Farah Lubin

Farah Lubin
Professor

Scientist (C), Integrative Center for Aging Research , School of Medicine
Scientist (C), Center for Clinical and Translational Science (CCTS) , General Clinical Research Center
Scientist (C), Comprehensive Neuroscience Center , General Clinical Research Center
Associate Scientist (C), Neurodegeneration and Experimental Therapeutics (CNET) , Neurology
Scientist (C), Alzheimer's Disease Center , Neurology
Investigator (C), Evelyn F. McKnight Brain Institute , Neurology
Scientist (C), Global Center for Craniofacial, Oral and Dental Disorders (GC-CODED) , School of Dentistry
Scientist (C), Civitan International Research Center , Academic Joint Departments
Associate Scientist (C), Center for Glial Biology in Medicine , Academic Joint Departments
Professor (P), Neurobiology , Academic Joint Departments
Associate Professor (S), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments

Selected Publications

Academic Article

Year	Title	Altmetric
2022	The impact of methodology on the reproducibility and rigor of DNA methylation data. Scientific Reports. 12. 2022
2021	A putative role for lncRNAs in epigenetic regulation of memory: Memory Regulation via lncRNAs 2021
2021	Ubiquitination of Histone H2B by Proteasome Subunit RPT6 Controls Histone Methylation Chromatin Dynamics During Memory Formation. Biological Psychiatry. 89:1176-1187. 2021
2020	Analysis of Blood DNA Methylation in Early-Life Seizures. Epilepsy Currents. 20:393-395. 2020
2020	Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control. Journal of Controlled Release. 324:172-180. 2020
2020	A benchtop approach to the location specific blood brain barrier opening using focused ultrasound in a rat model. Journal of Visualized Experiments. 2020:1-13. 2020
2020	The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation. Biological Psychiatry. 87:577-587. 2020
2020	Epigenetic Therapeutic Intervention for a Rare Epilepsy Disorder. Epilepsy Currents. 20:111-112. 2020
2020	Surface Effects of Ultrasmall Iron Oxide Nanoparticles on Cellular Uptake, Proliferation, and Multipotency of Neural Stem Cells. ACS Applied Nano Materials. 3:1542-1552. 2020
2019	Telencephalon transcriptome analysis of chronically stressed adult zebrafish. Scientific Reports. 9. 2019
2019	Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment. Science Signaling. 12. 2019
2019	Chromodomain Helicase DNA-Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis. Stem Cells. 37:453-462. 2019
2019	Human and rodent temporal lobe epilepsy is characterized by changes in O-GlcNAc homeostasis that can be reversed to dampen epileptiform activity. Neurobiology of Disease. 124:531-543. 2019
2019	O-GlcNAc and EZH2-mediated epigenetic regulation of gene expression during consolidation of fear memories. Learning and Memory. 26:373-379. 2019
2018	A gut feeling about seizures. Epilepsy Currents. 18:389-390. 2018
2018	EZH2 methyltransferase activity controls pten expression and mTOR signaling during fear memory reconsolidation 2018
2018	Prefrontal cortex-dependent innate behaviors are altered by selective knockdown of Gad1 in neuropeptide Y interneurons. PLoS One. 13. 2018
2018	The Epigenetics of Epilepsy and Its Progression 2018
2017	Amygdalar expression of the microRNA miR-101a and its target Ezh2 contribute to rodent anxiety-like behaviour. European Journal of Neuroscience. 46:2241-2252. 2017
2017	Dynamic association of epigenetic H3K4me3 and DNA 5hmC marks in the dorsal hippocampus and anterior cingulate cortex following reactivation of a fear memory. Neurobiology of Learning and Memory. 142:66-78. 2017
2016	Age-related changes in Egr1 transcription and DNA methylation within the hippocampus 2016
2016	Noradrenaline goes nuclear: Epigenetic modifications during long-lasting synaptic potentiation triggered by activation of β-adrenergic receptors 2016
2016	Increased expression of BDNF transcript with exon VI in hippocampi of patients with pharmaco-resistant temporal lobe epilepsy. Neuroscience. 314:12-21. 2016
2016	Regulatory RNAs and control of epigenetic mechanisms: Expectations for cognition and cognitive dysfunction. Epigenomics. 8:135-151. 2016
2015	NF-ΚB mediates gadd45β expression and DNA demethylation in the hippocampus during fear memory formation. Frontiers in Molecular Neuroscience. 8. 2015
2015	Methionine increases BDNF DNA methylation and improves memory in epilepsy. Annals of Clinical and Translational Neurology. 2:401-416. 2015
2015	Environmental enrichment reverses histone methylation changes in the aged hippocampus and restores age-related memory deficits. Biology. 4:298-313. 2015
2014	Epigenetic mechanisms of memory formation and reconsolidation. Neurobiology of Learning and Memory. 115:116-127. 2014
2014	NMDA receptor- and ERK-dependent histone methylation changes in the lateral amygdala bidirectionally regulate fear memory formation. Learning and Memory. 21:351-362. 2014
2014	The epigenetic basis of memory formation and storage. Progress in molecular biology and translational science. 128:1-27. 2014
2013	Sirtuin activity in dentate gyrus contributes to chronic stress-induced behavior and extracellular signal-regulated protein Kinases 1 and 2 cascade changes in the hippocampus. Biological Psychiatry. 74:927-935. 2013
2013	Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience. 248:602-619. 2013
2013	Histone lysine methylation: Critical regulator of memory and behavior. Reviews in the Neurosciences. 24:375-387. 2013
2012	Direct bisulfite sequencing for examination of DNA methylation with gene and nucleotide resolution from brain tissues. Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]. 1. 2012
2012	HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons 2012
2012	Epileptogenesis: Can the science of epigenetics give us answers?. Epilepsy Currents. 12:105-110. 2012
2012	G9a/GLP histone lysine dimethyltransferase complex activity in the hippocampus and the entorhinal cortex is required for gene activation and silencing during memory consolidation 2012
2011	Age-related changes in Arc transcription and DNA methylation within the hippocampus. Neurobiology of Aging. 32:2198-2210. 2011
2011	Epigenetic mechanisms in experience-driven memory formation and behavior. Epigenomics. 3:649-664. 2011
2011	Epigenetic gene regulation in the adult mammalian brain: Multiple roles in memory formation. Neurobiology of Learning and Memory. 96:68-78. 2011
2011	Epigenetic mechanisms: Critical contributors to long-term memory formation 2011
2010	The epigenetics of memory storage in the brain.. Cellscience. 7:1-8. 2010
2010	Histone methylation regulates memory formation 2010
2009	Epigenetic mechanisms in schizophrenia 2009
2009	The dynamics of HDAC activity on memory formation.. Cellscience. 6:44-48. 2009
2009	Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene. Biological Psychiatry. 65:760-769. 2009
2008	Epigenetics in the nervous system 2008
2008	Epigenetic regulation of bdnf gene transcription in the consolidation of fear memory 2008
2008	C-Rel, an NF-κB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation. Learning and Memory. 15:539-549. 2008
2008	Striatal histone modifications in models of levodopa-induced dyskinesia. Journal of Neurochemistry. 106:486-494. 2008
2007	Nuclear factor-κB regulates seizure threshold and gene transcription following convulsant stimulation. Journal of Neurochemistry. 103:1381-1395. 2007
2007	The IκB Kinase Regulates Chromatin Structure during Reconsolidation of Conditioned Fear Memories. Neuron. 55:942-957. 2007
2007	Effect of the α3β1 integrin on the IL-1 stimulated activation of c-Jun N-terminal kinase (JNK) in CACO-2 cells. Cytokine. 37:163-170. 2007
2006	Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. Journal of Biological Chemistry. 281:15763-15773. 2006
2006	Regulation of surface localization of the small conductance Ca ²⁺-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase. Journal of Biological Chemistry. 281:11769-11779. 2006
2005	Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulated protein kinase. Neuroscience. 133:969-981. 2005
2004	α3β1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-κB activation. Cellular Immunology. 231:30-39. 2004
2003	Regulation of epithelial cell cytokine responses by the α3β1 integrin. Immunology. 108:204-210. 2003

Book

Year	Title	Altmetric
2014	Preface. Ed. 128. 2014

Chapter

Year	Title	Altmetric
2012	Epigenetic mechanisms in central nervous system disorders. 321-333. 2012

Education And Training

Doctor of Philosophy in Biology / Biological Sciences, State University of New York System : Binghamton 2001

Full Name

Farah Lubin

Farah Lubin
Professor

Publications

Selected Publications

Academic Article

Book

Chapter

Research

Principal Investigator On

Investigator On

Teaching

Teaching Activities

Background

Education And Training

Contact

Full Name

Farah Lubin Professor

E-mail

Visualizations

Publications

Selected Publications

Academic Article

Book

Chapter

Research

Principal Investigator On

Investigator On

Teaching

Teaching Activities

Background

Education And Training

Contact

Full Name

Farah Lubin
Professor