Selected Publications

Academic Article

Year Title Altmetric
2022 CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell AgingAmerican Journal of Respiratory and Critical Care Medicine.  206:459-475. 2022
2022 DOCK-t(w)o Pleural FibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  66:117-119. 2022
2021 AICAR Decreases Acute Lung injury by Phosphorylating AMPK and Upregulating Heme Oxygenase-1European Respiratory Journal.  58. 2021
2021 Lung myofibroblasts promote macrophage profibrotic activity through lactate-induced histone lactylationAmerican Journal of Respiratory Cell and Molecular Biology.  64:115-125. 2021
2020 ATF4 mediates mitochondrial unfolded protein response in alveolar epithelial cellsAmerican Journal of Respiratory Cell and Molecular Biology.  63:478-489. 2020
2020 Monocyte-derived alveolar macrophage apolipoprotein E participates in pulmonary fibrosis resolutionJCI Insight.  5. 2020
2019 Inhibition of glutaminase 1 attenuates experimental pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  61:492-500. 2019
2019 Long noncoding RNA Malat1 regulates differential activation of macrophages and response to lung injuryJCI Insight.  4. 2019
2019 Impairment of fatty acid oxidation in alveolar epithelial cells mediates acute lung injuryAmerican Journal of Respiratory Cell and Molecular Biology.  60:167-178. 2019
2018 IFN regulatory factor 2 inhibits expression of glycolytic genes and lipopolysaccharide-Induced proinflammatory responses in macrophagesJournal of Immunology.  200:3218-3230. 2018
2018 Glutaminolysis promotes collagen translation and stability via a-ketoglutarate-mediated mTOR activation and proline hydroxylationAmerican Journal of Respiratory Cell and Molecular Biology.  58:378-390. 2018
2017 Metabolic characterization and RNA profiling reveal glycolytic dependence of profibrotic phenotype of alveolar macrophages in lung fibrosis 2017
2017 Fish miR-146a promotes Singapore grouper iridovirus infection by regulating cell apoptosis and NF-κB activationJournal of General Virology.  98:1489-1499. 2017
2017 miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions 2017
2017 MIR-34a inhibits lung fibrosis by inducing lung fibroblast senescenceAmerican Journal of Respiratory Cell and Molecular Biology.  56:168-178. 2017
2016 MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiationAmerican Journal of Respiratory Cell and Molecular Biology.  54:843-852. 2016
2015 Glycolytic reprogramming in myofibroblast differentiation and lung fibrosisAmerican Journal of Respiratory and Critical Care Medicine.  192:1462-1474. 2015
2015 Comprehensive identification and profiling of host miRNAs in response to Singapore grouper iridovirus (SGIV) infection in grouper (Epinephelus coioides)Developmental and Comparative Immunology.  52:226-235. 2015
2015 The code of non-coding RNAs in lung fibrosisCellular and Molecular Life Sciences.  72:3507-3519. 2015
2015 Singapore grouper iridovirus (SGIV) encoded SGIV-miR-13 attenuates viral infection via modulating major capsid protein expressionVirus Research.  205:45-53. 2015
2015 Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolismJournal of Immunology.  194:6082-6089. 2015
2015 The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophagesJournal of Biological Chemistry.  290:46-55. 2015
2014 MiR-27a regulates inflammatory response of macrophages by targeting IL-10Journal of Immunology.  193:327-334. 2014
2014 Singapore grouper iridovirus-encoded semaphorin homologue (SGIV-sema) contributes to viral replication, cytoskeleton reorganization and inhibition of cellular immune responsesJournal of General Virology.  95:1144-1155. 2014
2014 The human long noncoding RNA lnc-IL7R regulates the inflammatory responseEuropean Journal of Immunology.  44:2085-2095. 2014
2013 MiR-125a-5p regulates differential activation of macrophages and inflammationJournal of Biological Chemistry.  288:35428-35436. 2013
2013 MiR-homoHSV of Singapore Grouper Iridovirus (SGIV) inhibits expression of the SGIV pro-apoptotic factor LITAF and attenuates cell deathPLoS One.  8. 2013
2013 An insulin-like growth factor homologue of Singapore grouper iridovirus modulates cell proliferation, apoptosis and enhances viral replicationJournal of General Virology.  94:2759-2770. 2013
2013 MicroRNA let-7c regulates macrophage polarizationJournal of Immunology.  190:6542-6549. 2013
2013 MiR-145 regulates myofibroblast differentiation and lung fibrosis 2013
2013 Erratum: miR-31 is a negative regulator of pulmonary fibrosis (FASEB Journal (2012) 26:9 (3790-3799)) 2013
2012 Functional genomic studies on an immune- and antiviral-related gene of MyD88 in orange-spotted grouper, Epinephelus coioidesChinese Science Bulletin.  57:3277-3287. 2012
2012 miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis 2012
2012 Identification of TLT2 as an engulfment receptor for apoptotic cellsJournal of Immunology.  188:6381-6388. 2012
2012 Extracellular histones inhibit efferocytosisMolecular Medicine.  18:825-833. 2012
2012 MiR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling 2012
2011 Transcriptome analysis of orange-spotted grouper (Epinephelus coioides) spleen in response to Singapore grouper iridovirusBMC Genomics.  12. 2011
2011 Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling 2011
2011 Identification and functional characterization of an interferon regulatory factor 7-like (IRF7-like) gene from orange-spotted grouper, Epinephelus coioidesDevelopmental and Comparative Immunology.  35:672-684. 2011
2011 Identification of a novel marine fish virus, Singapore grouper iridovirus-encoded microRNAs expressed in grouper cells by Solexa sequencingPLoS One.  6. 2011
2011 A new leukocyte cell-derived chemotaxin-2 from marine fish grouper, Epinephelus coioides: Molecular cloning and expression analysisFish and Shellfish Immunology.  31:600-605. 2011
2011 Cloning, characterization, and expression analysis of orange-spotted grouper (Epinephelus coioides) ILF2 gene (EcILF2)Fish and Shellfish Immunology.  30:378-388. 2011
2011 Molecular cloning and characterization of two novel hepcidins from orange-spotted grouper, Epinephelus coioidesFish and Shellfish Immunology.  30:559-568. 2011
2010 Differential profiles of gene expression in grouper Epinephelus coioides, infected with Singapore grouper iridovirus, revealed by suppression subtractive hybridization and DNA microarrayJournal of Fish Biology.  77:341-360. 2010
2010 Molecular cloning, characterization and expression analysis of a C-type lectin (Ec-CTL) in orange-spotted grouper, Epinephelus coioidesFish and Shellfish Immunology.  28:178-186. 2010
2009 Complete sequence determination of a novel reptile iridovirus isolated from soft-shelled turtle and evolutionary analysis of IridoviridaeBMC Genomics.  10. 2009
2008 Rapid and sensitive detection of Singapore grouper iridovirus by loop-mediated isothermal amplificationJournal of Applied Microbiology.  105:389-397. 2008


Year Title Altmetric
2015 How noncoding RNAs contribute to macrophage polarization.  59-84. 2015

Education And Training

  • Doctor of Philosophy in Molecular Biology, Sun Yat-Sen University 2011
  • Full Name

  • Huachun Cui