Immunity

A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans 2023

Fooling TLR4 to promote fungal virulence..  55:1591-1593. 2022

A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts.  55:494-511.e11. 2022

Analysis of SARS-CoV-2 variant mutations reveals neutralization escape mechanisms and the ability to use ACE2 receptors from additional species.  54:1611-1621.e5. 2021

Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development.  53:172-186.e6. 2020

Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development.  52:1105-1118.e9. 2020

Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.  52:650-667.e10. 2020

Erratum: The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids (Immunity (2017) 47(6) (1182–1196.e10), (S1074761317304892), (10.1016/j.immuni.2017.11.012)).  52:571. 2020

Erratum: Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus (Immunity (2018) 49(4) (725–739.e6), (S1074761318303789), (10.1016/j.immuni.2018.08.015)).  52:203. 2020

Erratum: The Immune Landscape of Cancer (Immunity (2018) 48(4) (812–830.e14), (S1074761318301213), (10.1016/j.immuni.2018.03.023)).  51:411-412. 2019

Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses.  51:155-168.e5. 2019

T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells.  50:1172-1187.e7. 2019

Defining Barriers that Impede Choices.  50:542-544. 2019

Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants.  50:225-240.e4. 2019

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.  49:725-739.e6. 2018

The Immune Landscape of Cancer.  48:812-830.e14. 2018

The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids.  47:1182-1196.e10. 2017

CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs.  47:251-267.e7. 2017

Fugue G Minor: Getting the Lymph Node Ensemble Together with Circadian Rhythm.  46:6-8. 2017

The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance.  45:831-846. 2016

Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis.  44:582-596. 2016

T Follicular Helper Cell Plasticity Shapes Pathogenic T Helper 2 Cell-Mediated Immunity to Inhaled House Dust Mite.  44:259-273. 2016

IgM Memory Cells: First Responders in Malaria.  45:235-237. 2016

Long-Lived Plasma Cells Are Contained within the CD19^-CD38^hiCD138⁺ Subset in Human Bone Marrow.  43:132-145. 2015

Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8⁺ T Cells.  41:127-140. 2014

A stay of execution: Type I Interferons Pardon T cells from death by natural killers.  40:861-862. 2014

The transcription factors T-bet and runx are required for the ontogeny of pathogenic interferon-γ-producing T helper 17 cells.  40:355-366. 2014

Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals.  39:148-159. 2013

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling.  38:461-474. 2013

Interferon-Inducible Cholesterol-25-Hydroxylase Broadly Inhibits Viral Entry by Production of 25-Hydroxycholesterol.  38:92-105. 2013

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria.  37:1061-1075. 2012

γδ T Cells Recognize a Microbial Encoded B Cell Antigen to Initiate a Rapid Antigen-Specific Interleukin-17 Response.  37:524-534. 2012

Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation.  36:847-856. 2012

Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2.  36:23-31. 2012

Th17 Cells Mediate Clade-Specific, Serotype-Independent Mucosal Immunity.  35:997-1009. 2011

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation.  35:871-882. 2011

Memory: The Incomplete Unhappening of Differentiation.  35:496-498. 2011

Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates.  35:45-58. 2011

Experimental inflammatory bowel disease: Insights into the host-microbiota dialog.  34:293-302. 2011

TGF-β in Th17 cell development: The truth is out there.  34:288-290. 2011

Follicular dendritic cell makes environmental sense.  33:2-4. 2010

Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli.  33:35-47. 2010

Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage.  32:616-627. 2010

Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis.  32:414-425. 2010

Interleukin-17 Is Required for T Helper 1 Cell Immunity and Host Resistance to the Intracellular Pathogen Francisella tularensis.  31:799-810. 2009

CCCTC-Binding Factor and the Transcription Factor T-bet Orchestrate T Helper 1 Cell-Specific Structure and Function at the Interferon-γ Locus.  31:551-564. 2009

Intestinal Effector T Cells in Health and Disease.  31:389-400. 2009

Omental Milky Spots Develop in the Absence of Lymphoid Tissue-Inducer Cells and Support B and T Cell Responses to Peritoneal Antigens.  30:731-743. 2009

Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling.  30:576-587. 2009

Cytokine-Producing Effector B Cells Regulate Type 2 Immunity to H. polygyrus.  30:421-433. 2009

The Lymphotoxin LTα1β2 Controls Postnatal and Adult Spleen Marginal Sinus Vascular Structure and Function.  30:408-420. 2009

Late Developmental Plasticity in the T Helper 17 Lineage.  30:92-107. 2009

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages (DOI:10.1016/j.immuni.2008.05.009).  29:318. 2008

Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages.  29:138-149. 2008

Molecular Antagonism and Plasticity of Regulatory and Inflammatory T Cell Programs.  29:44-56. 2008

T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ.  28:29-39. 2008

Tumor Suppressor CYLD Regulates Acute Lung Injury in Lethal Streptococcus pneumoniae Infections.  27:349-360. 2007

Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania..  26:519-531. 2007

A Distal Conserved Sequence Element Controls Ifng Gene Expression by T Cells and NK Cells.  25:717-729. 2006

Persistence and Responsiveness of Immunologic Memory in the Absence of Secondary Lymphoid Organs.  25:643-654. 2006

Toll-like Receptor 7-Dependent Loss of B Cell Tolerance in Pathogenic Autoantibody Knockin Mice.  25:429-440. 2006

Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties.  24:677-688. 2006

Taking control of follicular dendritic cells.  24:13-15. 2006

T-bet regulates the terminal maturation and homeostasis of NK and Vα14i NKT cells.  20:477-494. 2004

Regulation of dendritic cell trafficking by the ADP-ribosyl cyclase CD38: Impact on the development of humoral immunity.  20:279-291. 2004

Contribution of VH gene replacement to the primary B cell repertoire.  19:21-31. 2003

Complement receptors CD21/35 link innate and protective immunity during Streptococcus pneumoniae infection by regulating IgG3 antibody responses.  17:713-723. 2002

Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.  17:341-352. 2002

Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.  15:35-46. 2001

Lymphotoxins and cytomegalovirus cooperatively induce interferon-β, establishing host-virus Détente.  15:617-626. 2001

Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens.  14:617-629. 2001

Superantigen recognition by γδ T cells: SEA recognition site for human Vγ2 T cell receptors.  14:331-344. 2001

Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk.  12:39-49. 2000

A developmental switch from TCRδ enhancer to TCRα enhancer function during thymocyte maturation.  10:723-733. 1999

Developmental regulation of TCRδ locus accessibility and expression by the TCRδ enhancer.  10:503-513. 1999

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion.  10:537-546. 1999

Increased junctional diversity in fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice.  10:607-617. 1999

Interleukin-2 expression by a subpopulation of primary T cells is linked to enhanced memory/effector function.  11:271-280. 1999

Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription.  11:665-675. 1999

Arrest of B lymphocyte terminal differentiation by CD40 signaling: Mechanism for lack of antibody-secreting cells in germinal centers.  8:733-742. 1998

Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection.  8:177-187. 1998

Function of the TCRα enhancer in αβ and γδ T cells.  7:505-515. 1997

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6..  6:47-56. 1997

Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis.  2:353-362. 1995