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Alpha cell TXNIP deletion improves diabetes-associated hyperglycemia and hyperglucagonemia.
Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes
Retraction: Mechanisms of hemorrhage-induced hepatic insulin resistance: Role of tumor necrosis factor-α (Endocrinology (2004) 145:11 (5168-5176) DOI: 10.1210/en.2004-0524)
Human Glucagon Expression Is under the Control of miR-320a
Human Glucagon Expression Is under the Control of miR-320a.
Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ
Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ.
Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ.
Glucagon-receptor signaling reverses hepatic steatosis independent of leptin receptor expression
Prolactin receptor signaling regulates a pregnancy-specific transcriptional program in mouse islets
G Protein-Coupled Estrogen Receptor Is Not Required for Sex Determination or Ovary Function in Zebrafish
How UV Light Touches the Brain and Endocrine System Through Skin, and Why
Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish
Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: A potential role for fibroblast growth factor-21
Subdomain 2, not the transmembrane domain, determines the dimerization partner of growth hormone receptor and prolactin receptor
Insulin, IGF-1, and GH receptors are altered in an adipose tissue depot-specific manner in male mice with modified GH action
LDB1 regulates energy homeostasis during diet-induced obesity
Brown adipose tissue function is enhanced in long-lived, male ames dwarf mice
Effect of n-3 and n-6 polyunsaturated fatty acids on microsomal P450 steroidogenic enzyme activities and in vitro cortisol production in adrenal tissue from yorkshire boars
-acetyl-5-methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects
Skin under the sun: When melanin pigment meets vitamin D
Evidence of contribution of iPLA
β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA
β in T1D development
Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells
High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit
Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: Involvement of cAMP/PKA signaling
Liver-Specific gh receptor gene-Disrupted (lighrko) mice have decreased endocrine igf-I, increased local igf-I, and altered body size, body composition, and adipokine profiles
Glucocorticoid-dependent hippocampal transcriptome in male rats: Pathway-specific alterations with aging
Hepatic growth hormone resistance after acute injury
Hormonal contraception and hiv-1 infection: Medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms
Central depletion of brain-derived neurotrophic,factorin mice results in high bone mass and metabolic phenotype
Acylation type determines Ghrelin's effects on energy homeostasis in rodents
AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol
Growth hormone-induced JAK2 signaling and GH receptor down-regulation: Role of GH receptor intracellular domain tyrosine residues
Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB
An irradiation-altered bone marrow microenvironment impacts anabolic actions of PTH
Inhibitory GH receptor extracellular domain monoclonal antibodies: Three-dimensional epitope mapping
Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance
Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice
Erratum: Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102)
Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: Roles for AMP-activated protein kinase, Akt, and FOXO1
Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin
Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice.
Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury
Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D
Protein kinase C-ζ phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: Isoform specific determinants of specificity in insulin signaling
Trauma and hemorrhage-induced acute hepatic insulin resistance: Dominant role of tumor necrosis factor-α
Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-γ agonist treatment occurs independently of changes in myocardial insulin signaling
Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells
Genistein attenuates the hypertensive effects of dietary NaCl in hypertensive male rats
Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoter
Identification of the glomerular podocyte as a target for growth hormone action
Role of microsomal retinol/sterol dehydrogenase-like short-chain dehydrogenases/reductases in the oxidation and epimerization of 3α-hydroxysteroids in human tissues
Growth hormone, insulin-like growth factor I, and growth: Local knowledge
Insulin-like growth factor-I stimulates histone H3 and H4 acetylation in the brain in vivo
Janus kinase 2 influences growth hormone receptor metalloproteolysis
Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and Obesity
Cells of the osteoclast lineage as mediators of the anabolic actions of parathyroid hormone in bone
Janus kinase 2 enhances the stability of the mature growth hormone receptor
Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span
Blockade of rapid versus prolonged extracellularly regulated kinase 1/2 activation has differential effects on insulin-induced gene expression
Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces β-cell apoptosis
Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice
Preservation of eumelanin hair pigmentation in proopiomelanocortin- deficient mice on a nonagouti (a/a) genetic background
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor I/insulin signaling and caloric restriction
Growth hormone alters epidermal growth factor receptor binding affinity via activation of extracellular signal-regulated kinases in 3T3-F442A cells
Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis
Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: Microarray deoxyribonucleic acid-chip analysis of gene expression
Differential Expression of a Cutaneous Corticotropin-Releasing Hormone System
Mechanisms of hemorrhage-induced hepatic insulin resistance: Role of tumor necrosis factor-α
Insulin-Regulated Expression of Egr-1 and Krox20: Dependence on ERK1/2 and Interaction with p38 and PI3-Kinase Pathways
Osteoclast Apoptosis: The Role of Fas in Vivo and in Vitro
The role of calmodulin in the regulation of osteoclastogenesis
Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D
in the intestine and kidney of mice
Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: Interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway
Ovine placental lactogen-induced heterodimerization of ovine growth hormone and prolactin receptors in living cells is demonstrated by fluorescence resonance energy transfer microscopy and leads to prolonged phosphorylation of signal transducer and activator of transcription (STAT)1 and STAT3
A role for Grb2-associated binder-1 in growth hormone signaling
Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function
Oligonucleotide microarray analysis of intact human pancreatic islets: Identification of glucose-responsive genes and a highly regulated TGFβ signaling pathway
Impairment of Liver GH Receptor Signaling by Fasting.
A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets
Impairment of liver GH receptor signaling by fasting
Minireview: Receptor Dimerization in GH and Erythropoietin Action-It Takes Two to Tango, But How?
Minireview: Receptor dimerization in GH and erythropoietin action - It takes two to Tango, but how?
White adipocyte vascular endothelial growth factor: Regulation by insulin
Inhibition of central amylin signaling increases food intake and body adiposity in rats
Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype
Divergent Immune Responses in Male and Female Mice after Trauma-Hemorrhage: Dimorphic Alterations in T Lymphocyte Steroidogenic Enzyme Activities.
Immediate and prolonged patterns of Agouti-related peptide-(83--132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites.
Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid- treated rabbits.
Differential regulation of the two principal Runx2/Cbfa1 N-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype
Divergent immune responses in male and female mice after trauma-hemorrhage: Dimorphic alterations in T lymphocyte steroidogenic enzyme activities
Immediate and prolonged patterns of Agouti-related peptide-(83-132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites
Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: Relationship to GH receptor down-regulation
Receptor activator of nuclear factor-κB ligand activates nuclear factor-κB in osteoclast precursors
Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid-treated rabbits
Amylin: A novel action in the brain to reduce body weight
Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation.
Amylin: a novel action in the brain to reduce body weight.
Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation
Tumor necrosis factor α regulates α
integrin expression by osteoclast precursors in vitro and in vivo
Tumor necrosis factor-α converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: The metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation
Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione.
Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells
Insulin receptor substrate-1 enhances growth hormone-induced proliferation
Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: Decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione
Mass Spectrometric Evidence That Agents That Cause Loss of Ca2+ from Intracellular Compartments Induce Hydrolysis of Arachidonic Acid from Pancreatic Islet Membrane Phospholipids by a Mechanism That Does Not Require a Rise in Cytosolic Ca2+ Concentration* * This work was supported by U.S. Public Health Service grants PO1-HL57278, P41-RR-00954, and S10-RR-11260 and by an American Diabetes Association Career Development Award (S.R.).
Blockade of growth hormone receptor shedding by a metalloprotease inhibitor
Mass spectrometric evidence that agents that cause loss of Ca
from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca
Expression and Subcellular Distribution of the β-Isoform of the Human Glucocorticoid Receptor.
A role for phospholipase C activity in GLUT4-mediated glucose transport
Fatty acid-induced insulin resistance in adipocytes
Cell-specific expression of the rat secretogranin II promoter.
Cell-specific expression of the rat secretogranin II promoter
The peroxisome proliferator-activated receptor α is a phosphoprotein: Regulation by insulin
Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes
One of three CCArGG box/serum response elements of the β-actin gene is an insulin-responsive element
Regulation of glutamine:fructose-6-phosphate amidotransferase gene transcription by epidermal growth factor and glucose
Targeting of transforming growth factor-alpha expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas
Evidence for diverse roles of protein kinase-C in the inhibition of gene expression by insulin: the tyrosine aminotransferase, albumin, and phosphoenolpyruvate carboxykinase genes.
Adrenocorticotropic hormone stimulates a transient calcium uptake in rat lymphocytes.
Electron microscopic demonstration of insulin translocation to the cytoplasm and nuclei of intact H35 hepatoma cells using covalently linked Nanogold-insulin.
Synergistic induction of gene 33 expression by retinoic acid and insulin.
Adrenocorticotropic hormone stimulates a transient calcium uptake in rat lymphocytes
Binding of insulin-like growth factors (IGF-I and IGF-II) to the IGF-II/mannose 6-phosphate receptor in fetal rat myocardium
Calcitriol regulation of osteopontin expression in mouse epidermal cells
Insulin delivery in nosedrops: New formulations containing alkylglycosides
Insulin delivery in nosedrops: New formulations containing alkylglycosides
Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
Treatment of IM-9 cells with human growth hormone (GH) promotes rapid disulfide linkage of the GH receptor
Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes.
Identification of suppressin-producing cells in the rat pituitary.
Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: evidence of a cytosolic pathway.
Identification of suppressin-producing cells in the rat pituitary
Mitogen-stimulated lymphocytes release biologically active corticotropin
Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes
The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes
Glucose and insulin regulate insulin sensitivity in primary cultured adipocytes without affecting insulin receptor kinase activity
An antisense oligodeoxynucleotide to growth hormone messenger ribonucleic acid inhibits lymphocyte proliferation
Characterization of immunoreactive insulin-like growth factor-i from leukocytes and its regulation by growth hormone
Prostaglandins modulate hormonal effects on rabbit myometrial α1-adrenergic responses
Dexamethasone regulates the glucose transport system in primary cultured adipocytes: Different mechanisms of insulin resistance after acute and chronic exposure
Insulin and dexamethasone regulation of a rat hepatoma messenger ribonucleic acid: Insulin has a transcriptional and a posttranscriptional effect
Y-1 adrenocortical tumor cells contain atrial natriuretic peptide receptors which regulate cyclic nucleotide metabolism and steroidogenesis
Specific, high affinity receptors for insulin-like growth factor ii in the rat kidney glomerulus
Transcriptional regulation of a rat hepatoma gene by insulin and protein kinase-c
Age-related differences in the natriuretic and hypotensive properties of rat atrial extracts
Positive interaction between insulin and phorbol esters on the regulation of a specific messenger ribonucleic acid in rat hepatoma cells
Regression of renal hypertrophy and elevated renal na
-atpase activity after insulin treatment in streptozotocin-diabetic rats
Development of renal hypertrophy and increased renal Na,K-ATPase in streptozotocin-diabetic rats
Effect of tolazamide on basal ketogenesis, glycogenesis, and gluconeogenesis in liver obtained from normal and diabetic rats
Fetal rat hyperinsulinism and hyperglucagonism: Effects on hepatic ketogenesis, lipogenesis, and gluconeogenesis
Golden syrian hamsters: A new experimental model for adrenal compensatory hypertrophy
Identification and characterization of the insulin receptor of bovine retinal microvessels
A detailed analysis of the serum luteinizing hormone secretory profile in conscious, free-moving female rats during the time of puberty
A quantitative analysis of the maturation of steroid negative feedbacks controlling gonadotropin release in the female rat: The infantile-juvenile periods, transition from an androgenic to a predominantly estrogenic control
Development of estradiol-positive feedback on luteinizing hormone release in the female rat: A quantitative study
Changes in ovarian steroidal and prostaglandin e responsiveness to gonadotropins during the onset of puberty in the female rat
Acute stimulated hormone release from cultured GH
Organization of the medial hypothalamus for control of adrenocorticotropin in the cat
On the feedback actions of estrogen on gonadotropin and prolactin release in infantile female rats
Inhibitory and facilitatory areas of the rostral pons mediating acth release in the cat
Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat
Sex difference in fluid exchange during food deprivation in the rabbit.
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