• Lori L. Davis, MD, is Clinical Professor of Psychiatry in the Department of Psychiatry and Behavioral Neurobiology, University of Alabama Health System, in Birmingham and Tuscaloosa, AL. In addition, she is Associate Chief of Staff for Research and Development Service for the VA Medical Center in Tuscaloosa, Alabama. Dr. Davis received her undergraduate degree in Studio Art from Duke University, earned her MD from the University of North Carolina at Chapel Hill, and completed a psychiatry residency at the University of Alabama at Birmingham.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Childhood adversity and adulthood major depressive disorder.General Hospital Psychiatry.  76:36-44. 2022
    2020 A Randomized, Placebo-Controlled Trial of Mirtazapine for the Treatment of Posttraumatic Stress Disorder in VeteransJournal of Clinical Psychiatry.  81. 2020
    2018 Reply to: It Is Time to Look for New Treatments for Posttraumatic Stress Disorder: Can Sympathetic System Modulation Be an Answer?Biological Psychiatry.  84:e19-e20. 2018
    2018 Veterans individual placement and support towards advancing recovery: Methods and baseline clinical characteristics of a multisite studyPsychiatric Rehabilitation Journal.  41:55-66. 2018
    2017 It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working GroupBiological Psychiatry.  82:e51-e59. 2017
    2017 Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial.JAMA: Journal of the American Medical Association.  318:132-145. 2017
    2017 An Evidence-Based Review of Early Intervention and Prevention of Posttraumatic Stress DisorderCommunity Mental Health Journal.  53:183-201. 2017
    2017 A Pilot Study of the Effects of Mindfulness-Based Stress Reduction on Post-traumatic Stress Disorder Symptoms and Brain Response to Traumatic Reminders of Combat in Operation Enduring Freedom/Operation Iraqi Freedom Combat Veterans with Post-traumatic Stress Disorder.Frontiers in Psychiatry.  8:157. 2017
    2016 An open label pilot study of adjunctive asenapine for the treatment of posttraumatic stress disorderPsychopharmacology bulletin.  46:8-17. 2016
    2016 What I have changed my mind about and why.European Journal of Psychotraumatology.  7:33768. 2016
    2014 Living will status and desire for living will help among rural Alabama veteransResearch in Nursing and Health.  37:379-390. 2014
    2014 Examining the utility of using genotype and functional biology in a clinical pharmacology trial: pilot testing dopamine β-hydroxylase, norepinephrine, and post-traumatic stress disorder.Psychiatric Genetics.  24:181-182. 2014
    2014 Alabama Veterans Rural Health Initiative: a pilot study of enhanced community outreach in rural areasJournal of Rural Health.  30:153-163. 2014
    2014 Alabama Veterans Rural Health Initiative: a pilot study of enhanced community outreach in rural areasJournal of Rural Health.  30:153-163. 2014
    2014 Development of the primary care quality-homeless (PCQ-H) instrument: A practical survey of homeless patients' experiences in primary careMedical Care.  52:734-742. 2014
    2014 Impact of social challenges on gaining employment for veterans with posttraumatic stress disorder: An exploratory moderator analysisPsychiatric Rehabilitation Journal.  37:107-109. 2014
    2013 Comparing homeless persons' care experiences in tailored versus nontailored primary care programsAmerican Journal of Public Health.  103. 2013
    2013 Internet connectivity among rural alabama veterans: Baseline findings from the alabama veterans rural health initiative projectRural and Remote Health.  13. 2013
    2012 A randomized controlled trial of supported employment among veterans with posttraumatic stress disorderPsychiatric Services.  63:464-470. 2012
    2012 Internet connectivity among rural Alabama veterans: Baseline findings from the Alabama Veterans Rural Health Initiative ProjectRural and Remote Health.  12. 2012
    2011 Alabama Veterans Rural Health Initiative: A preliminary evaluation of Unmet Health Care Needs 2011
    2010 Indicators of pretreatment suicidal ideation in adults with major depressive disorderActa Psychiatrica Scandinavica.  121:480-484. 2010
    2010 Does comorbid substance use disorder impair recovery from major depression with SSRI treatment? An analysis of the STAR*D level one treatment outcomesDrug and Alcohol Dependence.  107:161-170. 2010
    2009 Effectiveness study of venlafaxine-XR combined with aripiprazole for chronic or recurrent major depressive disorderAustralian and New Zealand Journal of Psychiatry.  43:956-967. 2009
    2009 Family history of depression and therapeutic outcome: Findings from STAR*DJournal of Clinical Psychiatry.  70:185-195. 2009
    2009 Concurrent anxiety and substance use disorders among outpatients with major depression: Clinical features and effect on treatment outcomeDrug and Alcohol Dependence.  99:248-260. 2009
    2008 Selecting among second-step antidepressant medication monotherapies: Predictive value of clinical, demographic, or first-step treatment featuresArchives of General Psychiatry.  65:870-881. 2008
    2008 Divalproex in the treatment of posttraumatic stress disorder: A randomized, double-blind, placebo-controlled trial in a veteran populationJournal of Clinical Psychopharmacology.  28:84-88. 2008
    2008 A placebo-controlled trial of guanfacine for the treatment of posttraumatic stress disorder in veterans.Psychopharmacology bulletin.  41:8-18. 2008
    2008 Clinical and pharmacoeconomic evaluation of switch to olanzapine in veterans with schizophrenia or schizoaffective disorder.Psychopharmacology bulletin.  41:85-98. 2008
    2008 Major depression and comorbid substance use disordersCurrent Opinion in Psychiatry.  21:14-18. 2008
    2007 Pain in depression: STAR*D study findingsJournal of Psychosomatic Research.  63:113-122. 2007
    2007 Lithium Regulates Glycogen Synthase Kinase-3β in Human Peripheral Blood Mononuclear Cells: Implication in the Treatment of Bipolar DisorderBiological Psychiatry.  61:216-222. 2007
    2007 A pharmacokinetic and clinical evaluation of switching patients with bipolar I disorder from delayed-release to extended-release divalproexJournal of Clinical Psychiatry.  68:1546-1551. 2007
    2007 Are depressed outpatients with and without a family history of substance use disorder different? A baseline analysis of the STAR*D cohortJournal of Clinical Psychiatry.  68:1931-1938. 2007
    2006 Substance use disorder comorbidity in major depressive disorder: A confirmatory analysis of the STAR*D cohortAmerican Journal on Addictions.  15:278-285. 2006
    2006 Long-term pharmacotherapy for post-traumatic stress disorderCNS Drugs.  20:465-476. 2006
    2006 Enrolling research subjects from clinical practice: Ethical and procedural issues in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trialPsychiatry Research.  141:193-200. 2006
    2006 Treatment of chronic posttraumatic stress disorder in combat veterans with citalopram: An open trialJournal of Clinical Psychopharmacology.  26:84-88. 2006
    2005 Divalproex for the treatment of posttraumatic stress disorder: A retrospective chart reviewInternational Journal of Psychiatry in Clinical Practice.  9:278-283. 2005
    2005 Substance use disorder comorbidity in major depressive disorder: An exploratory analysis of the Sequenced Treatment Alternatives to Relieve Depression cohortComprehensive Psychiatry.  46:81-89. 2005
    2004 Clonazepam for treatment of sleep disturbances associated with combat-related posttraumatic stress disorderAnnals of Pharmacotherapy.  38:1395-1399. 2004
    2004 A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: A preliminary studyJournal of Clinical Psychopharmacology.  24:291-297. 2004
    2004 Divalproex sodium in the treatment of adults with bipolar disorderExpert Review of Neurotherapeutics: a key contribution to decision making in the treatment of neurologic and neuropsychiatric disorders.  4:349-362. 2004
    2000 Nefazodone treatment for chronic posttraumatic stress disorder: An open trialJournal of Clinical Psychopharmacology.  20:159-164. 2000
    1999 D-fenfluramine challenge in posttraumatic stress disorderBiological Psychiatry.  45:928-930. 1999

    Research Overview

  • Since 1993, Dr. Davis has had consecutive peer-reviewed funding from the VA Merit, VA Rehabilitation R&D, Department of Defense and National Institute of Mental Health (NIMH), as well as investigator-initiated grants from pharmaceutical industry sources. For nearly a decade, Dr. Davis was Regional Site Director for the NIMH-funded study “Sequenced Treatment Alternatives to Relieve Depression (STAR*D)” and the subsequent Depression Trials Network. Her current research interests include the neurobiology, pharmacological and complementary alternative treatments, and vocational rehabilitation of posttraumatic stress disorder. Currently, she is Study Chair for the VA Cooperative Study Program (CSP#589) entitled “Veterans Individual Placement and Support Towards Advancing Recovery” (VIP-STAR), which is a multisite randomized controlled trial evaluating the efficacy of Individual Placement and Support supported employment in the vocational rehabilitation of unemployed Veterans with posttraumatic stress disorder (PTSD). In addition, Dr. Davis has recently completed a three-site randomized controlled trial of Mindfulness Based Stress Reduction (MBSR) meditation for the treatment of PTSD. She has been involved with numerous industry-sponsored treatment trials in mood and anxiety disorders.
  • Teaching Overview

  • Dr. Davis teaches medical students, psychiatry and family medicine residents, and public psychiatry fellows. She served as a member of the American Psychiatric Association Mood Disorders Workgroup on DSM-5 Revisions. She is a member of the 2017 VA-DoD workgroup for the revision of the Clinical Practice Guidelines for PTSD.
  • Education And Training

    Full Name

  • Lori Davis