Endocrinology

Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes.  163. 2022

Retraction: Mechanisms of hemorrhage-induced hepatic insulin resistance: Role of tumor necrosis factor-α (Endocrinology (2004) 145:11 (5168-5176) DOI: 10.1210/en.2004-0524).  162. 2021

Human Glucagon Expression Is under the Control of miR-320a.  162. 2021

Human Glucagon Expression Is under the Control of miR-320a..  162. 2021

Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ.  162. 2021

Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ..  162. 2021

Antifibrogenic Activities of CYP11A1-derived Vitamin D3-hydroxyderivatives Are Dependent on RORγ..  162. 2021

Glucagon-receptor signaling reverses hepatic steatosis independent of leptin receptor expression.  161. 2020

Prolactin receptor signaling regulates a pregnancy-specific transcriptional program in mouse islets.  160:1150-1163. 2019

G Protein-Coupled Estrogen Receptor Is Not Required for Sex Determination or Ovary Function in Zebrafish.  159:3515-3523. 2018

How UV Light Touches the Brain and Endocrine System Through Skin, and Why.  159:1992-2007. 2018

Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish.  159:980-993. 2018

Dietary manipulations that induce ketosis activate the HPA axis in male rats and mice: A potential role for fibroblast growth factor-21.  159:400-413. 2018

Subdomain 2, not the transmembrane domain, determines the dimerization partner of growth hormone receptor and prolactin receptor.  158:3235-3248. 2017

Insulin, IGF-1, and GH receptors are altered in an adipose tissue depot-specific manner in male mice with modified GH action.  158:1406-1418. 2017

LDB1 regulates energy homeostasis during diet-induced obesity.  158:1289-1297. 2017

Brown adipose tissue function is enhanced in long-lived, male ames dwarf mice.  157:4744-4753. 2016

Effect of n-3 and n-6 polyunsaturated fatty acids on microsomal P450 steroidogenic enzyme activities and in vitro cortisol production in adrenal tissue from yorkshire boars.  157:1512-1521. 2016

N¹-acetyl-5-methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.  156:1630-1636. 2015

Skin under the sun: When melanin pigment meets vitamin D.  156:1-4. 2015

Evidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.  155:3352-3364. 2014

Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells.  155:1000-1009. 2014

High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit.  155:380-391. 2014

Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: Involvement of cAMP/PKA signaling.  155:576-591. 2014

Liver-Specific gh receptor gene-Disrupted (lighrko) mice have decreased endocrine igf-I, increased local igf-I, and altered body size, body composition, and adipokine profiles.  155:1793-1805. 2014

Glucocorticoid-dependent hippocampal transcriptome in male rats: Pathway-specific alterations with aging.  154:2807-2820. 2013

Hepatic growth hormone resistance after acute injury.  154:1577-1588. 2013

Hormonal contraception and hiv-1 infection: Medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms.  154:1282-1295. 2013

Central depletion of brain-derived neurotrophic,factorin mice results in high bone mass and metabolic phenotype.  153:5394-5405. 2012

Acylation type determines Ghrelin's effects on energy homeostasis in rodents.  153:4687-4695. 2012

AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol.  153:2130-2141. 2012

Growth hormone-induced JAK2 signaling and GH receptor down-regulation: Role of GH receptor intracellular domain tyrosine residues.  153:2311-2322. 2012

Antiapoptotic actions of exendin-4 against hypoxia and cytokines are augmented by CREB.  153:1116-1128. 2012

Inhibitory GH receptor extracellular domain monoclonal antibodies: Three-dimensional epitope mapping.  152:4777-4788. 2011

Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance.  152:3373-3384. 2011

Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice.  151:3536-3542. 2010

Erratum: Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin (Endocrinology (2009) 150, (1636-1645) DOI: 10.1210/en.2008-1102).  151:2967. 2010

Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: Roles for AMP-activated protein kinase, Akt, and FOXO1.  151:103-114. 2010

Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.  150:1636-1645. 2009

Increased energy expenditure and insulin sensitivity in the high bone mass DeltaFosB transgenic mice..  150:135-143. 2009

Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury.  150:24-32. 2009

Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k.  149:3196-3205. 2008

Protein kinase C-ζ phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: Isoform specific determinants of specificity in insulin signaling.  149:2451-2458. 2008

Trauma and hemorrhage-induced acute hepatic insulin resistance: Dominant role of tumor necrosis factor-α.  149:2369-2382. 2008

Cardiac hypertrophy caused by peroxisome proliferator-activated receptor-γ agonist treatment occurs independently of changes in myocardial insulin signaling.  148:6047-6053. 2007

Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells.  148:5955-5965. 2007

Genistein attenuates the hypertensive effects of dietary NaCl in hypertensive male rats.  148:5396-5402. 2007

Enhanced voluntary alcohol consumption after estrogen supplementation negates estrogen-mediated vascular repair in ovariectomized mice.  148:3618-3624. 2007

Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoter.  148:3307-3315. 2007

Identification of the glomerular podocyte as a target for growth hormone action.  148:2045-2055. 2007

Role of microsomal retinol/sterol dehydrogenase-like short-chain dehydrogenases/reductases in the oxidation and epimerization of 3α-hydroxysteroids in human tissues.  148:2148-2156. 2007

Growth hormone, insulin-like growth factor I, and growth: Local knowledge.  148:1486-1488. 2007

Insulin-like growth factor-I stimulates histone H3 and H4 acetylation in the brain in vivo.  147:5480-5490. 2006

Janus kinase 2 influences growth hormone receptor metalloproteolysis.  147:2839-2849. 2006

Reduced Cardiac Efficiency and Altered Substrate Metabolism Precedes the Onset of Hyperglycemia and Contractile Dysfunction in Two Mouse Models of Insulin Resistance and Obesity.  146:5341-5349. 2005

Janus kinase 2 enhances the stability of the mature growth hormone receptor.  146:4755-4765. 2005

Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span.  146:2920-2932. 2005

Blockade of rapid versus prolonged extracellularly regulated kinase 1/2 activation has differential effects on insulin-induced gene expression.  146:2716-2725. 2005

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces β-cell apoptosis.  146:2397-2405. 2005

Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice.  146:1138-1144. 2005

Preservation of eumelanin hair pigmentation in proopiomelanocortin- deficient mice on a nonagouti (a/a) genetic background.  146:1245-1253. 2005

Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor I/insulin signaling and caloric restriction.  146:851-860. 2005

Growth hormone alters epidermal growth factor receptor binding affinity via activation of extracellular signal-regulated kinases in 3T3-F442A cells.  145:3297-3306. 2004

Modeled microgravity inhibits osteogenic differentiation of human mesenchymal stem cells and increases adipogenesis.  145:2421-2432. 2004

Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: Microarray deoxyribonucleic acid-chip analysis of gene expression.  145:2035-2045. 2004

Activation of the Retinoid X Receptor Suppresses Appetite in the Rat.  145:565-573. 2004

Differential Expression of a Cutaneous Corticotropin-Releasing Hormone System.  145:941-950. 2004

Mechanisms of hemorrhage-induced hepatic insulin resistance: Role of tumor necrosis factor-α.  145:5168-5176. 2004

Insulin-Regulated Expression of Egr-1 and Krox20: Dependence on ERK1/2 and Interaction with p38 and PI3-Kinase Pathways.  144:5402-5410. 2003

Osteoclast Apoptosis: The Role of Fas in Vivo and in Vitro.  144:5545-5555. 2003

The role of calmodulin in the regulation of osteoclastogenesis.  144:4536-4543. 2003

Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1,25 dihydroxyvitamin D3 in the intestine and kidney of mice.  144:3885-3894. 2003

Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: Interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway.  144:3969-3976. 2003

Ovine placental lactogen-induced heterodimerization of ovine growth hormone and prolactin receptors in living cells is demonstrated by fluorescence resonance energy transfer microscopy and leads to prolonged phosphorylation of signal transducer and activator of transcription (STAT)1 and STAT3.  144:3532-3540. 2003

Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold.  144:2580-2587. 2003

A role for Grb2-associated binder-1 in growth hormone signaling.  143:4856-4867. 2002

Tyrosines 559 and 807 in the cytoplasmic tail of the macrophage colony-stimulating factor receptor play distinct roles in osteoclast differentiation and function.  143:4868-4874. 2002

Oligonucleotide microarray analysis of intact human pancreatic islets: Identification of glucose-responsive genes and a highly regulated TGFβ signaling pathway.  143:3695-3698. 2002

Impairment of Liver GH Receptor Signaling by Fasting..  143:792-800. 2002

A proinsulin gene splice variant with increased translation efficiency is expressed in human pancreatic islets.  143:2541-2547. 2002

Impairment of liver GH receptor signaling by fasting.  143:792-800. 2002

Minireview: Receptor Dimerization in GH and Erythropoietin Action-It Takes Two to Tango, But How?.  143:2-10. 2002

Minireview: Receptor dimerization in GH and erythropoietin action - It takes two to Tango, but how?.  143:2-10. 2002

White adipocyte vascular endothelial growth factor: Regulation by insulin.  143:948-953. 2002

Inhibition of central amylin signaling increases food intake and body adiposity in rats.  142:5035-5038. 2001

Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype.  142:4026-4039. 2001

Divergent Immune Responses in Male and Female Mice after Trauma-Hemorrhage: Dimorphic Alterations in T Lymphocyte Steroidogenic Enzyme Activities..  142:3519-3529. 2001

Immediate and prolonged patterns of Agouti-related peptide-(83--132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites..  142:1050-1056. 2001

Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid- treated rabbits..  142:1333-1340. 2001

Differential regulation of the two principal Runx2/Cbfa1 N-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.  142:4026-4039. 2001

Divergent immune responses in male and female mice after trauma-hemorrhage: Dimorphic alterations in T lymphocyte steroidogenic enzyme activities.  142:3519-3529. 2001

Immediate and prolonged patterns of Agouti-related peptide-(83-132)-induced c-Fos activation in hypothalamic and extrahypothalamic sites.  142:1050-1056. 2001

Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: Relationship to GH receptor down-regulation.  142:1137-1147. 2001

Receptor activator of nuclear factor-κB ligand activates nuclear factor-κB in osteoclast precursors.  142:1290-1295. 2001

Regional trabecular bone matrix degeneration and osteocyte death in femora of glucocorticoid-treated rabbits.  142:1333-1340. 2001

Amylin: A novel action in the brain to reduce body weight.  141:850-853. 2000

Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation..  141:4342-4348. 2000

A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse..  141:3518-3521. 2000

Amylin: a novel action in the brain to reduce body weight..  141:850-853. 2000

A unique metabolic syndrome causes obesity in the melanocortin-3 receptor-deficient mouse.  141:3518-3521. 2000

Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation.  141:3328-3336. 2000

Tumor necrosis factor α regulates αvβ5 integrin expression by osteoclast precursors in vitro and in vivo.  141:284-290. 2000

Tumor necrosis factor-α converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: The metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation.  141:4342-4348. 2000

Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione..  140:1151-1157. 1999

Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells.  140:3073-3081. 1999

Insulin receptor substrate-1 enhances growth hormone-induced proliferation.  140:1972-1983. 1999

Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: Decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione.  140:1151-1157. 1999

Mass Spectrometric Evidence That Agents That Cause Loss of Ca2+ from Intracellular Compartments Induce Hydrolysis of Arachidonic Acid from Pancreatic Islet Membrane Phospholipids by a Mechanism That Does Not Require a Rise in Cytosolic Ca2+ Concentration* * This work was supported by U.S. Public Health Service grants PO1-HL57278, P41-RR-00954, and S10-RR-11260 and by an American Diabetes Association Career Development Award (S.R.)..  139:4073-4085. 1998

Blockade of growth hormone receptor shedding by a metalloprotease inhibitor.  139:1927-1935. 1998

Mass spectrometric evidence that agents that cause loss of Ca²⁺ from intracellular compartments induce hydrolysis of arachidonic acid from pancreatic islet membrane phospholipids by a mechanism that does not require a rise in cytosolic Ca²⁺ concentration.  139:4073-4085. 1998

Expression and Subcellular Distribution of the β-Isoform of the Human Glucocorticoid Receptor..  138:5028-5038. 1997

A role for phospholipase C activity in GLUT4-mediated glucose transport.  138:5170-5175. 1997

Fatty acid-induced insulin resistance in adipocytes.  138:4338-4345. 1997

Cell-specific expression of the rat secretogranin II promoter..  137:3815-3822. 1996

Cell-specific expression of the rat secretogranin II promoter.  137:3815-3822. 1996

The peroxisome proliferator-activated receptor α is a phosphoprotein: Regulation by insulin.  137:4499-4502. 1996

Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes.  136:431-439. 1995

One of three CCArGG box/serum response elements of the β-actin gene is an insulin-responsive element.  136:306-315. 1995

Regulation of glutamine:fructose-6-phosphate amidotransferase gene transcription by epidermal growth factor and glucose.  136:2809-2816. 1995

Targeting of transforming growth factor-alpha expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas.  136:4479-4488. 1995

Evidence for diverse roles of protein kinase-C in the inhibition of gene expression by insulin: the tyrosine aminotransferase, albumin, and phosphoenolpyruvate carboxykinase genes..  135:2327-2334. 1994

Adrenocorticotropic hormone stimulates a transient calcium uptake in rat lymphocytes..  135:1780-1786. 1994

Electron microscopic demonstration of insulin translocation to the cytoplasm and nuclei of intact H35 hepatoma cells using covalently linked Nanogold-insulin. 1994

Synergistic induction of gene 33 expression by retinoic acid and insulin..  134:2237-2244. 1994

Adrenocorticotropic hormone stimulates a transient calcium uptake in rat lymphocytes.  135:1780-1786. 1994

Binding of insulin-like growth factors (IGF-I and IGF-II) to the IGF-II/mannose 6-phosphate receptor in fetal rat myocardium.  135:231-239. 1994

Calcitriol regulation of osteopontin expression in mouse epidermal cells.  135:863-869. 1994

Insulin delivery in nosedrops: New formulations containing alkylglycosides.  135:2386-2391. 1994

Insulin delivery in nosedrops: New formulations containing alkylglycosides.  135:2386-2391. 1994

Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.  135:2228-2239. 1994

Treatment of IM-9 cells with human growth hormone (GH) promotes rapid disulfide linkage of the GH receptor.  135:148-156. 1994

Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes..  133:2943-2950. 1993

Identification of suppressin-producing cells in the rat pituitary..  133:241-247. 1993

Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: evidence of a cytosolic pathway..  132:2293-2298. 1993

Identification of suppressin-producing cells in the rat pituitary.  133:241-247. 1993

Mitogen-stimulated lymphocytes release biologically active corticotropin.  132:983-988. 1993

Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes.  133:2943-2950. 1993

The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes.  130:3694-3702. 1992

Glucose and insulin regulate insulin sensitivity in primary cultured adipocytes without affecting insulin receptor kinase activity.  128:2415-2426. 1991

An antisense oligodeoxynucleotide to growth hormone messenger ribonucleic acid inhibits lymphocyte proliferation.  128:2053-2057. 1991

Characterization of immunoreactive insulin-like growth factor-i from leukocytes and its regulation by growth hormone.  129:1727-1734. 1991

Prostaglandins modulate hormonal effects on rabbit myometrial α1-adrenergic responses.  129:1436-1442. 1991

Dexamethasone regulates the glucose transport system in primary cultured adipocytes: Different mechanisms of insulin resistance after acute and chronic exposure.  124:2063-2073. 1989

Insulin and dexamethasone regulation of a rat hepatoma messenger ribonucleic acid: Insulin has a transcriptional and a posttranscriptional effect.  124:754-761. 1989

Y-1 adrenocortical tumor cells contain atrial natriuretic peptide receptors which regulate cyclic nucleotide metabolism and steroidogenesis.  125:2341-2349. 1989

Specific, high affinity receptors for insulin-like growth factor ii in the rat kidney glomerulus.  123:774-780. 1988

Transcriptional regulation of a rat hepatoma gene by insulin and protein kinase-c.  123:366-372. 1988

Age-related differences in the natriuretic and hypotensive properties of rat atrial extracts.  121:1662-1670. 1987

Positive interaction between insulin and phorbol esters on the regulation of a specific messenger ribonucleic acid in rat hepatoma cells.  121:1227-1232. 1987

Regression of renal hypertrophy and elevated renal na⁺, k⁺-atpase activity after insulin treatment in streptozotocin-diabetic rats.  120:2166-2173. 1987

Development of renal hypertrophy and increased renal Na,K-ATPase in streptozotocin-diabetic rats.  119:672-679. 1986

Golden syrian hamsters: A new experimental model for adrenal compensatory hypertrophy.  114:1490-1495. 1984

Identification and characterization of the insulin receptor of bovine retinal microvessels.  115:698-704. 1984

A detailed analysis of the serum luteinizing hormone secretory profile in conscious, free-moving female rats during the time of puberty.  109:2032-2039. 1981

A quantitative analysis of the maturation of steroid negative feedbacks controlling gonadotropin release in the female rat: The infantile-juvenile periods, transition from an androgenic to a predominantly estrogenic control.  108:1313-1320. 1981

Development of estradiol-positive feedback on luteinizing hormone release in the female rat: A quantitative study.  109:1404-1413. 1981

Changes in ovarian steroidal and prostaglandin e responsiveness to gonadotropins during the onset of puberty in the female rat.  104:653-658. 1979

Acute stimulated hormone release from cultured GH3 pituitary cells.  103:1245-1252. 1978

Organization of the medial hypothalamus for control of adrenocorticotropin in the cat.  103:957-970. 1978

On the feedback actions of estrogen on gonadotropin and prolactin release in infantile female rats.  101:1517-1523. 1977

Inhibitory and facilitatory areas of the rostral pons mediating acth release in the cat.  99:1220-1228. 1976

Inhibitory and facilitatory hypothalamic areas mediating ACTH release in the cat.  95:1450-1461. 1974

Sex difference in fluid exchange during food deprivation in the rabbit..  78:291-296. 1966