I am generally interested in discovering and characterizing mechanisms by which cells control gene expression. Much of my career has focused on the regulation of ribosomal RNA synthesis, using an array of biochemical, genetic, and genomic approaches. As an independent academic investigator, I am privileged to be involved in the act of discovery every day. In addition, I take my roles as mentor and educator equally serious. Our goal is to create an environment where we can aggressively ask and answer important questions while training the next generation of scientists to be careful, critical, and content in the pursuit of knowledge.