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Ferdinand Urthaler
Professor of Medicine
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furthalr@uab.edu
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Map of Science
Ferdinand Urthaler
Professor of Medicine
Positions
Senior Scientist (C)
,
Comprehensive Cardiovascular Center
,
School of Medicine
Professor (P)
,
Medicine - Cardiovascular Disease
,
Department of Medicine
Scientist (C)
,
Center for Cardiovascular Biology (Retired Org)
,
Medicine - Cardiovascular Disease
Professor (S)
,
Physiology & Biophysics (Retired Org)
,
Academic Joint Departments
Publications
Background
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
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2014
Inhibitors of arachidonate-regulated calcium channel signaling suppress triggered activity induced by the late sodium current
.
European Journal of Pharmacology
. 724:92-101.
2014
2013
Prolongation of minimal action potential duration in sustained fibrillation decreases complexity by transient destabilization
.
Cardioscience
. 98:155-156.
2013
2012
Evidence that 2-aminoethoxydiphenyl borate provokes fibrillation in perfused rat hearts via voltage-independent calcium channels
.
European Journal of Pharmacology
. 681:60-67.
2012
2011
Pharmacological evidence for Orai channel activation as a source of cardiac abnormal automaticity
.
European Journal of Pharmacology
. 668:208-216.
2011
2007
A pharmacological model for calcium overload-induced tachycardia in isolated rat left atria
.
European Journal of Pharmacology
. 576:122-131.
2007
2007
2-APB induces instability in rat left atrial mechanical activity
.
Journal of Cardiovascular Pharmacology
. 49:325-335.
2007
2004
Activation of leptin expression by an inhibitor of carnitine palmitoyltransferase-1
.
International Journal of Obesity
. 28:649-651.
2004
2002
Occupation of the prostaglandin E
2
-type 1 receptor increases rat atrial contractility via a Y-27632-sensitive pathway
.
Prostaglandins and Other Lipid Mediators
. 70:91-105.
2002
1999
Peroxynitrite irreversibly decreases diastolic and systolic function in cardiac muscle
.
Free Radical Biology and Medicine
. 27:1386-1392.
1999
1999
2-Tetradecylglycidic acid, an inhibitor of carnitine palmitoyltransferase-1, induces myocardial hypertrophy via the AT1 receptor
.
Journal of Molecular and Cellular Cardiology
. 31:1405-1412.
1999
1997
MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKC(ε) proteolysis in reperfused ferret hearts
.
Cardioscience
. 35:60-67.
1997
1994
Estimates of beat to beat handling of activator calcium using measurements of [Ca
2+
]
i
in aequorin loaded ferret cardiac muscle
.
Cardioscience
. 28:40-46.
1994
1994
Estimates of beat to beat handling of activator calcium using measurements of [Ca
2+
]
i
in aequorin loaded ferret cardiac muscle
.
Cardiovascular Research
. 28:40-46.
1994
1993
Beat-to-beat measurements of [Ca2+]i and force in ferret cardiac muscle after chemical loading of aequorin
.
American Journal of Physiology
. 265.
1993
1993
A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imaging
.
Cardiovascular Research
. 27:974-979.
1993
1993
A stable model of left ventricular dysfunction in an intact animal assessed with high fidelity pressure and cinemagnetic resonance imaging
.
Cardioscience
. 27:974-979.
1993
1993
Beat-to-beat measurements of [Ca
2+
](i) and force in ferret cardiac muscle after chemical loading of aequorin
.
American Journal of Physiology
. 265.
1993
1993
Effects of hypoxia on intracellular calcium and contractility [1]
.
Journal of Thoracic and Cardiovascular Surgery
. 105:1114-1116.
1993
1992
Quantitative effects of sympathetic and vagal nerve stimulations on sinus and AV junctional rhythms
.
Autonomic Neuroscience: Basic and Clinical
. 37:109-120.
1992
1991
Cardiac parasympathetic efferent activities during myocardial ischemia
.
Coronary Artery Disease
. 2:1031-1038.
1991
1991
Influence of ionic modification on electrical activity of Purkinje fibers obtained from dogs with 1-day-old myocardial infarction
.
Journal of Molecular and Cellular Cardiology
. 23:31-39.
1991
1990
Excitation-contraction coupling model to estimate the recirculating fraction of activator calcium in intact cardiac muscle
.
Canadian Journal of Physiology and Pharmacology
. 68:1041-1048.
1990
1989
A method for rapid quantification of phosphorus metabolites in the isolated rat heart using P-31 NMR
.
American journal of cardiac imaging
. 3:116-123.
1989
1989
Effects of ryanodine on contractile performance of intact length-clamped papillary muscle
.
Circulation Research
. 65:1270-1282.
1989
1988
Maximal twitch tension in intact length-clamped ferret papillary muscles evoked by modified postextrasystolic potentiation
.
Circulation Research
. 62:65-74.
1988
1987
The appearance and development of ventricular rhythm disorders in the 1st 24 hours after the start of experimental myocardial infarct in dogs
.
Kardiologiia
. 27:63-70.
1987
1987
The effects of negative chronotropic interventions on sinus node recovery time
.
Basic Research in Cardiology
. 82:92-100.
1987
1986
Differential effects of sympathetic activity on AV junctional automaticity and AV conduction
.
Basic Research in Cardiology
. 81:497-507.
1986
1986
Atrioventricular junctional tachycardia during heart block
.
Journal of the American College of Cardiology
. 8:657-660.
1986
1986
Cardiac autonomic efferent activity during baroreflex in puppies and adult dogs
1986
1986
Differential inotropic actions of ethmozine and ethacizin (diethylamine analog of ethmozine)
.
American Heart Journal
. 111:462-465.
1986
1986
Differential interaction of adrenergic and cholinergic effects on AV junctional automaticity and AV conduction
.
American Heart Journal
. 112:765-770.
1986
1986
Differential modulation of autonomic activity by ethmozin and ethacizin (analog of ethmozin) on the canine sinus node and atrioventricular junction
.
Journal of the American College of Cardiology
. 8:86A-94A.
1986
1986
Differential sympathetic-parasympathetic interactions in sinus node and AV junction
1986
1986
Effects of ethacizin (diethylamino analogue of ethmozin) upon sympathetic and parasympathetic efferent activity to the canine heart
.
Kardiologiia
. 26:54-60.
1986
1986
Effects of the diethylamino analog of ethmozin (ethacizin) upon sympathetic and parasympathetic efferent activity to the canine heart
.
Journal of Pharmacology and Experimental Therapeutics
. 236:75-79.
1986
1986
Role of calcium channel blockers in clinical medicine
.
American Journal of the Medical Sciences
. 292:217-230.
1986
1986
Serial production of controlled periods of temporary heart block used to unmask and assess latent ventricular automaticity during experimental acute myocardial ischemia
.
Journal of the American College of Cardiology
. 8:95A-103A.
1986
1986
The direct negative inotropic effect of gossypol
.
Journal of Ethnopharmacology
. 17:31-36.
1986
1986
Ventricular echo beats during ventricular pacing or junctional bradycardia: Studies in the normal canine heart
.
American Heart Journal
. 111:672-678.
1986
1985
Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction.
.
American Journal of Physiology
. 248.
1985
1985
Differences in the determinants of overdrive suppression between sinus rhythm and slow atrioventricular junctional rhythm
.
Circulation Research
. 57:182-191.
1985
1985
Negative chronotropic and parasympatholytic effects of alinidine on canine sinus node and AV junction
1985
1984
Arrhythmias and antiarrhythmic drugs.
.
The Alabama journal of medical sciences
. 21:275-283.
1984
1984
Indirect stimulatory action of the calcium channel blocker AQA-39
.
Journal of Pharmacology and Experimental Therapeutics
. 230:336-340.
1984
1984
No electrical instability after intracoronary streptokinase administered into sinus node or AV node of dogs
.
American Heart Journal
. 107:902-905.
1984
1984
Parasympathetic and sympathetic efferent traffic during a cardiogenic hypertensive chemoreflex
.
Cardioscience
. 18:583-590.
1984
1983
Acute effects of amiodarone upon the canine sinus node and atrioventricular junctional region
.
Journal of Clinical Investigation
. 71:1457-1466.
1983
1983
Differential effect of verapamil isomers on sinus node and AV junctional region
1983
1983
Differential effect of verapamil isomers on sinus node and AV junctional region.
.
American Journal of Physiology
. 244.
1983
1983
Studies of changes in breathing and blood pressure accompanying a cardiogenic hypertensive chemoreflex compared in conscious and anesthetized dogs
.
American Heart Journal
. 106:547-553.
1983
1983
Ventricular flutter during treatment with amiodarone
.
American Journal of Cardiology
. 51:609-610.
1983
1982
Post-excitatory depression in thoracic sympathetic efferent neural traffic during a cardiogenic hypertensive chemoreflex
.
Basic Research in Cardiology
. 77:423-430.
1982
1982
The direct negative chronotropic action of prazosin on the canine sinus node
.
Journal of Pharmacology and Experimental Therapeutics
. 221:801-805.
1982
1982
The immediate electrophysiologic effects of amiodarone on the canine sinus node and AV junctional region
.
American Journal of Cardiology
. 49:981.
1982
1982
Ultrastructure of a coronary chemoreceptor of dogs and cats
.
Journal of Molecular and Cellular Cardiology
. 14:711-724.
1982
1981
Absence of electrophysiological effect by intracoronary streptokinase administered directly into arteries supplying sinus node or AV node of dog
.
Clinical research
. 29.
1981
1981
Clonidine attenuation of a cardiogenic hypertensive chemoreflex
.
Hypertension
. 3:240-244.
1981
1981
Direct effects of prazosin on the canine sinus node
.
American Journal of Cardiology
. 47:389.
1981
1981
Effects of adenosine on mechanical performance and electrical activity in the canine heart
.
Journal of Pharmacology and Experimental Therapeutics
. 216:254-260.
1981
1981
Effects of selectively produced changes in cardiac rhythm or conduction upon flow in the superior vena cava
.
Journal of Thoracic and Cardiovascular Surgery
. 82:447-456.
1981
1981
Effects of tetraethylammonium and 4-aminopyridine upon canine sinus node
.
Journal of Molecular and Cellular Cardiology
. 13:889-901.
1981
1981
Electrical activity in canine sinus node cells during arrest produced by acetylcholine
.
Journal of Molecular and Cellular Cardiology
. 13:349-357.
1981
1981
Rate dependence of the negative inotropic action of adenosine
.
Clinical research
. 29.
1981
1981
The differential and rate dependent effect of the isomers of verapamil on sinus node and AV junctional automaticity
.
Physiologist
. 24.
1981
1981
The immediate electrophysiologic effects of amiodarone on the canine sinus node and AV junctional region
.
Clinical research
. 29.
1981
1980
Analysis of sympathetic discharges during cardiogenic hypertensive chemoreflex
.
American Journal of Physiology
. 7.
1980
1980
Blocking Effects of Cyproheptadine and Methysergide upon Two Different Cardiovascular Responses to Serotonin
.
Experimental Biology and Medicine
. 165:420-423.
1980
1980
Changing negative inotropic effect of acetylcholine in maturing canine cardiac muscle
1980
1980
Changing negative inotropic effect of acetylcholine in maturing canine cardiac muscle.
.
American Journal of Physiology
. 238.
1980
1980
Dilatation of coronary artery stenoses after isosorbide dinitrate in man
.
Heart
. 43:546-549.
1980
1980
Dilatation of coronary stenoses after isosorbide dinitrate
.
Clinical Research in Cardiology
. 69:243.
1980
1980
Direct effects of prazosin on the canine sinus node
.
American Journal of Cardiology
. 28.
1980
1980
Hierarchy of supraventricular pacemakers
.
Journal of Thoracic and Cardiovascular Surgery
. 80:750-753.
1980
1980
Quantitative difference in 'critical' stenosis between right and left coronary artery in man
.
Circulation
. 62:1188-1196.
1980
1980
Reflex heart block. Baroreflex, chemoreflex and bronchopulmonary reflex causes
.
American Journal of Cardiology
. 45:1182-1188.
1980
1980
Regional flow patterns during the serotonin-induced cardiogenic hypertensive chemoreflex
.
Cardioscience
. 14:169-176.
1980
1980
Selective effects of clonidine on the canine sinus node
.
Journal of Pharmacology and Experimental Therapeutics
. 214:223-228.
1980
1979
Morphological changes in the right ventricular septomarginal trabecula (false tendon) during maturation and ageing in the dog heart
.
Journal of Anatomy
. 129:805-817.
1979
1979
Termination of 'ventricular' arrhythmias from digoxin by selective production of complete atrioventricular block with physostigmine in the dog
.
Journal of Pharmacology and Experimental Therapeutics
. 211:561-570.
1979
1979
Anatomic and physiologic considerations of a cardiogenic hypertensive chemoreflex
.
American Journal of Cardiology
. 44:852-859.
1979
1979
Experimental studies on the pathogenesis of asystole after verapamil in the dog
.
American Journal of Cardiology
. 44:651-656.
1979
1979
Asystole after nifedipine
.
Clinical research
. 27.
1979
1979
Chronotropic and dromotropic effects of histamine on the canine heart
.
Chest
. 75:597-604.
1979
1979
Correlative electrophysiological and anatomical studies concerning the site of origin of escape rhythm during complete atrioventricular block in the dog
.
Circulation Research
. 45:108-119.
1979
1979
Dual dependence on both Ca
2+
and Mg
2+
for electrical stability in cells of canine false tendon
.
Journal of Molecular and Cellular Cardiology
. 11.
1979
1979
Effects of clonidine upon the thoracic sympathetic efferent discharges of a cardiogenic hypertensive chemoreflex
.
Physiologist
. 22:50.
1979
1979
Effects of verapamil on automaticity and conduction with particular reference to tachyphylaxis
.
International Journal of Cardiology
. 9:345-368.
1979
1979
Electrophysiological effects of magnesium on cells in the canine sinus node and false tendon
.
Circulation Research
. 44:182-188.
1979
1979
Fine Structure of Myotendinous Junctions of Ventricular Papillary Muscles of the Cat (Feus Domestica) and Bat (Myotis Lucifugus)
1979
1979
Mechanism of postarrhythmic renal vasoconstriction in the anesthetized dog
.
Journal of Clinical Investigation
. 64:17-31.
1979
1978
Progressive postnatal changes in sinus node response to atropine and propranolol.
.
American Journal of Physiology
. 234.
1978
1978
Canine atrial and ventricular muscle mechanics studies as a function of age
.
Circulation Research
. 42:703-713.
1978
1978
Chronotropic effects of tetraethylammonium and 4-aminopyridine in canine sinus node pacemaker cells
.
Circulation
. 58.
1978
1978
Hemodynamic components of a cardiogenic hypertensive chemoreflex in dogs
.
Circulation Research
. 42:135-142.
1978
1978
Neural pathways of a cardiogenic hypertensive chemoreflex
.
American Journal of Physiology
. 4.
1978
1978
Neural pathways of a cardiogenic hypertensive chemoreflex
1978
1978
New arterial hypertension during myocardial infarction
.
Southern Medical Journal
. 71:289-292.
1978
1978
Progressive postnatal changes in sinus node response to atropine and propranolol
1978
1978
The effect of aging on ventricular contractile performance
.
American Heart Journal
. 96:481-485.
1978
1978
The mechanism of post-arrhythmic renal vasoconstriction in the dog
.
Circulation
. 58.
1978
1977
A mathematical model of automaticity in the sinus node and AV junction based on weakly coupled relaxation oscillators
.
Journal of Biomedical Informatics
. 10:529-543.
1977
1977
Chemoreceptors of the heart
.
Transactions of the American Clinical and Climatological Association
. Vol.88:18-31.
1977
1977
Chronotropic and dromotropic effects of histamine (H 1 and H 2) agonists upon the canine heart
.
Physiologist
. 20:39.
1977
1977
Cyproheptadine Blockade of a Cardiogenic Hypertensive Chemoreflex
.
Experimental Biology and Medicine
. 154:578-581.
1977
1977
Differential sensitivity to neurotransmitters in denervated canine sinus node
.
American Journal of Physiology
. 233.
1977
1976
Fine structure of the conduction system and working myocardium in the little brown bat, Myotis lucifugus.
.
Recent advances in studies on cardiac structure and metabolism
. 12:81-91.
1976
1976
Both direct and neurally mediated components of the chronotropic actions of aminophylline
.
Chest
. 70:24-32.
1976
1976
Comparison of the inotropic action of morphine and ketamine studied in canine cardiac muscle.
.
Journal of Thoracic and Cardiovascular Surgery
. 72:142-149.
1976
1976
Influence of [Mg
2+
] on activity of sinus node pacemaker cells
.
Circulation
. 54.
1976
1976
Sinus bradyarrhythmia and impaired response to norepinephrine caused by low extracellular sodium
.
Circulation
. 54.
1976
1976
Spontaneous action potentials of cells in the canine sinus node
.
Circulation Research
. 39:76-82.
1976
1975
A comparison of His bundle electrograms recorded from the aortic root and from a plaque sutured near the His bundle
1975
1975
Absence of supersensitivity to acetylcholine in the extrinsically denervated canine sinus node
.
Physiologist
. 18:236.
1975
1975
Analysis of components in a cardiogenic hyertensive chemoreflex
.
Circulation
. 52:179-192.
1975
1975
Canine atrial and ventricular muscle mechanics studied as a function of age
.
Circulation
. 52.
1975
1975
Comparison of contractile performance of canine atrial and ventricular muscles
.
Circulation Research
. 37:762-771.
1975
1975
Direct and vagally mediated chronotropic effects of morphine studied by selective perfusion of the sinus node of awake dogs
.
Chest
. 68:222-228.
1975
1974
Comparative effects of glucagon on automaticity of the sinus node and atrioventricular junction.
.
American Journal of Physiology
. 227:1415-1421.
1974
1974
Electrophysiological and mathematical characteristics of the escape rhythm during complete AV block
.
Cardioscience
. 8:173-186.
1974
1974
Fine structure of the bundle branches
.
Heart
. 36:1-18.
1974
1974
Morphine selectively perfused into the sinus node of awake dogs
.
Circulation
. 50.
1974
1974
Prostaglandins and autonomic control of the sinus node
1974
1974
Selective effects of pentobarbital on automaticity and conduction in the intact canine heart
.
Cardioscience
. 8:46-57.
1974
1973
Comparatve dependence on adrenergic neural tone by automaticity in the sinus node and in the atrioventricular junction
.
Journal of Pharmacology and Experimental Therapeutics
. 187:269-279.
1973
1973
Effect of tetrodotoxin on A-V conduction and A-V junctional rhythm.
.
American Journal of Physiology
. 224:1155-1161.
1973
1973
Mathematical relationship between automaticity of the sinus node and the AV junction
.
American Heart Journal
. 86:189-195.
1973
1973
Morphine and autonomic control of the sinus node
.
Chest
. 64:203-212.
1973
1973
Neurogenic influence on the atrial repolarization (P-T
p
) segment
.
American Journal of Cardiology
. 32:799-807.
1973
1973
Prostaglandins and autonomic control of the sinus node
.
Clinical research
. 22.
1973
1972
Effects of adenosine and ATP on AV conduction and on AV junctional rhythm
1972
1971
Pharmacologic production of atrioventricular block with and without initial bundle branch block.
.
Journal of Pharmacology and Experimental Therapeutics
. 179:338-346.
1971
1971
Changes in the clinical picture of infectious endocarditis
.
Swiss Medical Weekly
. 101:105-109.
1971
1970
Löfgren's Syndrome. Incidence and course of Boeck's disease
.
Swiss Medical Weekly
. 100:1111-1113.
1970
1969
Rhythm disorders in acute myocardial infarct. Experience with 370 patients at a coronary care unit
.
Helvetica medica acta. Supplementum
. 49:199.
1969
Background
Education And Training
Doctor of Medicine,
University of Zurich
1963
Contact
Full Name
Ferdinand
Urthaler