Cancer Cell

Comparative Molecular Life History of Spontaneous Canine and Human Gliomas..  37:243-257.e7. 2020

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.  36:51-67.e7. 2019

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.  35:204-220.e9. 2019

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.  34:211-224.e6. 2018

Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors.  34:119-135.e10. 2018

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.  33:1004-1016.e5. 2018

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.  33:690-705.e9. 2018

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.  33:721-735.e8. 2018

Genomic and Functional Approaches to Understanding Cancer Aneuploidy.  33:676-689.e3. 2018

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.  33:706-720.e9. 2018

Erratum: Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer (Cancer Cell (2017) 31(4) (532–548.e7)(S1535610817300600)(10.1016/j.ccell.2017.02.017)).  31:844-847. 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.  31:737-754.e6. 2017

Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.  31:532-548.e7. 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.  30:891-908. 2016

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.  30:92-107. 2016

Erratum to Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival [Cancer Cell 25, 719-734; (2014)].  28:831-833. 2015

Treatment of Chronic Myelogenous Leukemia by Blocking Cytokine Alterations Found in Normal Stem and Progenitor Cells.  27:671-681. 2015

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival.  25:719-734. 2014

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia.  25:257. 2014

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia.  24:575-588. 2013

The Role of Cdk5 in Neuroendocrine Thyroid Cancer.  24:499-511. 2013

Erratum to The E3Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity [Cancer Cell 23, (2013) 332-346].  23:853. 2013

Erratum to Mechanistic rationale for inhibition of poly(ADP-Ribose) polymerase in ETS gene fusion-positive prostate cancer [Cancer Cell, 19 (2011) 664-678].  23:557. 2013

Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.  23:302-315. 2013

The E3 ubiquitin ligase siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity.  23:332-346. 2013

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression.  22:180-193. 2012

LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma.  21:751-764. 2012

Altered Microenvironmental Regulation of Leukemic and Normal Stem Cells in Chronic Myelogenous Leukemia.  21:577-592. 2012

Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib.  21:266-281. 2012

An Animal Model of MYC-Driven Medulloblastoma.  21:155-167. 2012

Aurora Kinase-A Inactivates DNA Damage-Induced Apoptosis and Spindle Assembly Checkpoint Response Functions of p73.  21:196-211. 2012

JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation.  19:283-294. 2011

Altered Hematopoietic Cell Gene Expression Precedes Development of Therapy-Related Myelodysplasia/Acute Myeloid Leukemia and Identifies Patients at Risk.  20:591-605. 2011

Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer.  20:187-199. 2011

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer.  19:664-678. 2011

Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3.  19:498-511. 2011

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation.  20:11-24. 2011

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression.  17:443-454. 2010

Effective Targeting of Quiescent Chronic Myelogenous Leukemia Stem Cells by Histone Deacetylase Inhibitors in Combination with Imatinib Mesylate.  17:427-442. 2010

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1.  17:98-110. 2010

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress.  17:41-52. 2010

Somatic Single Hits Inactivate the X-Linked Tumor Suppressor FOXP3 in the Prostate.  16:336-346. 2009

Tumor Suppression by Phospholipase C-β3 via SHP-1-Mediated Dephosphorylation of Stat5.  16:161-171. 2009

Proteasomal and Genetic Inactivation of the NF1 Tumor Suppressor in Gliomagenesis.  16:44-54. 2009

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells.  15:501-513. 2009

The Role of SPINK1 in ETS Rearrangement-Negative Prostate Cancers.  13:519-528. 2008

Integrative Genomics Analysis Reveals Silencing of β-Adrenergic Signaling by Polycomb in Prostate Cancer.  12:419-431. 2007

Rewired ERK-JNK Signaling Pathways in Melanoma.  11:447-460. 2007

Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression.  8:393-406. 2005

Lost in translation: Dysregulation of cap-dependent translation and cancer.  5:519-523. 2004

Cancer therapeutics in yeast.  2:267-273. 2002