Selected Publications

Academic Article

Year Title Altmetric
2022 A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesionsEMBO Molecular Medicine.  14. 2022
2022 Mycobacterium tuberculosis DosS binds H2S through its Fe3+ heme iron to regulate the DosR dormancy regulonRedox Biology.  52. 2022
2021 Micro-computed tomography analysis of the human tuberculous lung reveals remarkable heterogeneity in three-dimensional granuloma morphologyAmerican Journal of Respiratory and Critical Care Medicine.  204:583. 2021
2021 Mycobacterium tuberculosis h2s functions as a sink to modulate central metabolism, bioenergetics, and drug susceptibilityAntioxidants.  10. 2021
2021 Mycobacterium tuberculosis H2S functions as a sink to modulate central metabolism, bioenergetics, and drug susceptibility 2021
2020 Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosisNature Communications.  11. 2020
2020 Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesisNature Communications.  11. 2020
2020 The Role of Host-Generated H2S in Microbial Pathogenesis: New Perspectives on TuberculosisFrontiers in Cellular and Infection Microbiology.  10. 2020
2019 Erratum: Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis (Cell Reports (2018) 25(7) (1938–1952.e5), (S2211124718316772), (10.1016/j.celrep.2018.10.073))Cell Reports.  28:3286. 2019
2018 Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human TuberculosisCell Reports.  25:1938-1952.e5. 2018
2018 Ferritin H deficiency in myeloid compartments dysregulates host energy metabolism and increases susceptibility to Mycobacterium tuberculosis infectionFrontiers in Immunology.  9. 2018
2016 The emerging role of gasotransmitters in the pathogenesis of tuberculosisNitric Oxide: Biology and Chemistry.  59:28-41. 2016
2016 Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosisCell Reports.  14:572-585. 2016
2014 Fiber-modified adenovirus for central nervous system Parkinson's disease gene therapyViruses.  6:3293-3310. 2014
2013 An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene TransferPLoS One.  8. 2013
2012 Iron sulfur cluster proteins and microbial regulation: Implications for understanding tuberculosisCurrent Opinion in Chemical Biology.  16:45-53. 2012
2010 An adenoviral vector expressing human adenovirus 5 and 3 fiber proteins for targeting heterogeneous cell populationsVirology.  407:196-205. 2010
2010 Transduction of brain dopamine neurons by adenoviral vectors is modulated by car expression: Rationale for tropism modified vectors in PD gene therapyPLoS One.  5:1-9. 2010
2010 Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domainsJournal of Virology.  84:10558-10568. 2010
2009 A strategy for adenovirus vector targeting with a secreted single chain antibodyPLoS One.  4. 2009
2009 Crystallization of the head and galectin-like domains of porcine adenovirus isolate NADC-1 fibreActa Crystallographica Section F: Structural Biology Communications.  65:1149-1152. 2009
2009 A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivoVaccine.  27:7116-7124. 2009
2008 Enhanced gene delivery to human primary endothelial cells using tropism-modified adenovirus vectorsOpen Gene Therapy Journal.  1:7-11. 2008
2008 Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus CapsidJournal of Molecular Biology.  383:923-934. 2008
2008 A role for multidrug resistance protein 4 (MRP4; ABCC4) in human dendritic cell migrationBlood.  112:2353-2359. 2008
2008 Characterization of infectivity of knob-modified adenoviral vectors in glioma.Cancer Biology and Therapy.  7:786-793. 2008
2008 Characterization of infectivity of knob-modified adenoviral vectors in gliomaCancer Biology and Therapy.  7:788-795. 2008
2007 Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro modelsNeuro-Oncology.  9:280-290. 2007
2007 A mosaic fiber adenovirus serotype 5 vector containing reovirus σ1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathwayClinical Cancer Research.  13:2777-2783. 2007
2007 Contrasting effects of human, canine, and hybrid adenovirus vectors on the phenotypical and functional maturation of human dendritic cells: Implications for clinical efficacyJournal of Virology.  81:3272-3284. 2007
2007 Novel recombinant adenoviral vector that targets the interleukin-13 receptor α2 chain permits effective gene transfer to malignant gliomaHuman gene therapy. Clinical development.  18:118-129. 2007
2006 Transductional targeting of adenovirus vectors for gene therapyCancer Gene Therapy.  13:830-844. 2006
2006 An adenovirus serotype 5 vector with fibers derived from ovine atadenovirus demonstrates CAR-independent tropism and unique biodistribution in miceVirology.  350:103-115. 2006
2006 Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells 2006
2006 An adenovirus vector with a chimeric fiber incorporating stabilized single chain antibody achieves targeted gene delivery 2006
2005 A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy 2005
2005 In vivo analysis of a genetically modified adenoviral vector targeted to human CD40 using a novel transient transgenic modelJournal of Gene Medicine.  7:1517-1525. 2005
2005 Reovirus σ1 fiber incorporated into adenovirus serotype 5 enhances infectivity via a CAR-independent pathwayBiochemical and Biophysical Research Communications.  335:205-214. 2005
2005 Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors 2005
2005 Mesothelin-mediated targeting of adenoviral vectors for ovarian cancer gene therapy 2005
2004 An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropismVirology.  324:103-116. 2004
2004 Transductional and transcriptional targeting of adenovirus for clinical applications 2004
2003 A mosaic adenovirus possessing serotype Ad5 and serotype Ad3 knobs exhibits expanded tropismVirology.  309:282-293. 2003
2002 A model system for the design of armed replicating adenoviruses using p53 as a candidate transgeneMolecular Cancer Therapeutics.  1:321-328. 2002
2001 Differential NF-κB regulation of bcl-x gene expression in hippocampus and basal forebrain in response to hypoxiaJournal of Neuroscience Research.  64:223-234. 2001
2001 Transcriptional regulation of the BCL-X gene by NF-κB is an element of hypoxic responses in the rat brainNeurochemical Research.  26:647-659. 2001
2000 Identification and characterization of nuclear factor κB binding sites in the murine bcl-x promoterJournal of Neurochemistry.  75:1377-1389. 2000
2000 NGF-mediated alteration of NF-κB binding activity after partial immunolesions to rat cholinergic basal forebrain neuronsInternational Journal of Developmental Neuroscience.  18:455-468. 2000
2000 One Path to Cell Death in the Nervous SystemNeurochemical Research.  25:1373-1383. 2000
1994 Mutagenesis of the cyclic AMP receptor protein of Escherichia coli: Targeting positions 83, 127 and 128 the cyclic nucleotide binding pocketNucleic Acids Research.  22:2894-2901. 1994


Year Title Altmetric
2021 Chapter 4: Modified Adenoviruses for Gene Therapy.  69-78. 2021

Education And Training

  • University of Alabama at Birmingham Division of Human Gene Therapy, Postdoctoral Fellowship
  • Doctor of Philosophy in Cell / Cellular and Molecular Biology, The University of Texas Medical Branch 2000
  • Bachelor of Science or Mathematics in Chemistry, Texas Tech University 1994
  • Full Name

  • Joel Glasgow