• Dr. Kennedy is certified by the American Board of Colon and Rectal Surgery and by the American Board of Surgery. In addition, he is a Fellow of the American College of Surgeons and a Fellow of the American Society of Colon and Rectal Surgery. Kennedy’s main interest is in laparoscopic approaches to complex colorectal disease. He has experience with all advanced laparoscopic and minimally invasive approaches including single-incision laparoscopy and robotic surgery. His clinical areas of expertise include colon cancer, rectal cancer, inflammatory bowel disease, benign conditions of colon, rectum, and anus, and endoscopic treatment of colonic disease.

    Dr. Kennedy was born and raised in Montana and is a graduate of the University of Washington School of Medicine in Seattle. He earned his doctorate in cancer biology at the University of Wisconsin School of Medicine and Public Health, where he also completed his general surgery residency in 2006. Dr. Kennedy then completed his colon and rectal surgery fellowship at the Mayo Clinic in Rochester, Minn., in 2007.

    Dr. Kennedy’s research efforts are focused on chemoprevention of colon and rectal cancer. His funded laboratory uses genetic models to better understand how chemicals prevent tumor formation and what genetic pathways are responsible for their effects. The ultimate goal is to identify targeted agents that are better tolerated by patients in hopes of preventing colon and rectal cancer.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Multidisciplinary clinics for colorectal cancer may not provide more efficient coordination of care 2022
    2021 NIH Funding of Researchers in Surgery: Decreased Career Development Awards Over TimeJournal of Surgical Research.  266:6-12. 2021
    2021 Visual teaching aids improve patient understanding and reduce anxiety prior to a colectomy 2021
    2021 The impact of an enhanced recovery program (ERP) on the costs of colorectal surgery 2021
    2021 Preoperative Tamsulosin to Prevent Postoperative Urinary Retention: A Randomized Controlled TrialJournal of Surgical Research.  262:130-139. 2021
    2021 Racial disparities exist in surgical outcomes for patients with inflammatory bowel disease 2021
    2021 Early Elective Surgery After Colon Cancer Diagnosis has Higher Risk of Readmission and DeathAnnals of Surgery.  273:188-194. 2021
    2020 Looking Ahead: the SSAT Strategic Plan Version 2.0 for the Next DecadeJournal of Gastrointestinal Surgery.  24:2441-2446. 2020
    2020 Low Health Literacy Exists in the Inflammatory Bowel Disease (IBD) Population and Is Disproportionately Prevalent in Older African AmericansCrohn's & Colitis 360.  2:1-7. 2020
    2020 Proximal diversion after colectomy: The debate continues 2020
    2020 EDITORIAL: From the Editors of AJS 2020
    2020 Curcumin Conjugates of Non-steroidal Anti-Inflammatory Drugs: Synthesis, Structures, Anti-proliferative Assays, Computational Docking, and Inflammatory ResponseChemistryOpen.  9:822-834. 2020
    2020 Strategies to prevent burnout: Are grit and optimism the answer? 2020
    2020 Early removal of catheters in an Enhanced Recovery Pathway (ERP) with intrathecal opioid injection does not affect postoperative urinary outcomes 2020
    2020 Postoperative Complications After Colorectal Surgery: Where Are We in the Era of Enhanced Recovery?Current Colorectal Cancer Reports.  22. 2020
    2020 Noninvasive Detection of Colorectal Carcinomas Using Serum Protein BiomarkersJournal of Surgical Research.  246:160-169. 2020
    2020 The association of enhanced recovery pathway and acute kidney injury in patients undergoing colorectal surgeryDiseases of the Colon and Rectum.  233-241. 2020
    2019 Panitumumab-IRDye800CW for Fluorescence-Guided Surgical Resection of Colorectal CancerJournal of Surgical Research.  239:44-51. 2019
    2019 Deuterated Curcuminoids: Synthesis, Structures, Computational/Docking and Comparative Cell Viability Assays against Colorectal Cancer 2019
    2019 SSAT State-of-the-Art Conference: Advances in the Management of Rectal CancerJournal of Gastrointestinal Surgery.  23:433-442. 2019
    2018 The role of mechanical bowel preparation and oral antibiotics for left-sided laparoscopic and open elective restorative colorectal surgery with and without faecal diversion 2018
    2018 Synthesis, Computational Docking Study, and Biological Evaluation of a Library of Heterocyclic Curcuminoids with Remarkable Antitumor Activity. 2018
    2018 Achieving health equity in surgery through enhanced recovery after surgery (ERAS): The elimination of racial disparities in post-operative length-of-stay is sustained long-termClinical nutrition ESPEN.  25:178-179. 2018
    2018 Racial Disparities After Stoma Construction Exist in Time to Closure After 1 Year but Not in Overall Stoma Reversal RatesJournal of Gastrointestinal Surgery.  22:250-258. 2018
    2018 A tertiary care hospital's 10 years' experience with rectal ultrasound in early rectal cancer.Endoscopic Ultrasound.  7:191-195. 2018
    2017 Enhanced Recovery After Surgery (ERAS) Eliminates Racial Disparities in Postoperative Length of Stay After Colorectal SurgeryAnnals of Surgery2017
    2017 The aryl hydrocarbon receptor as an antitumor target of synthetic curcuminoids in colorectal cancerJournal of Surgical Research.  213:16-24. 2017
    2017 The effect of perioperative fluid management on postoperative ileus in rectal cancer patientsSurgery.  161:1628-1632. 2017
    2017 Preoperative blood transfusion is a predictor of worse short-term postoperative outcomes after colectomySurgery.  161:1067-1075. 2017
    2017 Value of MDCT and Clinical and Laboratory Data for Predicting the Need for Surgical Intervention in Suspected Small-Bowel Obstruction.American Journal of Roentgenology.  208:785-793. 2017
    2017 Abdominal Multidetector Computed Tomography for Suspected Small-Bowel Obstruction: Multireader Study Comparing Radiologist Performance for Predicting Surgical Outcomes. 2017
    2017 Incorporation of Leadership Rounds in CAUTI Prevention EffortsJournal of Nursing Care Quality.  32:318-323. 2017
    2016 Multiple postoperative complications: Making sense of the trajectoriesSurgery.  160:1666-1674. 2016
    2016 Hot Topics in Colorectal SurgeryClinics in Colon and Rectal Surgery.  29:183. 2016
    2016 Postoperative Complications: Looking Forward to a Safer FutureClinics in Colon and Rectal Surgery.  29:246-252. 2016
    2016 Preoperative urinary tract infection increases postoperative morbidityJournal of Surgical Research.  205:213-220. 2016
    2016 Strategies to Reduce Postoperative Urinary Tract InfectionsAdvances in Surgery.  50:79-91. 2016
    2016 The aryl hydrocarbon receptor is a repressor of inflammation-associated colorectal tumorigenesis in mouseAnnals of Surgery.  264:429-435. 2016
    2016 Postacute care after major abdominal surgery in elderly patients intersection of age, functional status, and postoperative complicationsJAMA Surgery.  151:759-766. 2016
    2016 Indole-3-carbinol induces tumor cell death: Function follows formJournal of Surgical Research.  204:47-54. 2016
    2016 National Trends in Short-term Outcomes Following Non-emergent Surgery for Diverticular DiseaseJournal of Gastrointestinal Surgery.  20:1376-1387. 2016
    2016 Short-term outcomes of minimally invasive versus open colectomy for colon cancerJournal of Surgical Research.  204:83-93. 2016
    2016 Independent risk factors for prolonged postoperative ileus developmentJournal of Surgical Research.  201:279-285. 2016
    2016 The log odds of positive elymph nodes stratifies and predicts survival of high-risk individuals among stage III rectal cancer patients 2016
    2016 Intestinal inflammation and the diet: Is food friend or foe?World Journal of Gastrointestinal Surgery.  8:115-123. 2016
    2016 Process improvement in surgeryCurrent Problems in Surgery.  53:62-96. 2016
    2016 Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cellsCancer Letters.  370:91-99. 2016
    2016 Does anastomotic leak contribute to high failure-to-rescue rates?Annals of Surgery.  263:1148-1151. 2016
    2016 Implications of multiple complications on the postoperative recovery of general surgery patientsAnnals of Surgery.  263:1213-1218. 2016
    2016 Modeling the Temporal Evolution of Postoperative ComplicationsProceedings / AMIA ... Annual Symposium. AMIA Symposium.  2016:551-559. 2016
    2016 Urinary tract infection after surgery for colorectal malignancy: Risk factors and complications Presented as a podium presentation at the 2015 Academic Surgical Congress, March 2, 2015 to May 2, 2015, Las Vegas, Nevada. 2016
    2015 Variation reduction to reduce readmission: A figment of imagination or reality of the future?JAMA Surgery.  150:1049-1050. 2015
    2015 Postoperative Ileus—More than Just Prolonged Length of Stay?Journal of Gastrointestinal Surgery.  19:1684-1690. 2015
    2015 Is There a Relationship Between Patient Satisfaction and Favorable Surgical Outcomes?Advances in Surgery.  49:221-233. 2015
    2015 Some important deficiencies in the development, validation, and reporting of a prediction model [2]JAMA Surgery.  150:915-916. 2015
    2015 Nomogram to predict postoperative readmission in patients who undergo general surgeryJAMA Surgery.  150:505-510. 2015
    2015 Patient satisfaction: Does surgical volume matter?Journal of Surgical Research.  196:124-129. 2015
    2015 Development of a list of high-risk operations for patients 65 years and olderJAMA Surgery.  150:325-331. 2015
    2015 Characterizing Readmission in Ulcerative Colitis Patients Undergoing Restorative ProctocolectomyJournal of Gastrointestinal Surgery.  19:564-569. 2015
    2015 Preoperative impairment is associated with a higher postdischarge level of careJournal of Surgical Research.  193:1-6. 2015
    2014 Can patients reliably identify safe, high quality care?Journal of Hospital Administration.  3:150-160. 2014
    2014 Postdischarge complications are an important predictor of postoperative readmissions 2014
    2014 Readmission after delayed diagnosis of surgical site infection: a focus on prevention using the American College of Surgeons National Surgical Quality Improvement Program. 2014
    2014 Carpet lesions detected at CT colonography: Clinical, imaging, and pathologic featuresRadiology.  270:435-443. 2014
    2014 Response.Radiology.  270:632. 2014
    2014 A composite index for predicting readmission following emergency general surgeryJournal of Trauma and Acute Care Surgery.  76:1467-1472. 2014
    2014 Advancing quality measurement to include the patient perspectiveAnnals of Surgery.  260:10-12. 2014
    2014 Catheter-associated urinary tract infection: a successful prevention effort employing a multipronged initiative at an academic medical center.Journal of Nursing Care Quality.  29:141-148. 2014
    2014 Is there a relationship between patient satisfaction and favorable outcomes?Annals of Surgery.  260:592-600. 2014
    2014 Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptorsToxicological Sciences.  140:135-143. 2014
    2014 Multiple complications and short length of stay are associated with postoperative readmissions 2014
    2014 Overview: Getting involved in research as a busy practicing surgeonClinics in Colon and Rectal Surgery.  27:43-47. 2014
    2013 Postoperative complications in patients with rectal cancer are associated with delays in chemotherapy that lead to worse disease-free and overall survivalDiseases of the Colon and Rectum.  56:1339-1348. 2013
    2013 Postoperative complications and implications on patient-centered outcomesJournal of Surgical Research.  181:106-113. 2013
    2013 Predictors of mortality after emergent surgery for acute colonic diverticulitis: Analysis of National Surgical Quality Improvement Project dataJournal of Trauma and Acute Care Surgery.  74:611-616. 2013
    2013 Failure of a constrained acetabular liner without reinforcement ring disruption.American journal of orthopedics (Belle Mead, N.J.).  42:566-568. 2013
    2012 Comparable postoperative morbidity and mortality after laparoscopic and open emergent restorative colectomy: Outcomes from the ACS NSQIPWorld Journal of Surgery.  36:2488-2496. 2012
    2012 SU5416, a VEGF Receptor Inhibitor and Ligand of the AHR, Represents a New Alternative for ImmunomodulationPLoS One.  7. 2012
    2012 Identification of the Ah-receptor structural determinants for ligand preferencesToxicological Sciences.  129:86-97. 2012
    2012 Utility of micro-ribonucleic acid profile for predicting recurrence of rectal cancerJournal of Surgical Research.  177:87-92. 2012
    2012 Assessment of screening colonoscopy competency in colon and rectal surgery fellows: A single institution experienceJournal of Surgical Research.  174. 2012
    2012 Visceral obesity is associated with outcomes of total mesorectal excision for rectal adenocarcinoma 2012
    2012 AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of NotchNature Immunology.  13:144-152. 2012
    2012 Surgical genomics: Using new technology to answer age-old questionsDiseases of the Colon and Rectum.  55:113-114. 2012
    2011 Mortality by stage for right- versus left-sided colon cancer: analysis of surveillance, epidemiology, and end results--Medicare data.Journal of Clinical Oncology.  29:4401-4409. 2011
    2011 Small bowel obstruction following restorative proctocolectomy: affected by a laparoscopic approach?Journal of Surgical Research.  170:202-208. 2011
    2011 Short-term outcomes after laparoscopic-assisted proctectomy for rectal cancer: Results from the ACS NSQIPJournal of the American College of Surgeons.  212:844-854. 2011
    2011 Optimizing surgical care of colon cancer in the older adult populationAnnals of Surgery.  253:508-514. 2011
    2011 Management of stage IV rectal cancer: Palliative optionsWorld Journal of Gastroenterology.  17:835-847. 2011
    2011 Pediatric diabetes registries: When baby steps are not enoughJournal of Diabetes Science and Technology.  5:571-578. 2011
    2010 Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liverToxicological Sciences.  118:554-563. 2010
    2010 Rapamycin inhibits anal carcinogenesis in two preclinical animal modelsCancer Prevention Research.  3:1542-1551. 2010
    2010 The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genesJournal of Biological Chemistry.  285:35599-35605. 2010
    2010 Synthesis of hexa(methyl/phenyl) substituted pyrazolines and thermolysis to hexasubstituted cyclopropanes 2010
    2010 Body mass index does not affect postoperative morbidity and oncologic outcomes of total mesorectal excision for rectal adenocarcinomaAnnals of Surgical Oncology.  17:1606-1613. 2010
    2010 Portal vein thrombus after pediatric proctocolectomy with ileoanal anastomosisJournal of Pediatric Surgery.  45:1026-1029. 2010
    2010 The diagnosis of diverticulitis in outpatients: on what evidence?Journal of Gastrointestinal Surgery.  14:303-308. 2010
    2010 Laparoscopy Improves Short-term Outcomes After Surgery for Diverticular DiseaseGastroenterology.  138. 2010
    2010 Study of stress intensity factor of a cracked steel plate with a single-side CFRP composite patchingJournal of Composites for Construction.  14:791-803. 2010
    2009 Routine evaluation of the distal colon remnant before Hartmann's reversal is not necessary in asymptomatic patientsJournal of Gastrointestinal Surgery.  13:2260-2267. 2009
    2009 Should total number of lymph nodes be used as a quality of care measure for stage III colon cancer?Diseases of the Colon and Rectum.  52:1675-1676. 2009
    2009 Colonoscopic findings and tumor site do not predict bowel obstruction during medical treatment of stage IV colorectal cancer 2009
    2009 Laparoscopy decreases postoperative complication rates after abdominal colectomy: Results from the national surgical quality improvement programAnnals of Surgery.  249:596-601. 2009
    2008 Laparoscopic restorative proctocolectomy with ileal S-pouch.Diseases of the Colon and Rectum.  51:1790-1794. 2008
    2008 Routine ileal intubation during screening colonoscopy: a useful maneuver? 2008
    2007 Radiation colitis and proctitisClinics in Colon and Rectal Surgery.  20:64-72. 2007
    2003 Epstein-Barr virus provides a survival factor to Burkitt's lymphomas. 2003
    2003 EBNA-1, a bifunctional transcriptional activatorMolecular and Cellular Biology.  23:6901-6908. 2003
    2001 Effect of vascular occlusion on radiofrequency ablation of the liver: Results in a porcine modelAmerican Journal of Roentgenology.  176:789-795. 2001
    1999 Metastatic breast cancerSurgical Clinics of North America.  79:1117-1143. 1999


    Year Title Altmetric
    2003 Virus-based vectors for gene expression in mammalian cells: Epstein-Barr virus.  Ed. 38.  2003


    Year Title Altmetric
    2016 Anal fissure.  497-503. 2016
    2016 Cryptoglandular disease.  463-482. 2016
    2016 Hemorrhoids.  505-519. 2016
    2016 Pilonidal disease.  483-496. 2016
    2015 Palliative options in patients with stage 4 rectal cancer.  367-384. 2015
    2010 Cryptoglandular disease.  195-206. 2010
    2010 Hemorrhoids.  217-224. 2010
    2010 Lateral internal sphincterotomy.  189-193. 2010
    2010 Pilonidal operations.  207-215. 2010

    Research Overview

  • colon cancer, rectal cancer, anal cancer, inflammatory bowel disease, benign conditions of colon, rectum and anus, endoscopic treatment of colonic disease, chemoprevention
  • Principal Investigator On

  • PREVENT Cancer Preclinical and Drug Development Program  awarded by NIH - National Institutes of Health/DHHS
  • Preclinical PREVENT Cancer Program: Preclinical Efficacy and Intermediate Endpoint Biomarkers  awarded by NIH - National Institutes of Health/DHHS
  • Private Grant  awarded by AMGEN, INC.^
  • Private Grant  awarded by DAVOL (A.C.R. BARD INC.)
  • Research Training Program in Surgical Oncology  awarded by National Cancer Institute/NIH/DHHS
  • Surgical Oncology Research Training Program  awarded by National Cancer Institute/NIH/DHHS
  • T001 HHSN2610009 (old 000509388-T008) Preclinical PREVENT Cancer Program: Preclinical Efficacy and Intermediate Endpoint Biomarkers - Evaluating Whether a Concurrent Retinoid X Receptor Agonist Can Enhance the Efficacy of HER2-IGFPB2-IGFLR Vaccine in Eliminating Existing Ductal Carcinoma in Situ and Preventing Progression of Invasive Breast Cancer  awarded by NIH - National Institutes of Health/DHHS
  • T002 HHSN261201500036I-75N91018F00011 (Old 000509388-T011) Preclinical Efficacy and Intermediate Endpoint Biomarkers - Further Development of Multi-Antigen Vaccines for the Primary and Secondary Prevention of Bladder Cancer  awarded by NIH - National Institutes of Health/DHHS
  • T005 HHSN26100008 (Old 000509388-T009)TORFP 2018-E03 Prevention of Urinary Bladder Cancer with Two "Clinically-Ready" Agents (Everolimus and Naproxen) when Administered in Combination  awarded by NIH - National Institutes of Health/DHHS
  • T006 HHSN26100010 (Old 509388 - T010) TORFP 2018-E07 Preclinical Development of a Chemopreventive Agent, 4-Methylumbelliferone (4-MU)  awarded by NIH - National Institutes of Health/DHHS
  • TORFP 2019-E03 75N91019D00019 75N91019F00130 Evaluation of Two Different Classes of Compounds (STAT3 Inhibitors and SERMs) for Prevention  awarded by NIH - National Institutes of Health/DHHS
  • TORFP 2019-E04 75N91010D00019 75N91019F00132 Colorectal Cancer Prevention by Novel EPA Analogue TP-252 and Naproxen in FAP and Lynch Syndrone Models  awarded by NIH - National Institutes of Health/DHHS
  • TORFP 2019-E06 75N91019D00019 75N91019F00131 Further Development of Colovac, a Multi-Antigen Multi-Peptide Vaccine, for Colon Cancer Prevention  awarded by NIH - National Institutes of Health/DHHS
  • The Role of Aryl Hyrocarbon Receptor in Colon Tumorigenesis  awarded by National Institute of Environmental Health Sciences/NIH/DHHS
  • Education And Training

  • University of Wisconsin Surgery, Chief Resident
  • University of Wisconsin-Madison Oncology, Postdoctoral Research
  • Mayo Clinic, Rochester Colon and Rectal Surgery, Residency
  • University of Wisconsin, Residency
  • University of Wisconsin-Madison Surgery, Residency
  • Doctor of Philosophy in Oncology and Cancer Biology, University of Wisconsin System : Madison 2003
  • Doctor of Medicine, University of Washington 1996
  • Bachelor of Science or Mathematics in Biomedical Sciences, Montana State University System : Bozeman 1992
  • Full Name

  • Gregory Kennedy