Human Pathology

Reprint of: Updates in 2022 on the staging of testicular germ cell tumors. 2023

Molecular characterization of visible low-grade dysplastic lesions in patients with inflammatory bowel disease. 2023

Characterization of protein S-(2-succino)-cysteine (2SC) succination as a biomarker for fumarate hydratase–deficient renal cell carcinoma 2023

Updates in 2022 on the staging of testicular germ cell tumors.  128:152-160. 2022

Aberrant expression of lymphoid enhancer–binding factor 1 in Hodgkin lymphoma.  125:2-10. 2022

Epithelioid osteoblastoma. Clinicopathologic and immunohistochemical study of 17 cases.  125:68-78. 2022

Clinicopathological features of and neoadjuvant therapy for human epidermal growth factor receptor 2-positive classic invasive lobular carcinoma.  117:51-59. 2021

Inhibin-positive hepatic carcinoma: proposal for a solid-tubulocystic variant of intrahepatic cholangiocarcinoma.  116:82-93. 2021

Well-differentiated neuroendocrine tumors of the lower urinary tract: biologic behavior of a rare entity.  109:53-58. 2021

Comparison of three FDA-approved diagnostic immunohistochemistry assays of PD-L1 in triple-negative breast carcinoma..  108:42-50. 2021

Immunohistochemical staining patterns of Ki-67 and p53 in florid reactive urothelial atypia and urothelial carcinoma in situ demonstrate significant overlap.  98:81-88. 2020

Morphology, p16, HPV, and outcomes in squamous cell carcinoma of the penis: a multi-institutional study.  96:79-86. 2020

Recurrent genetic alterations and biomarker expression in primary and metastatic squamous cell carcinomas of the vulva.  92:67-80. 2019

Synchronous and metachronous bilateral breast cancer: clinicopathologic characteristics and prognostic outcomes.  92:1-9. 2019

Clear cell papillary renal cell carcinoma: molecular profile and virtual karyotype.  91:52-60. 2019

PD-L1 expression in non–small cell lung cancer: evaluation of the diagnostic accuracy of a laboratory-developed test using clone E1L3N in comparison with 22C3 and SP263 assays.  90:54-59. 2019

PTEN and ERG detection in multiparametric magnetic resonance imaging/ultrasound fusion targeted prostate biopsy compared to systematic biopsy.  90:20-26. 2019

Tumor immune microenvironment in non–muscle-invasive urothelial carcinoma of the bladder.  89:24-32. 2019

MDM2 amplification and immunohistochemical expression in sarcomatoid renal cell carcinoma.  87:28-36. 2019

Tubulopapillary adrenocortical adenoma in a patient with familial adenomatous polyposis: a morphologic, ultrastructural, and molecular study.  87:51-56. 2019

Management of patients with renal mass lesions based on renal biopsy cytology results..  85:270-278. 2019

Targeted sequencing of plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations.  85:1-9. 2019

Histologic findings associated with false-positive multiparametric magnetic resonance imaging performed for prostate cancer detection.  83:159-165. 2019

SWI/SNF protein expression status in fumarate hydratase–deficient renal cell carcinoma: immunohistochemical analysis of 32 tumors from 28 patients.  77:139-146. 2018

Defining the optimal method for reporting prostate cancer grade and tumor extent on magnetic resonance/ultrasound fusion–targeted biopsies.  76:68-75. 2018

Pathologic and clinical characteristics of early onset renal cell carcinoma.  74:25-31. 2018

Prognostic outcomes in advanced breast cancer: the metastasis-free interval is important.  70:70-76. 2017

Clinical and pathological factors related to brain relapse-free survival in breast cancer patients—reply.  69:142. 2017

Corrigendum to “Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone” (Human Pathology (2017) 65 (239–246) (S0046817717301727) (10.1016/j.humpath.2017.05.015)).  69:143. 2017

The CD4/CD8 ratio of tumor-infiltrating lymphocytes at the tumor-host interface has prognostic value in triple-negative breast cancer.  69:110-117. 2017

MicroRNAs, promising biomarkers in the diagnosis of Xp11 translocation RCC—reply.  68:206-207. 2017

MicroRNA expression profiling of Xp11 renal cell carcinoma.  67:18-29. 2017

Perineural invasion by prostate cancer on MR/US fusion targeted biopsy is associated with extraprostatic extension and early biochemical recurrence after radical prostatectomy.  66:206-211. 2017

Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone.  65:239-246. 2017

Clinicopathological factors associated with survival in patients with breast cancer brain metastasis.  64:53-60. 2017

GATA3 immunohistochemistry in urothelial carcinoma of the upper urinary tract as a urothelial marker and a prognosticator.  64:83-90. 2017

Immune-checkpoint status in penile squamous cell carcinoma: a North American cohort.  59:55-61. 2017

High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors.  54:106-112. 2016

The utility of STAT6 and ALDH1 expression in the differential diagnosis of solitary fibrous tumor versus prostate-specific stromal neoplasms.  54:184-188. 2016

Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder.  53:8-13. 2016

Microvascular injury in persistent gastric ulcers after yttrium-90 microsphere radioembolization for liver malignancies.  50:11-14. 2016

Significance of a minor high-grade component in a low-grade noninvasive papillary urothelial carcinoma of bladder.  47:20-25. 2016

Renal carcinoma associated with a novel succinate dehydrogenase A mutation: A case report and review of literature of a rare subtype of renal carcinoma.  46:1951-1955. 2015

Characterization of estrogen receptor-negative/progesterone receptor-positive breast cancer.  46:1776-1784. 2015

Sinonasal renal cell-like adenocarcinomas: Robust carbonic anhydrase expression.  46:1598-1606. 2015

Granulomatous and lymphocytic interstitial lung disease: A spectrum of pulmonary histopathologic lesions in common variable immunodeficiency - Histologic and immunohistochemical analyses of 16 cases.  46:1306-1314. 2015

Smooth muscle and adenoma-like renal tumor: A previously unreported variant of mixed epithelial stromal tumor or a distinctive renal neoplasm?.  46:894-905. 2015

Immunohistochemical expression of ARID1A in penile squamous cell carcinomas: A tissue microarray study of 112 cases.  46:761-766. 2015

Human papillomavirus infection and immunohistochemical p16^INK4a expression as predictors of outcome in penile squamous cell carcinomas.  46:532-540. 2015

Utility of uroplakin II expression as a marker of urothelial carcinoma.  46:58-64. 2015

ARID1A immunohistochemistry improves outcome prediction in invasive urothelial carcinoma of urinary bladder.  45:2233-2239. 2014

African Americans with oropharyngeal carcinoma have significantly poorer outcomes despite similar rates of human papillomavirus-mediated carcinogenesis.  45:310-319. 2014

Comprehensive profile of GATA binding protein 3 immunohistochemical expression in primary and metastatic renal neoplasms.  45:244-248. 2014

Changing prognostic factors in osteosarcoma: Analysis of 381 cases from two institutions.  45:1688-1696. 2014

Clear cell papillary renal cell carcinoma: Micro-RNA expression profiling and comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma.  45:1130-1138. 2014

GATA3 expression in small cell carcinoma of bladder and prostate and its potential role in determining primary tumor origin.  45:1682-1687. 2014

Dysregulation of mammalian target of rapamycin pathway in upper tract urothelial carcinoma.  44:2668-2676. 2013

Immunohistochemical profile of the penile urethra and differential expression of GATA3 in urothelial versus squamous cell carcinomas of the penile urethra.  44:2760-2767. 2013

The epidermal growth factor receptor is frequently overexpressed in penile squamous cell carcinomas: A tissue microarray and digital image analysis study of 112 cases.  44:2690-2695. 2013

The role of GATA binding protein 3 in the differential diagnosis of collecting duct and upper tract urothelial carcinomas.  44:2651-2657. 2013

Dysregulation of the mammalian target of rapamycin pathway in chromophobe renal cell carcinomas.  44:2323-2330. 2013

Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma.  44:2071-2074. 2013

Relevance of the mammalian target of rapamycin pathway in the prognosis of patients with high-risk non-muscle invasive bladder cancer.  44:1766-1772. 2013

Immunohistochemical expression of SALL4 in hepatocellular carcinoma, a potential pitfall in the differential diagnosis of yolk sac tumors.  44:1293-1299. 2013

Intestinal γδ T-cell lymphomas are most frequently of type II enteropathy-associated T-cell type.  44:1131-1145. 2013

Dysregulation of mammalian target of rapamycin pathway in plasmacytoid variant of urothelial carcinoma of the urinary bladder.  44:612-622. 2013

Expression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression.  44:374-387. 2013

Immunoexpression status and prognostic value of mammalian target of rapamycin and hypoxia-induced pathway members in papillary cell renal cell carcinomas.  43:2129-2137. 2012

GATA binding protein 3 is down-regulated in bladder cancer yet strong expression is an independent predictor of poor prognosis in invasive tumor.  43:2033-2040. 2012

Immunohistochemical expression of minichromosome maintenance complex protein 2 predicts biochemical recurrence in prostate cancer: A tissue microarray and digital imaging analysis-based study of 428 cases.  43:1852-1865. 2012

High epidermal growth factor receptor immunohistochemical expression in urothelial carcinoma of the bladder is not associated with EGFR mutations in exons 19 and 21: A study using formalin-fixed, paraffin-embedded archival tissues.  43:1590-1595. 2012

Distribution and characterization of subtypes of penile intraepithelial neoplasia and their association with invasive carcinomas: A pathological study of 139 lesions in 121 patients.  43:1020-1027. 2012

Factors associated with residual disease after initial breast-conserving surgery for ductal carcinoma in situ.  43:986-993. 2012

Thyroid transcription factor 1 expression in a case of renal collecting duct carcinoma - Reply.  43:1154. 2012

A novel t(6;13)(q15;q34) translocation in a giant cell reparative granuloma (solid aneurysmal bone cyst).  43:952-957. 2012

Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver.  43:695-701. 2012

Ki-67 proliferative index predicts progression-free survival of patients with well-differentiated ileal neuroendocrine tumors.  43:489-495. 2012

Characteristics of positive surgical margins in robotic-assisted radical prostatectomy, open retropubic radical prostatectomy, and laparoscopic radical prostatectomy: A comparative histopathologic study from a single academic center.  43:254-260. 2012

Complex analysis of a recurrent pleomorphic hyalinizing angiectatic tumor of soft parts.  43:121-126. 2012

High-grade papillary urothelial carcinoma of the urinary tract: A clinicopathologic analysis of a post-World Health Organization/International Society of Urological Pathology classification cohort from a single academic center.  43:115-120. 2012

Hepatocyte nuclear factor-1β expression in clear cell adenocarcinomas of the bladder and urethra: Diagnostic utility and implications for histogenesis.  42:1613-1619. 2011

Papillary urothelial neoplasm of low malignant potential of the urinary bladder: clinicopathologic and outcome analysis from a single academic center.  42:1799-1803. 2011

EGFR and KRAS mutations in metastatic lung adenocarcinomas.  42:1447-1453. 2011

S-100P, von Hippel-Lindau gene product, and IMP3 serve as a useful immunohistochemical panel in the diagnosis of adenocarcinoma on endoscopic bile duct biopsy - Reply.  42:1368-1369. 2011

Adrenal lymphangioma: Clinicopathologic and immunohistochemical characteristics of a rare lesion.  42:1013-1018. 2011

Expression of vitamin D receptor decreases during progression of pigmented skin lesions.  42:618-631. 2011

Toluene optic neurotoxicity: Magnetic resonance imaging and pathologic features.  42:295-298. 2011

Pathology graduate medical education (overview from 2006-2010).  42:763-769. 2011

Merkel cell carcinoma: Correlation of KIT expression with survival and evaluation of KIT gene mutational status.  41:1405-1412. 2010

S100P, von Hippel-Lindau gene product, and IMP3 serve as a useful immunohistochemical panel in the diagnosis of adenocarcinoma on endoscopic bile duct biopsy.  41:1210-1219. 2010

Oncogenic BRAF-positive dysplastic nevi and the tumor suppressor IGFBP7-challenging the concept of dysplastic nevi as precursor lesions?.  41:886-894. 2010

Use of immunohistochemistry for IgG4 in the distinction of autoimmune pancreatitis from peritumoral pancreatitis.  41:643-652. 2010

Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology.  40:924-933. 2009

Juvenile juxtacortical chondromyxoid fibroma of bone: a case report.  39:960-965. 2008

Prostatic adenocarcinoma in colorectal biopsy: clinical and pathologic features.  39:543-549. 2008

Colorectal adenocarcinoma involving the prostate: report of 9 cases.  38:1836-1841. 2007

Curriculum content and evaluation of resident competency in clinical pathology (laboratory medicine): a proposal.  37:934-968. 2006

Pathology graduate medical education (overview from 1926 to 2005).  37:923-928. 2006

Recommendations for the reporting of bone tumors.  35:1173-1178. 2004

Expression of CEA, Tag-72, and Lewis-Y Antigen in Primary and Metastatic Lesions of Ovarian Carcinoma.  34:1016-1021. 2003

Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud's syndrome: A case report emphasizing the cytological and cytogenetic findings.  34:1354-1357. 2003

Threshold for Diagnosing Prostate Cancer over Time.  34:1116-1118. 2003

Competency-based residency training in pathology: Challenges and opportunities.  33:3-6. 2002

Altered global methylation of DNA: An epigenetic difference in susceptibility for lung cancer is associated with its progression.  32:856-862. 2001

Trends in pathology graduate medical education.  32:671-676. 2001

A prospective trial of telepathology for intraoperative consultation (frozen sections).  31:781-785. 2000

The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung.  31:482-487. 2000

The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung.  31:1068-1073. 2000

Demonstrability of the glycoprotein A-80 in postradiation prostatic carcinoma.  30:1474-1478. 1999

Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients.  30:208-215. 1999

Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma.  27:1021-1024. 1996

Adenovirus myocarditis: Retrospective diagnosis by gene amplification from formalin-fixed, paraffin-embedded tissues.  25:831-834. 1994

Growth factors in monoclonal light-chain-related renal diseases.  25:883-892. 1994

Induction of proliferating cell nuclear antigen in differentiated keratinocytes of human papillomavirus-infected lesions.  25:343-348. 1994

Reply.  25:1375-1376. 1994

Human papillomavirus type 16 and 18 gene expression in cervical neoplasias.  23:117-128. 1992

Intestinal microsporidiosis as a cause of diarrhea in HIV-infected patients: A report of 20 cases.  21:475-81. 1990

Intestinal microsporidiosis as a cause of diarrhea in human immunodeficiency virus-infected patients: A report of 20 cases.  21:475-481. 1990

The diagnosis of Wegener's granulomatosis from transbronchial biopsy specimens.  21:838-842. 1990

Uterine herpes virus infection with multifocal necrotizing endometritis.  20:1021-1024. 1989

Amiodarone lung: Pathologic finding in clinically toxic patients.  18:349-354. 1987

Myocardial ischemia and infarction: Anatomic and biochemical substrates for ischemic cell death and ventricular arrhythmias.  18:462-475. 1987

Stromal proliferations of the breast: An ultrastructural and immunohistochemical evaluation of cystosarcoma phyllodes, juvenile fibroadenoma, and fibroadenoma.  18:45-49. 1987

Black thyroid: Clinical manifestations, ultrastructural findings, and possible mechanisms.  16:72-78. 1985

Small cell carcinoma of the esophagus: Evidence for a unified histogenesis.  15:460-468. 1984

Why physicians don't pursue abnormal laboratory tests: An investigation of hypercalcemia and the follow-up of abnormal test results.  15:75-78. 1984

Villous polyps of the urethra: A report of two cases.  10:478-481. 1979