Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Determinants of metabolic syndrome and its prognostic implications among stroke patients in Africa: Findings from the Stroke Investigative Research and Educational Network (SIREN) studyJournal of the Neurological Sciences.  441. 2022
2022 Habitual Intake of Marine-Derived n-3 PUFAs is Inversely Associated with a Cardiometabolic Inflammatory Profile in Yup'ik Alaska Native People 2022
2022 Mendelian randomization in the multivariate general linear model frameworkGenetic Epidemiology.  46:17-31. 2022
2022 Risk Factor Characterization of Ischemic Stroke Subtypes Among West Africans.Stroke.  53:134-144. 2022
2021 Genetic Contributors of Incident Stroke in 10,700 African Americans With Hypertension: A Meta-Analysis From the Genetics of Hypertension Associated Treatments and Reasons for Geographic and Racial Differences in Stroke StudiesFrontiers in Genetics.  12. 2021
2021 Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci 2021
2021 Genetic variation in genes regulating skeletal muscle regeneration and tissue remodelling associated with weight loss in chronic obstructive pulmonary diseaseJournal of Cachexia, Sarcopenia and Muscle.  12:1803-1817. 2021
2021 Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of agingGenome Biology.  22. 2021
2021 Genomic alterations associated with mutational signatures, DNA damage repair and chromatin remodeling pathways in cervical carcinomanpj Genomic Medicine.  6. 2021
2021 A 6-CpG validated methylation risk score model for metabolic syndrome: The HyperGEN and GOLDN studiesPLoS One.  16. 2021
2021 Genomics of postprandial lipidomics in the genetics of lipid-lowering drugs and diet network studyNutrients.  13. 2021
2021 Predicting the Probability of Chlamydia Reinfection in African American Women Using Immunologic and Genetic Determinants in a Bayesian ModelSexually Transmitted Diseases.  48:813-818. 2021
2021 A Novel Afrocentric Stroke Risk Assessment Score: Models from the Siren StudyJournal of Stroke and Cerebrovascular Diseases.  30. 2021
2021 Influence of age on links between major modifiable risk factors and stroke occurrence in West AfricaJournal of the Neurological Sciences.  428. 2021
2021 Genomic characterization and therapeutic targeting of hpv undetected cervical carcinomasCancers.  13. 2021
2021 A novel Mendelian randomization method with binary risk factor and outcomeGenetic Epidemiology.  45:549-560. 2021
2021 Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries 2021
2021 The copy number variation and stroke (CaNVAS) risk and outcome studyPLoS One.  16. 2021
2021 Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes (Nature, (2020), 586, 7831, (763-768), 10.1038/s41586-020-2819-2)Nature.  591:E27. 2021
2021 Whole-Exome Sequencing and hiPSC Cardiomyocyte Models Identify MYRIP, TRAPPC11, and SLC27A6 of Potential Importance to Left Ventricular Hypertrophy in an African Ancestry PopulationFrontiers in Genetics.  12. 2021
2021 Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African AmericansEpigenetics.  16:862-875. 2021
2020 Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1AAmerican Journal of Clinical Nutrition.  112:1200-1211. 2020
2020 Inherited causes of clonal haematopoiesis in 97,691 whole genomesNature.  586:763-768. 2020
2020 Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scaleNature Genetics.  52:969-983. 2020
2020 A lipidome-wide association study of the lipoprotein insulin resistance indexLipids in Health and Disease.  19:153. 2020
2020 Genetic Admixture and Survival in Diverse Populations with Pulmonary Arterial HypertensionAmerican Journal of Respiratory and Critical Care Medicine.  201:1407-1415. 2020
2020 Heme metabolism genes Downregulated in COPD CachexiaRespiratory Research.  21. 2020
2020 Salivary AMY1 Copy Number Variation Modifies Age-Related Type 2 Diabetes Risk 2020
2020 Unraveling the risk factors for spontaneous intracerebral hemorrhage among West AfricansNeurology.  94:e998-e1012. 2020
2020 Erratum: Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infection (BMC Infectious Diseases (2019) 19 (1046) DOI: 10.1186/s12879-019-4681-0)BMC Infectious Diseases.  20. 2020
2020 The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in GreenlandersPLoS Genetics.  16. 2020
2019 Genetic risk of Spontaneous intracerebral hemorrhage: Systematic review and future directionsJournal of the Neurological Sciences.  407. 2019
2019 Association of CMV genomic mutations with symptomatic infection and hearing loss in congenital CMV infectionBMC Infectious Diseases.  19. 2019
2019 Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African AmericansMolecular Genetics and Genomic Medicine.  7. 2019
2019 Echocardiographic Abnormalities and Determinants of 1-Month Outcome of Stroke Among West Africans in the SIREN StudyJournal of the American Heart Association.  8. 2019
2019 Differential Impact of Risk Factors on Stroke Occurrence Among Men Versus Women in West Africa: The SIREN StudyStroke.  50:820-827. 2019
2019 Genetic influences on susceptibility to rheumatoid arthritis in African-AmericansHuman Molecular Genetics.  28:858-874. 2019
2019 Identification of gene variants associated with melanocyte stem cell differentiation in mice predisposed for hair graying 2019
2019 Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic TraitsAmerican Journal of Human Genetics.  104:112-138. 2019
2019 A Systematic Scoping Review of Surgically Manipulated Adipose Tissue and the Regulation of Energetics and Body Fat in AnimalsObesity.  27:1404-1417. 2019
2019 An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipidsFrontiers in Genetics.  10. 2019
2019 Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populationsPLoS Genetics.  15. 2019
2018 Disentangling associations between DNA methylation and blood lipids: A Mendelian randomization approachBMC Proceedings.  12. 2018
2018 Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic populationDiabetologia.  61:2005-2015. 2018
2018 An introduction to Mendelian randomization with applications in neurologyMultiple Sclerosis and Related Disorders.  24:72-78. 2018
2018 Single molecule mtDNA fiber FISH for analyzing numtogenesisAnalytical Biochemistry.  552:45-49. 2018
2018 Biobanking in a Challenging African Environment: Unique Experience from the SIREN Project.Biopreservation and Biobanking.  16:217-232. 2018
2018 Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN studyClinical Epigenetics.  10. 2018
2018 Epigenome-wide association study of metabolic syndrome in African-American adultsClinical Epigenetics.  10. 2018
2018 APOL1, CDKN2A/CDKN2B, and HDAC9 polymorphisms and small vessel ischemic strokeActa Neurologica Scandinavica.  137:133-141. 2018
2018 An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohortJournal of Lipid Research.  59:722-729. 2018
2018 Knowledge, attitudes and practices related to stroke in Ghana and Nigeria: A SIREN call to action.PLoS One.  13:e0206548. 2018
2017 Numtogenesis as a mechanism for development of cancerSeminars in Cancer Biology.  47:101-109. 2017
2017 Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunitiesJournal of the Neurological Sciences.  382:18-28. 2017
2017 Post-Deepwater Horizon Oil Spill Exposure Patterns among Children in Mobile County, AlabamaJournal of Occupational and Environmental Medicine.  59:993-999. 2017
2017 An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet NetworkPharmacogenomics.  18:1333-1341. 2017
2017 Interleukin–6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African MenJournal of the Neurological Sciences.  379:229-235. 2017
2017 Exploring Overlaps Between the Genomic and Environmental Determinants of LVH and Stroke: A Multicenter Study in West AfricaGlobal Heart.  12:107-113.e5. 2017
2017 Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) 2017
2017 Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection FractionJournal of Cardiovascular Translational Research.  10:275-284. 2017
2017 Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among AfricansGlobal Heart.  12:99-105. 2017
2017 Stroke in Indigenous Africans, African Americans, and European Americans: Interplay of Racial and Geographic FactorsStroke.  48:1169-1175. 2017
2017 Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma 2017
2017 Biomarkers associated with bronchopulmonary dysplasia/mortality in premature infantsPediatric Research.  81:519-525. 2017
2017 CPT1A methylation is associated with plasma adiponectin 2017
2017 Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies. 2017
2016 Polymorphisms in stearoyl coa desaturase and sterol regulatory element binding protein interact with N-3 polyunsaturated fatty acid intake to modify associations with anthropometric variables and metabolic phenotypes in Yup’ik peopleMolecular Nutrition and Food Research.  60:2642-2653. 2016
2016 Heritable DNA methylation in CD4+ Cells among complex families displays genetic and non-genetic effectsPLoS One.  11. 2016
2016 The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT studyJournal of Human Hypertension.  30:549-554. 2016
2016 Linkage and association analysis of circulating vitamin D and parathyroid hormone identifies novel loci in Alaska native Yup’ik people 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Training in metabolomics research. II. Processing and statistical analysis of metabolomics data, metabolite identification, pathway analysis, applications of metabolomics and its futureJournal of Mass Spectrometry.  51:535-548. 2016
2016 Neurogenomics in Africa: Perspectives, progress, possibilities and prioritiesJournal of the Neurological Sciences.  366:213-223. 2016
2016 Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  461-475. 2016
2016 Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics dataJournal of Mass Spectrometry.  51:ii-iii. 2016
2016 EM adaptive LASSO-a multilocus modeling strategy for detecting SNPs associated with zero-inflated count phenotypesFrontiers in Genetics.  7. 2016
2016 Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: A meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortiumAmerican Journal of Clinical Nutrition.  103:567-578. 2016
2016 Association of DNA methylation at CPT1A locus with metabolic syndrome in the genetics of lipid lowering drugs and diet network (GOLDN) studyPLoS One.  11. 2016
2016 Estimation of cell-type composition including T and B cell subtypes for whole blood methylation microarray dataFrontiers in Genetics.  7. 2016
2016 Genetics, diet, and season are associated with serum 25-hydroxycholecalciferol concentration in a Yup'ik study population from southwestern Alaska 2016
2016 Multilingual validation of the questionnaire for verifying stroke-free status in West AfricaStroke.  47:167-172. 2016
2015 Endothelin-1 pathway polymorphisms and outcomes in pulmonary arterial hypertensionAmerican Journal of Respiratory and Critical Care Medicine.  192:1345-1354. 2015
2015 Mitochondrial DNA polymerase POLG1 disease mutations and germline variants promote tumorigenic propertiesPLoS One.  10. 2015
2015 Phenotyping Stroke in Sub-Saharan Africa: Stroke Investigative Research and Education Network (SIREN) Phenomics ProtocolNeuroepidemiology.  45:73-82. 2015
2015 Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) 2015
2015 A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet NetworkPharmacogenetics and Genomics.  25:511-514. 2015
2015 A Sequence Kernel Association Test for Dichotomous Traits in Family Samples under a Generalized Linear Mixed Model 2015
2015 Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumferenceObesity.  23:1493-1501. 2015
2015 Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCXPharmacogenetics and Genomics.  25:343-353. 2015
2015 Linkage and association analysis of obesity traits reveals novel loci and interactions with dietary n-3 fatty acids in an Alaska Native (Yup'ik) population 2015
2015 Stroke genomics in people of African ancestry: Charting new paths 2015
2015 The burden of stroke in Africa: A glance at the present and a glimpse into the future 2015
2015 Associating multivariate quantitative phenotypes with genetic variants in family samples with a novel kernel machine regression method 2015
2015 Integrated genomic and BMI analysis for type 2 diabetes risk assessmentFrontiers in Genetics.  5. 2015
2015 Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN studyFrontiers in Genetics.  6. 2015
2015 PCSK9 variation and association with blood pressure in African Americans: Preliminary findings from the HyperGEN and REGARDS studiesFrontiers in Genetics.  6. 2015
2014 Longevity and plasticity of CFTR provide an argument for noncanonical SNP organization in hominid DNAPLoS One.  9. 2014
2014 Genetic risk scores associated with baseline lipoprotein subfraction concentrations do not associate with their responses to fenofibrateBiology.  3:536-550. 2014
2014 Epigenome-wide association study of fasting blood lipids in the genetics of lipid-lowering drugs and diet network studyCirculation.  130:565-572. 2014
2014 Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) studyPLoS One.  9. 2014
2014 Epigenome-wide association study of fasting measures of glucose, insulin, and homa-ir in the genetics of lipid lowering drugs and diet network studyDiabetes.  63:801-807. 2014
2014 DNA methylation patterns are associated with n-3 fatty acid intake in Yup'ik people 2014
2014 Genetic association analysis of 30 genes related to obesity in a European American populationInternational Journal of Obesity.  38:724-729. 2014
2014 Kernel-machine testing coupled with a rank-truncation method for genetic pathway analysisGenetic Epidemiology.  38:447-456. 2014
2014 Methylation at CPT1A locus is associated with lipoprotein subfraction profi lesJournal of Lipid Research.  55:1324-1330. 2014
2014 The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study.Frontiers in Pharmacology.  5:210. 2014
2013 Editorial: Ethnic-specific genetic analyses in rheumatoid arthritis: Incremental gains but valuable contributions to the big pictureArthritis and Rheumatism.  65:3014-3016. 2013
2013 Evidence for novel genetic loci associated with metabolic traits in Yup'ik peopleAmerican Journal of Human Biology.  25:673-680. 2013
2013 Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variantsGenetic Epidemiology.  37:560-570. 2013
2013 Obesity polymorphisms identified in genome-wide association studies interact with n-3 polyunsaturated fatty acid intake and modify the genetic association with adiposity phenotypes in Yup'ik people 2013
2013 Risk-stratified imputation in survival analysisClinical Trials.  10:530-539. 2013
2013 The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: The GOLDN study 2013
2013 A431: Epigenetics of Fasting Insulin and Glucose ConcentrationsDiabetes.  62:A431-A431. 2013
2013 Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicityHuman Genetics.  132:405-413. 2013
2013 Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network 2013
2013 The association between LRP-1 variants and chylomicron uptake after a high fat meal 2013
2012 Copy number variations associated with obesity-related traits in African Americans: A joint analysis between GENOA and HyperGENObesity.  20:2431-2437. 2012
2012 The utility of mitochondrial and Y chromosome phylogenetic data to improve correction for population stratificationFrontiers in Genetics.  3. 2012
2012 Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophyFrontiers in Genetics.  3. 2012
2012 Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to FenofibratePLoS One.  7. 2012
2012 Haplotype-Based Methods for Detecting Uncommon Causal Variants With Common SNPsGenetic Epidemiology.  36:572-582. 2012
2012 Genotype Imputation for African Americans Using Data From HapMap Phase II Versus 1000 Genomes ProjectsGenetic Epidemiology.  36:508-516. 2012
2012 Similarity-Based Multimarker Association Tests for Continuous TraitsAnnals of Human Genetics.  76:246-260. 2012
2012 The impact of errors in copy number variation detection algorithms on association resultsPLoS One.  7. 2012
2012 Association between family risk of stroke and myocardial infarction with prevalent risk factors and coexisting diseasesStroke.  43:974-979. 2012
2012 Age-related somatic structural changes in the nuclear genome of human blood cellsAmerican Journal of Human Genetics.  90:217-228. 2012
2012 Preliminary evidence for an association between LRP-1 genotype and body mass index in humansPLoS One.  7. 2012
2012 Response to the Letter 'Efficiency loss due to varying cluster sizes in cluster randomized trials and how to compensate for it: Comment on You et al. (2011)' by van Breukelen and CandelClinical Trials.  9:126-127. 2012
2012 A simple distribution-free algorithm for generating simulated high-dimensional correlated data with an autoregressive structure 2012
2012 Genetic polymorphisms in carnitine palmitoyltransferase 1A gene are associated with variation in body composition and fasting lipid traits in Yup'ik EskimosJournal of Lipid Research.  53:175-184. 2012
2012 Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibratePharmacogenetics and Genomics.  22:750-757. 2012
2012 Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network StudyPharmacogenetics and Genomics.  22:367-372. 2012
2011 A clustering analysis of lipoprotein diameters in the metabolic syndromeLipids in Health and Disease.  10. 2011
2011 Association of allelic variation in genes mediating aspects of energy homeostasis with weight gain during administration of antipsychotic drugs (CATIE study)Frontiers in Genetics.  2. 2011
2011 Characterization of autosomal copy-number variation in African Americans: The HyperGEN StudyEuropean Journal of Human Genetics.  19:1271-1275. 2011
2011 Dietary carbohydrate modifies the inverse association between saturated fat intake and cholesterol on very low-density lipoproteinsLipid Insights.  4:7-15. 2011
2011 Grand challenges in statistical genetics/genomics methodologyFrontiers in Genetics.  2. 2011
2011 Imputation of incident events in longitudinal cohort studiesAmerican Journal of Epidemiology.  174:718-726. 2011
2011 Genome-wide detection of allele specific copy number variation associated with insulin resistance in african americans from the hyperGEN studyPLoS One.  6. 2011
2011 Lipoprotein Lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetSLipids in Health and Disease.  10. 2011
2011 Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive familiesCirculation Research.  108:279-283. 2011
2011 Relative efficiency and sample size for cluster randomized trials with variable cluster sizesClinical Trials.  8:27-36. 2011
2011 Response to letter regarding article, "Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the GOLDN study"Circulation: Cardiovascular Genetics.  4. 2011
2011 Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: The HyperGEN studyBMC Medical Genomics.  4. 2011
2011 A Method to Assess Linkage Disequilibrium between CNVs and SNPs Inside Copy Number Variable Regions.Frontiers in Genetics.  2:17. 2011
2011 Accurate and flexible power calculations on the spot: Applications to genomic researchStatistics and its Interface.  4:353-358. 2011
2011 Association of a common LAMA5 variant with anthropometric and metabolic traits in an Italian cohort of healthy elderly subjectsExperimental Gerontology.  46:60-64. 2011
2011 Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected menPharmacogenetics and Genomics.  21:798-807. 2011
2010 Apolipoprotein e polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the genetics of lipid lowering and diet network (GOLDN) studyCirculation: Cardiovascular Genetics.  3:462-467. 2010
2010 Mixed linear model approach adapted for genome-wide association studiesNature Genetics.  42:355-360. 2010
2010 Within-Cluster Resampling for Analysis of Family Data: Ready for Prime-Time?Statistics and its Interface.  3:169-176. 2010
2010 Association test of multiallelic gene copy numbers in family triosGenetic Epidemiology.  34:2-6. 2010
2010 Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT StudyJournal of Hypertension.  28:2076-2083. 2010
2009 The FCRL3 -169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cellsArthritis and Rheumatism.  60:3510-3512. 2009
2009 A new estimate of family disease history providing improved prediction of disease risksStatistics in Medicine.  28:1269-1283. 2009
2009 Database mining for selection of SNP markers useful in admixture mappingBioData Mining.  2. 2009
2009 Multiple imputation to correct for measurement error in admixture estimates in genetic structured association testing 2009
2009 The use of plasmodes as a supplement to simulations: A simple example evaluating individual admixture estimation methodologiesComputational Statistics and Data Analysis.  53:1755-1766. 2009
2009 An african ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in african americansPLoS Genetics.  5. 2009
2009 Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations 2009
2009 Retraction: an African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.PLoS Genetics.  5. 2009
2008 Phenotypically Concordant and Discordant Monozygotic Twins Display Different DNA Copy-Number-Variation ProfilesAmerican Journal of Human Genetics.  82:763-771. 2008
2008 Review and evaluation of methods correcting for population stratification with a focus on underlying statistical principles 2008
2008 Statistical issues in the analysis of DNA Copy Number Variations.International Journal of Computational Biology and Drug Design.  1:368-395. 2008
2007 Powerful designs for genetic association studies that consider twins and sibling pairs with discordant genotypesGenetic Epidemiology.  31:789-796. 2007
2007 Effects of chronic stress and interleukin-10 gene polymorphisms on antibody response to tetanus vaccine in family caregivers of patients with Alzheimer's diseasePsychosomatic Medicine.  69:551-559. 2007
2007 Problems with genome-wide association studies [2]Science.  316:1840-1841. 2007
2007 Detection of gene x gene interactions in genome-wide association studies of human population data 2007
2006 Regional admixture mapping and structured association testing: Conceptual unification and an extensible general linear modelPLoS Genetics.  2:1254-1264. 2006
2006 Racial or ethnic differences in allele frequencies of sinqle-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritisAnnals of the Rheumatic Diseases.  65:1213-1218. 2006
2006 Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model.PLoS Genetics.  2. 2006
2006 Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adultsInternational Journal of Obesity.  30:233-237. 2006
2005 COGA phenotypes and linkages on chromosome 2BMC Genomic Data.  6. 2005
2005 A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26Annals of Neurology.  58:449-458. 2005
2005 Is GAD2 on chromosome 10p12 a potential candidate gene for morbid obesity?Nutrition Reviews.  63:315-319. 2005
2005 New joint covariance- and marginal-based tests for association and linkage for quantitative traits for random and non-random samplingGenetic Epidemiology.  28:48-57. 2005
2004 The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanerceptArthritis and Rheumatism.  50:2750-2756. 2004
2004 Genome scans for human nutritional traits: what have we learned?Nutrition.  20:9-13. 2004
2003 Do allelic variants of SLC6A14 predispose to obesity?Journal of Clinical Investigation.  112:1633-1636. 2003
2003 Early rheumatoid arthritis in African-Americans: The CLEAR registryClinical and Experimental Rheumatology.  21. 2003
2003 X-linked extension of the revised Haseman-Elston algorithm for linkage analysis in sib pairs 2003
2003 Heritability analysis of cytokines as intermediate phenotypes of tuberculosisJournal of Infectious Diseases.  187:1679-1685. 2003
2003 Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticismAmerican Journal of Human Genetics.  72:879-890. 2003
2003 A genome-wide linkage analysis investigating the determinants of blood pressure in whites and African Americans.American Journal of Hypertension.  16:151-153. 2003
2003 Early rheumatoid arthritis in African-Americans: the CLEAR Registry.Clinical and Experimental Rheumatology.  21:S138-S145. 2003
2003 Familial correlations and heritability of maxillary midline diastemaAmerican Journal of Orthodontics and Dentofacial Orthopedics.  123:35-39. 2003
2003 Structural equation model-based genome scan for the metabolic syndrome.BMC Genomic Data.  4 Suppl 1. 2003
2002 Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations.American Journal of Human Genetics.  70:1172-1182. 2002
1998 Restrictions on components of variance for epistatic modelsTheoretical Population Biology.  54:161-174. 1998
1997 Linkage of multilocus components of variance to polymorphic markers.Annals of Human Genetics.  61:253-261. 1997
1996 DNA sequences of Alu elements indicate a recent replacement of the human autosomal genetic complement 1996
Integration of Multi-Layer Omic Data for Prediction of Disease Risk

Book

Year Title Altmetric
2008 Definition of Phenotype.  Ed. 60.  2008

Chapter

Year Title Altmetric
2018 Multifactorial inheritance and complex diseases.  323-358. 2018
2014 Multifactorial Inheritance and Complex Diseases 2014
2013 Multifactorial Inheritance and Complex Diseases.  1-15. 2013
2011 Gene-environment Interactions: Gene-environment interactions in human traits 2011
2011 Gene-Environment Interactions in Human Traits.  855-862. 2011
2009 Population genetics.  163-180. 2009
2007 Overview of genetic studies in polygenic obesity and methodological challenges.  229-246. 2007

Principal Investigator On

  • Characterization and Genetics of Kl toxicity in iPSC-Derived Cardiomyocytes  awarded by Medical College of Wisconsin
  • Epigenetic Determinants and Mechanisms Influencing Genital Chlamydia Trachomatis Reinfection in African American Women  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Epigenome Modification By A Dietary Pattern Rich In Polyunsaturated Fatty Acids  awarded by Oregon Health & Science University
  • Epigenome Modification by a Dietary Pattern Rich in Polyunsaturated Fatty Acids  awarded by University of Alaska Fairbanks
  • Epigenome Modification by a Dietary Pattern Rich in Polyunsaturated Fatty Acids  awarded by University of Alaska Fairbanks
  • Epigenome Modification by a Dietary Pattern Rich in Polyunsaturated Fatty Acids (R01DK112358)  awarded by Oregon Health & Science University
  • Genetics of Obesity in Yup'ik Eskimos  awarded by University of Alaska Fairbanks
  • Program Project in the Genetics of SLE - Core 1 (Genetic Epidemiology & Biostatisics Core)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Short Course on Next-Generation Sequencing: Technology and Statistical Methods  awarded by NIH - OFFICE OF HUMAN GENOME RESEARCH
  • Short Course on Next-Generation Sequencing: Technology and Statistical Methods  awarded by National Human Genome Research Institute/NIH/DHHS
  • Short Course on Statistical Genetics & Genomics  awarded by National Institute of General Medical Sciences/NIH/DHHS
  • Stroke Investigative Research & Educational Network  awarded by UNIVERSITY OF IBADAN
  • The Impact of Enculturation on the Epigenetic Relationship between Chronic Stress and Hypertension in Yup'ik Alaska Native People  awarded by Oregon Health & Science University
  • UAB Biostatistics Pre-Doctoral Training Program  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • UAB Cardiovascular Disease Predoctoral Training Program in Biostatistics and Epidemiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • UAB Statistical Genetics Post-Doctoral Training Program  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • UAB Statistical Genetics Post-Doctoral Training Program  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Investigator On

  • A Genome-Wide Methylation Study of Epigenetic Contributions to Multiple Myeloma  awarded by National Cancer Institute/NIH/DHHS
  • A Genome-Wide Methylation Study of Multiple Myeloma  awarded by HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY
  • A High-Resolution Integrative-Omic Analysis of Cardiorenal Traits in African Americans  awarded by American Heart Association
  • Association of Genetic and Autoantibody Signatures with SLE Clinical Course  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • COPD Cachexia: Deciphering the Impact of Antioxidants, Iron and Mitochondrial Function Using 'Omics Approaches  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • COPD Cachexia: Deciphering the Impact of Antioxidants, Iron and Mitochondrial Function Using 'Omics Approaches  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Cardiorenal Genomics for Risk Prediction in African Descent Populations  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Characterization of the Lupus Nephritis microRNAome  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Early Life Prevention of Breast Cancer with Combined Epigenetic Botanicals  awarded by National Cancer Institute/NIH/DHHS
  • Early Life Stress, DNA Methylation, and Health Disparities Across Ages  awarded by NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES/NIH/DHHS
  • Epigenetic Biomarkers of Preeclampsia Risk Among Mothers with Chronic Hypertension  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Epigenetic Determinants of Left Ventricular Structure and Function in Hypertensive African Americans  awarded by American Heart Association
  • Epigenetic Determinants of Left Ventricular Structure and Function in Hypertensive African Americans  awarded by University of Kentucky
  • Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Epigenetic Regulation of Lipids in Response to Dietary Fat and Fenofibrate  awarded by University of Kentucky
  • Epigenomics of Cardiometabolic Diseases in Mexican Americans  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genetic Architecture of Rheumatoid Arthritis in African-Americans  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Genetic Epidemiology of GERD in COPD  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genetic Underpinnings of Cardiorenal risk in Africans and African Americans  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genome-Wide Association Study in African-Americans With Rheumatoid Arthritis  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by University of Kentucky
  • Genomic Background of Blood Pressure Response to Thiazide Diuretic in African Americans  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genomics of Lipidomic Phenotypes in a Postprandial Intervention Dietary Study  awarded by American Heart Association
  • HyperGEN: Genetics of Left Ventricular Hypertrophy  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • HyperGEN: Genetics of Left Ventricular Hypertrophy  awarded by University of Kentucky
  • Hypergen: Genetics of Left Ventricular Hypertrophy  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Immunogenetic Determinants of Chlamydia Reinfection and Chlamydia-Associated Infertility in Women  awarded by National Institute of Child Health and Human Development/NIH/DHHS
  • Integrative -omics Study of Postprandial Lipoprotein Phenotypes  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Mechanisms and Correlates of Immune Protection against Genital Chlamydia in Humans  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Midcareer Mentoring Award for Patient-Oriented Research in Chlamydia Trachomatis Infection  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Molecular Genetic Analysis of Human Obesity  awarded by Columbia University
  • Pharmacometric Approaches to Precision Optimization of Ivacaftor Response in Cystic Fibrosis Patients  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Predictors of Youth-Onset Type 2 Diabetes: UAB Clinical Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Program Project in the Genetics of SLE  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Program Project in the Genetics of SLE - Core 1 (Genetic Epidemiology & Biostatisics Core)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • Race, Natriuretic Peptides and Physiological Perturbations  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Racial Differences in the Natriuretic Peptide Response to Exercise and Beta-blockers  awarded by American Heart Association
  • Statistical Tools for Whole-Genome Prediction of Complex Traits and Disease  awarded by National Institute of General Medical Sciences/NIH/DHHS
  • Stroke Investigative Research & Educational Network (SIREN)  awarded by UNIVERSITY OF IBADAN
  • Training Program in Cardiovascular Pathophysiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • UAB Metabolomics Workshop: From Design to Decision  awarded by National Institute of General Medical Sciences/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research - Admin Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Teaching Activities

  • BST631 - Statistical Theory I (Fall Term 2010)
  • BST631 - Statistical Theory I (Fall Term 2011)
  • BST631 - Statistical Theory I (Fall Term 2012)
  • BST631 - Statistical Theory I (Fall Term 2013)
  • BST631 - Statistical Theory I (Fall Term 2014)
  • BST631 - Statistical Theory I (Fall Term 2015)
  • BST631 - Statistical Theory I (Fall Term 2016)
  • BST631 - Statistical Theory I (Fall Term 2020)
  • BST631 - Statistical Theory I (Fall Term 2021)
  • BST631 - Statistical Theory I (Fall Term 2022)
  • BST632 - Statistical Theory II (Spring Term 2016)
  • BST675 - Intro. to Statistical Genetics (Fall Term 2018)
  • BST676 - Genomic Data Analysis (Spring Term 2019)
  • BST690 - Biostatic Consult and App Prob (Spring Term 2010)
  • BST690 - Biostatistical Consulting (Spring Term 2009)
  • BST698 - Non Thesis Research (Fall Term 2007)
  • BST698 - Non Thesis Research (Fall Term 2013)
  • BST698 - Non Thesis Research (Fall Term 2014)
  • BST698 - Non Thesis Research (Fall Term 2020)
  • BST698 - Non Thesis Research (Fall Term 2022)
  • BST698 - Non Thesis Research (Spring Term 2017)
  • BST698 - Non Thesis Research (Spring Term 2018)
  • BST698 - Non Thesis Research (Summer Term 2010)
  • BST698 - Non Thesis Research (Summer Term 2015)
  • BST698 - Non Thesis Research (Summer Term 2017)
  • BST775 - Stat Meth Genetic Analysis I (Fall Term 2008)
  • BST776 - Stat Meth Genetic Analysis II (Fall Term 2009)
  • BST795 - Advanced Special Topics (Fall Term 2017)
  • BST795 - Advanced Special Topics (Spring Term 2021)
  • BST798 - Non-Dissertation Research (Fall Term 2010)
  • BST798 - Non-Dissertation Research (Fall Term 2013)
  • BST798 - Non-Dissertation Research (Fall Term 2014)
  • BST798 - Non-Dissertation Research (Fall Term 2016)
  • BST798 - Non-Dissertation Research (Fall Term 2017)
  • BST798 - Non-Dissertation Research (Fall Term 2018)
  • BST798 - Non-Dissertation Research (Fall Term 2019)
  • BST798 - Non-Dissertation Research (Spring Term 2014)
  • BST798 - Non-Dissertation Research (Spring Term 2017)
  • BST798 - Non-Dissertation Research (Spring Term 2018)
  • BST798 - Non-Dissertation Research (Spring Term 2019)
  • BST798 - Non-Dissertation Research (Summer Term 2016)
  • BST798 - Non-Dissertation Research (Summer Term 2017)
  • BST798 - Non-Dissertation Research (Summer Term 2018)
  • BST798 - Non-Dissertation Research (Summer Term 2019)
  • BST798 - Non-Dissertation Research (Summer Term 2022)
  • BST799 - Dissertation Research (Fall Term 2009)
  • BST799 - Dissertation Research (Fall Term 2010)
  • BST799 - Dissertation Research (Fall Term 2015)
  • BST799 - Dissertation Research (Fall Term 2017)
  • BST799 - Dissertation Research (Fall Term 2020)
  • BST799 - Dissertation Research (Fall Term 2021)
  • BST799 - Dissertation Research (Spring Term 2009)
  • BST799 - Dissertation Research (Spring Term 2010)
  • BST799 - Dissertation Research (Spring Term 2011)
  • BST799 - Dissertation Research (Spring Term 2015)
  • BST799 - Dissertation Research (Spring Term 2018)
  • BST799 - Dissertation Research (Spring Term 2020)
  • BST799 - Dissertation Research (Spring Term 2021)
  • BST799 - Dissertation Research (Summer Term 2010)
  • BST799 - Dissertation Research (Summer Term 2011)
  • BST799 - Dissertation Research (Summer Term 2015)
  • BST799 - Dissertation Research (Summer Term 2018)
  • BST799 - Dissertation Research (Summer Term 2020)
  • BST799 - Dissertation Research (Summer Term 2021)
  • EPI706 - EPI of CVC (Fall Term 2019)
  • GBS787 - Special Topics (Fall Term 2015)
  • Education And Training

  • Doctor of Philosophy in Mathematics, University of Notre Dame 1986
  • Full Name

  • Hemant Tiwari