mutans antigen I/II in protective immunity against dental caries in rats after intranasal immunization..  66:1740-1743. 1998

Cytokine Involvement in Immunomodulatory Activity Affected by Candida albicans Mannan.  66:1384-1391. 1998

Differences in immune responses induced by oral and rectal immunizations with Salmonella typhi Ty21a: Evidence for compartmentalization within the common mucosal immune system in humans.  66:5630-5635. 1998

Differences in the Frequency of Cytokine-Producing Cells in Antigenemic and Nonantigenemic Individuals with Bancroftian Filariasis.  66:1377-1383. 1998

Effect of lipopolysaccharide and inflammatory cytokines on interleukin- 6 production by healthy human gingival fibroblasts.  66:608-614. 1998

Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system.  66:4299-4304. 1998

Enhanced Protective Antibody Responses to PspA after Intranasal or Subcutaneous Injections of PspA Genetically Fused to Granulocyte-Macrophage Colony-Stimulating Factor or Interleukin-2.  66:1513-1520. 1998

Evaluation of immunoglobulin A1 (IgA1) protease and IgA1 protease- inhibitory activity in human female genital infection with Neisseria gonorrhoeae.  66:5826-5832. 1998

Genetic and biochemical analysis of mutacin 1140, a lantibiotic from Streptococcus mutans.  66:2743-2749. 1998

Identification of a Chlamydia trachomatis serovar e urogenital isolate which lacks the cryptic plasmid.  66:6010-6013. 1998

Inactivation of the gbpA gene of Streptococcus mutans increases virulence and promotes in vivo accumulation of recombinations between the glucosyltransferase B and C genes.  66:2180-2185. 1998

Role of tumor necrosis factor alpha in the host response of mice to bacteremia caused by pneumolysin-deficient Streptococcus pneumoniae.  66:839-842. 1998

Susceptibility of epithelial cells to Pseudomonas aeruginosa invasion and cytotoxicity is upregulated by hepatocyte growth factor.  66:3443-3446. 1998

The cysteine-cysteine family of chemokines RANTES, MIP-1α, and MIP-1β induce trypanocidal activity in human macrophages via nitric oxide.  66:4690-4695. 1998

Validation of a volunteer model of cholera with frozen bacteria as the challenge.  66:1968-1972. 1998

Promoter activities in Vibrio cholerae ctx phi prophage..  65:1561-1565. 1997

Avirulence of LT2 strains of Salmonella typhimurium results from a defective rpoS gene.  65:2451-2453. 1997

Depletion of alveolar macrophages exacerbates respiratory mycoplasmosis in mycoplasma-resistant C57BL mice but not mycoplasma-susceptible C3H mice.  65:2278-2282. 1997

Development of a model of low-inoculum Streptococcus pneumoniae intrapulmonary infection in infant rats.  65:4701-4704. 1997

Differences in virulence for mice among Streptococcus pneumoniae strains of capsular types 2, 3, 4, 5, and 6 are not attributable to differences in pneumolysin production.  65:1237-1244. 1997

Effects of Porphyromonas gingivalis and Escherichia coli lipopolysaccharides on mononuclear phagocytes.  65:3248-3254. 1997

Expression of thin aggregative fimbriae promotes interaction of Salmonella typhimurium SR-11 with mouse small intestinal epithelial.  65:5320-5325. 1997

Mucosal immunogenicity of a recombinant Salmonella typhimurium-cloned heterologous antigen in the absence or presence of coexpressed cholera toxin A2 and B subunits.  65:1445-1454. 1997

Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection.  65:640-644. 1997

Characterization of PepB, a group B streptococcal oligopeptidase.  64:3401-3406. 1996

Epitope maps of the Escherichia coli heat-labile toxin B subunit for development of a synthetic oral vaccine.  64:1290-1298. 1996

Helicobacter pylori cytotoxin induces vacuolation of primary human mucosal epithelial cells.  64:4867-4871. 1996

Hyaluronate capsule and surface M protein in resistance to opsonization of group A streptococci.  64:1495-1501. 1996

Persistence of serum and salivary antibody responses after oral immunization with a bacterial protein antigen genetically linked to the A2/B subunits of cholera toxin.  64:665-667. 1996

Phylogenetic distribution of streptococcal superantigen SSA allelic variants provides evidence for horizontal transfer of ssa within Streptococcus pyogenes.  64:1161-1165. 1996

Resistance to mycoplasmal lung disease in mice is a complex genetic trait.  64:5326-5331. 1996

Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae.  64:4850-4853. 1996

Salivary, nasal, genital, and systemic antibody responses in monkeys immunized intranasally with a bacterial protein antigen and the cholera toxin B subunit.  64:1272-1283. 1996

Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars.  64:2839-2841. 1996

The predicted amino acid sequence of the Salmonella typhimurium virulence gene mviA⁺ strongly indicates that MviA is a regulator protein of a previously unknown S. typhimurium response regulator family.  64:2365-2367. 1996

Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus: dose response and induction of protective humoral responses in rats..  63:2004-2011. 1995

A pneumolysin-negative mutant of Streptococcus pneumoniae causes chronic bacteremia rather than acute sepsis in mice.  63:448-455. 1995

Functional capacities of clonal antibodies to Haemophilus influenzae type b polysaccharide.  63:2989-2994. 1995

Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice.  63:2532-2536. 1995

The V-region repertoire of Haemophilus influenzae type b polysaccharide antibodies induced by immunization of infants.  63:4219-4223. 1995

Oral immunization with recombinant Salmonella typhimurium expressing surface protein antigen A of Streptococcus sobrinus: persistence and induction of humoral responses in rats..  62:3162-3171. 1994

Cloning and characterization of a potentially protective chitinase-like recombinant antigen from Wuchereria bancrofti.  62:1901-1908. 1994

Comparison of nonhuman primate antibodies against Haemophilus influenzae type b polysaccharide with human antibodies in oligoclonality and in vivo protective potency.  62:2426-2431. 1994

Effect of genetic switching of capsular type on virulence of Streptococcus pneumoniae.  62:1813-1819. 1994

Functional activity of antibodies to the group B polysaccharide of group B streptococci elicited by a polysaccharide-protein conjugate vaccine.  62:1593-1599. 1994

Molecular characterization and phylogenetic distribution of the streptococcal superantigen gene (ssa) from Streptococcus pyogenes.  62:1867-1874. 1994

Nitric oxide produced during murine listeriosis is protective.  62:1089-1100. 1994

Role of M protein in pharyngeal colonization by group A streptococci in rats..  61:2277-2283. 1993

Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines.  61:48-55. 1993

Comparison of naturally acquired and vaccine-induced antibodies to Haemophilus influenzae type B capsular polysaccharide.  61:5345-5350. 1993

Effects of Escherichia coli and E. coli lipopolysaccharides on the function of human ureteral epithelial cells cultured in serum-free medium.  61:3304-3312. 1993

Enhancing effect of cholera toxin on interleukin-6 secretion by IEC-6 intestinal epithelial cells: Mode of action and augmenting effect of inflammatory cytokines.  61:4637-4644. 1993

Immune response of the female rat genital tract after oral and local immunization with keyhole limpet hemocyanin conjugated to the cholera toxin B subunit.  61:2162-2171. 1993

Interleukin-1 is linked to the respiratory epithelial cytopathology of pertussis.  61:3123-3128. 1993

Lack of complete correlation between emetic and T-cell-stimulatory activities of staphylococcal enterotoxins.  61:3175-3183. 1993

Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant.  61:4272-4279. 1993

Protective salivary immunoglobulin A responses against Streptococcus mutans infection after intranasal immunization with S. mutans antigen I/II coupled to the B subunit of cholera toxin.  61:1964-1971. 1993

Reduction in oral immunogenicity of cholera toxin B subunit by N-terminal peptide addition.  61:384-390. 1993

Cholera toxin as a mucosal adjuvant: Effects of H-2 major histocompatibility complex and lps genes.  60:2874-2879. 1992

Dual roles for class II major histocompatibility complex molecules in staphylococcal enterotoxin-induced cytokine production and in vivo toxicity.  60:5190-5196. 1992

Humoral response to Porphyromonas (Bacteroides) gingivalis in rats: Time course and T-cell dependence.  60:3579-3585. 1992

Mouse antibody to phosphocholine can protect mice from infection with mouse-virulent human isolates of Streptococcus pneumoniae.  60:1957-1962. 1992

Prevention of C3 deposition by capsular polysaccharide is a virulence mechanism of type III group B streptococci.  60:3986-3993. 1992

Serotype diversity and antigen variation among invasive isolates of Ureaplasma urealyticum from neonates.  60:3472-3474. 1992

Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae.  60:111-116. 1992

A 43-kilodalton pneumococcal surface protein, PspA: Isolation, protective abilities, and structural analysis of the amino-terminal sequence.  59:1285-1289. 1991

Mouse hepatitis virus strain UAB infection enhances resistance to Salmonella typhimurium in mice by inducing suppression of bacterial growth.  59:852-856. 1991

PspA, a surface protein of Streptococcus pneumonia, is capable of eliciting protection against pneumococci of more than one capsular type.  59:222-228. 1991

Antibody-secreting peripheral blood lymphocytes induced by immunization with a conjugate consisting of Streptococcus pneumoniae type 12F polysaccharide and diphtheria toxoid.  58:2547-2554. 1990

Activation of cholera toxin-specific T cells in vitro.  58:3711-3716. 1990

Characterization of rat T helper cell clones specific for Bacteroides gingivalis antigen.  58:2785-2791. 1990

Hyperoxia potentiates Ureaplasma urealyticum pneumonia in newborn mice.  58:3487-3493. 1990

Liposomes containing anti-idiotypic antibodies: An oral vaccine to induce protective secretory immune response specific for pathogens of mucosal surfaces.  58:1932-1936. 1990

Pneumococcal surface protein A (PspA) is serologically highly variable and is expressed by all clinically important capsular serotypes of Streptococcus pneumoniae.  58:3293-3299. 1990

Secretory immunoglobulin A carries oligosaccharide receptors for Escherichia coli type 1 fimbrial lectin.  58:3073-3077. 1990

Serum antibody response in adult volunteers elicited by injection of Streptococcus pneumoniae type 12F polysaccharide alone or conjugated to diphtheria toxoid.  58:2309-2312. 1990

Antipneumococcal effects of C-reactive protein and monoclonal antibodies to pneumococcal cell wall and capsular antigens.  57:1457-1464. 1989

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae.  57:2037-2042. 1989

Subunit structure of the variable V-1 antigen of Mycoplasma pulmonis.  57:1684-1690. 1989

Ureaplasma urealyticum pneumonia: Experimental production and demonstration of age-related susceptibility.  57:918-925. 1989

A pneumococcal surface protein (PspB) that exhibits the same protease sensitivity as streptococcal R antigen.  56:3001-3003. 1988

Analysis of the virulence of Streptococcus mutans serotype c gtfA mutants in the rat model system.  56:322-330. 1988

Fungal-strain-dependent alterations in the time course and mortality of chronic murine pulmonary blastomycosis.  56:34-39. 1988

Plasmid-containing strains of Streptococcus mutans cluster within family and racial cohorts: Implications for natural transmission.  56:3216-3220. 1988

Human immunoglobulin G antibody response to the major gonococcal iron-regulated protein.  55:3065-3069. 1987

Association and dissociation of Escherichia coli heat-stable enterotoxin from rat brush border membrane receptors.  55:329-334. 1987

Protection of gnotobiotic rats against dental caries by passive immunization with bovine milk antibodies to Streptocococcus mutans.  55:2341-2347. 1987

Protein variability among strains of Mycoplasma pulmonis.  55:2838-2840. 1987

Characterization of immune response to oral administration of Streptococcus sobrinus ribosomal preparations in liposomes.  54:780-786. 1986

Detection and specificity of antibodies secreted by spleen cells in mice immunized with Streptococcus mutans.  53:317-323. 1986

Plasmid-determined cytotoxicity in Yersinia pestis and Yersinia pseudotuberculosis.  51:788-794. 1986

Salivary immunoglobulin A and serum antibodies to Streptococcus mutans ribosomal preparations in dental caries-free and caries-susceptible human subjects.  51:348-351. 1986

Salmonella typhimurium virulence genes necessary to exploit the Ity(s/s) genotype of the mouse.  51:872-878. 1986

Bacterial lipopolysaccharide induction of leukocyte-derived corticotropin and endorphins.  48:813-817. 1985

Comparative bacteriology of juvenile periodontitis.  48:507-519. 1985

Distinct bacteriocin groups correlate with different groups of Streptococcus mutans plasmids.  48:51-56. 1985

Immunoglobulin A subclass distribution of naturally occurring salivary antibodies to microbial antigens.  49:459-462. 1985

Inhibition of plaque and caries formation by a glucan produced by Streptococcus mutans mutant UAB108.  50:833-843. 1985

Serum antibody reactive with predominant organisms in the subgingival flora of young adults with generalized severe periodontitis.  48:303-311. 1985

The ability of Salmonella typhimurium to produce the siderophore enterobactin is not a virulence factor in mouse typhoid.  50:392-397. 1985

Analysis of the antigen specificity of the human serum immunoglobulin G immune response to complicated gonococcal infection..  43:706-709. 1984

Bacteriology of experimental gingivitis in children.  46:1-6. 1984

Function of anti-Streptococcus mutans antibodies: Anti-ribosomal antibodies inhibit acid production, growth, and glucose phosphotransferase activity.  45:286-289. 1984

Lack of cross-reactivity of antibodies to ribosomal preparations from Streptococcus mutans with human heart and kidney antigens.  46:42-47. 1984

Variation in periodontal floras.  46:720-726. 1984

Effective immunity to dental caries: Enhancement of salivary anti-Streptococcus mutans antibody responses with oral adjuvants.  40:577-591. 1983

Effective immunity to dental caries: Gastric intubation of Streptococcus mutans whole cells or cell walls induces protective immunity in gnotobiotic rats.  39:645-654. 1983

Immunoglobulin A-mediated hepatobiliary transport constitutes an natural pathway for disposing of bacterial antigens.  42:1041-1048. 1983

In vitro and in vivo complementation of Streptococcus mutans mutants defective in adherence.  42:558-566. 1983

Role of monocytes in polyclonal immunoglobulin production stimulated by sonicates of periodontally associated bacteria.  42:853-862. 1983

Transformed and normal cell surface glycoproteins that induce interferon production by nonsensitized lymphocytes.  39:220-224. 1983

Antigenic analysis of Giardia lamblia from Afghanistan, Puerto Rico, Ecuador, and Oregon.  36:714-719. 1982

Bacteriology of experimental gingivitis in young adult humans.  38:651-667. 1982

Immunization of mice by intracutaneous inoculation with viable virulent Cryptococcus neoformans: Immunological and histopathological parameters.  35:685-696. 1982

Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody.  36:184-188. 1982

Analysis of human anti-diphtheria antibodies by isoelectric focusing: Evidence for restricted clonal heterogeneity of anti-fragment A antibodies.  31:1132-1137. 1981

Cell-produced viral inhibitor: Possible mechanism of action and chemical composition.  32:454-457. 1981

Human B lymphocytes produce leukocyte interferon after interaction with foreign cells.  32:508-512. 1981

Interference of secretory immunoglobulin A with sorption of oral bacteria to hydroxyapatite.  31:942-951. 1981

Oral ecology and virulence of Lactobacillus casei and Streptococcus mutans in gnotobiotic rats.  33:690-696. 1981

Phagocytosis and killing of Salmonella typhimurium by peritoneal exudate cells.  33:380-388. 1981

Polyclonal B-cell activation induced by extracts of gram-negative bacteria isolated from periodontally diseased sites.  34:43-49. 1981

Specific lymphocyte blastogenic responses in children with cytomegalovirus and herpes simplex virus infections acquired early in infancy.  34:166-170. 1981

Virulence of Streptococcus mutans: Characterization of a serotype g antigen-defective mutant and its revertants.  31:151-159. 1981

Effects of cyclophosphamide on murine candidiasis.  27:376-386. 1980

Experimental murine candidiasis: cell-mediated immunity after cutaneous challenge.  27:140-149. 1980

Interferon immunosuppression: Mediation by a suppressor factor.  29:301-305. 1980

Modification of bacterial serum susceptibility by rifampin.  28:923-926. 1980

Transfer of interferon-induced viral resistance from human leukocytes to other cell types.  29:356-360. 1980

Virulence of Streptococcus mutans: Immunochemical characterization of a serotype g-defective mutant (C307).  27:697-699. 1980

Virulence of Streptococcus mutans: In vivo reversion of a low-virulence mutant results in partial displacement and pathogenesis.  27:1003-1011. 1980

Virulence of Streptococcus mutans: Restoration of pathogenesis of a glucosyltransferase-defective mutant (C4).  27:915-921. 1980

Cellular interactions determine the rate and degree of interferon action.  23:496-501. 1979

Pathogenic species of the genus Haemophilus and Streptococcus pneumoniae produce immunoglobulin A1 protease.  26:143-149. 1979

Effective immunity to dental caries: dose-dependent studies of secretory immunity by oral administration of Streptococcus mutans to rats.  19:217-224. 1978

Experimental murine candidiasis: Pathological and immune responses in T-lymphocyte-depleted mice.  21:729-737. 1978

Experimental murine candidiasis: cell-mediated immunity after cutaneous challenge.  20:88-98. 1978

Isolation of glycopeptides with skin test activity from dermatophytes..  19:1031-1046. 1978

Leukocytic endogenous mediator in Crohn's disease.  22:637-639. 1978

Virulence of Streptococcus mutans: Comparison of the effects of a coupling sugar and sucrose on certain metabolic activities and cariogenicity.  19:477-480. 1978

Effective immunity to dental caries: passive transfer to rats of antibodies to Streptococcus mutans elicits protection.  17:644-650. 1977

Low sucrose levels promote extensive Streptococcus mutans induced dental caries.  16:712-714. 1977

Virulence of Streptococcus mutans: cariogenicity of S. mutans in adult gnotobiotic rats.  15:466-471. 1977

Effective immunity to dental caries: protection of malnourished rats by local injection of Streptococcus mutans.  13:782-789. 1976

Naturally occurring secretory immunoglobulin A antibodies to Streptococcus mutans in human colostrum and saliva.  14:355-362. 1976

Effect of Tween 80 and Aquasol A on virus plaque formation.  12:490-494. 1975

Virulence of Streptococcus mutans: a sensitive method for evaluating cariogenicity in young gnotobiotic rats.  12:69-75. 1975

Role of the vegetation in experimental Streptococcus viridans endocarditis.  10:1433-1438. 1974

Interaction of virulent and avirulent Listeria monocytogenes with cultured mouse peritoneal macrophages..  7:409-415. 1973

Bactericidal antibody response in the Pacific hagfish, Eptatretus stoutii..  4:160-166. 1971