Selected Publications

Academic Article

Year Title Altmetric
2022 PET/MRI in Pediatric Neuroimaging: Primer for Clinical PracticeAmerican Journal of Neuroradiology.  43:938-943. 2022
2022 Dynamic Amyloid PET: Relationships to 18F-Flortaucipir Tau PET MeasuresJournal of Nuclear Medicine.  63:287-293. 2022
2021 Utility of 18F-fluciclovine PET/MRI for staging newly diagnosed high-risk prostate cancer and evaluating response to initial androgen deprivation therapy: A prospective single-arm pilot studyAmerican Journal of Roentgenology.  217:720-729. 2021
2021 Production of [89Zr]Oxinate4 and cell radiolabeling for human useJournal of Labelled Compounds and Radiopharmaceuticals.  64:209-216. 2021
2021 Global access to medical imaging and nuclear medicine 2021
2021 Synchronous Malignancies Identified by 18F-fluciclovine Positron Emission Tomography for Prostate Cancer: Case Series and Mini-ReviewClinical Genitourinary Cancer.  19:e37-e40. 2021
2021 Racial Differences in Alzheimer's Disease Specialist Encounters Are Associated with Usage of Molecular Imaging and Dementia Medications: An Enterprise-Wide Analysis Using i2b2Journal of Alzheimer's Disease.  79:543-557. 2021
2021 Real-Time Gain Control of PET Detectors and Evaluation with Challenging RadionuclidesIEEE Transactions on Medical Imaging.  40:71-80. 2021
2020 Dynamic 18F-FDOPA-PET/MRI for the preoperative evaluation of gliomas: Correlation with stereotactic histopathologyNeuro-oncology practice.  7:656-667. 2020
2020 Measurement of blood flow in myocardial layers: A step toward comprehensive physiological evaluationJournal of Nuclear Cardiology.  27:1675-1678. 2020
2020 Leucocyte count predicts cardiovascular risk in heart failure with preserved ejection fraction: insights from TOPCAT AmericasESC Heart Failure.  7:1676-1687. 2020
2020 FDG-PET/CT diagnosis of aortitis and pseudoaneurysmsJournal of Nuclear Cardiology.  27:362-365. 2020
2020 The role of metabolic plasticity in blood and brain stem cell pathophysiologyCancer Research.  80:5-16. 2020
2019 Myocardial blood flow measures using cardiac positron emission tomography: Software comparisonsJournal of Nuclear Cardiology.  26:2013-2017. 2019
2019 Heterogeneity Diffusion Imaging of gliomas: Initial experience and validationPLoS One.  14. 2019
2019 Feasibility of Dose Escalating [18F]fluciclovine Positron Emission Tomography Positive Pelvic Lymph Nodes During Moderately Hypofractionated Radiation Therapy for High-Risk Prostate CancerAdvances in Radiation Oncology.  4:649-658. 2019
2019 Recognizing and minimizing artifacts at ct, mri, us, and molecular imaging 2019
2019 Biomarker Localization, Analysis, Visualization, Extraction, and Registration (BLAzER) Workflow for Research and Clinical Brain PET Applications 2019
2019 Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [ 18 F]FDG: version 1.0European Journal of Nuclear Medicine and Molecular Imaging.  46:540-557. 2019
2019 Patient Demographics and Referral Patterns for [F-18]Fluciclovine-PET Imaging at a Tertiary Academic Medical CenterJournal of the American College of Radiology.  16:315-320. 2019
2019 Biomarker Localization, Analysis, Visualization, Extraction, and Registration (BLAzER) Methodology for Research and Clinical Brain PET ApplicationsJournal of Alzheimer's Disease.  70:1241-1257. 2019
2019 Current and future imaging methods for evaluating response to immunotherapy in neuro-oncologyTheranostics.  9:5085-5104. 2019
2018 Imaging melphalan therapy response in preclinical extramedullary multiple myeloma with 18F-FDOPA and 18F-FDG PETJournal of Nuclear Medicine.  59:1551-1557. 2018
2018 Investigational PET tracers for high-grade gliomas 2018
2018 Role of PET imaging for biochemical recurrence following primary treatment for prostate cancerTranslational andrology and urology.  7:S462-S476. 2018
2018 18F-FDOPA PET/MRI for monitoring early response to bevacizumab in children with recurrent brain tumorsNeuro-oncology practice.  5:28-36. 2018
2018 PET/MR Imaging in Head and Neck Cancer: Current Applications and Future DirectionsMagnetic Resonance Imaging Clinics of North America.  26:167-178. 2018
2018 Amino acid uptake measured by [ 18 F]AFETP increases in response to arginine starvation in ASS1-deficient sarcomasTheranostics.  8:2107-2116. 2018
2018 Practical Considerations for Clinical PET/MR ImagingPET Clinics.  13:97-112. 2018
2017 Lymph node imaging in initial staging of prostate cancer: An overview and update.World Journal of Radiology.  9:389-399. 2017
2017 ACR and SNMMI Joint Credentialing Statement for PET/MRI of the Body.Journal of Nuclear Medicine.  58:1174-1176. 2017
2017 Evaluation of attenuation correction in cardiac PET using PET/MRJournal of Nuclear Cardiology.  24:839-846. 2017
2017 Practical Considerations for Clinical PET/MR ImagingMagnetic Resonance Imaging Clinics of North America.  25:281-296. 2017
2017 Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers.Cell Reports.  18:991-1004. 2017
2017 Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein.Nature Communications.  8:14152. 2017
2016 Indeterminate Findings on Oncologic PET/CT: What Difference Does PET/MRI Make?Nuclear Medicine and Molecular Imaging.  50:292-299. 2016
2016 18F-Fluciclovine (FACBC) and its potential use for breast cancer imagingJournal of Nuclear Medicine.  57:1329-1330. 2016
2016 Conspicuity of FDG-Avid Osseous Lesions on PET/MRI Versus PET/CT: a Quantitative and Visual Analysis.Nuclear Medicine and Molecular Imaging.  50:228-239. 2016
2016 Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy.JAMA Neurology.  73:1070-1077. 2016
2016 Clinical application of PET/MRI in oncologyJournal of Magnetic Resonance Imaging.  44:265-276. 2016
2016 Evaluation of diagnostic performance of whole-body simultaneous PET/MRI in pediatric lymphoma 2016
2016 SNMMI Procedure Standard/EANM Practice Guideline for Amyloid PET Imaging of the Brain 1.0.Journal of Nuclear Medicine.  57:1316-1322. 2016
2016 The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging 2016
2016 Impact of MR-Based Attenuation Correction on Neurologic PET Studies.Journal of Nuclear Medicine.  57:913-917. 2016
2016 Effect of α-Methyl versus α-Hydrogen Substitution on Brain Availability and Tumor Imaging Properties of Heptanoic [F-18]Fluoroalkyl Amino Acids for Positron Emission Tomography (PET)Journal of Medicinal Chemistry.  59:3515-3531. 2016
2016 PET/MRI: Emerging Clinical Applications in Oncology.Academic Radiology.  23:220-236. 2016
2016 Multimodality Review of Amyloid-related Diseases of the Central Nervous System. 2016
2015 Synthesis and Biological Evaluation of (S)-Amino-2-methyl-4-[76Br]bromo-3-(E)-butenoic Acid (BrVAIB) for Brain Tumor ImagingJournal of Medicinal Chemistry.  58:8542-8552. 2015
2015 PET/MRI for the body imager: abdominal and pelvic oncologic applications.Abdominal radiology (New York).  40:1387-1404. 2015
2015 Synthesis, Radiolabeling, and Biological Evaluation of (R)- and (S)-2-Amino-5-[(18)F]fluoro-2-methylpentanoic Acid ((R)-, (S)-[(18)F]FAMPe) as Potential Positron Emission Tomography Tracers for Brain Tumors.Journal of Medicinal Chemistry.  58:3817-3829. 2015
2015 Imaging biomarkers associated with cognitive decline: a review.Biological Psychiatry.  77:685-692. 2015
2015 American College of Radiology and Society of Nuclear Medicine and Molecular Imaging Joint Credentialing Statement for PET/MR Imaging: Brain.Journal of Nuclear Medicine.  56:642-645. 2015
2015 Beyond whole-body imaging: Advanced imaging techniques of PET/MRIClinical Nuclear Medicine.  40:e88-e95. 2015
2015 Facile purification and click labeling with 2-[18F]fluoroethyl azide using solid phase extraction cartridges. 2015
2015 Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors.Disease Markers.  2015:874904. 2015
2015 System a amino acid transport-targeted brain and systemic tumor PET imaging agents 2-amino-3-[(18)F]fluoro-2-methylpropanoic acid and 3-[(18)F]fluoro-2-methyl-2-(methylamino)propanoic acid.Nuclear Medicine and Biology.  42:8-18. 2015
2014 Attenuation Effects of MR Headphones During Brain PET/MR Studies.Journal of Nuclear Medicine Technology.  42:93-100. 2014
2014 An overview of nuclear medicine studies for urgent and emergent indications.Seminars in Roentgenology.  49:210-224. 2014
2014 Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: A preliminary PET studyPsychiatry Research.  221:231-239. 2014
2014 Whole-body simultaneous positron emission tomography (PET)-MR: optimization and adaptation of MRI sequences.Journal of Magnetic Resonance Imaging.  39:259-268. 2014
2014 Imaging evaluation of CSF shunts.American Journal of Roentgenology.  202:38-53. 2014
2013 Imaging the L-Type Amino Acid Transporter-1 (LAT1) with Zr-89 ImmunoPETPLoS One.  8. 2013
2013 18F-AFETP, 18F-FET, and 18F-FDG imaging of mouse DBT gliomas.Journal of Nuclear Medicine.  54:1120-1126. 2013
2013 Radiolabeled amino acids for oncologic imaging.Journal of Nuclear Medicine.  54:1007-1010. 2013
2013 Radiosynthesis and biological evaluation of alpha-[F-18]fluoromethyl phenylalanine for brain tumor imaging.Nuclear Medicine and Biology.  40:498-506. 2013
2013 Overview of PET Tracers for Brain Tumor Imaging.PET Clinics.  8:129-146. 2013
2013 Advances in diagnostic testing for Alzheimer disease.Missouri medicine.  110:401-405. 2013
2013 Fluorine-18 labeled amino acids for oncologic imaging with positron emission tomography.Current Topics in Medicinal Chemistry.  13:871-891. 2013
2013 Nuclear medicine in the acute clinical setting: indications, imaging findings, and potential pitfalls. 2013
2012 Commentary. 2012
2012 Radiohalogenated nonnatural amino acids as PET and SPECT tumor imaging agents.Medicinal Research Reviews.  32:868-905. 2012
2010 Click synthesis and biologic evaluation of (R)- and (S)-2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid for brain tumor imaging with positron emission tomography.Molecular Imaging.  9:329-342. 2010
2010 Synthesis, radiolabeling, and biological evaluation of (R)- and (S)-2-amino-3-[(18)F]fluoro-2-methylpropanoic acid (FAMP) and (R)- and (S)-3-[(18)F]fluoro-2-methyl-2-N-(methylamino)propanoic acid (NMeFAMP) as potential PET radioligands for imaging brain tumors.Journal of Medicinal Chemistry.  53:876-886. 2010
2008 Non-natural amino acids for tumor imaging using positron emission tomography and single photon emission computed tomography.Cancer and Metastasis Reviews.  27:555-573. 2008
2007 Preparation of antidepressants for use in preclinical research.International Journal of Neuropsychopharmacology.  10:759-763. 2007
2006 Evaluation of carbon-11-labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a potential radioligand for imaging the serotonin transporter by PET.Journal of Medicinal Chemistry.  49:942-946. 2006
2005 Semi-automated preparation of the dopamine transporter ligand [(18)F]FECNT for human PET imaging studies.Applied Radiation and Isotopes.  63:353-361. 2005
2005 Synthesis and biological evaluation of trans-3-phenyl-1-indanamines as potential norepinephrine transporter imaging agents.Nuclear Medicine and Biology.  32:593-605. 2005
2005 Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.Journal of Medicinal Chemistry.  48:4254-4265. 2005
2005 Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.Nuclear Medicine and Biology.  32:75-86. 2005
2004 Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.Nuclear Medicine and Biology.  31:705-718. 2004
2004 Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.Journal of Medicinal Chemistry.  47:1122-1135. 2004
2003 Synthesis and evaluation of 2-amino-4-[(18)F]fluoro-2-methylbutanoic acid (FAMB): relationship of amino acid transport to tumor imaging properties of branched fluorinated amino acids.Nuclear Medicine and Biology.  30:477-490. 2003
2003 Improved synthesis of anti-[18F]FACBC: improved preparation of labeling precursor and automated radiosynthesis.Applied Radiation and Isotopes.  58:657-666. 2003
2003 Stereochemistry in Drug Action.The primary care companion for CNS disorders.  5:70-73. 2003
2003 Synthesis and characterization of iodine-123 labeled 2beta-carbomethoxy-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane. A ligand for in vivo imaging of serotonin transporters by single-photon-emission tomography.Journal of Medicinal Chemistry.  46:925-935. 2003
2002 Radiolabeled amino acids for tumor imaging with PET: radiosynthesis and biological evaluation of 2-amino-3-[18F]fluoro-2-methylpropanoic acid and 3-[18F]fluoro-2-methyl-2-(methylamino)propanoic acid.Journal of Medicinal Chemistry.  45:2240-2249. 2002
2002 Synthesis of syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC), potential PET ligands for tumor detection.Journal of Medicinal Chemistry.  45:2250-2259. 2002
2001 Radioligands for PET and SPECT Imaging of the central noradrenergic system. 2001


Year Title Altmetric
2018 PET/MRI for clinical pediatric oncologic imaging.  401-432. 2018
2017 Overview of positron-emission tomography tracers for metabolic imaging.  47-80. 2017

Investigator On

  • Detecting Neuroinflammation in Fibromyalgia with the Positron Emission Tomography (PET) Radioligand [18] DPA-714  awarded by American Fibromyalgia Syndrome Association
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group
  • ECOG-ACRIN Purchase Service Agreement  awarded by Eastern Cooperative Oncology Group
  • FDG PET to Assess Therapeutic Response in Patients with Bone-Dominant Metastatic Breast Cancer, FEATURE R20-080  awarded by ECOG-ACRIN CANCER RESEARCH GROUP
  • Innate and Adaptive Immunity in Parkinson Disease  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Innate and Adaptive Immunity in Parkinson Disease - Core B: Clinical Research Core  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Innate and Adaptive Immunity in Parkinson Disease - Project 1: Role of Innate Immune Cells in Human Parkinson Disease  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Innate and Adaptive Immunity in Parkinson Disease - Project 5: Innate and Adaptive Immunity in Lewy Body Dementia  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Measuring Neuroinflammation in Chronic Fatigue Syndrome with Whole-brain Magnetic Resonance Spectroscopy  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • NCTN Deep South Research Consortium  awarded by National Cancer Institute/NIH/DHHS
  • Personalizing Immunotherapy in HER2+ Breast Cancer through Quantitative Imaging  awarded by National Cancer Institute/NIH/DHHS
  • Private Grant  awarded by NAVIDEA BIOPHARMACEUTICALS, INC.
  • Private Grant  awarded by BLUE EARTH DIAGNONSTICS LTD ^
  • Private Grant  awarded by BLUE EARTH DIAGNONSTICS LTD ^
  • Private Grant  awarded by Genzyme Corporation
  • Private Grant  awarded by CURIUM US LLC
  • Radiolabeled Antibodies Targeting LAT1 for Imaging and Therapy of Prostate Cancer  awarded by National Cancer Institute/NIH/DHHS
  • Site-Specific Immune Cell Activation Detection for Improving Individualized Cancer Immunotherapy  awarded by NIH - OFFICE OF THE DIRECTOR
  • UAB Alzheimer's Disease Research Center  awarded by National Institute on Aging/NIH/DHHS
  • UAB Alzheimer's Disease Research Center - Clinical Core  awarded by NIH - National Institutes of Health/DHHS
  • UAB Research Education Program for Residents and Fellows in Neuroscience  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • UAB Research and Education Program in Neuroscience  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Viability Testing of Immune Cells Extracted from Human Blood Samples  awarded by ME RESEARCH UK
  • Education And Training

  • Emory University SOM, Internship
  • Washington University SOM, Residency
  • Washington University SOM, Postdoctoral Fellowship
  • Doctor of Medicine, Emory University 2004
  • Doctor of Philosophy in Biological and Biomedical Sciences, Emory University 2003
  • Full Name

  • Jonathan McConathy