Cell

In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.  184:1865-1883.e20. 2021

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise.  181:1464-1474. 2020

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders.  179:1469-1482.e11. 2019

Effector TH17 Cells Give Rise to Long-Lived TRM Cells that Are Essential for an Immediate Response against Bacterial Infection.  178:1176-1188.e15. 2019

Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions.  177:478-491.e20. 2019

Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2.  176:1310-1324.e10. 2019

Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.  176:113-126.e15. 2019

Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060)).  174:1034-1035. 2018

Erratum: Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer (Cell (2017) 171(3) (540–556.e25) (S0092867417310565) (10.1016/j.cell.2017.09.007)).  174:1033. 2018

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.  173:1705-1715.e16. 2018

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.  173:386-399.e12. 2018

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.  173:400-416.e11. 2018

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.  173:291-304.e6. 2018

Comprehensive Characterization of Cancer Driver Genes and Mutations.  173:371-385.e18. 2018

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.  173:338-354.e15. 2018

Oncogenic Signaling Pathways in The Cancer Genome Atlas.  173:321-337.e10. 2018

Pathogenic Germline Variants in 10,389 Adult Cancers.  173:355-370.e14. 2018

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.  173:305-320.e10. 2018

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer.  171:540-556.e25. 2017

Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.  170:249-259.e25. 2017

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.  169:1327-1341.e23. 2017

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.  169:6-12. 2017

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.  168:830-842.e7. 2017

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.  167:843-857.e14. 2016

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.  167:397-404.e9. 2016

A pro-metastatic tRNA pathway.  165:1314-1315. 2016

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.  164:550-563. 2016

Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins.  164:45-56. 2016

Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype.  163:1204-1213. 2015

Daughter's Tolerance of Mom Matters in Mate Choice.  162:467-469. 2015

Identification of Genetic Factors that Modify Clinical Onset of Huntington's Disease.  162:516-526. 2015

Neuronal activity promotes glioma growth through neuroligin-3 secretion.  161:803-816. 2015

Snap Shot: Sensing and signaling by cilia.  161:692-692.e1. 2015

Integrated Genomic Characterization of Papillary Thyroid Carcinoma.  159:676-690. 2014

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.  158:929-944. 2014

Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477)).  157:753. 2014

Merkel cells transduce and encode tactile stimuli to drive aβ-Afferent impulses.  157:664-675. 2014

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in parkinson's disease.  157:472-485. 2014

Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events.  156:170-182. 2014

XTryptophan biosynthesis protects mycobacteria from CD4 T-Cell-mediated Killing.  155. 2013

The somatic genomic landscape of glioblastoma.  155:462. 2013

XSpatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network.  154. 2013

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.  153:1266-1280. 2013

Dwelling on T cell fate decisions.  153:739-741. 2013

Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration.  151:1029-1041. 2012

A validated regulatory network for Th17 cell specification.  151:289-303. 2012

A role for small RNAs in DNA double-strand break repair..  149:101-112. 2012

Erratum: Generation of isogenic pluripotent stem cells differing exclusively at two early onset parkinson point mutations (Cell (2011) 146 (318-331)).  146:659. 2011

Generation of isogenic pluripotent stem cells differing exclusively at two early onset parkinson point mutations.  146:318-331. 2011

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies.  146:37-52. 2011

Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2.  146:53-66. 2011

miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts.  140:652-665. 2010

Cellular strategies for regulating DNA supercoiling: A single-molecule perspective.  142:519-530. 2010

Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition.  142:309-319. 2010

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation.  141:656-667. 2010

NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome.  142:218-229. 2010

Natural mutagenesis of human genomes by endogenous retrotransposons.  141:1253-1261. 2010

Role for IGFBP7 in senescence induction by BRAF.  141:746-747. 2010

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival.  139:573-586. 2009

NPR1 in Plant Defense: It's Not over 'til It's Turned over.  137:804-806. 2009

Collateral Damage from Antigen Receptor Gene Diversification.  135:1009-1012. 2008

The Immortal Strand Hypothesis: How Could It Work?.  133:21-23. 2008

Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7.  132:363-374. 2008

Stem Cells on Patrol.  131:842-844. 2007

ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes.  130:63-75. 2007

FOXP3 Is an X-Linked Breast Cancer Suppressor Gene and an Important Repressor of the HER-2/ErbB2 Oncogene.  129:1275-1286. 2007

CHD5 Is a Tumor Suppressor at Human 1p36.  128:459-475. 2007

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1.  125:1055-1067. 2006

Tracking RNA polymerase, one step at a time.  123:977-979. 2005

Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte.  123:321-334. 2005

Right place, right time, and only once: Replication initiation in metazoans.  123:13-24. 2005

Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.  122:351-363. 2005

Decoding Dopamine Signaling.  122:153-155. 2005

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.  119:861-872. 2004

DksA: A critical component of the transcription initiation machinery that potentiates the regulation of rRNA promoters by ppGpp and the initiating NTP.  118:311-322. 2004

Regulation through the secondary channel - Structural framework for ppGpp-DksA synergism during transcription.  118:297-309. 2004

Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene.  117:541-552. 2004

Structural basis for transcription regulation by alarmone ppGpp.  117:299-310. 2004

Structural basis for substrate selection by T7 RNA polymerase.  116:381-391. 2004

O-GlcNAc modification is an endogenous inhibitor of the proteasome.  115:715-725. 2003

A "dock, lock, and latch" structural model for a staphylococcal adhesin binding to fibrinogen.  115:217-228. 2003

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation.  112:779-791. 2003

Identification of a Wnt/Dvl/β-catenin → Pitx2 pathway mediating cell-type-specific proliferation during development.  111:673-685. 2002

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.  109:707-718. 2002

Drosophila fragile x-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function.  107:591-603. 2001

Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by Geminin.  106:287-296. 2001

Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase.  103:793-803. 2000

FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium.  101:729-739. 2000

The integrin αvβ6 binds and activates latent TGFβ1: A mechanism for regulating pulmonary inflammation and fibrosis.  96:319-328. 1999

Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center.  95:939-950. 1998

Thrombospondin-1 is a major activator of TGF-β1 in vivo.  93:1159-1170. 1998

Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.  91:753-763. 1997

Association of the origin recognition complex with heterochromatin and HP1 in higher eukaryotes.  91:311-323. 1997

Targeted disruption of the melanocortin-4 receptor results in obesity in mice.  88:131-141. 1997

Atomic model of a pyrimidine dimer excision repair enzyme complexed with a dna substrate: Structural basis for damaged DNA recognition.  83:773-782. 1995

Identification of an ER retrieval signal in a retroviral glycoprotein.  82:543-544. 1995

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel.  79:407-414. 1994

Atomic structure of the RuvC resolvase: A holliday junction-specific endonuclease from E. coli.  78:1063-1072. 1994

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.  72:971-983. 1993

A TBP complex essential for transcription from TATA-less but not TATA-containing RNA polymerase III promoters is part of the TFIIB fraction.  71:1029-1040. 1992

Protein traffic between distinct plasma membrane domains: Isolation and characterization of vesicular carriers involved in transcytosis.  64:81-89. 1991

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis.  63:1061-1072. 1990

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA^Lys mutation.  61:931-937. 1990

A 7 bp mutation converts a human RNA polymerase II snRNA promoter into an RNA polymerase III promoter.  58:55-67. 1989

Vaccinia virus produces late mRNAs by discontinuous synthesis.  50:153-162. 1987

Genetic linkage of von Recklinghausen neurofibromatosis to the nerve growth factor receptor gene.  49:589-594. 1987

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.  46:963-972. 1986

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins.  45:3-13. 1986

The host protein required for in vitro replication of poliovirus is a protein kinase that phosphorylates eukaryotic initiation factor-2.  40:913-921. 1985

Expression of hemolytically active murine fourth component of complement in transfected L cells.  37:569-576. 1984

Four unique genes required for β tubulin expression in vertebrates.  32:713-724. 1983

A UDP-glucose:Glycoprotein glucose-1-phosphotransferase in embryonic chicken neural retina.  31:739-748. 1982

Retinal ligatin recognizes glycoproteins bearing oligosaccharides terminating in phosphodiester-linked glucose.  28:813-820. 1982

Histone gene clusters of the newt notophthalmus are separated by long tracts of satellite DNA.  24:639-647. 1981

Identification of the gene and mRNA for the adenovirus terminal protein precursor.  23:497-508. 1981

SV40 gene expression is modulated by the cooperative binding of T antigen to DNA.  25:373-384. 1981

Identification and mapping of the transcriptional and translational products of the yeast plasmid, 2μ circle.  16:827-839. 1979

A supplementary adenoviral leader sequence and its role in messenger translation.  15:511-526. 1978

The spliced structures of adenovirus 2 fiber message and the other late mRNAs.  15:497-510. 1978

A map of cytoplasmic RNA transcripts from lytic adenovirus type 2, determined by electron microscopy of RNA:DNA hybrids.  11:819-836. 1977

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA.  12:1-8. 1977

Gene expression in chemically transformed mouse embryo cells: Selective enhancement of the expression of C type RNA tumor virus genes.  11:909-921. 1977