Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 The cross-talk of NOTCH and GSK-3 signaling in colon and other cancersBBA: Molecular Cell Research.  1867. 2020
2020 Crafting a team-based, interprofessional undergraduate research honors curriculum in the health professionsJournal of Allied Health.  49:E57-E62. 2020
2016 The Notch pathway in colorectal cancerInternational Journal of Cancer.  138:1835-1842. 2016
2015 Notch-1 Promotes Stemness and Epithelial to Mesenchymal Transition in Colorectal CancerJournal of Cellular Biochemistry.  116:2517-2527. 2015
2014 NOTCH and PTEN in prostate cancerAdvances in Biological Regulation.  56:51-65. 2014
2012 Developmental pathways in colon cancer: Crosstalk between WNT, BMP, Hedgehog and NotchCell Cycle.  11:4344-4351. 2012
2011 Label-free classification of cultured cells through diffraction imagingBiomedical Optics Express.  2:1717-1726. 2011
2009 Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expressionJournal of Cellular Biochemistry.  107:992-1001. 2009
2007 CBF-1 (RBP-Jκ) binds to the PTEN promoter and regulates PTEN gene expressionCell Cycle.  6:80-84. 2007
2006 The MLL partial tandem duplication in acute myeloid leukaemiaBritish Journal of Haematology.  135:438-449. 2006
2006 Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistanceAdvances in Enzyme Regulation.  46:249-279. 2006
2005 The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: What's genetics got to do with it?Expert Opinion on Therapeutic Targets.  9:1009-1030. 2005
2005 Acquired immunodeficiency syndrome associated lymphomaFrontiers in Bioscience.  10:2972-2977. 2005
2005 Activated EGFR promotes the survival of B-lineage acute leukemia in the absence of stromal cellsCell Cycle.  4:483-487. 2005
2005 Conditional EGFR promotes cell cycle progression and prevention of apoptosis in the absence of autocrine cytokinesCell Cycle.  4:822-830. 2005
2005 Effects of endogenous epidermal growth factor receptor signaling on DNA synthesis and ERK activation in a cytokine-dependent hematopoietic cell lineCell Cycle.  4:818-821. 2005
2005 Increased protein expression of the PTEN tumor suppressor in the presence of constitutively active notch-1Cell Cycle.  4:1389-1395. 2005
2005 Upping the bid on engineered inducible cell deathCancer Biology and Therapy.  4:537. 2005
2004 The complexity of PTEN: Mutation, marker and potential target for therapeutic interventionExpert Opinion on Therapeutic Targets.  8:537-550. 2004
2002 Microarray analysis of a t(4;11)q(21;23) cell line with B-lineage developmental potential reveals a distinct pattern of Hox geneBlood.  100:195B-195B. 2002
2001 Pro-B-cell to pre-B-cell development in B-lineage acute lymphoblastic leukemia expressing the MLL/AF4 fusion proteinBlood.  98:3398-3405. 2001
2001 VH gene replacement in thymocytesJournal of Immunology.  166:855-860. 2001
2000 De novo IgH gene segment rearrangement leads to functional pre-BCR expression in a novel B-lineage all cell like expressing MLL/AF4.Blood.  96:617A-+. 2000
2000 Endogenous Notch-1 cleavage in human B-lineage cells.Blood.  96:615A-+. 2000
2000 Microenvironmental influences on human B-cell developmentImmunological Reviews.  175:175-186. 2000
1999 Notch expression and signaling in normal and leukemic human B-lineage cells.Blood.  94:436A-436A. 1999
1999 IgM heavy chain complementarity-determining region 3 diversity is constrained by genetic and somatic mechanisms until two months after birthJournal of Immunology.  162:6060-6070. 1999
1999 The expression of long HCDR3 intervals is constrained by both genetic and somatic mechanisms during human B-cell ontogenyJournal of Investigative Medicine.  47. 1999
1998 V(H) gene replacement occurs in the spleen and bone marrow of non-autoimmune quasi-monoclonal miceEuropean Journal of Immunology.  28:3362-3370. 1998
1998 Molecular mechanisms involved in receptor editing at the Ig heavy chain locusInternational Immunology.  10:241-246. 1998
1998 Sequence analysis of the mouse RAG locus intergenic regionAutoimmunity.  5:215-222. 1998
1998 Sequence of the Rag1 and Rag2 intergenic region in zebrafish (Danio rerio)Autoimmunity.  5:211-214. 1998
1997 Ig D(H) gene segment transcription and rearrangement before surface expression of the pan-B-cell marker CD19 in normal human bone marrowBlood.  90:736-744. 1997
1996 The J chain gene is transcribed during B and T lymphopoiesis in humansJournal of Immunology.  156:4240-4244. 1996
1995 Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitorsJournal of Experimental Medicine.  182:973-982. 1995
1995 ACTIVATION AND REGULATION OF HUMAN DJC-MU-GENE SEGMENT REARRANGEMENT PRIOR TO SURFACE EXPRESSION OF THE B-CELL MARKER-CD19Journal of Cellular Biochemistry.  112-112. 1995
1995 Analysis of DHQ52 Gene Segment Transcription and Rearrangement During B‐Cell Development in Human Fetal Bone MarrowAnnals of the New York Academy of Sciences.  764:228-230. 1995
1995 Developmental Regulation of the Human Antibody RepertoireAnnals of the New York Academy of Sciences.  764:242-260. 1995
1994 REGULATION OF EARLY HUMAN B-LYMPHOCYTE DIFFERENTIATION BY INTERLEUKIN-7Experimental Hematology.  22:717-717. 1994
1993 DEVELOPMENTAL REGULATION OF IMMUNOGLOBULIN DH AND JH GENE SEGMENT EXPRESSION IN MANJournal of Immunology.  150:A151-A151. 1993
1993 TRANSGENIC EXPRESSION OF HUMAN TERMINAL DEOXYNUCLEOTIDYL-TRANSFERASE IN MOUSE THYMUSJournal of Immunology.  150:A33-A33. 1993
1993 DEVELOPMENTAL REGULATION OF DH AND JH GENE SEGMENT REARRANGEMENT IN MANJournal of Cellular Biochemistry.  220-220. 1993
1992 ANALYSIS OF IMMUNOGLOBULIN DJ TRANSCRIPTS FROM BONE-MARROW AND FETAL LIVER INDICATES DEVELOPMENTAL REGULATION OF DH AND J(H) GENE SEGMENT REARRANGEMENTClinical research.  40:A820-A820. 1992

Chapter

Year Title Altmetric
2007 Critical roles of the Raf/MEK/ERK pathway in apoptosis and drug resistance.  101-134. 2007

Teaching Activities

  • BMD202 - Surv of BioMed Sciences Lit (Spring Term 2016)
  • BMD202 - Surv of BioMed Sciences Lit (Spring Term 2016)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2014)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2015)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2016)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2016)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2017)
  • BMD320 - Surv of Cell Biology for HP (Fall Term 2017)
  • BMD330 - Clin Microbiology for HP (Spring Term 2015)
  • BMD330 - Clin Microbiology for HP (Spring Term 2016)
  • BMD330 - Clin Microbiology for HP (Spring Term 2017)
  • BMD330 - Clin Microbiology for HP (Spring Term 2017)
  • BMD330 - Clin Microbiology for HP (Spring Term 2018)
  • BMD330 - Clin Microbiology for HP (Spring Term 2018)
  • BMD330 - Clin Microbiology for HP (Spring Term 2022)
  • BMD430 - Clin Immunology for HP (Fall Term 2015)
  • BMD430 - Clin Immunology for HP (Fall Term 2018)
  • BMD430 - Clin Immunology for HP (Fall Term 2018)
  • BMD495 - Pract in Biomedical Sciences (Fall Term 2021)
  • BMD495 - Pract in Biomedical Sciences (Spring Term 2022)
  • BMD497 - Dir BMD Research Studies (Fall Term 2016)
  • BMD497 - Dir BMD Research Studies (Fall Term 2016)
  • BMD497 - Dir BMD Research Studies (Spring Term 2017)
  • BMD497 - Dir BMD Research Studies (Summer Term 2015)
  • BMD497 - Dir BMD Research Studies (Summer Term 2016)
  • BMD497 - Dir BMD Research Studies (Summer Term 2017)
  • CLS518 - Immunology (Fall Term 2014)
  • CLS518 - Immunology (Fall Term 2015)
  • HRP200 - Responsible Conduct Research (Fall Term 2017)
  • HRP200 - Responsible Conduct Research (Fall Term 2018)
  • HRP200 - Responsible Conduct Research (Fall Term 2019)
  • HRP200 - Responsible Conduct Research (Fall Term 2020)
  • HRP200 - Responsible Conduct Research (Spring Term 2018)
  • HRP200 - Responsible Conduct Research (Spring Term 2019)
  • HRP200 - Responsible Conduct Research (Spring Term 2020)
  • HRP200 - Responsible Conduct Research (Spring Term 2021)
  • HRP200 - Responsible Conduct Research (Summer Term 2018)
  • HRP200 - Responsible Conduct Research (Summer Term 2019)
  • HRP200 - Responsible Conduct Research (Summer Term 2020)
  • HRP200 - Responsible Conduct Research (Summer Term 2021)
  • HRP200 - Responsible Conduct Research (Summer Term 2021)
  • HRP401 - Honors Seminar I (Fall Term 2017)
  • HRP401 - Honors Seminar I (Fall Term 2018)
  • HRP401 - Honors Seminar I (Fall Term 2019)
  • HRP401 - Honors Seminar I (Fall Term 2020)
  • HRP402 - Honors Seminar II (Spring Term 2018)
  • HRP402 - Honors Seminar II (Spring Term 2019)
  • HRP402 - Honors Seminar II (Spring Term 2020)
  • HRP402 - Honors Seminar II (Spring Term 2021)
  • HRP405 - Team-Based Prob Solving in HP (Fall Term 2017)
  • HRP405 - Team-Based Prob Solving in HP (Fall Term 2018)
  • HRP405 - Team-Based Prob Solving in HP (Fall Term 2019)
  • HRP405 - Team-Based Prob Solving in HP (Fall Term 2020)
  • HRP405 - Team-Based Prob Solving in HP (Spring Term 2020)
  • HRP410 - Honors Project (Spring Term 2016)
  • HRP410 - Honors Research Project (Spring Term 2018)
  • HRP411 - Honors Community Service Proj (Fall Term 2017)
  • HRP411 - Honors Community Service Proj (Fall Term 2018)
  • HRP411 - Honors Community Service Proj (Fall Term 2019)
  • HRP411 - Honors Community Service Proj (Fall Term 2019)
  • HRP411 - Honors Community Service Proj (Fall Term 2020)
  • HRP411 - Honors Community Service Proj (Fall Term 2020)
  • HRP411 - Honors Community Service Proj (Spring Term 2018)
  • HRP411 - Honors Community Service Proj (Spring Term 2019)
  • HRP411 - Honors Community Service Proj (Spring Term 2020)
  • HRP411 - Honors Community Service Proj (Spring Term 2021)
  • HRP411 - Honors Community Service Proj (Summer Term 2018)
  • HRP411 - Honors Community Service Proj (Summer Term 2019)
  • HRP414 - Volunteer Research Experience (Fall Term 2020)
  • HRP414 - Volunteer Research Experience (Spring Term 2021)
  • HRP414 - Volunteer Research Experience (Summer Term 2021)
  • HRP415 - Mentored Res in the Hlth Profs (Fall Term 2017)
  • HRP415 - Mentored Res in the Hlth Profs (Fall Term 2018)
  • HRP415 - Mentored Res in the Hlth Profs (Fall Term 2019)
  • HRP415 - Mentored Res in the Hlth Profs (Fall Term 2020)
  • HRP415 - Mentored Res in the Hlth Profs (Spring Term 2018)
  • HRP415 - Mentored Res in the Hlth Profs (Spring Term 2019)
  • HRP415 - Mentored Res in the Hlth Profs (Spring Term 2020)
  • HRP415 - Mentored Res in the Hlth Profs (Spring Term 2021)
  • HRP415 - Mentored Res in the Hlth Profs (Summer Term 2018)
  • HRP415 - Mentored Res in the Hlth Profs (Summer Term 2019)
  • HRP415 - Mentored Res in the Hlth Profs (Summer Term 2020)
  • HRP415 - Mentored Res in the Hlth Profs (Summer Term 2021)
  • HRP475 - Special Tops in HS or Clin Res (Fall Term 2018)
  • HRP475 - Special Tops in HS or Clin Res (Spring Term 2018)
  • HRP475 - Special Tops in HS or Clin Res (Spring Term 2020)
  • HRP475 - Special Tops in HS or Clin Res (Summer Term 2018)
  • HRP475 - Special Tops in HS or Clin Res (Summer Term 2019)
  • HRP475 - Special Tops in HS or Clin Res (Summer Term 2021)
  • HRP490 - Capstone: Exp in Healh Profess (Fall Term 2020)
  • MT418 - Immunology (Fall Term 2014)
  • MT418 - Immunology (Fall Term 2015)
  • Education And Training

  • Doctor of Philosophy in Microbiology, University of Alabama at Birmingham 1995
  • Full Name

  • Fred Bertrand