Cardiovascular Research

FAK in the nucleus prevents VSMC proliferation by promoting p27 and p21 expression via Skp2 degradation.  118:1150-1163. 2022

Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart.  118:212-225. 2022

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.  117:2767-2780. 2021

Cardiac natriuretic peptide deficiency sensitizes the heart to stress induced ventricular arrhythmias via impaired CREB signaling. 2021

HDAC1: an environmental sensor regulating endothelial function. 2021

Angiopoietin-1 enhanced myocyte mitosis, engraftment, and the reparability of hiPSC-CMs for treatment of myocardial infarction.  117:1578-1591. 2021

mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification. 2021

Classical monocyte transcriptomes reveal significant anti-inflammatory statin effect in women with chronic HIV.  117:1166-1177. 2021

N-cadherin overexpression enhances the reparative potency of human-induced pluripotent stem cell-derived cardiac myocytes in infarcted mouse hearts.  116:671-685. 2020

Loss of CXCR4 on non-classical monocytes in participants of the Women's Interagency HIV Study (WIHS) with subclinical atherosclerosis.  115:1029-1040. 2019

Ponatinib-induced cardiotoxicity: Delineating the signalling mechanisms and potential rescue strategies.  115:966-977. 2019

Acute, local infusion of angiotensin II impairs microvascular and metabolic insulin sensitivity in skeletal muscle.  115:590-601. 2019

Y-27632 preconditioning enhances transplantation of human-induced pluripotent stem cell-derived cardiomyocytes in myocardial infarction mice.  115:343-356. 2019

Associations between cardiovascular disease, cancer, and very low high-density lipoprotein cholesterol in the REasons for Geographical and Racial Differences in Stroke (REGARDS) study.  115:204-212. 2019

Inhibition of GSK-3 to induce cardiomyocyte proliferation: a recipe for in situ cardiac regeneration.  115:20-30. 2019

Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration.  114:188-199. 2018

Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis.  113:938-949. 2017

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice.  112:532-542. 2016

Sema6D acts downstream of bone morphogenetic protein signalling to promote atrioventricular cushion development in mice..  112:532-542. 2016

Normalization of cardiac substrate utilization and left ventricular hypertrophy precede functional recovery in heart failure regression.  110:249-257. 2016

Impaired mitochondrial network excitability in failing Guinea-pig cardiomyocytes.  109:79-89. 2016

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.  107:235-245. 2015

Non-voltage-gated Ca²⁺ entry pathways in the heart: The untold STOrai?.  105:233-234. 2015

Renalase is a novel target gene of hypoxia-inducible factor-1 in protection against cardiac ischaemia-reperfusion injury.  105:182-191. 2015

Hunt for the culprit of cardiovascular injury in kidney disease.  108:209-211. 2015

E2F1 suppresses cardiac neovascularization by down-regulating VEGF and PlGF expression.  104:412-422. 2014

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation.  99:442-451. 2013

Prolongation of minimal action potential duration in sustained fibrillation decreases complexity by transient destabilization.  98:155-156. 2013

C-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmias.  97:589-597. 2013

Panoramic optical mapping shows wavebreak at a consistent anatomical site at the onset of ventricular fibrillation.  93:272-279. 2012

Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43.  92:106-114. 2011

Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation.  91:27-36. 2011

Cardiac anaplerosis in health and disease: Food for thought.  90:210-219. 2011

Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.  90:353-363. 2011

Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblasts.  90:88-96. 2011

The detection of the nitrite reductase and NO-generating properties of haemoglobin by mitochondrial inhibition.  89:566-573. 2011

The paradoxical world of protein O-GlcNAcylation: A novel effector of cardiovascular (dys)function.  89:487-488. 2011

The potential role of the red blood cell in nitrite-dependent regulation of blood flow.  89:507-515. 2011

Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure.  89:129-138. 2011

Erythropoietin and ventricular remodelling: A VEGF-dependent neovascularity.  87:6-7. 2010

Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytes.  85:751-762. 2010

Dipyridamole enhances ischaemia-induced arteriogenesis through an endocrine nitrite/nitric oxide-dependent pathway.  85:661-670. 2010

Glucocorticoid response elements and 11β-hydroxysteroid dehydrogenases in the regulation of endothelial nitric oxide synthase expression.  81:140-147. 2009

Diurnal variations in myocardial metabolism.  79:228-237. 2008

Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure.  79:331-340. 2008

Downregulation of CuZn-superoxide dismutase contributes to β-adrenergic receptor-mediated oxidative stress in the heart.  74:445-455. 2007

Role of protein O-linked N-acetyl-glucosamine in mediating cell function and survival in the cardiovascular system.  73:288-297. 2007

Shock-induced changes of Cai²⁺ and Vm in myocyte cultures and computer model: Dependence on the timing of shock application.  73:101-110. 2007

Activation of gadolinium-sensitive ion channels in cardiomyocytes in early adaptive stages of volume overload-induced heart failure.  72:262-270. 2006

Reactive oxygen species in vascular endothelial cell motility. Roles of NAD(P)H oxidase and Rac1.  71:236-246. 2006

Reduced endothelial secretion and plasma levels of transforming growth factor-β1 in patients with hereditary hemorrhagic telangiectasia type 1.  68:155-164. 2005

Carnitine palmitoyl transferase-I inhibition prevents ventricular remodeling and delays decompensation in pacing-induced heart failure.  66:454-461. 2005

Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1.  65:719-727. 2005

High-resolution optical mapping of intramural virtual electrodes in porcine left ventricular wall.  64:448-456. 2004

Volume overload results in exaggerated cardiac hypertrophy in the atrial natriuretic peptide knockout mouse.  61:771-779. 2004

Spontaneous activity induced in rabbit Purkinje myocytes during coupling to a depolarized model cell.  59:620-627. 2003

Intracellular Na in animal models of hypertrophy and heart failure: Contractile function and arrhythmogenesis.  57:887-896. 2003

Modulation of triggered activity by uncoupling in the ischemic border: A model study with phase 1b-like conditions.  56:381-392. 2002

Cardiac carbohydrate metabolism in Zucker diabetic fatty rats.  55:104-112. 2002

Pyruvate dehydrogenase and the regulation of glucose oxidation in hypertrophied rat hearts.  53:841-851. 2002

Sex hormones and hypertension.  53:688-708. 2002

Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury.  52:387-396. 2001

Transient outward current modulates discontinuous conduction in rabbit ventricular cell pairs.  49:779-789. 2001

Mechanisms of the pro- and anti-oxidant actions of nitric oxide in atherosclerosis.  47:465-474. 2000

Estrogen attenuates the adventitial contribution to neointima formation in injured rat carotid arteries.  44:608-614. 1999

Hemodynamic effects of nitric oxide synthase inhibition at steady state and following tumor necrosis factor-α-induced myodepression.  44:527-535. 1999

Load sensitivity of left ventricular relaxation in normal and failing hearts: Evidence of a nonlinear biphasic response.  43:354-363. 1999

Preferential inhibition of lactate oxidation relative to glucose oxidation in the rat heart following diabetes.  43:96-106. 1999

Myocardial oxygenation at high workstates in hearts with left ventricular hypertrophy.  42:616-626. 1999

Ryanodine and the left ventricular force-interval and relaxation- interval relations in closed-chest dogs: Insights on calcium handling.  40:483-491. 1998

Nitric oxide-dependent and independent effects on human platelets treated with peroxynitrite.  40:380-388. 1998

MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKC(ε) proteolysis in reperfused ferret hearts.  35:60-67. 1997

Role of wavefront curvature in propagation of cardiac impulse.  33:258-271. 1997

Acute L-triiodothyronine administration potentiates inotropic responses to β-adrenergic stimulation in the isolated perfused rat heart.  32:306-310. 1996

Right and left ventricular geometry and myocyte contractile processes with dilated cardiomyopathy: Myocyte growth and β-adrenergic responsiveness.  31:314-323. 1996

Block of impulse propagation at an abrupt tissue expansion: evaluation of the critical strand diameter in 2- and 3-dimensional computer models.  30:449-459. 1995

Block of impulse propagation at an abrupt tissue expansion: Evaluation of the critical strand diameter in 2- and 3-dimensional computer models.  30:449-459. 1995

Cardiac tissue geometry as a determinant of unidirectional conduction block: Assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model.  29:697-707. 1995

Hypoxia activates nitric oxide synthase and stimulates nitric oxide production in porcine coronary resistance arteriolar endothelial cells.  30:841-847. 1995

Quantification and localisation of angiotensin II receptors and angiotensin converting enzyme in the developing rat heart.  29:834-840. 1995

Estimates of beat to beat handling of activator calcium using measurements of [Ca²⁺]i in aequorin loaded ferret cardiac muscle.  28:40-46. 1994

Cardiac tissue geometry as a determinant of unidirectional conduction block: Assessment of microscopic excitation spread by optical mapping in patterned cell cultures and in a computer model.  28:697-707. 1994

Quantification and localisation of angiotensin ii receptors and angiotensin converting enzyme in the developing rat heart.  28:834-840. 1994

Estimates of beat to beat handling of activator calcium using measurements of [Ca²⁺]i in aequorin loaded ferret cardiac muscle.  28:40-46. 1994

A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imaging.  27:974-979. 1993

A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imaging.  27:974-979. 1993

Effect of adenosine on coronary blood flow and its use as a diagnostic test for coronary artery disease.  27:48-53. 1993

Effect of adenosine on coronary blood flow and its use as a diagnostic test for coronary artery disease.  27:48-53. 1993

Ventricular coupling via the pericardium: Normal versus tamponade.  27:1470-1476. 1993

Effect of ventilatory strategy on cardiac output during high frequency jet ventilation.  25:309-313. 1991

Effect of ventilatory strategy on cardiac output during high frequency jet ventilation.  25:309-313. 1991

Application of a time varying elastance model to right ventricular performance in man.  22:864-874. 1988

Depletion of myocardial glutathione: Its effects on heart function and metabolism during ischaemia and reperfusion.  22:833-839. 1988

Parasympathetic and sympathetic efferent traffic during a cardiogenic hypertensive chemoreflex.  18:583-590. 1984

Influences of labetalol a combined α- and β-adrenergic blocking agent on the dysrhythmias induced by coronary occlusion and reperfusion.  16:398-407. 1982

Regional flow patterns during the serotonin-induced cardiogenic hypertensive chemoreflex.  14:169-176. 1980

Electrophysiological and mathematical characteristics of the escape rhythm during complete AV block.  8:173-186. 1974

Selective effects of pentobarbital on automaticity and conduction in the intact canine heart.  8:46-57. 1974