Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Inflammation biomarkers and incident coronary heart disease: the Reasons for Geographic And Racial Differences in Stroke StudyAmerican Heart Journal.  253:39-47. 2022
2021 Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure lociMolecular Psychiatry.  26:2111-2125. 2021
2021 Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American IndividualsJAMA Network Open.  4:e2030435. 2021
2021 Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African AmericansEpigenetics.  16:862-875. 2021
2021 Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortiumEBioMedicine.  63. 2021
2020 Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular diseaseNature Communications.  11. 2020
2020 Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (Nature Communications, (2018), 9, 1, (2606), 10.1038/s41467-018-04668-w)Nature Communications.  11. 2020
2020 Carbohydrate and fat intake associated with risk of metabolic diseases through epigenetics of CPT1AAmerican Journal of Clinical Nutrition.  112:1200-1211. 2020
2020 Genetic-based hypertension subtype identification using informative SNPsGenes.  11:1-13. 2020
2020 Inherited causes of clonal haematopoiesis in 97,691 whole genomesNature.  586:763-768. 2020
2020 Genome-Wide association meta-Analysis of individuals of european ancestry identifies suggestive loci for sodium intake, potassium intake, and their ratio measured from 24-Hour or half-Day urine samples 2020
2020 Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scaleNature Genetics.  52:969-983. 2020
2020 Transitions to family caregiving: enrolling incident caregivers and matched non-caregiving controls from a population-based studyAging Clinical and Experimental Research.  32:1829-1838. 2020
2020 A lipidome-wide association study of the lipoprotein insulin resistance indexLipids in Health and Disease.  19:153. 2020
2020 Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome-wide analysis in African AmericansJournal of Thrombosis and Haemostasis.  18:1335-1347. 2020
2020 Gout is associated with an increased risk for incident heart failure among older adults: The REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort studyArthritis Research and Therapy.  22. 2020
2020 APOL1 Nephropathy Risk Alleles and Mortality in African American Adults: A Cohort StudyAmerican Journal of Kidney Diseases.  75:54-60. 2020
2020 Cardiovascular Health and Transition from Controlled Blood Pressure to Apparent Treatment Resistant Hypertension: The Jackson Heart Study and the REGARDS StudyHypertension.  1953-1961. 2020
2020 Severity of Hypertension Mediates the Association of Hyperuricemia With Stroke in the REGARDS Case Cohort StudyHypertension.  75:246-256. 2020
2020 Soluble cd14, ischemic stroke, and coronary heart disease risk in a prospective study: The regards cohortJournal of the American Heart Association.  9. 2020
2019 Apol1 nephropathy risk alleles and risk of sepsis in blacksClinical Journal of the American Society of Nephrology.  14:1733-1740. 2019
2019 Gain of function in somatic TP53 mutations is associated with immune-rich breast tumors and changes in tumor-associated macrophagesMolecular Genetics and Genomic Medicine.  7. 2019
2019 Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working GroupAmerican Journal of Hypertension.  32:1146-1153. 2019
2019 Does the association of diabetes with stroke risk differ by age, race, and sex? Results from the reasons for geographic and racial differences in stroke (REGARDS) studyDiabetes reviews (Alexandria, Va.).  42:1966-1972. 2019
2019 Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African AmericansMolecular Genetics and Genomic Medicine.  7. 2019
2019 Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals.Hypertension.  74:614-622. 2019
2019 Integrating hypertension phenotype and genotype with hybrid non-negative matrix factorization.Bioinformatics.  35:2885. 2019
2019 A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressureHuman Molecular Genetics.  28:2615-2633. 2019
2019 Association of sickle cell trait with atrial fibrillation: The REGARDS cohortJournal of Electrocardiology.  55:1-5. 2019
2019 Sickle cell trait and risk of cognitive impairment in African-Americans: The REGARDS cohortEClinicalMedicine.  11:27-33. 2019
2019 Integrating hypertension phenotype and genotype with hybrid non-negative matrix factorizationBioinformatics.  35:1395-1403. 2019
2019 Distracted Driving and Risk of Crash or Near-Crash Involvement among Older Drivers Using Naturalistic Driving Data with a Case-Crossover Study Design 2019
2019 Systematic Error Removal Using Random Forest for Normalizing Large-Scale Untargeted Lipidomics DataAnalytical Chemistry.  91:3590-3596. 2019
2019 Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization studyNeurology.  92:E944-E950. 2019
2019 Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing dataHuman Genetics.  138:199-210. 2019
2019 Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry 2019
2019 A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS studyBMC Medical Genomics.  12. 2019
2019 Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic TraitsAmerican Journal of Human Genetics.  104:112-138. 2019
2019 APOL1 kidney risk variants and cardiovascular disease: An individual participant data meta-analysisJournal of the American Society of Nephrology.  30:2027-2036. 2019
2019 An exome-wide sequencing study of the GOLDN cohort reveals novel associations of coding variants and fasting plasma lipidsFrontiers in Genetics.  10. 2019
2019 Clinical correlates and heritability of cardiac mechanics: The HyperGEN studyInternational Journal of Cardiology.  274:208-213. 2019
2019 Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populationsPLoS Genetics.  15. 2019
2018 Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestriesNature Communications.  9. 2018
2018 Deep-coverage whole genome sequences and blood lipids among 16,324 individualsNature Communications.  9. 2018
2018 Erratum to: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (Nature Communications, (2018), 9, 1, (2606), 10.1038/s41467-018-04668-w)Nature Communications.  9. 2018
2018 GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomesNature Communications.  9. 2018
2018 Association of sickle cell trait with ischemic stroke among African americans a meta-analysisJAMA Neurology.  75:802-807. 2018
2018 West African ancestry and nocturnal blood pressure in African Americans: The Jackson Heart StudyAmerican Journal of Hypertension.  31:706-714. 2018
2018 Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN studyClinical Epigenetics.  10. 2018
2018 Epigenome-wide association study of metabolic syndrome in African-American adultsClinical Epigenetics.  10. 2018
2018 Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypesNature Genetics.  50:524-537. 2018
2018 Publisher correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes(Nature Genetics, (2018) 50, 4, (524-537), 10.1038/s41588-018-0058-3)Nature Genetics.  51:1192-1193. 2018
2018 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood PressureAmerican Journal of Human Genetics.  102:375-400. 2018
2018 General cognitive impairment as a risk factor for motor vehicle collision involvement: A prospective population-based studyGeriatrics.  3. 2018
2018 PCSK9 variants, low-density lipoprotein cholesterol, and neurocognitive impairment reasons for geographic and racial differences in stroke study (REGARDS)Circulation.  137:1260-1269. 2018
2018 The association of nocturnal hypertension and nondipping blood pressure with treatment-resistant hypertension: The Jackson Heart StudyJournal of the CardioMetabolic Syndrome.  20:438-446. 2018
2018 Trans-ethnic analysis of metabochip data identifies two new loci associated with BMIInternational Journal of Obesity.  42:384-390. 2018
2018 A DNA methylation biomarker of alcohol consumptionMolecular Psychiatry.  23:422-433. 2018
2018 APOL1, CDKN2A/CDKN2B, and HDAC9 polymorphisms and small vessel ischemic strokeActa Neurologica Scandinavica.  137:133-141. 2018
2018 An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohortJournal of Lipid Research.  59:722-729. 2018
2017 DNA Methylation Analysis Identifies Loci for Blood Pressure RegulationAmerican Journal of Human Genetics.  101:888-902. 2017
2017 Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunitiesJournal of the Neurological Sciences.  382:18-28. 2017
2017 Chronic kidney disease and incident apparent treatment-resistant hypertension among blacks: Data from the Jackson Heart StudyJournal of the CardioMetabolic Syndrome.  19:1117-1124. 2017
2017 Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage 2017
2017 An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet NetworkPharmacogenomics.  18:1333-1341. 2017
2017 Interleukin–6 (IL-6) rs1800796 and cyclin dependent kinase inhibitor (CDKN2A/CDKN2B) rs2383207 are associated with ischemic stroke in indigenous West African MenJournal of the Neurological Sciences.  379:229-235. 2017
2017 Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function: From the HyperGEN Study.Journal of the American College of Cardiology.  70:715-724. 2017
2017 PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data from 9 Studies of Blacks and WhitesCirculation: Cardiovascular Genetics.  10. 2017
2017 Influence of common and rare genetic variation on warfarin dose among African-Americans and European-Americans using the exome arrayPharmacogenomics.  18:1059-1073. 2017
2017 Sickle cell trait and the risk of ESRD in blacksJournal of the American Society of Nephrology.  28:2180-2187. 2017
2017 Genetics of Blood Pressure: New Insights Into a Complex TraitAmerican Journal of Kidney Diseases.  69:723-725. 2017
2017 Genome- and CD4+ T-cell methylome-wide association study of circulating trimethylamine-N-oxide in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) 2017
2017 Phenomapping for the Identification of Hypertensive Patients with the Myocardial Substrate for Heart Failure with Preserved Ejection FractionJournal of Cardiovascular Translational Research.  10:275-284. 2017
2017 Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established lociHuman Genetics.  136:771-800. 2017
2017 Visual sensory and visual-cognitive function and rate of crash and near-crash involvement among older drivers using naturalistic driving data 2017
2017 Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and functionJournal of Clinical Investigation.  127:1798-1812. 2017
2017 Admixture Mapping of Subclinical Atherosclerosis and Subsequent Clinical Events among African Americans in 2 Large Cohort StudiesCirculation: Cardiovascular Genetics.  10. 2017
2017 Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortiumPLoS Genetics.  13. 2017
2017 National patterns in intensity and frequency of outpatient care for apparent treatment-resistant hypertensionAmerican Heart Journal.  186:29-39. 2017
2017 CPT1A methylation is associated with plasma adiponectin 2017
2017 Epigenetic Patterns in Blood Associated with Lipid Traits Predict Incident Coronary Heart Disease Events and Are Enriched for Results from Genome-Wide Association StudiesCirculation: Cardiovascular Genetics.  10. 2017
2017 Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populationsInternational Journal of Obesity.  41:324-331. 2017
2017 Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization ApproachPLoS Medicine.  14. 2017
2017 D-dimer in african americans whole genome sequence analysis and relationship to cardiovascular disease risk in the Jackson Heart Study 2017
2017 Local ancestry and clinical cardiovascular events among African Americans from the atherosclerosis risk in communities studyJournal of the American Heart Association.  6. 2017
2017 Whole exome analyses to examine the impact of rare variants on left ventricular traits in African American participants from the HyperGEN and GENOA studies. 2017
2016 Hemostasis biomarkers and risk of sepsis: the REGARDS cohortJournal of Thrombosis and Haemostasis.  14:2169-2176. 2016
2016 Epigenetic Signatures of Cigarette SmokingCirculation: Cardiovascular Genetics.  9:436-447. 2016
2016 Epigenetics of Lipid PhenotypesCurrent Cardiovascular Risk Reports.  10. 2016
2016 Heritable DNA methylation in CD4+ Cells among complex families displays genetic and non-genetic effectsPLoS One.  11. 2016
2016 The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT studyJournal of Human Hypertension.  30:549-554. 2016
2016 Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell TraitsAmerican Journal of Human Genetics.  99:8-21. 2016
2016 Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and InsulinAmerican Journal of Human Genetics.  99:56-75. 2016
2016 Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart StudyBone.  87:71-77. 2016
2016 Association of Central Adiposity with Adverse Cardiac Mechanics; Findings from the Hypertension Genetic Epidemiology Network StudyCirculation: Cardiovascular Imaging.  9. 2016
2016 APOL1 nephropathy risk variants are associated with altered high-density lipoprotein profiles in African AmericansNephrology Dialysis Transplantation.  31:602-608. 2016
2016 Archeological Echocardiography: Digitization and Speckle Tracking Analysis of Archival Echocardiograms in the HyperGEN Study 2016
2016 Driving with pets and motor vehicle collision involvement among older drivers: A prospective population-based studyAccident Analysis and Prevention.  88:169-174. 2016
2016 Interaction of methylation-related genetic variants with circulating fatty acids on plasma lipids: A meta-analysis of 7 studies and methylation analysis of 3 studies in the Cohorts for Heart and Aging Research in Genomic Epidemiology consortiumAmerican Journal of Clinical Nutrition.  103:567-578. 2016
2016 The effects of omega-3 polyunsaturated fatty acids and genetic variants on methylation levels of the interleukin-6 gene promoterMolecular Nutrition and Food Research.  60:410-419. 2016
2016 A genome-wide study of lipid response to fenofibrate in Caucasians: A combined analysis of the GOLDN and ACCORD studiesPharmacogenetics and Genomics.  26:324-333. 2016
2016 Association of DNA methylation at CPT1A locus with metabolic syndrome in the genetics of lipid lowering drugs and diet network (GOLDN) studyPLoS One.  11. 2016
2016 Epigenome-wide association study of triglyceride postprandial responses to a high-fat dietary challengeJournal of Lipid Research.  57:2200-2207. 2016
2015 Drug-gene interactions of antihypertensive medications and risk of incident cardiovascular disease: A pharmacogenomics study from the CHARGE consortiumPLoS One.  10. 2015
2015 A family-specific linkage analysis of blood lipid response to fenofibrate in the Genetics of Lipid Lowering Drug and Diet NetworkPharmacogenetics and Genomics.  25:511-514. 2015
2015 Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated lociHuman Molecular Genetics.  24:4464-4479. 2015
2015 Apparent treatment-resistant hypertension among individuals with history of stroke or transient ischemic attackAmerican Journal of Medicine.  128:707-714.e2. 2015
2015 Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumferenceObesity.  23:1493-1501. 2015
2015 Deep sequencing of RYR3 gene identifies rare and common variants associated with increased carotid intima-media thickness (cIMT) in HIV-infected individualsJournal of Human Genetics.  60:63-67. 2015
2015 Genetic loci associated with circulating phospholipid trans fatty acids: A meta-analysis of genome-wide association studies from the CHARGE consortiumAmerican Journal of Clinical Nutrition.  101:398-406. 2015
2015 Genetic variants modify the effect of age on APOE methylation in the genetics of lipid lowering drugs and diet network studyAging Cell.  14:49-59. 2015
2015 Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN studyFrontiers in Genetics.  6. 2015
2015 PCSK9 variation and association with blood pressure in African Americans: Preliminary findings from the HyperGEN and REGARDS studiesFrontiers in Genetics.  6. 2015
2014 Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT studyPharmacogenetics and Genomics.  24:556-563. 2014
2014 Diastolic wall strain: A simple marker of abnormal cardiac mechanicsCardiovascular Ultrasound.  12. 2014
2014 Multi-ethnic fine-mapping of 14 central adiposity loci.Human Molecular Genetics.  23:4738-4744. 2014
2014 Epigenome-wide association study of fasting blood lipids in the genetics of lipid-lowering drugs and diet network studyCirculation.  130:565-572. 2014
2014 Genomics of post-prandial lipidomic phenotypes in the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) studyPLoS One.  9. 2014
2014 Determination of prevalence, risk factors, and comorbidities in a large, population-based cohortHypertension.  63:451-458. 2014
2014 CPT1A: The future of heart disease detection and personalized medicine?Clinical Lipidology.  9:9-12. 2014
2014 Epigenome-wide association study of fasting measures of glucose, insulin, and homa-ir in the genetics of lipid lowering drugs and diet network studyDiabetes.  63:801-807. 2014
2014 HIV, inflammation, and calcium in atherosclerosis 2014
2014 Apparent treatment-resistant hypertension and risk for stroke, coronary heart disease, and all-cause mortalityJournal of the American Society of Hypertension.  8:405-413. 2014
2014 Association of comorbidity burden with abnormal cardiac mechanics: Findings from the HyperGEN studyJournal of the American Heart Association.  3. 2014
2014 Association of low-grade albuminuria with adverse cardiac mechanics: Findings from the hypertension genetic epidemiology network (hypergen) studyCirculation.  129:42-50. 2014
2014 Healthy lifestyle factors and risk of cardiovascular events and mortality in treatment-resistant hypertension: The Reasons for Geographic and Racial Differences in Stroke studyHypertension.  64:465-471. 2014
2014 Incident ESRD and treatment-resistant hypertension: The reasons for geographic and racial differences in stroke (REGARDS) studyAmerican Journal of Kidney Diseases.  63:781-788. 2014
2014 RYR3 gene variants in subclinical atherosclerosis among HIV-infected women in the Women's Interagency HIV Study (WIHS)Atherosclerosis.  233:666-672. 2014
2014 Response to should more significance be granted to medication response to antihypertensives in patients with resistant hypertension?Hypertension.  63. 2014
2014 The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study.Frontiers in Pharmacology.  5:210. 2014
2013 Genetic and adverse health outcome associations with treatment resistant hypertension in GenHATInternational Journal of Hypertension.  2013. 2013
2013 Fine mapping and identification of BMI loci in African AmericansAmerican Journal of Human Genetics.  93:661-671. 2013
2013 Prevalence of apparent treatment-resistant hypertension among individuals with CKDClinical Journal of the American Society of Nephrology.  8:1583-1590. 2013
2013 Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New LociPLoS Genetics.  9. 2013
2013 RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment 2013
2013 A431: Epigenetics of Fasting Insulin and Glucose ConcentrationsDiabetes.  62:A431-A431. 2013
2013 A meta-analysis identifies new loci associated with body mass index in individuals of African ancestryNature Genetics.  45:690-696. 2013
2013 Pharmacogenomics of high-density lipoprotein-cholesterol-raising therapiesExpert Review of Cardiovascular Therapy.  11:355-364. 2013
2013 A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) StudyPLoS Genetics.  9. 2013
2013 Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network 2013
2013 SNPs located at CpG sites modulate genome-epigenome interactionEpigenetics.  8:802-806. 2013
2012 Whole-exome sequencing and an iPSC-derived cardiomyocyte model provides a powerful platform for gene discovery in left ventricular hypertrophyFrontiers in Genetics.  3. 2012
2012 Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to FenofibratePLoS One.  7. 2012
2012 Prevalence and Correlates of Low Medication Adherence in Apparent Treatment-Resistant HypertensionJournal of the CardioMetabolic Syndrome.  14:694-700. 2012
2012 Rare PPARA variants and extreme response to fenofibrate in the Genetics of Lipid-Lowering Drugs and Diet Network StudyPharmacogenetics and Genomics.  22:367-372. 2012
2011 A data-driven method for identifying rare variants with heterogeneous trait effectsGenetic Epidemiology.  35:679-685. 2011
2011 Genome-wide detection of allele specific copy number variation associated with insulin resistance in african americans from the hyperGEN studyPLoS One.  6. 2011
2011 Response to letter regarding article, "Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the GOLDN study"Circulation: Cardiovascular Genetics.  4. 2011
2011 Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected menPharmacogenetics and Genomics.  21:798-807. 2011
2010 Apolipoprotein e polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the genetics of lipid lowering and diet network (GOLDN) studyCirculation: Cardiovascular Genetics.  3:462-467. 2010
2010 A genome-wide association study of carotid atherosclerosis in HIV-infected menAIDS.  24:583-592. 2010
2010 Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT StudyJournal of Hypertension.  28:2076-2083. 2010
2008 Barriers to genetic testing among persons at risk for alpha-1 antitrypsin deficiencyGenetic Testing and Molecular Biomarkers.  12:501-505. 2008
2008 A genomic scan for age at onset of Alzheimer's disease in 437 families from the NIMH genetic initiativeAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  147:784-792. 2008
2007 Does genetic testing result in behavioral health change? Changes in smoking behavior following testing for alpha-1 antitrypsin deficiencyAnnals of Behavioral Medicine.  33:22-28. 2007
2005 Association studies of transforming growth factor-β1 and Alzheimer's diseaseAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  139 B:38-41. 2005
2005 Delay in diagnosis of alpha1-antitrypsin deficiency: a continuing problem.Chest.  128:1989-1994. 2005
2004 Genetic testing for alpha1-antitrypsin deficiency.Genetics in Medicine.  6:204-210. 2004
2001 Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cells 2001

Chapter

Year Title Altmetric
2014 Cardiovascular Genetics and Genomics in Clinical Practice. Part 1: Toolbox for Genetics and Genomics: The Basics 2014
2011 Gene-environment Interactions: Gene-environment interactions in human traits 2011
2011 Gene-Environment Interactions in Human Traits.  855-862. 2011

Principal Investigator On

  • A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits  awarded by Washington University
  • Cardiorenal Genomics for Risk Prediction in African Descent Populations  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Characterizing Pleitropy in Cardiometabolic Phenotypes Among Diverse Populations  awarded by University of North Carolina at Chapel Hill
  • Determinants, Trajectories, and Consequences of Abnormal Cardiac Mechanics  awarded by Northwestern University
  • Epigenetic Determinants of Left Ventricular Structure and Function in Hypertensive African Americans  awarded by University of Kentucky
  • Genetic Underpinnings of Cardiorenal risk in Africans and African Americans  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genetic and Epigenetic Risk Scores for Chronic Kidney Disease in African Americans  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by University of Kentucky
  • Genomic Background of Blood Pressure Response to Thiazide Diuretic in African Americans  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genomics of Lipidomic Phenotypes in a Postprandial Intervention Dietary Study  awarded by American Heart Association
  • How Inflammation and High Density Lipoproteins Affect the Relationship Between APOL 1 and Outcomes  awarded by American Heart Association
  • HyperGEN: Genetics of Left Ventricular Hypertrophy  awarded by University of Kentucky
  • Identification of the Role of HDL Function in Human Cardiovascular Disease through Proteomics and Genetics  awarded by Oregon Health & Science University
  • Metabolic Predictors of Stroke in REGARDS  awarded by MASSACHUSETTS GENERAL HOSPITAL
  • Prospective Meta-Analyses of Drug-gene Interactions: CHARGE GWAS  awarded by UNIVERSITY OF WASHINGTON
  • Trace Mineral Levels, The Trajectory of Cognitive Decline and Telomere Attrition  awarded by Columbia University
  • Trace Mineral Levels, the Trajectory of Cognitive Decline and Telomere Attrition  awarded by Indiana University
  • UAB Center for AIDS Research - Lipidomic Profiling in HIV Patients Newly Initiating Antiretroviral Treatment  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Investigator On

  • Determining True Versus Apparent Treatment-Resistant Hypertension among African Americans in the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Determining True Versus Apparent Treatment-resistant Hypertension Among African Americans in the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Early Life Stress, DNA Methylation, and Health Disparities Across Ages  awarded by NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH DISPARITIES/NIH/DHHS
  • Epigenetic Biomarkers of Preeclampsia Risk Among Mothers with Chronic Hypertension  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Epigenetic Regulation of Lipids in Response to Dietary Fat and Fenofibrate  awarded by University of Kentucky
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Genomewide Association Study of Lipid Response to Fenofibrate and Dietary Fat  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • HyperGEN: Genetics of Left Ventricular Hypertrophy  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Hypergen: Genetics of Left Ventricular Hypertrophy  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Incorporation of a Hypertension Working Group into the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Incorporation of a Hypertension Working Group into the Jackson Heart Study  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Integrating Genomic Risk Assessment for Chronic Disease Management in a Diverse Population  awarded by National Human Genome Research Institute/NIH/DHHS
  • Kidney Undergraduate Research Experience (KURE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • PRedOctoral Phd and MD Research Training In TEams (PROmoTE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • PRedoctoral Interdisciplinary Training in Renal Physiology and MEdIcIne (PRIME)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Predictors of Hemorrhage Among Patients on Direct Acting Oral Anticoagulants  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Prospective Meta-Analyses of Drug-Gene Interactions: CHARGE GWAS Consortium  awarded by UNIVERSITY OF WASHINGTON
  • Stroke Investigative Research & Educational Network  awarded by UNIVERSITY OF IBADAN
  • Transitions to Family Caregiving and Its Impact on Health Indicators  awarded by Johns Hopkins University
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Use of High Density Lipoprotein Proteome in the Prediction of Cognitive Impairment and Alzheimer’s Disease (REGARDS)  awarded by Mount Sinai School of Medicine ^
  • VCID and Stroke in Bi-Racial National Cohort  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • VCID and Stroke in a Bi-racial National Cohort  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Teaching Activities

  • EPI697 - Internship (Spring Term 2018)
  • EPI697 - Internship (Spring Term 2020)
  • EPI697 - Internship (Summer Term 2014)
  • EPI697 - Internship (Summer Term 2015)
  • EPI697 - Internship (Summer Term 2016)
  • EPI697 - Internship (Summer Term 2017)
  • EPI697 - Internship (Summer Term 2018)
  • EPI697 - Internship (Summer Term 2020)
  • EPI697 - Internship (Summer Term 2021)
  • EPI698 - Directed Research (Fall Term 2015)
  • EPI698 - Directed Research (Spring Term 2020)
  • EPI698 - Directed Research (Spring Term 2021)
  • EPI698 - Directed Research (Spring Term 2023)
  • EPI699 - Project Research (Fall Term 2017)
  • EPI699 - Project Research (Summer Term 2016)
  • EPI699 - Project Research (Summer Term 2017)
  • EPI710 - Analysis Case Control Studies (Spring Term 2015)
  • EPI710 - Analysis Case Control Studies (Spring Term 2016)
  • EPI710 - Analysis Case Control Studies (Spring Term 2017)
  • EPI710 - Analysis Case Control Studies (Spring Term 2018)
  • EPI710 - Analysis Case Control Studies (Spring Term 2019)
  • EPI710 - Analysis Case Control Studies (Spring Term 2020)
  • EPI710 - Analysis Case Control Studies (Spring Term 2021)
  • EPI710 - Analysis Case Control Studies (Spring Term 2022)
  • EPI710 - Analysis Case Control Studies (Spring Term 2023)
  • EPI798 - Doctoral Directed Research (Fall Term 2014)
  • EPI798 - Doctoral Directed Research (Fall Term 2015)
  • EPI798 - Doctoral Directed Research (Fall Term 2017)
  • EPI798 - Doctoral Directed Research (Fall Term 2018)
  • EPI798 - Doctoral Directed Research (Fall Term 2020)
  • EPI798 - Doctoral Directed Research (Fall Term 2021)
  • EPI798 - Doctoral Directed Research (Spring Term 2013)
  • EPI798 - Doctoral Directed Research (Spring Term 2015)
  • EPI798 - Doctoral Directed Research (Spring Term 2016)
  • EPI798 - Doctoral Directed Research (Spring Term 2018)
  • EPI798 - Doctoral Directed Research (Spring Term 2019)
  • EPI798 - Doctoral Directed Research (Spring Term 2020)
  • EPI798 - Doctoral Directed Research (Spring Term 2021)
  • EPI798 - Doctoral Directed Research (Spring Term 2022)
  • EPI798 - Doctoral Directed Research (Spring Term 2023)
  • EPI798 - Doctoral Directed Research (Summer Term 2014)
  • EPI798 - Doctoral Directed Research (Summer Term 2015)
  • EPI798 - Doctoral Directed Research (Summer Term 2018)
  • EPI798 - Doctoral Directed Research (Summer Term 2020)
  • EPI798 - Doctoral Directed Research (Summer Term 2021)
  • EPI798 - Doctoral Directed Research (Summer Term 2022)
  • EPI799 - Dissertation Research (Fall Term 2016)
  • EPI799 - Dissertation Research (Fall Term 2019)
  • EPI799 - Dissertation Research (Fall Term 2020)
  • EPI799 - Dissertation Research (Fall Term 2022)
  • EPI799 - Dissertation Research (Spring Term 2017)
  • EPI799 - Dissertation Research (Spring Term 2020)
  • EPI799 - Dissertation Research (Spring Term 2021)
  • EPI799 - Dissertation Research (Spring Term 2023)
  • EPI799 - Dissertation Research (Summer Term 2016)
  • EPI799 - Dissertation Research (Summer Term 2019)
  • EPI799 - Dissertation Research (Summer Term 2020)
  • EPI799 - Dissertation Research (Summer Term 2021)
  • Education And Training

  • Doctor of Philosophy in Epidemiology, University of Alabama at Birmingham 2008
  • Master of Science in Health and Medical Biostatistics, Medical University of South Carolina 2004
  • Bachelor of Science or Mathematics in Biology, University of North Carolina System : Chapel Hill 1999
  • Full Name

  • Marguerite Irvin