Neurobiology of Aging

Structural complexity is negatively associated with brain activity: a novel multimodal test of compensation theories of aging.  98:185-196. 2021

Innovative approaches in cognitive aging.  83:150-154. 2019

Cyclic O3 exposure synergizes with aging leading to memory impairment in male APOE ε3, but not APOE ε4, targeted replacement mice.  81:9-21. 2019

Dendritic spine remodeling accompanies Alzheimer's disease pathology and genetic susceptibility in cognitively normal aging.  73:92-103. 2019

Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss.  59:41-54. 2017

Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease.  49:216.e7. 2017

Discrepancies between fluid and crystallized ability in healthy adults: a behavioral marker of preclinical Alzheimer's disease.  46:68-75. 2016

Assessment of the genetic variance of late-onset Alzheimer's disease.  41:200.e13-200.e20. 2016

The loss of glucose-regulated protein 78 (GRP78) during normal aging or from siRNA knockdown augments human alpha-synuclein (α-syn) toxicity to rat nigral neurons.  36:2213-2223. 2015

Commentary: Is Alzheimer's disease uniquely human?.  36:553-555. 2015

Erratum to "Exploratory analysis of seven Alzheimer's disease genes: Disease progression" [Neurobiol. Aging 34, (2013), 1310.e1-1310.e7], doi:10.1016/j.neurobiolaging.2012.08.014.  35:2661. 2014

Seizure resistance without parkinsonism in aged mice after tau reduction.  35:2617-2624. 2014

Protective effect of LRRK2 p.R1398H on risk of Parkinson's disease is independent of MAPT and SNCA variants..  35:266.e5-266.14. 2014

Effect of high-fat diet on metabolic indices, cognition, and neuronal physiology in aging F344 rats.  34:1977-1987. 2013

Exploratory analysis of seven Alzheimer's disease genes: Disease progression.  34:1310.e1-1310.e7. 2013

Impact of changed positive and negative task-related brain activity on word-retrieval in aging.  33:656-669. 2012

Age-related changes in Arc transcription and DNA methylation within the hippocampus.  32:2198-2210. 2011

Age-related brain pathology in Octodon degu: Blood vessel, white matter and Alzheimer-like pathology.  32:1651-1661. 2011

Knockout of plasminogen activator inhibitor 1 gene reduces amyloid beta peptide burden in a mouse model of Alzheimer's disease.  32:1079-1089. 2011

The val¹⁵⁸met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease.  31:1064-1068. 2010

DNA methylation impacts on learning and memory in aging.  30:549-560. 2009

Somatic mitochondrial DNA mutations in single neurons and glia.  26:1343-1355. 2005

Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice.  26:929-937. 2005

Changes in the expression of the NR2B subunit during aging in macaque monkeys.  25:201-208. 2004

Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons.  21:797-806. 2000

Age-related decline in water maze learning and memory in rats: Strain differences.  21:671-681. 2000

Exotic mice as models for aging research: Polemic and prospectus.  20:217-231. 1999

Exotic mice for aging: Authors' reply.  20:245-246. 1999

Elevated adenosine monophosphate deaminase activity in Alzheimer's disease brain.  19:385-391. 1998

Aging and caloric restriction: Human effects and mode of action.  16:851-852. 1995

Beta amyloid is neurotoxic in hippocampal slice cultures.  16:779-789. 1995

Authors' response to commentaries.  10:446-448. 1989

Familial Alzheimer's disease: Progress and problems.  10:417-425. 1989

Stability of dendrites in cortical barrels of C57BL/6N mice between 4 and 45 months.  7:101-105. 1986

Stability of synaptic density and spine volume in dentate gyrus of aged rats.  4:77-87. 1983

Enhancement of maze learning in old C57BL/6 mice by dietary lecithin.  3:223-226. 1982