Journal of Biological Chemistry

Journal

Publication Venue For

  • Nuclear focal adhesion kinase induces APC/C activator protein CDH1-mediated cyclin-dependent kinase 4/6 degradation and inhibits melanoma proliferation..  298:102013. 2022
  • ST6Gal-I-mediated sialylation of the epidermal growth factor receptor modulates cell mechanics and enhances invasion.  298. 2022
  • Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer.  298. 2022
  • Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathy.  298. 2022
  • Dehydrogenase reductase 9 (SDR9C4) and related homologs recognize a broad spectrum of lipid mediator oxylipins as substrates.  298. 2022
  • The small molecule BMH-21 directly inhibits transcription elongation and DNA occupancy of RNA polymerase I in vivo and in vitro.  298. 2022
  • The macromolecular complexes of histones affect protein arginine methyltransferase activities.  279. 2021
  • Delivering progranulin to neuronal lysosomes protects against excitotoxicity.  297. 2021
  • Intrinsically disordered electronegative clusters improve stability and binding specificity of RNA-binding proteins.  297. 2021
  • Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury.  297. 2021
  • NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.  297. 2021
  • Erratum: Definingα-synuclein species responsible for Parkinson's disease phenotypes in mice (J Biol Chem (2019) 294:27 (10392-10406) DOI: 10.1074/jbc.RA119.007743).  295:1142. 2021
  • A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.  296. 2021
  • Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes.  296. 2021
  • Defining the divergent enzymatic properties of RNA polymerases I and II.  296. 2021
  • Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.  296. 2021
  • Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation.  296. 2021
  • Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology.  295:17935-17949. 2020
  • A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins.  295:16949-16959. 2020
  • A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism..  296:100125. 2020
  • Defining the divergent enzymatic properties of RNA polymerases I and II..  296:100051. 2020
  • Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells..  296:100034. 2020
  • Cadmium-mediated lung injury is exacerbated by the persistence of classically activated macrophages.  295:15754-15766. 2020
  • Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover.  295:14153-14163. 2020
  • Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.  295:8413-8424. 2020
  • The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein.  295:8005-8016. 2020
  • The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I.  295:1153-1164. 2020
  • 14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation.  295:1754-1766. 2020
  • Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I.  295:1288-1299. 2020
  • Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I.  295:1288-1299. 2020
  • Erratum: Definingα-synuclein species responsible for Parkinson's disease phenotypes in mice (Journal of Biological Chemistry (2019) 294 (10392–10406) DOI: 10.1074/jbc.RA119.007743).  295:1142. 2020
  • First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart.  295:2018-2033. 2020
  • Pulmonary surfactant lipids inhibit infections with the pandemic H1N1 influenza virus in several animal models.  295:1704-1715. 2020
  • Structural and biophysical characterizations of HIV-1 matrix trimer binding to lipid nanodiscs shed light on virus assembly.  294:18600-18612. 2019
  • Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3-mediated gene silencing.  294:16930-16941. 2019
  • Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands.  294:17060-17074. 2019
  • Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease.  294:15604-15612. 2019
  • Distinct Fcα receptor N-glycans modulate the binding affinity to immunoglobulin A (IgA) antibodies.  294:13995-14008. 2019
  • LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet-cell function.  294:11728-11740. 2019
  • Hypoxia induces cancer cell-specific chromatin interactions and increases MALAT1 expression in breast cancer cells.  294:11213-11224. 2019
  • Correction: Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1 (Journal of Biological Chemistry (2013) 288 (33927-33938) DOI: 10.1074/jbc.M113.500983).  294:10739. 2019
  • Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice.  294:10392-10406. 2019
  • Mitochondrial localization, import, and mitochondrial function of the androgen receptor.  294:6621-6634. 2019
  • Identification and characterization of NanH2 and NanH3, enzymes responsible for sialidase activity in the vaginal bacterium Gardnerella vaginalis.  294:5230-5245. 2019
  • Correction: Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C ?-mediated zona occludens-1 phosphorylation at threonine 770/772 (Journal of Biological Chemistry (2014) 289 (3148-3163) DPO: 10.1074/jbc.M113.528190).  294:3311. 2019
  • The tuberculosis necrotizing toxin is an NAD and NADP glycohydrolase with distinct enzymatic properties.  294:3024-3036. 2019
  • Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex.  294:838-851. 2019
  • Retraction: Down-regulated peroxisome proliferator-activated receptor γ(PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD) (Journal of Biological Chemistry (2014) 289 (6383–6393) DOI: 10.1074/jbc.M113.536805).  294:69. 2019
  • Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly.  293:18828-18840. 2018
  • The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P2-binding site that targets Gag to the cell periphery.  293:18841-18853. 2018
  • Complement 1q-like-3 protein inhibits insulin secretion from pancreatic -cells via the cell adhesion G protein– coupled receptor BAI3.  293:18086-18098. 2018
  • Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.  293:17685-17704. 2018
  • CRISPR-delivery particles targeting nuclear receptor–interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.  293:17291-17305. 2018
  • Human interferon- and interferon- exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R.  293:16057-16068. 2018
  • IL-1R signaling promotes STAT3 and NF-B factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription.  293:15790-15800. 2018
  • Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds.  293:14659-14668. 2018
  • Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice.  293:6996-7007. 2018
  • The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1 signaling.  293:5659-5667. 2018
  • The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization.  293:4110-4121. 2018
  • ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor.  293:1610-1622. 2018
  • C/EBPα transcription factor is regulated by the RANK cytoplasmic 535IVVY538 motif and stimulates osteoclastogenesis more strongly than c-Fos..  293:1480-1492. 2018
  • Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.  293:1218-1228. 2018
  • Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation..  293:1218-1228. 2018
  • ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.  293:984-994. 2018
  • The microRNA-23a cluster regulates the developmental HoxA cluster function during osteoblast differentiation.  293:17646-17660. 2018
  • A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1..  292:20808-20817. 2017
  • Epigenetic modification of miR-663 controls mitochondriatonucleus retrograde signaling and tumor progression.  292:20694-20706. 2017
  • Constitutive role of the Fanconi anemia D2 gene in the replication stress response..  292:20184-20195. 2017
  • ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.  292:18924-18936. 2017
  • Hu antigen R (HuR) multimerization contributes to glioma disease progression.  292:16999-17010. 2017
  • Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.  292:14147-14164. 2017
  • The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand.  292:10390-10397. 2017
  • The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis.  292:5884-5897. 2017
  • The glycosyltransferase ST6Gal-I protects tumor cells against serum growth factor withdrawal by enhancing survival signaling and proliferative potential.  292:4663-4673. 2017
  • NADPH Oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway.  292:3029-3038. 2017
  • The interplay between calmodulin and membrane interactions with the pleckstrin homology domain of akt.  292:251-263. 2017
  • Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesin.  291:27354-27363. 2016
  • Altering the proteoglycan state of transforming growth factor β type III receptor (TβRIII)/betaglycan modulates canonical Wnt/β-catenin signaling.  291:25716-25728. 2016
  • Small molecule inhibition of the ubiquitin-specific protease USP2 accelerates cyclin D1 degradation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma models.  291:24628-24640. 2016
  • Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells.  291:24188-24199. 2016
  • Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β Group VIA phospholipase a2.  291:23268-23281. 2016
  • New helical binding domain mediates a glycosyltransferase activity of a bifunctional protein.  291:22106-22117. 2016
  • Human argonaute 2 is tethered to ribosomal RNA through MicroRNA interactions.  291:17919-17928. 2016
  • Correction: Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors. Evidence for the Role of Reactive Oxygen Species and JNK (Journal of Biological Chemistry (2011) 286 (5546-5557)).  291:16924. 2016
  • Correction: γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents (Journal of Biological Chemistry (2010) 285 (33520-33528)).  291:16922. 2016
  • CCAAT/enhancer-binding protein α (C/EBPα) is important for osteoclast differentiation and activity.  291:16390-16403. 2016
  • MYB promotes desmoplasia in pancreatic cancer through direct transcriptional up-regulation and cooperative action of sonic hedgehog and adrenomedullin.  291:16263-16270. 2016
  • Attenuation of PKR-like ER Kinase (PERK) signaling selectively controls endoplasmic reticulum stress-induced inflammation without compromising immunological responses.  291:15830-15840. 2016
  • Characterization of the interactions between calmodulin and death receptor 5 in triple-negative and estrogen receptor-positive breast cancer cells: An integrated experimental and computational study.  291:12862-12870. 2016
  • The stress-responsive gene ATF3 mediates dichotomous UV responses by regulating the Tip60 and p53 proteins.  291:10847-10857. 2016
  • The tumor-suppressive small GTPase DiRas1 binds the noncanonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases..  291:10948-10948. 2016
  • Regulation of Piezo2 mechanotransduction by static plasma membrane tension in primary afferent neurons.  291:9087-9104. 2016
  • Cytokines regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via distinct mechanisms and pathways.  291:8428-8439. 2016
  • The B3 subunit of the cone cyclic nucleotide-gated channel regulates the light responses of cones and contributes to the channel structural flexibility.  291:8721-8734. 2016
  • Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H2O2 Production.  291:6423-6432. 2016
  • Interaction between a domain of the negative regulator of the ras-ERK pathway, SPRED1 protein, and the GTPase-activating protein-related domain of neurofibromin is implicated in legius syndrome and neurofibromatosis type 1.  291:3124-3134. 2016
  • The transcription factor THO promotes transcription initiation and elongation by RNA Polymerase I.  291:3010-3018. 2016
  • Channel gating regulation by the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop.  291:1854-1865. 2016
  • Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions.  291:1652-1663. 2016
  • The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II..  291:1763-1773. 2016
  • Cytokine activation by antibody fragments targeted to cytokine-receptor signaling complexes.  291:447-461. 2016
  • Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions.  291:215-226. 2016
  • IL-1R/TLR2 through MyD88 divergently modulates osteoclastogenesis through regulation of nuclear factor of activated T cells c1 (NFATc1) and B lymphocyte-induced maturation protein-1 (Blimp1).  290:30163-30174. 2015
  • A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION..  290:29270-29280. 2015
  • Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein regulates the function of regulatory t cells.  290:28675-28682. 2015
  • Structural and biophysical characterization of the interactions between calmodulin and the pleckstrin homology domain of Akt.  290:27403-27413. 2015
  • Erratum: Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units (The Journal of Biological Chemistry (2013) 288 (25976-25985)).  290:26474-26475. 2015
  • Airway surface dehydration by transforming growth factor β (TGF-β) in cystic fibrosis is due to decreased function of a voltage-dependent potassium channel and can be rescued by the drug pirfenidone.  290:25710-25716. 2015
  • Metabolic reprogramming is required for myofibroblast contractility and differentiation.  290:25427-25438. 2015
  • Genome-wide mechanosensitive microRNA (MechanomiR) screen uncovers dysregulation of their regulatory networks in the mdm mouse model of muscular dystrophy.  290:24986-25011. 2015
  • The IVVY motif and tumor necrosis factor receptor-associated factor (TRAF) sites in the cytoplasmic domain of the receptor activator of nuclear factor κB (RANK) cooperate to induce osteoclastogenesis.  290:23738-23750. 2015
  • Regulation of ergothioneine biosynthesis and its effect on Mycobacterium tuberculosis growth and infectivity.  290:23064-23076. 2015
  • Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: A novel mechanism of tumor-host cross-talk.  290:941-949. 2015
  • Monocyte chemotactic protein-induced protein 1 and 4 form a complex but act independently in regulation of interleukin-6 mRNA degradation.  290:20782-20792. 2015
  • Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration.  290:19433-19444. 2015
  • Regulation of ERK kinase by MEK1 kinase inhibition in the brain.  290:16319-16329. 2015
  • Endoglin regulation of Smad2 function mediates beclin1 expression and endothelial autophagy.  290:14884-14892. 2015
  • Heterotrimeric Kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptors.  290:12765-12778. 2015
  • DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.  290:12068-12078. 2015
  • Group VIA phospholipase a2 (iPLA2β) modulates Bcl-x 5′-splice site selection and suppresses anti-apoptotic Bcl-x(L) in β-cells.  290:11021-11031. 2015
  • Transcriptional activity of the islet β cell factor Pdx1 Is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.  290:9812-9822. 2015
  • Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stage.  290:6890-6902. 2015
  • Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage.  290:6203-6214. 2015
  • The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages.  290:46-55. 2015
  • MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell.  289:36275-36283. 2014
  • Modulation of the mevalonate pathway by AKT regulates macrophage survival and development of pulmonary fibrosis.  289:36204-36219. 2014
  • Protein O-GlcNAcylation and cardiovascular (patho)physiology.  289:34449-34456. 2014
  • 3 Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophages.  289:33391-33403. 2014
  • Feedback induction of a photoreceptor-specific isoform of retinoid-related orphan nuclear receptor β by the rod transcription factor NRL.  289:32469-32480. 2014
  • The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage.  289:32883-32894. 2014
  • Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.  289:32937-32951. 2014
  • Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: Implications for amyotrophic lateral sclerosis.  289:31792-31804. 2014
  • Gli1 protein regulates the S-phase checkpoint in tumor cells via bid protein, and its inhibition sensitizes to DNA Topoisomerase 1 inhibitors.  289:31513-31525. 2014
  • An electrostatic interaction at the tetrahelix bundle promotes phosphorylation-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel opening.  289:30364-30378. 2014
  • Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle.  289:29397-29405. 2014
  • Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor..  289:27571-27584. 2014
  • Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis.  289:25486-25496. 2014
  • CRL4Cdt2 E3 ubiquitin ligase and Proliferating Cell Nuclear Antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.  289:23056-23064. 2014
  • The calcium-induced conformation and glycosylation of scavenger-rich cysteine repeat (SRCR) domains of glycoprotein 340 influence the high affinity interaction with antigen I/II homologs.  289:21877-21887. 2014
  • Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins.  289:20898-20907. 2014
  • Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs)..  289:19737-19746. 2014
  • Negative regulation of NADPH oxidase 4 by Hydrogen peroxide-inducible clone 5 (Hic-5) protein.  289:18270-18278. 2014
  • Mapping interactions between myosin relay and converter domains that power muscle function..  289:12779-12790. 2014
  • O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonicalwntsignaling.  289:12168-12176. 2014
  • Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.  289:11807-11815. 2014
  • Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells.  289:10466-10475. 2014
  • Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α.  289:8810-8817. 2014
  • Solution structure of calmodulin bound to the binding domain of the HIV-1 matrix protein.  289:8697-8705. 2014
  • Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding..  289:7948-7961. 2014
  • Down-regulated peroxisome proliferator-activated receptor γ (PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD).  289:6383-6393. 2014
  • Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.  289:5330-5339. 2014
  • Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-Hydroxyeicosatetraenoic acid partly via Protein Kinase C e-mediated Zona Occludens-1 Phosphorylation at Threonine 770/772.  289:3148-3163. 2014
  • Lipopolysaccharide-induced Lung Injury Involves the Nitration-mediated Activation of RhoA.  289:4710-4722. 2014
  • Increased ribozyme activity in crowded solutions.  289:2972-2977. 2014
  • Defining the communication between agonist and coactivator binding in the retinoid x receptor α ligand binding domain.  289:814-826. 2014
  • Conserved allosteric hot spots in the transmembrane domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channels and Multidrug Resistance Protein (MRP) pumps.  289:19942-19957. 2014
  • Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion.  289:25276-25286. 2014
  • The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling.  289:24691-24699. 2014
  • The retinaldehyde reductase activity of dhrs3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.  289:14868-14880. 2014
  • Transient receptor potential channel 6 (trpc6) protects podocytes during complement-Mediated glomerular disease.  288:36598-36609. 2013
  • MiR-125a-5p regulates differential activation of macrophages and inflammation.  288:35428-35436. 2013
  • Triptolide-induced cell death in Pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1.  288:33927-33938. 2013
  • The RclR protein is a reactive chlorine-specific transcription factor in escherichia coli.  288:32574-32584. 2013
  • Reduction of synaptojanin 1 accelerates aβ clearance and attenuates cognitive deterioration in an alzheimer mouse model.  288:32050-32063. 2013
  • Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.  288:30509-30514. 2013
  • MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-Mesenchymal transition (EMT) phenotype and are highly invasive in Vitro.  288:30000-30008. 2013
  • Secreted proteases control autolysin-mediated biofilm growth of staphylococcus aureus.  288:29440-29452. 2013
  • The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death.  288:29047-29055. 2013
  • Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release.  288:27128-27137. 2013
  • Discovery of streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units.  288:25976-25985. 2013
  • Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosis.  288:26013-26026. 2013
  • Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.  288:24560-24568. 2013
  • FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.  288:23194-23202. 2013
  • Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.  288:22248-22256. 2013
  • Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation.  288:22693-22705. 2013
  • Streptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units.  288:21945-21954. 2013
  • Structural and biophysical characterization of the interactions between the death domain of fas receptor and calmodulin.  288:21898-21908. 2013
  • An undesired effect of chemotherapy: Gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factorκb- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4.  288:21197-21207. 2013
  • Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages.  288:20745-20757. 2013
  • Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function.  288:18022-18034. 2013
  • P39, the primary activator for cyclin-dependent kinase 5 (CDK5) in oligodendroglia, is essential for oligodendroglia differentiation and myelin repair.  288:18047-18057. 2013
  • Converting nonhydrolyzable nucleotides to strong cystic fibrosis transmembrane conductance regulator (CFTR) agonists by gain of function (GOF) mutations.  288:17122-17133. 2013
  • A role for cargo in Arf-dependent adaptor recruitment.  288:14788-14804. 2013
  • Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy.  288:15194-15210. 2013
  • Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production.  288:14584-14598. 2013
  • NemR is a bleach-sensing transcription factor.  288:13789-13798. 2013
  • Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to smoothened-targeting Hedgehog inhibition.  288:11824-11833. 2013
  • Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins..  288:11325-11333. 2013
  • The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).  288:11532-11545. 2013
  • Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes.  288:10093-10099. 2013
  • BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycle.  288:8966-8976. 2013
  • DNA binding by the ribosomal DNA transcription factor Rrn3 is essential for ribosomal DNA transcription.  288:9135-9144. 2013
  • Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)..  288:9165-9176. 2013
  • Asymmetric dimethylarginine induces endothelial nitric-oxide synthase mitochondrial redistribution through the nitration-mediated activation of Akt1..  288:6212-6226. 2013
  • SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster..  288:5381-5388. 2013
  • Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdxl genes.  288:3795-3803. 2013
  • Structural arrangement of the intracellular Ca2+ binding domains of the cardiac Na+/Ca2+ exchanger (NCX1.1): Effects of Ca2+ binding.  288:4194-4207. 2013
  • Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonucleasethat translocates to the nucleus during apoptosis.  288:3460-3468. 2013
  • Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele.  288:2475-2484. 2013
  • Dynamin-mediated nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells (Journal of Biological Chemistry (2012) 287, (28932-28942)).  288:1277. 2013
  • Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly (ADP-ribose) polymerase-regulated DNAS1....  288:3460-3468. 2013
  • The enzymatic activity of apoptosis-inducing factor supports energy metabolism benefiting the growth and invasiveness of advanced prostate cancer cells..  287:43862-43875. 2012
  • miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.  287:42084-42092. 2012
  • Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma.  287:41288-41296. 2012
  • Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts.  287:40360-40370. 2012
  • Inhibition of histone deacetylase-induced myocardial repair is mediated by c-kit in infarcted hearts.  287:39338-39348. 2012
  • CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: Implications for bidirectional tumor-stromal interactions.  287:39115-39124. 2012
  • Modification of STIM1 by O-linked N-Acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes.  287:39094-39106. 2012
  • Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent.  287:34419-34431. 2012
  • Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease.  287:32459-32466. 2012
  • Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function.  287:32277-32287. 2012
  • Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.  287:30368-30375. 2012
  • p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.  287:30117-30127. 2012
  • Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.  287:28480-28494. 2012
  • Dynamin-mediated nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells.  287:28932-28942. 2012
  • Biochemical, genetic, and serological characterization of two capsule subtypes among Streptococcus pneumoniae serotype 20 strains: Discovery of a new pneumococcal serotype.  287:27885-27894. 2012
  • HMGN1 protein regulates poly(ADP-ribose) polymerase-1 (PARP-1) self-PARylation in mouse fibroblasts.  287:27648-27658. 2012
  • Epstein-barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties.  287:26586-26595. 2012
  • Targeting the sonic hedgehog pathway in keratocystic odontogenic tumor.  287:27117-27125. 2012
  • The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site.  287:24273-24283. 2012
  • Low temperature and chemical rescue affect molecular proximity of ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC).  287:16781-16790. 2012
  • Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis.  287:15728-15738. 2012
  • G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation..  287:13674-13685. 2012
  • Structural characterization of Streptococcus pneumoniae serotype 9A capsule polysaccharide reveals role of glycosyl 6-O-acetyltransferase wcjE in serotype 9V capsule biosynthesis and immunogenicity.  287:13996-14003. 2012
  • Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents (Journal of Biological Chemistry (2010) 285, (35406-35417)).  287:12152. 2012
  • Noggin is novel inducer of mesenchymal stem cell adipogenesis: Implications for bone health and obesity.  287:12241-12249. 2012
  • Heparan sulfate chains of syndecan-1 regulate ectodomain shedding.  287:9952-9961. 2012
  • Short chain dehydrogenase/reductase Rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development.  287:9061-9071. 2012
  • Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.  287:7990-8000. 2012
  • Latency-associated peptide of transforming growth factor-β1 is not subject to physiological mannose phosphorylation.  287:7526-7534. 2012
  • Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.  287:4107-4120. 2012
  • Glioma-specific cation conductance regulates migration and cell cycle progression.  287:4053-4065. 2012
  • Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.  287:3301-3312. 2012
  • Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells..  287:2459-2467. 2012
  • Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress.  23:10021-31. 2012
  • O-glcnacylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock.  286:44606-44619. 2011
  • Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway.  286:43370-43382. 2011
  • The structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes (The Journal of Biological Chemistry (2009) 284 (7318-7329)).  286:43588. 2011
  • Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "Rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.  286:41937-41948. 2011
  • γ-secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.  286:42514-42523. 2011
  • Phosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate kinase (MAGUK)..  286:41776-41785. 2011
  • The Unfolded Protein Response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes.  286:41862-41870. 2011
  • Identification of a novel Mcl-1 protein binding motif.  286:39829-39835. 2011
  • Loss of tumor suppressor merlin in advanced breast cancer is due to post-translational regulation.  286:40376-40385. 2011
  • Distinct functions of evolutionary conserved MSF1 and Late Embryogenesis Abundant (LEA)-like domains in mitochondria.  286:39141-39152. 2011
  • ST6Gal-I regulates macrophage apoptosis via α2-6 sialylation of the TNFR1 death receptor.  286:39654-39662. 2011
  • Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands.  286:38738-38747. 2011
  • Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation.  286:36898-36906. 2011
  • Comparative structural and molecular characterization of Streptococcus pneumoniae capsular polysaccharide serogroup 10.  286:35813-35822. 2011
  • A molecular chaperone mediates a two-protein enzyme complex and glycosylation of serine-rich streptococcal adhesins.  286:34923-34931. 2011
  • NMR, biophysical, and biochemical studies reveal the minimal calmodulin binding domain of the HIV-1 matrix protein.  286:33533-33543. 2011
  • Mining endonuclease cleavage determinants in genomic sequence data.  286:32617-32627. 2011
  • Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells.  286:32394-32403. 2011
  • Heparanase-mediated loss of nuclear syndecan-1 enhances Histone Acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype.  286:30377-30383. 2011
  • The SKP1-Cul1-F-box and leucine-rich repeat protein 4 (SCF-FbxL4) ubiquitin ligase regulates lysine demethylase 4A (KDM4A)/Jumonji domain-containing 2A (JMJD2A) protein.  286:30462-30470. 2011
  • Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities..  286:28435-28443. 2011
  • Structural and functional analysis of a new subfamily of glycosyltransferases required for glycosylation of serine-rich streptococcal adhesins.  286:27048-27057. 2011
  • Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions.  286:25963-25972. 2011
  • Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival.  286:26003-26015. 2011
  • Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-Extracellular Signal-regulated Kinase (ERK).  286:24776-24784. 2011
  • Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms.  286:24855-24864. 2011
  • TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-κB.  286:24159-24169. 2011
  • Sialylation of the Fas death receptor by St6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells.  286:22982-22990. 2011
  • Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.  286:22077-22089. 2011
  • Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains.  286:21657-21666. 2011
  • MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation.  286:19431-19438. 2011
  • Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin.  286:19100-19108. 2011
  • The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively.  286:18816-18824. 2011
  • Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly.  286:18825-18833. 2011
  • Alternative mitochondrial electron transfer as a novel strategy for neuroprotection.  286:16504-16515. 2011
  • Human papillomavirus (HPV) E7 induces prolonged G2 following S phase reentry in differentiated human keratinocytes.  286:15473-15482. 2011
  • Islet-1 regulates Arx transcription during pancreatic islet α-cell development.  286:15352-15360. 2011
  • Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation.  286:15597-15607. 2011
  • A unified view of cystic fibrosis transmembrane conductance regulator (CFTR) gating: Combining the allosterism of a ligand-gated channel with the enzymatic activity of an ATP-binding cassette (ABC) transporter.  286:12813-12819. 2011
  • Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture.  286:13550-13560. 2011
  • Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1.  286:12542-12553. 2011
  • Regulation of fatty acid metabolism by cell autonomous circadian clocks: Time to fatten up on information?.  286:11883-11889. 2011
  • Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis.  286:9612-9622. 2011
  • Dual functions of T-box 3 (Tbx3) in the control of self-renewal and extraembryonic endoderm differentiation in mouse embryonic stem cells.  286:8425-8436. 2011
  • Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes (Journal of Biological Chemistry (2009) 284 (7318-7329)).  286:8707. 2011
  • Regulation of histone H2A and H2B deubiquitination and xenopus development by USP12 and USP46.  286:7190-7201. 2011
  • Emerging role of α2,6-sialic acid as a negative regulator of galectin binding and function.  286:5935-5941. 2011
  • Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity.  286:6490-6499. 2011
  • Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-β production.  286:6117-6127. 2011
  • Ursolic acid, a pentacyclin triterpene, potentiates trail-induced apoptosis through p53-independent up-regulation of death receptors: Evidence for the role of reactive oxygen species and JNK.  286:5546-5557. 2011
  • Identification of nuclear localization, DNA binding, and transactivating mechanisms of krüppel-like zinc finger protein gli-similar 2 (Glis2).  286:4749-4759. 2011
  • Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response.  286:2559-2566. 2011
  • Lineage-specific effects of 1,25-dihydroxyvitamin D3 on the development of effector CD4 T cells.  286:997-1004. 2011
  • Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure.  285:41911-41920. 2010
  • Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain.  285:39759-39767. 2010
  • Structure of human Stabilin-1 Interacting Chitinase-Like Protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.  285:39898-39904. 2010
  • The ecto-enzyme CD38 is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) synthase that couples receptor activation to Ca2+ mobilization from lysosomes in pancreatic acinar cells.  285:38251-38259. 2010
  • Receptor activator of NF-κB (RANK) cytoplasmic IVVY535-538 motif plays an essential role in tumor necrosis factor-α (TNF)-mediated osteoclastogenesis.  285:37427-37435. 2010
  • Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2.  285:36586-36596. 2010
  • RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis.  285:36315-36321. 2010
  • Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.  285:35406-35417. 2010
  • The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes.  285:35599-35605. 2010
  • The cystic fibrosis-causing mutation ΔF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis.  285:35825-35835. 2010
  • Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.  285:33154-33164. 2010
  • γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents.  285:33520-33528. 2010
  • Structural insights into serine-rich fimbriae from gram-positive bacteria.  285:32446-32457. 2010
  • Characterization of the prion protein in human urine.  285:30489-30495. 2010
  • Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β.  285:29336-29347. 2010
  • A synonymous single nucleotide polymorphism in ΔF508 CFTR alters the secondary structure of the mRNA and the expression of the mutant protein.  285:28741-28748. 2010
  • Factor VIII and platelets synergistically accelerate cleavage of von Willebrand factor by ADAMTS13 under fluid shear stress.  285:28596-28603. 2010
  • Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain.  285:28708-28714. 2010
  • Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase.  285:27130-27143. 2010
  • DNAJB6 induces degradation of β-catenin and causes partial reversal of mesenchymal phenotype.  285:24686-24694. 2010
  • Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1.  285:25062-25073. 2010
  • Thy-1-integrin αvβ5 interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-β1 activation and myofibroblast differentiation.  285:22382-22393. 2010
  • Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.  285:21526-21536. 2010
  • Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.  285:20860-20869. 2010
  • What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.  285:19699-19704. 2010
  • Inflammation anergy in human intestinal macrophages is due to Smad-induced IκBα expression and NF-κB inactivation.  285:19593-19604. 2010
  • Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo.  285:16757-16770. 2010
  • Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells.  285:16476-16486. 2010
  • Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor β1-induced expression of plasminogen activator inhibitor 1 in fibroblasts.  285:16239-16247. 2010
  • Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice.  285:14521-14533. 2010
  • The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.  285:14152-14159. 2010
  • A novel glucosyltransferase is required for glycosylation of a serine-rich adhesin and biofilm formation by Streptococcus parasanguinis.  285:12140-12148. 2010
  • Lysosome dysfunction triggers Atg7-dependent neural apoptosis.  285:10497-10507. 2010
  • Amiloride docking to acid-sensing ion channel-1.  285:9627-9635. 2010
  • Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.  285:9716-9728. 2010
  • Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.  285:9322-9326. 2010
  • Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix.  285:7067-7078. 2010
  • Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A2 expression: A role for regulation by SREBP-1.  285:6693-6705. 2010
  • Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor α- and interleukin-1 β-induced IKK/NF-κB and JNK/AP-1 activation.  285:5347-5360. 2010
  • BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia.  285:5085-5096. 2010
  • Transforming growth factor β1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism.  285:4278-4290. 2010
  • Intracellular shuttling and mitochondrial function of thioredoxin- interacting protein.  285:3997-4005. 2010
  • Direct regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock.  285:2918-2929. 2010
  • Modulation of SCFβ-TrCP-dependent IκBα ubiquitination by hydrogen peroxide.  285:2665-2675. 2010
  • Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.  285:1743-1753. 2010
  • Branched-chain amino acid metabolon: Interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm).  285:265-276. 2010
  • Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.  284:36711-36719. 2009
  • Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation.  284:35283-35286. 2009
  • Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR). Implications for impaired post-transcriptional regulation of vascular endothelial growth factor.  284:33989-33998. 2009
  • The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.  284:34179-34188. 2009
  • Curcumin cross-links cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides and potentiates CFTR channel activity by distinct mechanisms.  284:30754-30765. 2009
  • Nutlin-3 affects expression and function of retinoblastoma protein. Role of Retinoblastoma protein in cellular response to nutlin-3.  284:26315-26321. 2009
  • Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo.  284:26085-26095. 2009
  • NDRG4 is required for cell cycle progression and survival in glioblastoma cells.  284:25160-25169. 2009
  • Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration.  284:24526-24541. 2009
  • Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.  284:23852-23859. 2009
  • The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.  284:22888-22897. 2009
  • S-glutathionylation of the Rpn2 regulatory subunit inhibits 26 S proteasomal function.  284:22213-22221. 2009
  • The 3′-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis.  284:22184-22194. 2009
  • A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage.  284:19280-19289. 2009
  • Psalmotoxin-1 docking to human acid-sensing ion channel-1.  284:17625-17633. 2009
  • Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells.  284:16898-16905. 2009
  • Turning cancer stem cells inside out: An exploration of glioma stem cells signalling pathways.  284:16705-16709. 2009
  • Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.  284:15676-15684. 2009
  • Myocyte enhancer factor 2 and microphthalmia-associated transcription factor cooperate with NFATc1 to transactivate the V-ATPase d2 promoter during RANKL-induced osteoclastogenesis.  284:14667-14675. 2009
  • Quantification of intermediates formed during the reduction of nitrite by deoxyhemoglobin.  284:12710-12718. 2009
  • A kinetic model for chain length modulation of Streptococcus pneumoniae cellubiuronan capsular polysaccharide by nucleotide sugar donor concentrations.  284:11836-11844. 2009
  • Characterization of the lipid linkage region and chain length of the cellubiuronic acid capsule of Streptococcus pneumoniae.  284:11826-11835. 2009
  • Molecular mechanism of the bifunctional role of lipopolysaccharide in osteoclastogenesis.  284:12512-12523. 2009
  • Cloning and characterization of Prisilkin-39, a novel matrix protein serving a dual role in the prismatic layer formation from the oyster Pinctada fucata.  284:10841-10854. 2009
  • Erratum: Mode of growth hormone action in osteoblasts (Journal of Biological Chemistry (2007) vol. 282 (31666-31674)).  284:10992. 2009
  • Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis.  284:10023-10033. 2009
  • Functions of the periplasmic loop of the porin MspA from Mycobacterium smegmatis.  284:10223-10231. 2009
  • Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury.  284:7853-7865. 2009
  • Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis Mouse model.  284:6885-6892. 2009
  • Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase.  284:7294-7306. 2009
  • Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes.  284:7318-7329. 2009
  • Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cγ and increase epithelial cell migration through indirect epidermal growth factor receptor activation.  284:6389-6402. 2009
  • Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathway.  284:5945-5955. 2009
  • Humanized mouse model of Cooley's anemia.  284:4889-4896. 2009
  • Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats).  284:3125-3135. 2009
  • Calcium-independent phospholipase A2 (iPLA2β)- mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis.  283:34819-34832. 2008
  • Effect of leucine to phenylalanine substitution on the nonpolar face of a class A amphipathic helical peptide on its interaction with lipid: High resolution solution NMR studies of 4F-dimyristoylphosphatidylcholine discoidal complex.  283:34393-34402. 2008
  • Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma.  283:32628-32636. 2008
  • Phospholipase Cγ2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.  283:29593-29601. 2008
  • Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling.  283:28354-28360. 2008
  • Modulation of the regulatory activity of bacterial two-component systems by SlyA.  283:28158-28168. 2008
  • Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure.  283:27767-27775. 2008
  • Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.  283:27585-27597. 2008
  • Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.  283:26839-26849. 2008
  • Proteolytic shedding of ST6Gal-I by BACE1 regulates the glycosylation and function of α4β1 integrins.  283:26364-26373. 2008
  • 15-Deoxy-Δ12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase.  283:24628-24640. 2008
  • Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB/PTEN suppression.  283:24889-24898. 2008
  • Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFκB and AP-1 activation as well as IL-6 gene expression.  283:24497-24505. 2008
  • G2E3 is a dual function ubiquitin ligase required for early embryonic development.  283:22304-22315. 2008
  • Sialylation of β1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis.  283:22177-22185. 2008
  • Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase.  283:20299-20308. 2008
  • Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signaling.  283:19359-19370. 2008
  • Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon.  283:18032-18039. 2008
  • Rv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteins.  283:17827-17837. 2008
  • NF-κB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway.  283:16391-16399. 2008
  • Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2.  283:15789-15798. 2008
  • Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling.  283:15319-15327. 2008
  • The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response.  283:12154-12165. 2008
  • Constitutive production of NF-κB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.  283:10698-10706. 2008
  • Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.  283:8412-8422. 2008
  • Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.  283:7438-7444. 2008
  • Human Cdt1 lacking the evolutionarily conserved region that interacts with MCM2-7 is capable of inducing re-replication.  283:6817-6825. 2008
  • Mutation of Gly721 alters DNA topoisomerase I active site architecture and sensitivity to camptothecin.  283:3305-3315. 2008
  • Cystic fibrosis transmembrane conductance regulator trafficking is mediated by the COPI coat in epithelial cells.  283:833-839. 2008
  • Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG.  283:638-647. 2008
  • A role for the transcriptional coactivator PGC-1α in muscle refueling.  282:36642-36651. 2007
  • Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer.  282:36481-36488. 2007
  • Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12.  282:35621-35628. 2007
  • Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.  282:35318-35327. 2007
  • Microtubule motors regulate ISOC activation necessary to increase endothelial cell permeability.  282:34801-34808. 2007
  • Participation of the chaperone Hsc70 in the trafficking and functional expression of ASIC2 in glioma cells.  282:34381-34391. 2007
  • Mode of growth hormone action in osteoblasts.  282:31666-31674. 2007
  • NR4A orphan nuclear receptors modulate insulin action and the glucose transport system: Potential role in insulin resistance.  282:31525-31533. 2007
  • ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.  282:30357-30362. 2007
  • Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells.  282:28597-28608. 2007
  • Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.  282:27100-27114. 2007
  • Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.  282:25649-25658. 2007
  • Heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits.  282:25548-25559. 2007
  • FadA from Fusobacterium nucleatum utilizes both secreted and nonsecreted forms for functional oligomerization for attachment and invasion of host cells.  282:25000-25009. 2007
  • Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2.  282:22448-22459. 2007
  • Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6.  282:22460-22471. 2007
  • The transition to an elongation complex by T7 RNA polymerase is a multistep process.  282:22879-22886. 2007
  • The Enterococcus faecalis MSCRAMM ace binds its ligand by the collagen hug model.  282:19629-19637. 2007
  • c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages..  282:18980-18990. 2007
  • Learning-induced glutamate receptor phosphorylation resembles that induced by long term potentiation.  282:18100-18107. 2007
  • Tumor necrosis factor-α stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression.  282:17450-17459. 2007
  • Identification of a HoxA10 activation domain necessary for transcription of the gene encoding β3 integrin during myeloid differentiation.  282:16846-16859. 2007
  • Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.  282:16511-16520. 2007
  • Erratum: A cysteine-scanning mutagenesis study of transmembrane domain 8 of the electrogenic sodium/bicarbonate cotransporter NBCe1 (Journal of Biological Chemistry (2006) 281 (32417-32427)).  282:15940. 2007
  • Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: Importance of vicinal cysteines 504 and 505.  282:14403-14412. 2007
  • Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn.  282:13736-13745. 2007
  • Heparanase enhances syndecan-1 shedding: A novel mechanism for stimulation of tumor growth and metastasis.  282:13326-13333. 2007
  • N-MYC regulates focal adhesion kinase expression in human neuroblastoma.  282:12503-12516. 2007
  • A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex.  282:11893-11903. 2007
  • Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality.  282:9855-9864. 2007
  • JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells.  282:6875-6886. 2007
  • Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 Cells by tyrosine-containing peptides.  282:6324-6337. 2007
  • Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the nucleotide-binding domains.  282:4533-4544. 2007
  • H2O2-induced kinetic and chemical modifications of smooth muscle myosin: Correlation to effects of H2O2 on airway smooth muscle.  282:4336-4344. 2007
  • The effect of class A scavenger receptor deficiency in bone.  282:4653-4660. 2007
  • ApoA-I mimetic peptides with differing ability to inhibit atherosclerosis also exhibit differences in their interactions with membrane bilayers.  282:1980-1988. 2007
  • Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation.  282:1687-1694. 2007
  • Concerted action of exonuclease and gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG) n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments.  282:3465-3477. 2007
  • Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.  282:4035-4044. 2007
  • The platelet-derived growth factor receptor α is destabilized by geldanamycins in cancer cells.  282:445-453. 2007
  • BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.  281:40515-40526. 2006
  • BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.  281:40515-40526. 2006
  • Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells.  281:39819-39830. 2006
  • Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G 1 cell cycle arrest.  281:39480-39491. 2006
  • Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses.  281:38854-38866. 2006
  • NF-κB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells.  281:38617-38624. 2006
  • SNARE status regulates tether recruitment and function in homotypic COPII vesicle fusion.  281:38825-38833. 2006
  • Interregulation of proton-gated Na+ channel 3 and cystic fibrosis transmembrane conductance regulator.  281:36960-36968. 2006
  • Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators.  281:35686-35698. 2006
  • Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.  281:35088-35096. 2006
  • Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner.  281:34696-34704. 2006
  • Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-β.  281:33971-33981. 2006
  • A cysteine-scanning mutagenesis study of transmembrane domain 8 of the electrogenic sodium/bicarbonate cotransporter NBCe1.  281:32417-32427. 2006
  • Function of the two xenopus Smad4s in early frog development.  281:30794-30803. 2006
  • Pescadillo interacts with the cadmium response element of the human heme oxygenase-1 promoter in renal epithelial cells.  281:24423-24430. 2006
  • Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C.  281:24322-24335. 2006
  • The circadian clock within the cardiomyocyte is essential for responsiveness of the heart to fatty acids.  281:24254-24269. 2006
  • Role of Bmi1 in H2A ubiquitylation and Hox gene silencing.  281:22537-22544. 2006
  • Insulin reverses growth hormone-induced homologous desensitization.  281:21594-21606. 2006
  • Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.  281:20958-20973. 2006
  • Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-deficient mice.  281:19000-19008. 2006
  • Role of protein-tyrosine phosphatase SHP2 in focal adhesion kinase down-regulation during neutrophil cathepsin G-induced cardiomyocytes anoikis.  281:19781-19792. 2006
  • Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells.  281:19220-19232. 2006
  • Nox1-dependent reactive oxygen generation is regulated by Rac1.  281:17718-17726. 2006
  • Apoptosis induction by activator protein 2α involves transcriptional repression of Bcl-2.  281:16207-16219. 2006
  • Differential binding of erythroid krupple-like factor to embryonic/fetal globin gene promoters during development.  281:16052-16057. 2006
  • Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.  281:15763-15773. 2006
  • Parkin Protects against Mitochondrial Toxins and β-Amyloid Accumulation in Skeletal Muscle Cells.  281:12809-12816. 2006
  • Regulation of surface localization of the small conductance Ca 2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase.  281:11769-11779. 2006
  • T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects.  281:11992-12000. 2006
  • Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione.  281:9190-9199. 2006
  • 9-O-acetylation of exogenously added ganglioside GD3: The GD3 molecule induces its own O-acetylation machinery.  281:7825-7833. 2006
  • δ-subunit confers novel biophysical features to αβγ- human epithelial sodium channel (ENaC) via a physical interaction.  281:8233-8241. 2006
  • Association of a model class A (apolipoprotein) amphipathic α helical peptide with lipid: High resolution NMR studies of peptide-lipid discoidal complexes.  281:6511-6519. 2006
  • PCNA is a cofactor for CDT1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination.  281:6246-6252. 2006
  • Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation.  281:6253-6260. 2006
  • Role of the carbohydrate binding site of the Streptococcus pneumoniae capsular polysaccharide type 3 synthase in the transition from oligosaccharide to polysaccharide synthesis.  281:6283-6289. 2006
  • The carboxyl terminus of the α-subunit of the amiloride-sensitive epithelial sodium channel binds to F-actin.  281:6528-6538. 2006
  • Hemoglobin is expressed by alveolar epithelial cells.  281:5668-5676. 2006
  • Topology of the porin MspA in the outer membrane of Mycobacterium smegmatis.  281:5908-5915. 2006
  • A novel receptor activator of NF-κB (RANK) cytoplasmic motif plays an essential role in osteoclastogenesis by committing macrophages to the osteoclast lineage.  281:4678-4690. 2006
  • Chronic wasting disease of elk and deer and Creutzfeldt-Jakob disease: Comparative analysis of the scrapie prion protein.  281:4199-4206. 2006
  • The histone acetyltransferase NCOAT contains a zinc finger-like motif involved in substrate recognition.  281:3918-3925. 2006
  • Mutations in the amino terminus of the cystic fibrosis transmembrane conductance regulator enhance endocytosis.  281:3329-3334. 2006
  • Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1.  281:3604-3613. 2006
  • Regulation through the RNA polymerase secondary channel: Structural and functional variability of the coiled-coil transcription factors.  281:1309-1312. 2006
  • Insulin enhances growth hormone induction of the MEK/ERK signaling pathway.  281:982-992. 2006
  • Effects of stable suppression of group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.  281:187-198. 2006
  • Evidence that the 11 β-hydroxysteroid dehydrogenase (11 β-HSD1) is regulated by pentose pathway flux: Studies in rat adipocytes and microsomes.  281:341-347. 2006
  • Receptor activator of NF-κB (RANK) cytoplasmic motif, 369PFQEP373, plays a predominant role in osteoclast survival in part by activating Akt/PKB and its downstream effector AFX/FOXO4.  280:43064-43072. 2005
  • Fatty acid transduction of nitric oxide signaling: Multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.  280:42464-42475. 2005
  • HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo.  280:40066-40073. 2005
  • The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia.  280:40097-40103. 2005
  • A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering β1 integrin sialylation.  280:37610-37615. 2005
  • Docking and rolling, a model of how the mitotic motor Eg5 works.  280:35684-35695. 2005
  • WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism.  280:34218-34223. 2005
  • Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.  280:33132-33140. 2005
  • The Gαo/i-coupled cannabinoid receptor-mediated neurite outgrowth involves rap regulation of Src and Stat3.  280:33426-33434. 2005
  • Dentin sialoprotein and dentin phosphoprotein overexpression during amelogenesis.  280:31991-31998. 2005
  • Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.  280:31859-31869. 2005
  • The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry..  280:31126-31131. 2005
  • Differential regulation of dentin sialophosphoprotein expression by Runx2 during odontoblast cytodifferentiation..  280:29717-29727. 2005
  • The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor.  280:29428-29434. 2005
  • Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation.  280:27624-27630. 2005
  • Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-α-positive breast cancer cells.  280:27022-27028. 2005
  • Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs.  280:23622-23630. 2005
  • Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage.  280:23566-23575. 2005
  • Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1.  280:24227-24237. 2005
  • Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase.  280:23416-23423. 2005
  • Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: Cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.  280:23173-23183. 2005
  • Blue light induces mitochondrial DNA damage and free radical production in epithelial cells.  280:21061-21066. 2005
  • Oxysterols inhibit phosphatidylcholine synthesis via ERK docking and phosphorylation of CTP:phosphocholine cytidylyltransferase.  280:21577-21587. 2005
  • The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor.  280:21264-21271. 2005
  • The C-terminal sterile α motif and the extreme C terminus regulate the transcriptional activity of the α isoform of p73.  280:20111-20119. 2005
  • Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation Fourier transform-ion cyclotron resonance mass spectrometry.  280:19136-19145. 2005
  • Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor.  280:19289-19297. 2005
  • Growth hormone receptor is a target for presenilin-dependent γ-secretase cleavage.  280:19331-19342. 2005
  • Interleukin-1β decreases expression of the epithelial sodium channel α-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway.  280:18579-18589. 2005
  • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation.  280:16635-16641. 2005
  • Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation.  280:15872-15879. 2005
  • Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils.  280:14579-14585. 2005
  • Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through Gαo/i-triggered proteasomal degradation of Rap1GAPII.  280:11413-11421. 2005
  • The small heat shock protein αB-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.  280:11059-11066. 2005
  • Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: A role of RDH11 in visual processes in vivo.  280:8694-8704. 2005
  • Linking of N-Myc to death receptor machinery in neuroblastoma cells.  280:9474-9481. 2005
  • Calmodulin and calmodulin-dependent kinase IIα regulate osteoblast differentiation by controlling c-fos expression.  280:7049-7059. 2005
  • Cellular checkpoint mechanisms monitoring proper initiation of DNA replication.  280:6253-6256. 2005
  • Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIβ expressed in pancreatic islet β-cells.  280:6840-6849. 2005
  • Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level.  280:5750-5763. 2005
  • Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells.  280:3780-3788. 2005
  • Identification of an invasion regulatory domain within the core protein of syndecan-1.  280:3467-3473. 2005
  • The adaptor protein HSH2 attenuates apoptosis in response to ligation of the B cell antigen receptor complex on the B lymphoma cell line, WEHI-231.  280:3507-3515. 2005
  • EVI1 abrogates interferon-α response by selectively blocking PML induction.  280:428-436. 2005
  • Functional identification of three receptor activator of NF-κB cytoplasmic motifs mediating osteoclast differentiation and function.  279:54759-54769. 2004
  • Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin.  279:54502-54509. 2004
  • Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.  279:54069-54078. 2004
  • Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.  279:53665-53673. 2004
  • Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function.  279:53435-53441. 2004
  • Two homologous apolipoprotein AI mimetic peptides: Relationship between membrane interactions and biological activity.  279:51404-51414. 2004
  • Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids.  279:49931-49939. 2004
  • Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly.  279:48983-48992. 2004
  • The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-β complex.  279:47633-47642. 2004
  • Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene.  279:46326-46334. 2004
  • Neutrophils exhibit rapid agonist-induced increases in protein-associated O-GlcNAc.  279:45759-45765. 2004
  • Intranuclear trafficking: Organization and assembly of regulatory machinery for combinatorial biological control.  279:43363-43366. 2004
  • The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain.  279:43581-43588. 2004
  • Regulation of the cell type-specific dentin sialophosphoprotein gene expression in mouse odontoblasts by a novel transcription repressor and an activator CCAAT-binding factor.  279:42182-42191. 2004
  • Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle.  279:39593-39603. 2004
  • Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression.  279:38577-38589. 2004
  • Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase.  279:38087-38090. 2004
  • Male mice that do not express Group VIA Phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.  279:38194-38200. 2004
  • The Ca2+ homeostasis defects in a pgm2Δ strain of Saccharomyces cerevisiae are caused by excessive vacuolar Ca2+ uptake mediated by the Ca2+-ATPase Pmc1p.  279:38495-38502. 2004
  • Anchoring of surface proteins to the cell wall of Staphylococcus aureus: A conserved arginine residue is required for efficient catalysis of sortase A.  279:37763-37770. 2004
  • Molecular interactions that confer latency to transforming growth factor-β.  279:38032-38039. 2004
  • Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-β activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2.  279:34311-34322. 2004
  • Nox3 regulation by NOXO1, p47phox, and p67phox.  279:34250-34255. 2004
  • Steroids and exogenous γ-ENaC subunit modulate cation channels formed by α-ENaC in human B lymphocytes.  279:33206-33212. 2004
  • Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.  279:32771-32779. 2004
  • Crystal structures of Staphylococcus aureus Sortase A and its substrate complex.  279:31383-31389. 2004
  • Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium.  279:30945-30953. 2004
  • Phosphorylation of mouse glutamine-fructose-6-phosphate amidotransferase 2 (GFAT2) by cAMP-dependent protein kinase increases the enzyme activity.  279:29988-29993. 2004
  • A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.  279:27518-27524. 2004
  • Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux.  279:25966-25977. 2004
  • Aromatic residue position on the nonpolar face of class A amphipathic helical peptides determines biological activity.  279:26509-26517. 2004
  • Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation.  279:23510-23516. 2004
  • Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines.  279:22578-22584. 2004
  • Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity.  279:22092-22101. 2004
  • Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: Impact on growth hormone signaling.  279:20898-20905. 2004
  • Evidence that the TM1-TM2 loop contributes to the ρ1 GABA receptor pore.  279:20906-20914. 2004
  • The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons.  279:21271-21281. 2004
  • A Redox-controlled Molecular Switch Revealed by the Crystal Structure of a Bacterial Heme PAS Sensor.  279:20186-20193. 2004
  • Characterization of Na+-permeable Cation Channels in LLC-PK1 Renal Epithelial Cells.  279:20137-20146. 2004
  • Functional analysis of the rod photoreceptor cGMP phosphodiesterase α-subunit gene promoter: Nrl and Crx are required for full transcriptional activity.  279:19800-19807. 2004
  • Selective Deficiency of the "Bone-related" Runx2-II Unexpectedly Preserves Osteoblast-mediated Skeletogenesis.  279:20307-20313. 2004
  • Intercellular Adhesion Molecule-1 (ICAM-1) Regulates Endothelial Cell Motility through a Nitric Oxide-dependent Pathway.  279:19230-19238. 2004
  • Extracellular ATP-mediated Signaling for Survival in Hyperoxia-induced Oxidative Stress.  279:16317-16325. 2004
  • PIKE (Phosphatidylinositol 3-Kinase Enhancer)-A GTPase Stimulates Akt Activity and Mediates Cellular Invasion.  279:16441-16451. 2004
  • Cyclic AMP activation of the extracellular signal-regulated kinases 1 and 2: Implications for intestinal cell survival through the transient inhibition of apoptosis.  279:14828-14834. 2004
  • Homocysteine Increases the Expression of Vascular Endothelial Growth Factor by a Mechanism Involving Endoplasmic Reticulum Stress and Transcription Factor ATF4.  279:14844-14852. 2004
  • Smad4 Protein Stability Is Regulated by Ubiquitin Ligase SCF β-TrCP1.  279:14484-14487. 2004
  • Deletion of Dentin Matrix Protein-1 Leads to a Partial Failure of Maturation of Predentin into Dentin, Hypomineralization, and Expanded Cavities of Pulp and Root Canal during Postnatal Tooth Development.  279:19141-19148. 2004
  • Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice.  279:18614-18622. 2004
  • Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase: Evolutionary conservation of product inhibition.  279:12769-12776. 2004
  • Molecules Mimicking Smad1 Interacting with Hox Stimulate Bone Formation.  279:11313-11319. 2004
  • Extracellular Zinc and ATP Restore Chloride Secretion across Cystic Fibrosis Airway Epithelia by Triggering Calcium Entry.  279:10720-10729. 2004
  • Amphetamine regulation of dopamine transport: Combined measurements of transporter currents and transporter imaging support the endocytosis of an active carrier.  279:8966-8975. 2004
  • Evolutionary Trace of G Protein-coupled Receptors Reveals Clusters of Residues That Determine Global and Class-specific Functions.  279:8126-8132. 2004
  • Heparanase degrades syndecan-1 and perlecan heparan sulfate: Functional implications for tumor cell invasion.  279:8047-8055. 2004
  • Relationship between growth rate and ATP concentration in escherichia coli: A bioassay for available cellular ATP.  279:8262-8268. 2004
  • Resistance of mitochondrial DNA-depleted cells against cell death: Role of mitochondrial superoxide dismutase.  279:7512-7520. 2004
  • The Role of Pre-H2 Domains of α- and δ-Epithelial Na + Channels in Ion Permeation, Conductance, and Amiloride Sensitivity.  279:8428-8440. 2004
  • Calmodulin binding to the Fas death domain: Regulation by Fas activation.  279:5661-5666. 2004
  • NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain.  279:4737-4742. 2004
  • Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines.  279:3662-3670. 2004
  • Selective Disruption of Lysosomes in HeLa Cells Triggers Apoptosis Mediated by Cleavage of Bid by Multiple Papain-like Lysosomal Cathepsins.  279:3578-3587. 2004
  • Transcription Factor B Contacts Promoter DNA Near the Transcription Start Site of the Archaeal Transcription Initiation Complex.  279:2825-2831. 2004
  • Breast Cancer Metastasis Suppressor 1 (BRMS1) Forms Complexes with Retinoblastoma-binding Protein 1 (RBP1) and the mSin3 Histone Deacetylase Complex and Represses Transcription.  279:1562-1569. 2004
  • Mutation of CpGs in the Murine Stem Cell Virus Retroviral Vector Long Terminal Repeat Represses Silencing in Embryonic Stem Cells.  279:34-41. 2004
  • Cell Cycle Arrest and Apoptosis Induction by Activator Protein 2α (AP-2α) and the Role of p53 and p21WAF1/CIP1 in AP-2α-mediated Growth Inhibition.  278:52093-52101. 2003
  • Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin.  278:53035-53044. 2003
  • Function of γ-Aminobutyric Acid Receptor/Channel ρ1 Subunits in Spinal Cord.  278:48321-48329. 2003
  • Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction.  278:46349-46356. 2003
  • Cleavage of the ADAMTS13 Propeptide Is Not Required for Protease Activity.  278:46643-46648. 2003
  • Vitamin D Inhibits G1 to S Progression in LNCaP Prostate Cancer Cells through p27Kip1 Stabilization and Cdk2 Mislocalization to the Cytoplasm.  278:46862-46868. 2003
  • The Extracellular Domain Determines the Kinetics of Desensitization in Acid-sensitive Ion Channel 1.  278:45240-45247. 2003
  • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells.  278:44312-44319. 2003
  • Transforming Growth Factor-β1 Decreases Expression of the Epithelial Sodium Channel αENaC and Alveolar Epithelial Vectorial Sodium and Fluid Transport via an ERK1/2-dependent Mechanism.  278:43939-43950. 2003
  • p21-dependent Inhibition of Colon Cancer Cell Growth by Mevastatin Is Independent of Inhibition of G1 Cyclin-dependent Kinases.  278:43586-43594. 2003
  • JUMONJI, a Critical Factor for Cardiac Development, Functions as a Transcriptional Repressor.  278:42247-42255. 2003
  • Cytosolic Arl2 Is Complexed with Cofactor D and Protein Phosphatase 2A.  278:40829-40836. 2003
  • Evidence for an Intracellular ADP-ribosyl Cyclase/NAD +-glycohydrolase in Brain from CD38-deficient Mice.  278:40670-40678. 2003
  • Identification of Novel Proteinase K-resistant C-terminal Fragments of PrP in Creutzfeldt-Jakob Disease.  278:40429-40436. 2003
  • Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons.  278:43628-43635. 2003
  • Rapid tau aggregation and delayed hippocampal neuronal death induced by persistent thrombin signaling.  278:37681-37689. 2003
  • LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: Implications in prostate cancer.  278:36868-36875. 2003
  • A biochemical characterization of the adeno-associated virus Rep40 helicase..  278:34011-34017. 2003
  • Mice lacking phosphatidylinositol transfer protein-α exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia.  278:33501-33518. 2003
  • Control of mitochondrial respiration by NO., Effects of low oxygen and respiratory state.  278:31603-31609. 2003
  • Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13.  278:30136-30141. 2003
  • Genomic expression discovery predicts pathways and opposing functions behind phenotypes.  278:23830-23833. 2003
  • Reversible inhibition of cytochrome c oxidase by peroxynitrite proceeds through ascorbate-dependent generation of nitric oxide.  278:27520-27524. 2003
  • Sumoylation of Smad4, the common Smad mediator of transforming growth factor-β family signaling.  278:27853-27863. 2003
  • Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation..  278:20603-20611. 2003
  • Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells: Modulation of EGF-induced trafficking and signaling.  278:18902-18913. 2003
  • Stepping and stretching. How kinesin uses internal strain to walk processively..  278:18550-18556. 2003
  • The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer.  278:18235-18240. 2003
  • The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.  278:17557-17565. 2003
  • Acid-sensing ion channels in malignant gliomas.  278:15023-15034. 2003
  • Smad4 as a transcription corepressor for estrogen receptor α.  278:15192-15200. 2003
  • Direct binding of syndecan-4 cytoplasmic domain to the catalytic domain of protein kinase Cα (PKCα) increases focal adhesion localization of PKCα.  278:13795-13802. 2003
  • Heparan sulfate regulates targeting of syndecan-1 to a functional domain on the cell surface.  278:12888-12893. 2003
  • Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine.  278:13143-13150. 2003
  • Sustained calcium entry through P2X nucleotide receptor channels in human airway epithelial cells.  278:13398-13408. 2003
  • Amphetamine-induced dopamine efflux: A voltage-sensitive and intracellular Na+-dependent mechanism.  278:12070-12077. 2003
  • The core of the tetrameric mycobacterial porin MspA is an extremely stable β-sheet domain.  278:8678-8685. 2003
  • Inhibition of cdk2 activating phosphorylation by mevastatin.  278:4840-4846. 2003
  • A novel active DNA topoisomerase I in Leishmania donovani.  278:3521-3526. 2003
  • Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2.  278:4135-4144. 2003
  • Nitric oxide-dependent generation of reactive species in sickle cell disease: Actin tyrosine nitration induces defective cytoskeletal polymerization.  278:4194-4204. 2003
  • Metalloprotease-mediated GH receptor proteolysis and GHBP shedding: Determination of extracellular domain stem region cleavage site.  277:50510-50519. 2002
  • Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression.  277:49952-49957. 2002
  • Regulation of inositol phospholipid binding and signaling through syndecan-4.  277:49296-49303. 2002
  • Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain.  277:48596-48601. 2002
  • Insulin signal transduction pathways and insulin-induced gene expression.  277:48565-48573. 2002
  • Conserved residues in the putative catalytic triad of human bile acid coenzyme A:Amino acid N-acyltransferase.  277:47270-47275. 2002
  • Intracellular glucose 1-phosphate and glucose 6-phosphate levels modulate Ca2+ homeostasis in Saccharomyces cerevisiae.  277:45751-45758. 2002
  • Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function.  277:45734-45740. 2002
  • Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth: Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor.  277:44638-44650. 2002
  • Reactive oxygen nitrogen species decrease cystic fibrosis transmembrane conductance regulator expression and cAMP-mediated Cl- secretion in airway epithelia.  277:43041-43049. 2002
  • The CY domain of the FcγRIa α-chain (CD64) alters γ-chain tyrosine-based signaling and phagocytosis.  277:41287-41293. 2002
  • PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator.  277:40099-40105. 2002
  • A gnotobiotic transgenic mouse model for studying interactions between small intestinal enterocytes and intraepithelial lymphocytes.  277:37811-37819. 2002
  • A tetrameric porin limits the cell wall permeability of Mycobacterium smegmatis.  277:37567-37572. 2002
  • CD40-mediated activation of NF-κB in airway epithelial cells.  277:37054-37063. 2002
  • The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin.  277:37219-37228. 2002
  • p38 and activating transcription factor-2 involvement in osteoblast osmotic response to elevated extracellular glucose.  277:37212-37218. 2002
  • Measuring kinesin's first step.  277:36731-36739. 2002
  • Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts.  277:33632-33640. 2002
  • Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors.  277:32830-32836. 2002
  • Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA.  277:32992-33000. 2002
  • RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor.  277:32379-32388. 2002
  • Identification of Glis1, a novel Gli-related, Krüppel-like zinc finger protein containing transactivation and repressor functions.  277:30901-30913. 2002
  • Evidence that the human gene for prostate short-chain dehydrogenase/ reductase (PSDR1) encodes a novel retinal reductase (RalR1).  277:28909-28915. 2002
  • Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation.  277:28384-28393. 2002
  • Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer.  277:25431-25438. 2002
  • c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.  277:23065-23075. 2002
  • Thrombospondin stimulates focal adhesion disassembly through Gi- and phosphoinositide 3-kinase-dependent ERK activation.  277:20453-20460. 2002
  • Mutual dependence of MDM2 and MDMX in their functional inactivation of p53.  277:19251-19254. 2002
  • Specific modification of mitochondrial protein thiols in response to oxidative stress. A proteomics approach.  277:17048-17056. 2002
  • The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes.  277:17271-17280. 2002
  • Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes.  277:14266-14273. 2002
  • Critical role of tumor necrosis factor-α and NF-κB in interferon-γ-induced CD40 expression in microglia/macrophages.  277:13796-13803. 2002
  • Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis.  277:10139-10149. 2002
  • Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-β activation in mesangial cells.  277:9880-9888. 2002
  • Regulation of the murine Nfatc1 gene by NFATc2.  277:10704-10711. 2002
  • Characterization of murine sphingosine-1-phosphate phosphohydrolase..  277:8920-8927. 2002
  • Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC).  277:7641-7644. 2002
  • Hydrostatic pressure induces the fusion-active state of enveloped viruses.  277:8433-8439. 2002
  • Up-regulation of acid-gated Na+ channels (ASICs) by cystic fibrosis transmembrane conductance regulator co-expression in Xenopus oocytes.  277:8395-8405. 2002
  • A T cell-specific enhancer of the human CD40 ligand gene.  277:7386-7395. 2002
  • Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells.  277:6858-6863. 2002
  • Interleukin-4 reversibly inhibits osteoclastogenesis via inhibition of NF-κB and mitogen-activated protein kinase signaling.  277:6622-6630. 2002
  • Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin.  277:3813-3822. 2002
  • The serine protease trypsin cleaves C termini of β- and γ-subunits of epithelial Na+ channels.  277:4134-4140. 2002
  • Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response.  277:1933-1940. 2002
  • CCAAT/enhancer-binding proteins (C/EBP) β and δ activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.  277:1316-1323. 2002
  • Molecular cross-talk between the TRAIL and interferon signaling pathways.  277:575-585. 2002
  • Respiratory syncytial virus inhibits apoptosis and induces NF-κB activity through a phosphatidylinositol 3-kinase-dependent pathway.  277:492-501. 2002
  • Expression of the Streptococcus pneumoniae Type 3 Synthase in Escherichia coli: Assembly of type 3 polysaccharide on a lipid primer.  276:48831-48839. 2001
  • Structural basis for pterin antagonism in nitric-oxide synthase: Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin.  276:49133-49141. 2001
  • CpsB Is a Modulator of Capsule-associated Tyrosine Kinase Activity in Streptococcus pneumoniae.  276:47966-47974. 2001
  • Rab5-dependent Trafficking of the m4 Muscarinic Acetylcholine Receptor to the Plasma Membrane, Early Endosomes, and Multivesicular Bodies.  276:47590-47598. 2001
  • Reactivation of Peroxisome Proliferator-activated Receptor α Is Associated with Contractile Dysfunction in Hypertrophied Rat Heart.  276:44390-44395. 2001
  • Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureus.  276:44721-44728. 2001
  • Poly(A) Polymerase and the Regulation of Cytoplasmic Polyadenylation.  276:41810-41816. 2001
  • Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura.  276:41059-41063. 2001
  • ATP Reorients the Neck Linker of Kinesin in Two Sequential Steps.  276:40167-40174. 2001
  • pH Alterations "Reset" Ca2+ Sensitivity of Brain Na+ Channel 2, a Degenerin/Epithelial Na+ Ion Channel, in Planar Lipid Bilayers.  276:38755-38761. 2001
  • Identification of Two Topologically Independent Domains in RAG1 and Their Role in Macromolecular Interactions Relevant to V(D)J Recombination.  276:37093-37101. 2001
  • Novel Differences between Two Human Prion Strains Revealed by Two-dimensional Gel Electrophoresis.  276:37284-37288. 2001
  • Protein Synthesis-dependent and -independent Regulation of Hippocampal Synapses by Brain-derived Neurotrophic Factor.  276:37585-37593. 2001
  • Structure of pyruvate dehydrogenase kinase: Novel folding pattern for a serine protein kinase.  276:37443-37450. 2001
  • Saccharomyces cerevisiae Protein Pci8p and Human Protein eIF3e/Int-6 Interact with the eIF3 Core Complex by Binding to Cognate eIF3b Subunits.  276:34948-34957. 2001
  • The Absence of Activator Protein 1-dependent Gene Expression in THP-1 Macrophages Stimulated with Phorbol Esters Is Due to Lack of p38 Mitogen-activated Protein Kinase Activation.  276:33826-33832. 2001
  • Characterization of Selected Strains of Pneumococcal Surface Protein A.  276:33121-33128. 2001
  • Architecture of the Human Origin Recognition Complex.  276:29067-29071. 2001
  • Oncogenic Ras Represses Transforming Growth Factor-β/Smad Signaling by Degrading Tumor Suppressor Smad4.  276:29531-29537. 2001
  • L-Arginine Chlorination Products Inhibit Endothelial Nitric Oxide Production.  276:27159-27165. 2001
  • Multiple Mechanisms Regulate Subcellular Localization of Human CDC6.  276:26947-26954. 2001
  • Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase.  276:26486-26491. 2001
  • Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis.  276:24565-24573. 2001
  • ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors. Characterizing ARL1-binding proteins.  276:22826-22837. 2001
  • An Essential Role for Mad Homology Domain 1 in the Association of Smad3 with Histone Deacetylase Activity.  276:22595-22603. 2001
  • Characterization of a novel type of human microsomal 3α -hydroxysteroid dehydrogenase. Unique tissue distribution and catalytic properties.  276:22278-22286. 2001
  • Demonstration of Direct Effects of Growth Hormone on Neonatal Cardiomyocytes.  276:22892-22900. 2001
  • Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins.  276:18757-18764. 2001
  • Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling.  276:18908-18914. 2001
  • Rvb1p and Rvb2p are Essential Components of a Chromatin Remodeling Complex that Regulates Transcription of over 5% of Yeast Genes.  276:16279-16288. 2001
  • Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5.  276:14490-14497. 2001
  • Studies of Insulin Secretory Responses and of Arachidonic Acid Incorporation into Phospholipids of Stably Transfected Insulinoma Cells That Overexpress Group VIA Phospholipase A2 (iPLA2β) Indicate a Signaling Rather Than a Housekeeping Role for iPLA2β.  276:13198-13208. 2001
  • The Angiotensin II-dependent Nuclear Translocation of Stat1 is Mediated by the Jak2 Protein Motif 231YRFRR.  276:10556-10563. 2001
  • Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression..  276:10119-10125. 2001
  • Expression and Regulation of Normal and Polymorphic Epithelial Sodium Channel by Human Lymphocytes.  276:8557-8566. 2001
  • Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation.  276:6621-6630. 2001
  • Structural Transformations Accompanying the Assembly of Bacteriophage P22 Portal Protein Rings in Vitro.  276:6779-6788. 2001
  • Human Homolog of the MutY Repair Protein (hMYH) Physically Interacts with Proteins Involved in Long Patch DNA Base Excision Repair.  276:5547-5555. 2001
  • Crucial Role of the HIGH-loop Lysine for the Catalytic Activity of Arginyl-tRNA Synthetase.  276:3723-3726. 2001
  • The p115-interactive Proteins GM130 and Giantin Participate in Endoplasmic Reticulum-Golgi Traffic.  276:2693-2700. 2001
  • An Essential Role of Glu-243 and His-239 in the Phosphotransfer Reaction Catalyzed by Pyruvate Dehydrogenase Kinase.  276:17994-17999. 2001
  • A bipartite substrate recognition motif for cyclin-dependent kinases.  276:1993-1997. 2001
  • Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells.  276:915-923. 2001
  • Indirubins inhibit glycogen synthase kinase-3β and CDK5/P25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?.  276:251-260. 2001
  • Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-β in human renal epithelial cells.  275:40904-40909. 2000
  • Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-β-induced physical and functional interactions between Smads and Sp1.  275:40014-40019. 2000
  • Identification and characterization of two G protein-coupled receptors for neuropeptide FF..  275:39324-39331. 2000
  • Essential role for caspase-8 in transcription-independent apoptosis triggered by p53.  275:38905-38911. 2000
  • Reaction of S-nitrosoglutathione with the heme group of deoxyhemoglobin.  275:36562-36567. 2000
  • Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin.  275:36358-36368. 2000
  • Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling..  275:36400-36406. 2000
  • Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor.  275:35077-35085. 2000
  • Identification and characterization of the human ORC6 homolog.  275:34983-34988. 2000
  • Integrin activation and focal complex formation in cardiac hypertrophy.  275:35624-35630. 2000
  • Subsets of human origin recognition complex (ORC) subunits are expressed in non-proliferating cells and associate with non-ORC proteins.  275:35233-35241. 2000
  • A constitutive active MEK → ERK pathway negatively regulates NF-κB-dependent gene expression by modulating TATA-binding protein phosphorylation.  275:27858-27864. 2000
  • A rat kidney-specific calcium transporter in the distal nephron.  275:28186-28194. 2000
  • The cytosolic termini of the β- and γ-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel.  275:27947-27956. 2000
  • Biosynthesis of type 3 capsular polysaccharide in Streptococcus pneumoniae: Enzymatic chain release by an abortive translocation process.  275:25972-25978. 2000
  • Calcium influx factor directly activates store-operated cation channels in vascular smooth muscle cells.  275:26158-26163. 2000
  • Erratum: Design and analysis of an engineered human interleukin-10 monomer (Journal of Biological Chemistry (2000) 275 (13552-13557)).  275:25054. 2000
  • Involvement of STAT-1 and Ets family members interferon-γ induction of CD40 transcription in microglia/macrophages.  275:23674-23684. 2000
  • Phosphorylation of human glutamine:fructose-6-phosphate amidotransferase by cAMP-dependent protein kinase at serine 205 blocks the enzyme activity.  275:21981-21987. 2000
  • Concentration-dependent effects of nitric oxide on mitochondrial permeability transition and cytochrome c release.  275:20474-20479. 2000
  • Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic α-helix as a recognition motif.  275:18897-18904. 2000
  • Cyclic nucleotide-gated channels mediate membrane depolarization following activation of store-operated calcium entry in endothelial cells.  275:18887-18896. 2000
  • Electrospray ionization/mass spectrometric analyses of human promonocytic U937 cell glycerolipids and evidence that differentiation is associated with membrane lipid composition changes that facilitate phospholipase A2 activation.  275:16579-16589. 2000
  • Biochemical structural analysis of the lantibiotic mutacin II.  275:15845-15850. 2000
  • Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.  275:15246-15253. 2000
  • The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation.  275:14248-14254. 2000
  • Design and analysis of an engineered human interleukin-10 monomer.  275:13552-13557. 2000
  • Nitric oxide reaction with lipid peroxyl radicals spares α-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/α-tocopherol than α-tocopherol/ascorbate.  275:10812-10818. 2000
  • Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus.  275:10196-10201. 2000
  • Sp1/Sp3 and PU.1 differentially regulate beta(5) integrin gene expression in macrophages and osteoblasts..  275:8331-8340. 2000
  • HeLa cells are phenotypically limiting in cyclin E/CDK2 for efficient human papillomavirus DNA replication.  275:6167-6174. 2000
  • Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae.  275:5431-5440. 2000
  • Mechanism of type 3 capsular polysaccharide synthesis in Streptococcus pneumoniae.  275:3907-3914. 2000
  • De novo design of peptides targeted to the EF hands of calmodulin.  275:2676-2685. 2000
  • Mutational analysis of the primary substrate specificity pocket of complement factor B. Asp226 is a major structural determinant for P1-Arg binding.  275:378-385. 2000
  • Peptide inhibition of constitutively activated epithelial Na+ channels expressed in Xenopus oocytes.  274:37693-37704. 1999
  • Regulation of epithelial Na+ channels by actin in planar lipid bilayers and in the Xenopus oocyte expression system.  274:37845-37854. 1999
  • DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells.  274:37450-37454. 1999
  • Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts.  274:36015-86024. 1999
  • The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression.  274:35255-35261. 1999
  • Transcriptional regulation of Fas gene expression by GA-binding protein and AP-1 in T cell antigen receptor · CD3 complex-stimulated T cells.  274:35203-35210. 1999
  • Yeast SMF1 mediates H+-coupled iron uptake with concomitant uncoupled cation currents.  274:35089-35094. 1999
  • A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.  273:31731-31737. 1999
  • Molecular and functional characterization of a calcium-sensitive chloride channel from mouse lung.  273:32096-32101. 1999
  • Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing.  274:34396-34402. 1999
  • Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2αB/core binding factor α2.  274:33580-33586. 1999
  • A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn.  274:33131-33142. 1999
  • Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH- induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization.  274:33072-33084. 1999
  • A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein.  274:31755-31758. 1999
  • Casein kinase II activity is required for transferrin receptor endocytosis.  274:30550-30556. 1999
  • The p38 mitogen-activated protein kinase is required for NF-κB- dependent gene expression. The role of TATA-binding protein (TBP).  274:30858-30863. 1999
  • The cytoplasmic domain of human FcγRIa alters the functional properties of the FcγRI·γ-chain receptor complex.  274:30328-30333. 1999
  • Regulation of cyclooxygenase-2 by interferon γ and transforming growth factor α in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases.  274:29138-29148. 1999
  • The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells.  274:29130-29137. 1999
  • Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913)).  274:28836. 1999
  • Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus Cna MSCRAMM. (vol 274, pg 24906, 1999).  274:28836-28836. 1999
  • The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization.  274:27553-27561. 1999
  • Ace is a collagen-binding MSCRAMM from Enterococcus faecalis.  274:26939-26945. 1999
  • Regulation of AMP deaminase by phosphoinositides.  274:25701-25707. 1999
  • Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM.  274:24906-24913. 1999
  • An analysis of the binding of repressor protein ModE to modABCD (molybdate transport) operator/promoter DNA of Escherichia coli.  274:24308-24315. 1999
  • The photoreactivity of the retinal age pigment lipofuscin.  274:23828-23832. 1999
  • Association of the epithelial sodium channel with Apx and α-spectrin in A6 renal epithelial cells.  274:23286-23295. 1999
  • Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption.  274:22739-22746. 1999
  • Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.  274:21276-21284. 1999
  • Interaction of syntaxins with the amiloride-sensitive epithelial sodium channel.  274:20812-80817. 1999
  • 15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase.  274:20083-20091. 1999
  • The inhibition of capacitative calcium entry due to ATP depletion but not due to glucosamine is reversed by staurosporine.  274:20165-20170. 1999
  • Analysis of tyro sine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22.  274:18769-18776. 1999
  • Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity.  274:18075-18080. 1999
  • Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation.  274:15487-15492. 1999
  • An IgA-binding peptide derived from a streptococcal surface protein.  274:14521-14524. 1999
  • An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro.  274:15194-15202. 1999
  • The structure of human lipoprotein A-I. Evidence for the 'belt' model.  274:14541-14544. 1999
  • Zinc content of Escherichia coli-expressed constitutive isoforms of nitric-oxide synthase. Enzymatic activity and effect of pterin.  274:14537-14540. 1999
  • Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells.  274:13915-13927. 1999
  • Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway.  274:13434-13442. 1999
  • The activation sequence of thrombospondin-1 interacts with the latency- associated peptide to regulate activation of latent transforming growth factor-β.  274:13586-13593. 1999
  • Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A2 (iPLA2) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA2 gene on chromosome 22q13.1.  274:9607-9616. 1999
  • Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages: 7,8-dihydro-8-oxoguanine and 5- hydroxycytosine.  274:8516-8523. 1999
  • The biochemical role of glutamine 188 in human galactose-1-phosphate uridyltransferase.  274:6559-6566. 1999
  • Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae.  274:5797-5809. 1999
  • Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion.  274:5692-5700. 1999
  • The Golgi apparatus plays a significant role in the maintenance of Ca2+ homeostasis in the vps33Δ vacuolar biogenesis mutant of saccharomyces cerevisiae.  274:5939-5947. 1999
  • Binding of xanthine oxidase to vascular endothelium: Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling.  274:4985-4994. 1999
  • Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal.  274:3602-3609. 1999
  • Regulation of the transglutaminase I gene. Identification of DNA elements involved in its transcriptional control in tracheobronchial epithelial cells.  274:3887-3896. 1999
  • Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae.  274:3189-3198. 1999
  • Human papillomavirus DNA replication: Interactions between the viral E1 protein and two subunits of human DNA polymerase α/primase.  274:2696-2705. 1999
  • Apolipoprotein-mediated plasma membrane microsolubilization: Role of lipid affinity and membrane penetration in the efflux of cellular cholesterol and phospholipid.  274:2021-2028. 1999
  • Apical sorting of bovine enteropeptidase does not involve detergent- resistant association with sphingolipid-cholesterol rafts.  274:1596-1605. 1999
  • Cloning of the murine beta5 integrin subunit promoter. Identification of a novel sequence mediating granulocyte-macrophage colony-stimulating factor-dependent repression of beta5 integrin gene transcription..  274:1366-1374. 1999
  • Identification of STRAP, a novel WD domain protein in transforming growth factor-β signaling.  273:34671-34674. 1998
  • The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.  273:34799-34805. 1998
  • Molecular cloning, characterization, and dynamics of rat formiminotransferase cyclodeaminase, a Golgi-associated 58-kDa protein.  273:33825-33834. 1998
  • Intragenic suppressors of mutant DNA topoisomerase I-induced lethality diminish enzyme binding of DNA.  273:31519-31527. 1998
  • Human Hsp70 and Hsp40 chaperone proteins facilitate human papillomavirus-11 E1 protein binding to the origin and stimulate cell-free DNA replication.  273:30704-30712. 1998
  • Multiple heparan sulfate chains are required for optimal syndecan-1 function.  273:29965-29971. 1998
  • The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61β and a cytosolic, deglycosylated intermediary.  273:29873-29878. 1998
  • Chronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells..  273:28721-28732. 1998
  • High affinity hormone binding to the extracellular N-terminal exodomain of the follicle-stimulating hormone receptor is critically modulated by exoloop 3.  273:28953-28958. 1998
  • An eukaryotic RuvB-like protein (RUVBL1) essential for growth.  273:27786-27793. 1998
  • Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system.  273:28378-28383. 1998
  • Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N6-ethenoadenine.  273:27245-27249. 1998
  • ORC5L, a new member of the human origin recognition complex, is deleted in uterine leiomyomas and malignant myeloid diseases.  273:27137-27145. 1998
  • Nitrosation of uric acid by peroxynitrite: Formation of a vasoactive nitric oxide donor.  273:24491-24497. 1998
  • Heparan sulfate proteoglycans as adhesive and anti-invasive molecules: Syndecans and glypican have distinct functions.  273:22825-22832. 1998
  • Structural requirements for major histocompatibility complex class II invariant chain endocytosis and lysosomal targeting.  273:20644-20652. 1998
  • cDNA cloning and characterization of a new human microsomal NAD+- dependent dehydrogenase that oxidizes all-trans-retinol and 3α- hydroxysteroids.  273:19778-19785. 1998
  • Regulation of casein kinase 2 by direct interaction with cell surface receptor CD5.  273:19183-19189. 1998
  • Lineage-specific signaling in melanocytes. c-Kit stimulation recruits p300/CBP to microphthalmia.  273:17983-17986. 1998
  • The human homolog of Saccharomyces cerevisiae CDC45.  273:18205-18209. 1998
  • Crystal structure and mutational analysis of the Escherichia coli putrescine receptor. Structural basis for substrate specificity.  273:17604-17609. 1998
  • Isoenzymes of pyruvate dehydrogenase phosphatase. DNA-derived amino acid sequences, expression, and regulation.  273:17680-17688. 1998
  • Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras.  273:14355-14362. 1998
  • Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C.  273:12135-12139. 1998
  • Major histocompatibility class II-mediated signal transduction is regulated by the protein-tyrosine phosphatase CD45.  273:11970-11979. 1998
  • Regulation of peroxisome proliferator-activated receptor α-induced transactivation by the nuclear orphan receptor TAK1/TR4.  273:10948-10957. 1998
  • Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5- bisphosphate coordinately regulate protein kinase C activity.  273:10624-10629. 1998
  • RhoB is stabilized by transforming growth factor β and antagonizes transcriptional activation.  273:9921-9926. 1998
  • Differential regulation of human neutrophil FcγRIIa (CD32) and FcγRIIIb (CD16)-induced Ca2+ transients.  273:8071-8079. 1998
  • Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I.  273:8425-8433. 1998
  • A role for superoxide in protein kinase C activation and induction of long-term potentiation.  273:4516-4522. 1998
  • Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling.  273:2344-2354. 1998
  • The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair.  273:1453-1461. 1998
  • Thrombospondin signaling of focal adhesion disassembly requires activation of phosphoinositide 3-kinase.  273:1755-1763. 1998
  • Molecular cloning, sequence analysis, expression, and tissue distribution of suppressin, a novel suppressor of cell cycle entry.  273:361-368. 1998
  • Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain.  272:31293-31300. 1997
  • Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells.  272:31427-31434. 1997
  • Identification of HsORC4, a member of the human origin of replication recognition complex.  272:28247-28251. 1997
  • Prion protein aggregation reverted by low temperature in transfected cells carrying a prion protein gene mutation.  272:28461-28470. 1997
  • The DNA cleavage reaction of DNA gyrase. Comparison of stable ternary complexes formed with enoxacin and CcdB protein..  272:27202-27209. 1997
  • Identification of an amiloride binding domain within the α-subunit of the epithelial Na+ channel.  272:21075-21083. 1997
  • Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex.  272:19746-19751. 1997
  • Interleukin-1 reduces the glycolytic utilization of glucose by pancreatic islets and reduces glucokinase mRNA content and protein synthesis by a nitric oxide-dependent mechanism.  272:17827-17835. 1997
  • Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin.  272:14769-14775. 1997
  • Epidermal growth factor induces CD44 gene expression through a novel regulatory element in mouse fibroblasts.  272:14139-14146. 1997
  • Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death.  272:12801-12808. 1997
  • Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast.  272:12091-12099. 1997
  • Pancreatic islets express a Ca2+-independent phospholipase A2 enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin.  272:11118-11127. 1997
  • Characterization of the response element and DNA binding properties of the nuclear orphan receptor germ cell nuclear factor/retinoid receptor- related testis-associated receptor.  272:10565-10572. 1997
  • The globin-based free radical of ferryl hemoglobin is detected in normal human blood.  272:7114-7121. 1997
  • cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3β,5α-hydroxysteroids.  272:7494-7500. 1997
  • A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A.  272:6561-6566. 1997
  • Hepatocyte growth factor alters the polarity of Madin-Darby canine kidney cell monolayers.  272:3471-3477. 1997
  • Expression of the cystic fibrosis phenotype in a renal amphibian epithelial cell line.  272:594-600. 1997
  • 'Oxidation inhibits substrate proteolysis by calpain I but not autolysis.  272:2005-2012. 1997
  • Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation.  271:30436-30441. 1996
  • Human immunodeficiency virus: Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complex.  271:33231-33235. 1996
  • Topoisomerase II-etoposide interactions direct the formation of drug- induced enzyme-DNA cleavage complexes.  271:29238-29244. 1996
  • Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation..  271:30222-30226. 1996
  • Kinetic interconversion of rat and bovine homologs of the α subunit of an amiloride-sensitive Na+ channel by C-terminal truncation of the bovine subunit.  271:26602-26608. 1996
  • Identification and cloning of centaurin-α. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain.  271:18859-18868. 1996
  • A 3' cis-acting element is involved in tumor necrosis factor-α gene expression in astrocytes.  271:22383-22390. 1996
  • Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human.  271:22376-22382. 1996
  • Functional reconstitution in situ of 5-hydroxytryptamine(2c) (5HT(2c)) receptors with α(q) and inverse agonism of 5HT(2c) receptor antagonists.  271:22591-22597. 1996
  • The luteinizing hormone/chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals.  271:19283-19287. 1996
  • Competition for a unique response element mediates retinoic acid inhibition of vitamin D3-stimulated transcription..  271:20650-20654. 1996
  • Regulation of epithelial sodium channels by short actin filaments.  271:17704-17710. 1996
  • Dissection of functional domains of the human DNA replication protein complex replication protein A.  271:17190-17198. 1996
  • A novel Ca2+-binding protein, p22, is required for constitutive membrane traffic.  271:10183-10187. 1996
  • Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli.  271:9519-9525. 1996
  • Dissociation of cyclic inositol phosphohydrolase activity from annexin III.  271:8295-8299. 1996
  • Exoloop 3 of the luteinizing hormone/choriogonadotropin receptor: Lys583 is essential and irreplaceable for human choriogonadotropin (hCG)-dependent receptor activation but not for high affinity hCG binding.  271:7301-7304. 1996
  • Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells.  271:6963-6971. 1996
  • G-protein regulation of outwardly rectified epithelial chloride channels incorporated into planar bilayer membranes.  271:4776-4780. 1996
  • Regulation of epithelial sodium channels by the cystic fibrosis transmembrane conductance regulator.  271:4725-4732. 1996
  • Cyclic AMP and chloride-dependent regulation of the apical constitutive secretory pathway in colonic epithelial cells.  271:4381-4387. 1996
  • Cloning and regulation of cornifin β, a new member of the cornifin/spr family: Suppression by retinoic acid receptor-selective retinoids.  271:3737-3742. 1996
  • The role of cytosolic calcium in chronic adaptation to phosphate depletion in opossum kidney cells.  271:3902-3906. 1996
  • Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism*.  271:1029-1042. 1996
  • Triple-barrel organization of ENaC, a cloned epithelial Na+ channel.  271:807-816. 1996
  • Erratum: Cloning of an epithelial chloride channel from bovine trachea (Journal of Biological Chemistry (1995) 270 (31016-31026)).  271:7244. 1996
  • Erratum: Diversity of the pyruvate dehydrogenase kinase gene family in humans (Journal of Biological Chemistry (1995) 270 (28989-28994)).  271:1250. 1996
  • Erratum: The luteinizing hormone-chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals (Journal of Biological Chemistry (1996) 271 (19283-19287)).  271:26444. 1996
  • Human immunodeficiency virus type-1 reverse transcriptase: Contribution of MET-184 to binding of nucleoside 5′-triphosphate.  271:13656-13662. 1996
  • Metabolism of serotonin to n-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.  271:12281-12286. 1996
  • Cloning of an epithelial chloride channel from bovine trachea.  270:31016-31026. 1995
  • Roles of amino acid residues surrounding phosphorylation site 1 of branched-chain α-ketoacid dehydrogenase (BCKDH) in catalysis and phosphorylation site recognition by BCKDH kinase.  270:31071-31076. 1995
  • The effects of brefeldin A on the glucose transport system in rat adipocytes: Implications regarding the intracellular locus of insulin-sensitive Glut4.  270:30199-30204. 1995
  • The human gp39 promoter: Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation.  270:29624-29627. 1995
  • Interaction between cystic fibrosis transmembrane conductance regulator and outwardly rectified chloride channels.  270:29194-29200. 1995
  • Erratum: Crystal structure of a complement factor D mutant expressing enhanced catalytic activity (Journal of Biological Chemistry (1995) 270 (24399-24405)).  270:31414. 1995
  • Insulin-induced egr-1 expression in Chinese hamster ovary cells is insulin receptor and insulin receptor substrate-1 phosphorylation-independent. Evidence of an alternative signal transduction pathway..  270:26632-26638. 1995
  • Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels.  270:26086-26091. 1995
  • The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain.  270:13814-13818. 1995
  • Heparan sulfate-mediated cell aggregation: Syndecans-1 and -4 mediate intercellular adhesion following their transfection into human B lymphoid cells.  270:5077-5083. 1995
  • Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase: Active-site amino acid sequence explains substrate specificity compared with liver isozymes.  270:3625-3630. 1995
  • A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.  270:6141-6148. 1995
  • Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species.  270:18825-18830. 1995
  • Calculation of absolute metabolic flux and the elucidation of the pathways of glutamate labeling in perfused rat heart by 13C NMR spectroscopy and nonlinear least squares analysis.  270:7999-8008. 1995
  • Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase.  270:17437-17441. 1995
  • Crystal structure of a complement factor D mutant expressing enhanced catalytic activity.  270:24399-24405. 1995
  • Diversity of the pyruvate dehydrogenase kinase gene family in humans.  270:28989-28994. 1995
  • Effect of the arrangement of tandem repeating units of class A amphipathic α-helixes on lipid interaction.  270:1602-1611. 1995
  • Effect of the cholesterol content of reconstituted LpA-I on lecithin:cholesterol acyltransferase activity.  270:5151-5157. 1995
  • Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids.  270:6022-6029. 1995
  • High hydrostatic pressure induces the dissociation of cpn60 tetradecamers and reveals a plasticity of the monomers.  270:2061-2066. 1995
  • Identification and characterization of a novel squamous cell-associated gene related to PMP22.  270:28910-28916. 1995
  • Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized.  270:18543-18550. 1995
  • Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor.  270:14776-14785. 1995
  • Regulation of transforming growth factor-β activation by discrete sequences of thrombospondin 1.  270:7304-7310. 1995
  • Signal transduction by a CD16/CD7/Jak2 fusion protein.  270:18420-18427. 1995
  • Specific Alu binding protein from human sperm chromatin prevents DNA methylation.  270:18539-18542. 1995
  • The Ca2+ dependence of human Fcγ receptor-initiated phagocytosis.  270:22301-22307. 1995
  • The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide.  270:17641-17644. 1995
  • The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication.  270:27283-27291. 1995
  • Truncated forms of the human prion protein in normal brain and in prion diseases.  270:19173-19180. 1995
  • Ganglioside G(D1α) in cerebellar Purkinje cells: Its specific absence in mouse mutants with Purkinje cell abnormality and altered immunoreactivity in response tc conjunctive stimuli causing long term desensitization.  269:32418-32425. 1994
  • Molecular cloning of the p45 subunit of pyruvate dehydrogenase kinase.  269:29720-29724. 1994
  • Autonomously active protein kinase C in the maintenance phase of N- methyl-D-aspartate receptor-independent long term potentiation.  269:27958-27963. 1994
  • Phosphorylation and activation of a bovine tracheal anion channel by Ca2+/calmodulin-dependent protein kinase II.  269:26642-26649. 1994
  • Hemolytically inactive C4B complement allotype caused by a proline to leucine mutation in the C5-binding site.  269:27727-27731. 1994
  • The glycosylation of phosphoglucomutase is modulated by carbon source and heat shock in Saccharomyces cerevisiae.  269:27143-27148. 1994
  • The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-β.  269:26783-26788. 1994
  • Thrombospondin binds and activates the small and large forms of latent transforming growth factor-β in a chemically defined system.  269:26775-26782. 1994
  • Binding of apolipoprotein A-I model peptides to lipid bilayers. Measurement of binding isotherms and peptide-lipid headgroup interactions.  269:23904-23910. 1994
  • Cell-free replication of the human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts.  269:24058-24065. 1994
  • The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein.  269:22975-22982. 1994
  • Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids.  269:21440-21447. 1994
  • Expression of syndecan-1 inhibits cell invasion into type I collagen.  269:20013-20019. 1994
  • Site-directed mutagenesis of phosphorylation sites of the branched chain α-ketoacid dehydrogenase complex.  269:18583-18587. 1994
  • G-proteins modulate amiloride-sensitive sodium channels.  269:17780-17783. 1994
  • Nucleotide-specific transcriptional pausing in the pyrBI leader region of Escherichia coli K-12..  269:18185-18191. 1994
  • Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family.  269:17802-17808. 1994
  • Characterization of the mitochondrial binding and import properties of purified yeast F1-ATPase β subunit precursor. Import requires external ATP.  269:7192-7200. 1994
  • Mechanism and subcellular localization of secretory IgM polymer assembly.  269:17338-17348. 1994
  • Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45.  269:17238-17244. 1994
  • Cytokines and HIV envelope glycoprotein gp120 stimulate Na+/H+ exchange in astrocytes.  269:13811-13816. 1994
  • Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior.  269:13100-13106. 1994
  • Molecular characterization of protein Sir, a streptococcal cell surface protein that binds both immunoglobulin A and immunoglobulin G.  269:13458-13464. 1994
  • A peptide encoding the c-Jun δ domain inhibits the activity of a c-Jun amino-terminal protein kinase.  269:11186-11191. 1994
  • Matrix effects suggest an important influence of DNA-polyacrylamide interactions on the electrophoretic mobility of DNA.  269:10156-10162. 1994
  • Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon γ: Antagonism by retinoic acid and transforming growth factor β1.  269:2016-2022. 1994
  • Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N- acyltransferase.  269:19375-19379. 1994
  • Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis.  269:7185-7191. 1994
  • Molecular determinants of bioactivity of the Saccharomyces cerevisiae lipopeptide mating pheromone.  269:19817-19825. 1994
  • Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives.  269:26066-26075. 1994
  • Repression of transforming growth factor β1 promoter by the adenovirus oncogene E1A. Identification of a unique GC-rich sequence as a target for E1A repression.  269:25392-25399. 1994
  • Structure and expression of the human gene for the α subunit of prolyl 4- hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues.  269:27847-27854. 1994
  • Xylosyl transfer to an endogenous renal acceptor. Characteristics of the reaction and properties of the product.  269:11503-11508. 1994
  • Xylosyl transfer to an endogenous renal acceptor. Purification of the transferase and the acceptor and their identification as glycogenin.  269:11509-11513. 1994
  • Use of transgenic mice to study regulation of gene expression in the parietal cell lineage of gastric units.  268:26559-26570. 1993
  • A mitochondrial porin cDNA predicts the existence of multiple human porins.  268:12143-12149. 1993
  • Arachidonic acid release from aortic smooth muscle cells induced by [Arg8]vasopressin is largely mediated by calcium-independent phospholipase A2.  268:20713-20716. 1993
  • Brefeldin a causes a defect in secretion in Saccharomyces cerevisiae.  268:3040-3043. 1993
  • Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity.  268:11176-11187. 1993
  • Characterization of the DNA-melting function of the Rickettsia prowazekii RNA polymerase.  268:3897-3902. 1993
  • Control of protein traffic between distinct plasma membrane domains. Requirement for a novel 108,000 protein in the fusion of transcytotic vesicles with the apical plasma membrane.  268:1876-1885. 1993
  • Cytosolic domain of the human immunodeficiency virus envelope glycoproteins binds to calmodulin and inhibits calmodulin-regulated proteins.  268:22895-22899. 1993
  • Heparin-binding peptides from thrombospondins 1 and 2 contain focal adhesion-labilizing activity.  268:26784-26789. 1993
  • Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors.  268:19312-19320. 1993
  • Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants.  268:22322-22330. 1993
  • Phosphoglucomutase in Saccharomyces cerevisiae is a cytoplasmic glycoprotein and the acceptor for a Glc-phosphotransferase.  268:8341-8349. 1993
  • Primary structure of pyruvate dehydrogenase kinase establishes a new family of eukaryotic protein kinases.  268:26602-26606. 1993
  • Reciprocal effects of apolipoprotein and lytic peptide analogs on membranes. Cross-sectional molecular shapes of amphipathic α helixes control membrane stability.  268:22112-22118. 1993
  • YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis.  268:21686-21692. 1993
  • Erratum: Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes (The Journal of Biological Chemistry (1992) 267 (18498-18504)).  267:26200. 1992
  • Functional reconstitution of a chloride channel protein from bovine trachea.  267:20630-20637. 1992
  • Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes.  267:18498-18504. 1992
  • INVITRO ISOPRENYLATION AND MEMBRANE ASSOCIATION OF MOUSE ROD PHOTORECEPTOR CGMP PHOSPHODIESTERASE ALPHA-SUBUNIT AND BETA-SUBUNIT EXPRESSED IN BACTERIA.  267:8458-8463. 1992
  • Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.  267:6257-6262. 1992
  • Branched-chain α-ketoacid dehydrogenase kinase. Molecular cloning, expression, and sequence similarity with histidine protein kinases.  267:13127-13130. 1992
  • CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution.  267:19724-19729. 1992
  • Crystal structure of recombinant human interleukin-4.  267:20371-20376. 1992
  • Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells.  267:18002-18007. 1992
  • Erratum: Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production (Journal of Biological Chemistry (1992) 267 (13656-13660)).  267:19752. 1992
  • Evidence for GTP-binding protein involvement in the tyrosine phosphorylation of the T cell receptor ζ chain.  267:14527-14530. 1992
  • In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase α and β subunits expressed in bacteria.  267:8458-8463. 1992
  • Inhibition of protein phosphatases blocks myogenesis by first altering MyoD binding activity.  267:15140-15145. 1992
  • Intermolecular triplex formation distorts the DNA duplex in the regulatory region of human papillomavirus type-11.  267:5488-5494. 1992
  • Membrane interactions of synthetic peptides corresponding to amphipathic helical segments of the human immunodeficiency virus type-1 envelope glycoprotein.  267:7121-7127. 1992
  • Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production.  267:13656-13660. 1992
  • Photoaffinity labeling and characterization of isolated inositol 1,3,4,5- tetrakisphosphate- and inositol hexakisphosphate-binding proteins.  267:9071-9079. 1992
  • Purification and characterization of heterodimeric human immunodeficiency virus type 1 (HIV-1) reverse transcriptase produced by in vitro processing of p66 with recombinant HIV-1 protease.  267:14227-14232. 1992
  • Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene product.  267:6455-6458. 1992
  • Role of protein kinase C in insulin's regulation of c-fos transcription.  267:9223-9228. 1992
  • Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein.  267:6789-6795. 1992
  • Multiple interacting sites regulate astrocyte-specific transcription of the human gene for glial fibrillary acidic protein.  266:18877-18883. 1991
  • Inhibition and stimulation of c-myc gene transcription by insulin in rat hepatoma cells: Insulin alters the intragenic pausing of c-myc transcription.  266:17995-18001. 1991
  • Interferon-γ-induced astrocyte class II major histocompatibility complex gene expression is associated with both protein kinase C activation and Na+ entry.  266:18119-18126. 1991
  • Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells.  266:16485-16490. 1991
  • Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts.  266:16376-16379. 1991
  • Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor.  266:5670-5675. 1991
  • Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells.  266:11262-11269. 1991
  • Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver.  266:10227-10233. 1991
  • Topoisomerase mutants and physiological conditions control supercoiling and Z-DNA formation in vivo.  266:2576-2581. 1991
  • Erratum: Sequence analysis, biogenesis, and mitochondrial import of the α-subunit of rat liver propionyl-CoA carboxylase (The Journal of Biological Chemistry, Vol. 264 (1989) 12680-12685).  266:4660. 1991
  • Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases α, β, and γ by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine, and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs.  266:1754-1762. 1991
  • Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain gene.  266:221-228. 1991
  • Mouse opsin. Gene structure and molecular basis of multiple transcripts.  265:20563-20569. 1990
  • Thermodynamics of the binding of human apolipoprotein A-I to dimyristoylphosphatidylglycerol.  265:20829-20832. 1990
  • Nuclear magnetic resonance and molecular modeling studies on O-β-D-galactopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→0)-L-serine, a carbohydrate-protein linkage region fragment from connective tissue proteoglycans.  265:18256-18262. 1990
  • Characterization of transcriptional initiation from promoters P1 and P2 of the pyrBI operon of Escherichia coli K12..  265:19091-19099. 1990
  • Structure of the human laminin B1 chain gene.  265:15611-15616. 1990
  • Bone acidic glycoprotein-75 is a major synthetic product of osteoblastic cells and localized as 75- and/or 50-kDa forms in mineralized phases of bone and growth plate and in serum..  265:14956-14963. 1990
  • Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 Å resolution.  265:14016-14022. 1990
  • Compartmentalization of mammalian proteins produced in Escherichia coli.  265:13066-13073. 1990
  • Nuclear magnetic resonance investigation of the interaction with phospholipid of an amphipathic α-helix-forming peptide of the apolipoprotein class.  265:12217-12223. 1990
  • Insulin's regulation of c-fos gene transcription in hepatoma cells.  265:11700-11705. 1990
  • Regulation of transglutaminase Type II by transforming growth factor-β1 in normal and transformed human epidermal keratinocytes.  265:11098-11104. 1990
  • Structure of the human type IV collagenase gene.  265:11077-11082. 1990
  • An anti-sense c-erbA clone inhibits thyroid hormone-induced expression from the α-myosin heavy chain promoter.  265:6489-6493. 1990
  • Identification and sequence analysis of four complement factor H-related transcripts in mouse liver.  265:3193-3201. 1990
  • Isolation, purification, and partial characterization of suppressin, a novel inhibitor of cell proliferation.  265:158-165. 1990
  • An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol.  264:20540-20546. 1989
  • 7-Azidoactinomycin D: A novel probe for examining actinomycin D-DNA interactions.  264:7262-7266. 1989
  • Biochemical characterization of the η chain of the T-cell receptor. A unique subunit related to ξ.  264:14812-14817. 1989
  • Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membrane.  264:2195-2198. 1989
  • Inhibition of the high affinity Fc receptor (Fc(γ)RI) on human monocytes by porphyrin photosensitization is highly specific and mediated by the generation of superoxide radicals.  264:11407-11413. 1989
  • Phorbol ester or epidermal growth factor (EGF) stimulates the concurrent accumulation of mRNA for the EGF receptor and its ligand transforming growth factor-α in a breast cancer cell line.  264:4021-4027. 1989
  • Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide charges.  264:4628-4635. 1989
  • Sequence analysis, biogenesis, and mitochondrial import of the α-subunit of rat liver propionyl-CoA carboxylase.  264:12680-12685. 1989
  • Substitutions engineered by chemical synthesis at three conserved sites in mitochondrial cytochrome c. Thermodynamic and functional consequences.  264:15199-15209. 1989
  • Supercoiling and integration host factor change the DNA conformation and alter the flow of convergent transcription in phage Mu..  264:3035-3042. 1989
  • Synthetic amphipathic peptides resembling apolipoproteins stimulate the release of human placental lactogen.  264:9215-9219. 1989
  • Synthetic transit peptides inhibit import and processing of mitochondrial precursor proteins.  264:9552-9558. 1989
  • Transforming growth factor-α in the mammalian brain. Immunohistochemical detection in neurons and characterization of its mRNA.  264:3880-3883. 1989
  • Chinese hamster ovary cell mutants deficient in an anion exchanger functionally similar to the erythroid band 3.  263:18607-18613. 1988
  • A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles.  263:13823-13830. 1988
  • Altered metabolism of thrombospondin by Chinese hamster ovary cells defective in glycosaminoglycan synthesis.  263:6400-6406. 1988
  • Characterization of the human gene for a polypeptide that acts both as the β subunit of prolyl 4-hydroxylase and as protein disulfide isomerase.  263:16218-16224. 1988
  • Chemical modification of bovine prothrombin fragment 1 in the presence of Tb3+ ions. Sequence studies on 3-γ-MGlu-fragment 1.  263:8150-8156. 1988
  • Identification of a promoter region in the CGβ gene cluster.  263:7322-7329. 1988
  • Import of the malate dehydrogenase precursor by mitochondria. Cleavage within leader peptide by matrix protease leads to formation of intermediate-sized form.  263:12085-12091. 1988
  • Interactions of chloride and amiloride with the renal Na+/H+ antiporter.  263:7216-7221. 1988
  • Localization of the glucose phosphotransferase to a cytoplasmically accessible site on intracellular membranes..  263:17792-17797. 1988
  • Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c.  263:8625-8634. 1988
  • Phospholipid bindng properties of bovine prothrombin peptide residues 1-45.  263:14216-14223. 1988
  • Preservation of intermediary metabolism in saponin-permeabilized rat adipocytes.  263:10667-10673. 1988
  • Structure of the murine complement factor H gene.  263:16720-16724. 1988
  • Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type β transforming growth factor.  263:13916-13921. 1988
  • Uridine phosphorylase from Schistosoma mansoni.  263:6081-6086. 1988
  • Increase in cholesterol sulfotransferase activity during in vitro squamous differentiation of rabbit tracheal epithelial cells and its inhibition by retinoic acid.  262:13069-13074. 1987
  • Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I..  262:12189-12195. 1987
  • Nucleotide sequence and characterization of the pyrF operon of Escherichia coli K12..  262:10239-10245. 1987
  • Studies of synthetic peptide analogs of the amphipathic helix. Effect of charge distribution, hydrophobicity, and secondary structure on lipid association and lecithin:cholesterol acyltransferase activation..  262:9389-9396. 1987
  • Crystallization and preliminary X-ray investigation of uridine phosphorylase from Escherichia coli..  262:2852-2853. 1987
  • Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone..  262:2900-2907. 1987
  • Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.  262:189-197. 1987
  • Glucose-1-phosphotransferase and N-acetylglucosamine-1-phosphotransferase have distinct acceptor specificities.  262:4377-4381. 1987
  • Isoproterenol-mediated parotid gland hypertrophy is inhibited by effectors of 4β-galactosyltransferase.  262:11706-11713. 1987
  • Shunting of insulin from a retroendocytotic pathway to a degradative pathway by sodium vanadate.  262:12005-12012. 1987
  • Accumulation of cholesterol 3-sulfate during in vitro squamous differentiation of rabbit tracheal epithelial cells and its regulation by retinoids.  261:13898-13904. 1986
  • Characterization of a regulatory region of the steroid 21-hydroxylase gene.  261:15353. 1986
  • Characterization of transglutaminase activity in rabbit tracheal epithelial cells. Regulation by retinoids.  261:15097-15101. 1986
  • Positive and negative regulation of the Mu operator by Mu repressor and Escherichia coli integration host factor.  261:3744-3752. 1986
  • Sulfate transport-deficient mutants of Chinese hamster ovary cells. Sulfation of glycosaminoglycans dependent on cysteine.  261:15725-15733. 1986
  • Surface receptor-mediated activation of adenylate cyclase in dictyostelium. Regulation by guanine nucleotides in wild-type cells and aggregation deficient mutants.  261:15121-15125. 1986
  • Cleavage of bovine skin type III collagen by proteolytic enzymes. Relative resistance of the fibrillar form.  260:16411-16417. 1985
  • Effects of insulin alone on the accumulation of a specific mRNA in rat hepatoma cells.  260:16418-16423. 1985
  • Intrahepatic assembly of very low density lipoproteins. Varied synthetic response of individual apolipoproteins to fasting.  260:14137-14144. 1985
  • Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism.  260:9057-9067. 1985
  • Studies of synthetic peptide analogs of the amphiphatic helix. Correlation of structure with function.  260:10256-10262. 1985
  • Studies of synthetic peptide analogs of the amphiphatic helix. Structure of complexes with dimyristoyl phosphatidylcholine.  260:10248-10255. 1985
  • Characterization of distinct tyrosine-specific protein kinases in B and T lymphocytes.  260:4351-4356. 1985
  • Identification of a trpG-related glutamine amide transfer domain in Escherichia coli GMP synthetase.  260:3350-3354. 1985
  • Biochemical characterization of mucous glycoproteins synthesized and secreted by hamster tracheal epithelial cells in primary culture.  260:4021-4027. 1985
  • Identification and cyclic AMP-induced modification of the cyclic AMP receptor in Dictyostelium discoideum.  260:1757-1764. 1985
  • The role of enzyme sequestration in the regulation of the adenylate cyclase of Dictyostelium discoideum.  260:3613-3616. 1985
  • Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum.  259:12318-12321. 1984
  • Transfer of cholesterol from its site of synthesis to the plasma membrane.  259:14624-14630. 1984
  • The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct.  259:8202-8209. 1984
  • Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action.  259:6376-6384. 1984
  • The use of monoclonal antibodies to fragments of chicken type IV collagen in structural and localization studies.  258:5794-5797. 1983
  • Studies of synthetic peptide analogs of the amphipathic helix. Competitive displacement of exchangeable apolipoproteins from native lipoproteins.  258:2290-2295. 1983
  • Asymmetrical distributions of the Na+/H+ antiporter in the renal proximal tubule epithelial cell.  258:13513-13516. 1983
  • Isolation and characterization of human erythrocyte insulin receptors.  258:5021-5026. 1983
  • Mixed type inhibition of the renal Na+/H+ antiporter by the Li+ and amiloride. Evidence for a modifier site.  258:9710-9716. 1983
  • Intrahepatic assembly of very low density lipoproteins. Effect of fatty acids on triacylglycerol and apolipoprotein synthesis.  257:10908-10913. 1982
  • Partial characterization of insulin receptors from rat myocytes.  257:11128-11134. 1982
  • Purification and Macromolecular Properties of a Sialic-Acid Specific Lectin from Limax Flavus.  257:7574-7580. 1982
  • A unique "mini" pepsinogen isolated from bullfrog esophageal glands..  257:795-798. 1982
  • Structural domains of vesicular stomatitis virus. A study by differential scanning calorimetry, thermal gel analysis, and thermal electron microscopy..  257:12-15. 1982
  • Does simian virus 40 T antigen unwind DNA?.  256:10156-10160. 1981
  • Regional synthesis of monohydroxy eicosanoids by the kidney.  256:10221-10223. 1981
  • Proton gradients in renal cortex brush-border membrane vesicles. Demonstration of a rheogenic proton flux with acridine orange..  256:11663-11666. 1981
  • Enhanced chick oviduct dolichol kinase activity during estrogen-induced differentiation.  256:632-635. 1981
  • Alignment of the peptides derived from acid-catalyzed cleavage of an aspartylprolyl bond in the major internal structural polypeptide of avian retroviruses.  255:6962-6965. 1980
  • Structural and functional properties of cytochrome c oxidases isolated from sharks..  255:2722-2728. 1980
  • Pseudouridylation of tRNAs and its role in regulation in Salmonella typhimurium..  254:5111-5119. 1979
  • Enzymatic phosphorylation of dolichol in central nervous tissue.  254:7129-7136. 1979
  • Interaction of the chiral pyruvate analog, 2-keto-3-bromobutyrate, with pyruvate lyases. 2-Keto-3-deoxygluconate-6-phosphate aldolase of Pseudomonas putida.  254:5862-5865. 1979
  • Triacylglycerol synthesis in isolated fat cells. Evidence that the sn glycerol 3 phosphate and dihydroxyacetone phosphate acyltransferase activities are dual catalytic functions of a single microsomal enzyme.  251:5738-5744. 1976
  • Characterization of gastric mucosal membranes. VIII. The localization of peptides by iodination and phosphorylation.  250:4802-4809. 1975
  • Enzymatic reduction of nicotinamide adenine dinucleotide phosphate induced by radiolysis.  250:716-719. 1975
  • Effects of colicin K on a mutant of Escherichia coli deficient in Ca2+,Mg2+ activated adenosine triphosphatase.  249:6138-6143. 1974
  • Isolation and characterization of the immune macroglobulin from the paddlefish, Polyodon spathula..  246:6760-6769. 1971
  • Physical and chemical characterization of an oyster hemagglutinin..  244:4128-4135. 1969
  • Mucopolysaccharide sulfation in chick embryo cartilage. II. Characterization of the endogenous acceptor..  242:4956-4962. 1967
  • Mucopolysaccharide sulfation in chick embryo cartilage. I. Properties of the sulfation system..  242:1685-1689. 1967
  • Studies on antigen conformation during antibody purification..  238:1362-1366. 1963
  • International Standard Serial Number (issn)

  • 0021-9258
  • Electronic International Standard Serial Number (eissn)

  • 1083-351X