Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Mechanisms of TGFß in prostaglandin synthesis and sperm guidance in Caenorhabditis elegansDevelopmental Dynamics.  250:932-942. 2021
2020 Transcriptomic profiling of DAF-7/TGFΒ pathway mutants in C. ElegansGenes.  11. 2020
2020 Cranberry anti-cancer compounds and their uptake and metabolism: An updated reviewJournal of Berry Research.  10:1-10. 2020
2019 Signature profile of cyclooxygenase-independent F2 series prostaglandins in C. elegans and their role in sperm motilityScientific Reports.  9. 2019
2019 Cranberry phytochemicals and their cancer preventive properties. Journal of Berry ResearchJournal of Berry Research2019
2018 Unique Lipid Signatures of Extracellular Vesicles from the Airways of AsthmaticsScientific Reports.  8. 2018
2018 Comprehensive profiling of prostaglandins in human ovarian follicular fluid using mass spectrometryProstaglandins and Other Lipid Mediators.  134:7-15. 2018
2017 Erratum to: Mass spectrometric evidence for the modification of small molecules in a cobalt-60-irradiated rodent diet: Irradiation modifies the content of animal diet (Journal of Mass Spectrometry, (2017), 52, 8, (507-516), 10.1002/jms.3950)Journal of Mass Spectrometry.  52:707. 2017
2017 Mass spectrometric evidence for the modification of small molecules in a cobalt-60-irradiated rodent dietJournal of Mass Spectrometry.  52:507-516. 2017
2017 Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemiaJournal of Leukocyte Biology.  101:531-542. 2017
2017 Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signalingScientific Reports.  7. 2017
2016 Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cellsFood and Function.  7:4012-4019. 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  461-475. 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  51:ii-iii. 2016
2015 Comparative lipidomics of caenorhabditis elegans metabolic disease models by SWATH non-targeted tandem mass spectrometryMetabolites.  5:677-696. 2015
2014 Improved high sensitivity analysis of polyphenols and their metabolites by nano-liquid chromatography-mass spectrometryArchives of Biochemistry and Biophysics.  559:3-11. 2014
2014 Pharmacokinetics of equol, a soy isoflavone metabolite, changes with the form of equol (Dietary versus Intestinal Production) in ovariectomized ratsJournal of Agricultural and Food Chemistry.  62:1294-1300. 2014
2014 Acute and Chronic Kudzu Improves Plasma Glucose Tolerance in Non-Diabetic CD-1 Mice.Journal of Endocrinology and Diabetes Mellitus.  2:70-77. 2014
2014 Neurosensory perception of environmental cues modulates sperm motility critical for fertilizationScience.  344:754-757. 2014
2013 VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in Caenorhabditis elegansPLoS Genetics.  9. 2013
2013 Isoflavone metabolism in domestic cats (Felis catus): Comparison of plasma metabolites detected after ingestion of two different dietary forms of genistein and daidzeinJournal of Animal Science.  91:1295-1306. 2013
2013 Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry 2013
2013 A Heterogeneous Mixture of F-Series Prostaglandins Promotes Sperm Guidance in the Caenorhabditis elegans Reproductive TractPLoS Genetics.  9. 2013
2013 In nutrition, can we 'see' what is good for us?Advances in Nutrition.  4. 2013
2013 Ovariectomy lowers urine levels of unconjugated (+)-catechin, (-)-epicatechin, and their methylated metabolites in rats fed grape seed extractHormone Molecular Biology and Clinical Investigation.  16:129-138. 2013
2013 Prostaglandin extraction and analysis in Caenorhabditis elegansJournal of Visualized Experiments2013
2013 Quercetin prevents left ventricular hypertrophy in the Apo E knockout mouseRedox Biology.  1:381-386. 2013
2012 The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese micePhytomedicine.  20:17-23. 2012
2012 Carnitine palmitoyltransferase-1b deficiency aggravates pressure overload-induced cardiac hypertrophy caused by lipotoxicityCirculation.  126:1705-1716. 2012
2011 Dietary isoflavone absorption, excretion, and metabolism in captive cheetahs (Acinonyx jubatus)Journal of Zoo and Wildlife Medicine.  42:658-670. 2011
2011 Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometryJournal of Agricultural and Food Chemistry.  59:6682-6688. 2011
2011 Hemodynamic characteristics of midazolam, propofol, and dexmedetomidine in healthy volunteersJournal of Clinical Anesthesia.  23:218-223. 2011
2011 The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systemsFood and Function.  2:235-244. 2011
2011 Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent mannerNeuro-Oncology.  13:28-41. 2011
2011 The gap junctional protein INX-14 functions in oocyte precursors to promote C. elegans sperm guidanceDevelopmental Biology.  359:47-58. 2011
2010 Insulin/FOXO Signaling Regulates Ovarian Prostaglandins Critical for ReproductionDevelopmental Cell.  19:858-871. 2010
2010 Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: Potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescueAmerican Journal of Respiratory Cell and Molecular Biology.  43:607-616. 2010
2010 Flavonoids and age-related disease: Risk, benefits and critical windowsMaturitas.  66:163-171. 2010
2010 Simultaneous determination of 11 phytoestrogens in human serum using a 2 min liquid chromatography/tandem mass spectrometry method 2010
2009 Chronic dietary kudzu isoflavones improve components of metabolic syndrome in stroke-prone spontaneously hypertensive ratsJournal of Agricultural and Food Chemistry.  57:7268-7273. 2009
2009 Liquid chromatography tandem mass spectrometry identification of proanthocyanidins in rat plasma after oral administration of grape seed extractPhytomedicine.  16:233-243. 2009
2009 Tissue distribution of puerarin and its conjugated metabolites in rats assessed by liquid chromatography-tandem mass spectrometryPhytomedicine.  16:65-71. 2009
2008 A liquid chromatography mass spectrometry assay for determination of PD168393, a specific and irreversible inhibitor of erbB membrane tyrosine kinases, in rat serum 2008
2008 Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers 2008
2008 Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and femalesGender Medicine.  5. 2008
2007 Genistein attenuates the hypertensive effects of dietary NaCl in hypertensive male ratsEndocrinology.  148:5396-5402. 2007
2007 Metabolism and bioavailability of flavonoids in chemoprevention: Current analytical strategies and future prospectusMolecular Pharmaceutics.  4:846-864. 2007
2007 Pharmacokinetic study of puerarin in rat serum by liquid chromatography tandem mass spectrometryBiomedical Chromatography.  21:410-414. 2007
2007 Identification of isoflavone glycosides in pueraria lobata cultures by tandem mass spectrometryPhytochemical Analysis.  18:50-59. 2007
2006 Applications of LC-MS in the study of the uptake, distribution, metabolism and excretion of bioactive polyphenols from dietary supplementsLife Sciences.  78:2054-2059. 2006
2006 Differential biliary excretion of genistein metabolites following intraduodenal and intravenous infusion of genistin in female rats 2006
2005 Contrasting effects of puerarin and daidzin on glucose homeostasis in miceJournal of Agricultural and Food Chemistry.  53:8760-8767. 2005
2005 Antihypertensive and cognitive effects of grape polyphenols in estrogen-depleted, female, spontaneously hypertensive rats 2005
2005 Electrospray tandem mass spectrometric analysis of zeaxanthin and its oxidation productsJournal of Mass Spectrometry.  40:916-923. 2005
2005 Current progress in the use of traditional medicines and nutraceuticalsCurrent Opinion in Plant Biology.  8:324-328. 2005
2005 Metabolism of phytoestrogen conjugatesMethods in Enzymology.  400:316-342. 2005
2004 Mass spectrometric methods for the determination of flavonoids in biological samplesFree Radical Biology and Medicine.  37:1324-1350. 2004
2004 Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometryJournal of Agricultural and Food Chemistry.  52:3708-3712. 2004
2003 Neutrophil myeloperoxidase chlorinates and nitrates soy isoflavones and enhances their antioxidant propertiesFree Radical Biology and Medicine.  35:1417-1430. 2003
2003 Profiling and quantification of isoflavonoids in kudzu dietary supplements by high-performance liquid chromatography and electrospray ionization tandem mass spectrometryJournal of Agricultural and Food Chemistry.  51:4213-4218. 2003
2003 Mass spectrometric methods for the analysis of chlorinated and nitrated isoflavonoids: A novel class of biological metabolitesJournal of Mass Spectrometry.  38:764-771. 2003
2003 Novel diarylheptanoids of Alpinia blepharocalyx.Current Topics in Medicinal Chemistry.  3:203-225. 2003
2002 Rapid screening and identification of cytochalasins by electrospray tandem mass spectrometryJournal of Mass Spectrometry.  37:283-291. 2002
2002 Review of the methods used in the determination of phytoestrogens 2002
2001 Taxines from the needles of Taxus wallichiana 2001
2001 Detection and partial structure elucidation of basic taxoids from Taxus wallichiana by electrospray ionization tandem mass spectrometryAnalytical Chemistry.  73:3583-3589. 2001
2000 Distribution, metabolism and excretion of butylidenephthalide of Ligustici chuanxiong rhizoma in hairless mouse after dermal applicationJournal of Ethnopharmacology.  71:401-409. 2000
1999 New diarylheptanoid from the seeds of Alpinia blepharocalyx 1999
1998 Tribulusamide A and B, new hepatoprotective lignanamides from the fruits of Tribulus terrestris: Indications of cytoprotective activity in murine hepatocyte culture 1998
1998 Chemical constituents of Brazilian propolis and their cytotoxic activitiesJournal of Natural Products.  61:896-900. 1998
1998 Calyxin H, epicalyxin H and blepharocalyxins A and B, novel diarylheptanoids from the seeds of Alpinia blepharocalyxJournal of Natural Products.  61:212-216. 1998
1998 Antiosteoporotic activity of the stems of Sambucus sieboldianaBiological and Pharmaceutical Bulletin.  21:594-598. 1998
1998 Inhibitory effect of diarylheptanoids on nitric oxide production in activated murine macrophagesBiological and Pharmaceutical Bulletin.  21:371-374. 1998
1998 Novel Diarylheptanoids from the Seeds of Alpinia blepharocalyx: Revised Structure of Calyxin A 1998
1997 Six novel diarylheptanoids bearing chalcone or flavanone moiety from the seeds of Alpinia blepharocalyx 1997
1996 Blepharocalyxins A and B, novel diarylheptanoids from Alpinia blepharocalyx, and their inhibitory effect on NO formation in murine macrophages 1996
1996 Hepatoprotective effects of Panax notoginseng: Ginsenosides -Re and -Rg(1) as its active constituents in D-galactosamine/lipopolysaccharide-induced liver injury.Phytomedicine.  2:297-303. 1996
1994 Three novel diarylheptanoids, calyxin a, calyxin b, and 3-epi-calyxin b from a chinese crude drug “yunnan cao kou” (alpinia Blepharocalyx K. Schum.) 1994

Chapter

Year Title Altmetric
2018 Analyzing ingredients in dietary supplements and their metabolites.  337-346. 2018
2013 Pharmacological effects of cordyceps and its bioactive compounds.  453-468. 2013
2013 Uptake and Metabolism of Dietary Proanthocyanidins.  553-560. 2013
2009 Recent advances in traditional medicines and dietary supplements.  533-546. 2009
2006 Soy Isoflavones.  559-571. 2006

Investigator On

  • Cohort Study of Cancer-Inhibitory Dietary Factors in Men  awarded by VANDERBILT UNIVERSITY
  • DHA Mechanisms in Obesity-Mediated Cardiac Remodeling Post-Myocardial Infarction  awarded by NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH/NIH/DHHS
  • Ethnic Differences in Responses to Painful Stimuli  awarded by University of Florida
  • Genetic Regulation of Unconventional Prostaglandin Metabolism  awarded by National Institute of General Medical Sciences/NIH/DHHS
  • Novel Treatment of NF-1 Associated Malignant Peripheral Nerve Sheath Tumors  awarded by National Cancer Institute/NIH/DHHS
  • Postnatal Origin of Amyotrophic Lateral Sclerosis (MDA381893)  awarded by Muscular Dystrophy Association
  • Prostaglandins in C. Elegans Fertilization  awarded by National Institute of General Medical Sciences/NIH/DHHS
  • UAB -UCSD O'Brien Core Center for Acute Kidney Injury Research - Core C  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research - Core C  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Core Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Core Center for Acute Kidney Injury Research - Administrative Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research - Core C  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Education And Training

  • Doctor of Philosophy in Pharmacy, Pharmaceutical Sciences, and Administration, Toyama University of International Studies 2000
  • Full Name

  • Jeevan Prasain