Cancer Biology and Therapy

Ovarian cancer: new strategies and emerging targets for the treatment of patients with advanced disease.  22:89-105. 2021

The use of hedgehog antagonists in cancer therapy: a comparison of clinical outcomes and gene expression analyses.  21:873-883. 2020

Anti-cancer effects of the HuR inhibitor, MS-444, in malignant glioma cells.  20:979-988. 2019

Expression of steroid hormone receptors and its prognostic significance in urothelial carcinoma of the upper urinary tract.  17:1188-1196. 2016

Small molecule inhibitors of IRES-mediated translation.  16:1471-1485. 2015

KIFC1 is a novel potential therapeutic target for breast cancer.  16:1316-1322. 2015

Time-dependent pretreatment with bevacuzimab increases tumor specific uptake of cetuximab in preclinical oral cavity cancer studies.  16:790-798. 2015

Combination therapy with anti-DR5 antibody and tamoxifen for triple negative breast cancer.  15:1053-1060. 2014

Specific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growth.  15:510-515. 2014

Targeting the ERK pathway reduces liver metastasis of Smad4-inactivated colorectal cancer.  14:1059-1067. 2013

Identification of the optimal therapeutic antibody for fluorescent imaging of cutaneous squamous cell carcinoma.  14:271-277. 2013

Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes.  14:840-852. 2013

Combined modality therapy with TRAIL or agonistic death receptor antibodies.  11:431-449. 2011

TGFβ-dependent induction of interleukin-11 and interleukin-8 involves SMAD and p38 MAPK pathways in breast tumor models with varied bone metastases potential.  11:311-316. 2011

Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.  10:893-902. 2010

ErbB3 expression promotes tumorigenesis in pancreatic adenocarcinoma.  10:555-563. 2010

NADPH oxidase 4 is an oncoprotein localized to mitochondria.  10:223-231. 2010

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.  9:762-775. 2010

Exploiting cellular senescence to treat cancer and circumvent drug resistance.  9:166-175. 2010

Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS^Q61L.  9:122-133. 2010

Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling.  8:1840-1851. 2009

Cancer cell mitochondria confer apoptosis resistance and promote metastasis.  8:1378-1385. 2009

Cancer cell mitochondria confer apoptosis resistance and promote metastasis.  8:69-76. 2009

Death receptor 5 agonist TRA8 in combination with the bisphosphonate zoledronic acid attenuated the growth of breast cancer metastasis.  8:1109-1116. 2009

Cell adhesion molecules as targets for therapy of neuroblastoma.  8:306-311. 2009

Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.  8:285-294. 2009

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer.  8:94-100. 2009

Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.  8:289-298. 2009

New insights into the role of CXCR4 in prostate cancer metastasis.  7:1849-1851. 2008

New insights into the role of CXCR4 in prostate cancer metastasis.  7:1850-1852. 2008

Characterization of infectivity of knob-modified adenoviral vectors in glioma..  7:786-793. 2008

A novel role for mitochondria in regulating epigenetic modification in the nucleus.  7:1182-1190. 2008

Bad things happen in the basal layer KLF4 and squamous cell carcinoma.  7:783-785. 2008

Characterization of infectivity of knob-modified adenoviral vectors in glioma.  7:788-795. 2008

Tumorigenic transformation of human breast epithelial cells induced by mitochondrial DNA depletion.  7:1732-1743. 2008

ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis.  6:454-462. 2007

BRCA1 regulates γ-tubulin binding to centrosomes.  6:1853-1857. 2007

ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib.  6:548-554. 2007

PDGF BB induces VEGF secretion in ovarian cancer.  6:1951-1959. 2007

Single-photon emission computed tomography imaging with a humanized, apoptosis-inducing antibody targeting human death receptor 5 in pancreas and breast tumor xenografts.  6:1392-1398. 2007

Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.  5:674-683. 2006

Proteomic analysis of mitochondria-to-nucleus retrograde response in human cancer.  5:967-975. 2006

Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors.  4:1367-1373. 2005

Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer.  4:72-76. 2005

Effects of HIV-1 Nef, a cytotoxic viral protein, on the growth of primary colorectal cancer..  4:65-69. 2005

Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.  4:1203-1210. 2005

KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia.  4:1401-1408. 2005

Nuclear localization of RFC40 by RIα: A link between cellular signaling and proliferation.  4:444-445. 2005

Upping the bid on engineered inducible cell death.  4:537. 2005

Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons.  3:393-402. 2004

Rapamycins: Mechanism of action and cellular resistance.  2:222-232. 2003

Isolation and characterization of fourteen novel putative and nine known target genes of the p53 family.  2:56-63. 2003

Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis.  1:401-406. 2002