| Year |
Title |
Altmetric |
| 2022
|
Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.
Journal of Medicinal Chemistry.
65:14409-14423.
2022
|
|
| 2021
|
Hemolytic activity and biofilm-formation among clinical isolates of group B streptococcus causing acute urinary tract infection and asymptomatic bacteriuria.
International Journal of Medical Microbiology.
311.
2021
|
|
| 2021
|
Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase (GAPDH) elicits multiple cytokines from human cells and has a minor effect on bacterial persistence in the murine female reproductive tract.
Virulence.
12:3015-3027.
2021
|
|
| 2020
|
Chlamydia trachomatis glyceraldehyde 3-phosphate dehydrogenase: Enzyme kinetics, high-resolution crystal structure, and plasminogen binding.
Protein Science.
29:2446-2458.
2020
|
|
| 2020
|
Novel structure of the N-terminal helical domain of BibA, a group B streptococcus Immunogenic bacterial adhesin.
Acta crystallographica. Section D, Structural biology.
76:759-770.
2020
|
|
| 2020
|
A simple and reliable method for determination of optimum pH in coupled enzyme assays.
BioTechniques: the journal of laboratory technology for bioresearch.
68:200-203.
2020
|
|
| 2019
|
An Updated Conceptual Model on the Pathogenesis of Bacterial Vaginosis.
Journal of Infectious Diseases.
220:1399-1405.
2019
|
|
| 2019
|
An overview of structure, function, and regulation of pyruvate kinases.
Protein Science.
28:1771-1784.
2019
|
|
| 2019
|
Crystal structure of the N-terminal domain of the fibronectin-binding protein PavA from Streptococcus pneumoniae.
Acta Crystallographica Section F: Structural Biology Communications.
75:657-662.
2019
|
|
| 2019
|
Mosquito bite-induced controlled human malaria infection with Plasmodium vivax or P. Falciparum generates immune responses to homologous and heterologous preerythrocytic and erythrocytic antigens.
Infection and Immunity.
87.
2019
|
|
| 2019
|
Rapid bladder interleukin-10 synthesis in response to uropathogenic Escherichia coli is part of a defense strategy triggered by the major bacterial flagellar filament fliC and contingent on TLR5.
mSphere.
4.
2019
|
|
| 2016
|
Poxvirus uracil-DNA glycosylase—An unusual member of the family I uracil-DNA glycosylases.
Protein Science.
25:2113-2131.
2016
|
|
| 2016
|
Small molecule inhibition of the ubiquitin-specific protease USP2 accelerates cyclin D1 degradation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma models.
Journal of Biological Chemistry.
291:24628-24640.
2016
|
|
| 2016
|
Crystal structures of group B streptococcus glyceraldehyde-3-phosphate dehydrogenase: Apo-form, binary and ternary complexes.
PLoS One.
11.
2016
|
|
| 2016
|
Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.
Biochemical Pharmacology.
109:14-26.
2016
|
|
| 2016
|
Uropathogenic Escherichia coli engages CD14-dependent signaling to enable bladder-macrophage-dependent control of acute urinary tract infection.
Journal of Infectious Diseases.
213:659-668.
2016
|
|
| 2015
|
Binding of undamaged double stranded DNA to vaccinia virus uracil-DNA Glycosylase.
BMC Structural Biology.
15.
2015
|
|
| 2015
|
Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase.
International Journal of Biological Macromolecules.
74:608-619.
2015
|
|
| 2014
|
Uracil-DNA glycosylases - Structural and functional perspectives on an essential family of DNA repair enzymes.
Protein Science.
23:1667-1685.
2014
|
|
| 2014
|
Structure of Streptococcus agalactiae glyceraldehyde-3-phosphate dehydrogenase holoenzyme reveals a novel surface.
Acta Crystallographica Section F: Structural Biology Communications.
70:1333-1339.
2014
|
|
| 2013
|
Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications Online.
69:1328-1334.
2013
|
|
| 2013
|
Crystallization and preliminary X-ray diffraction analysis of three recombinant mutants of Vaccinia virus uracil DNA glycosylase.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications Online.
69:295-301.
2013
|
|
| 2012
|
Crystal Structure of Cryptosporidium parvum Pyruvate Kinase.
PLoS One.
7.
2012
|
|
| 2011
|
Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for development of antiviral agents.
Antimicrobial Agents and Chemotherapy.
55:5054-5062.
2011
|
|
| 2011
|
Structure of the catalytic domain of Plasmodium falciparum ARF GTPase-activating protein (ARFGAP).
Acta Crystallographica Section F: Structural Biology and Crystallization Communications Online.
67:1339-1344.
2011
|
|
| 2011
|
Crystal structure of Plasmodium falciparum phosphoglycerate kinase: Evidence for anion binding in the basic patch.
Biochemical and Biophysical Research Communications.
412:203-206.
2011
|
|
| 2011
|
Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.
Journal of Medicinal Chemistry.
54:3260-3267.
2011
|
|
| 2011
|
Malaria immunoepidemiology in low transmission: Correlation of infecting genotype and immune response to domains of Plasmodium falciparum merozoite surface protein 3.
Infection and Immunity.
79:2070-2078.
2011
|
|
| 2011
|
Phylogenetic lineage and pilus protein Spb1/SAN1518 affect opsonin-independent phagocytosis and intracellular survival of Group B Streptococcus.
Microbes and Infection: a journal on infectious agents and host defenses.
13:369-382.
2011
|
|
| 2010
|
Vaccinia virus D4 mutants defective in processive DNA synthesis retain binding to A20 and DNA.
Journal of Virology.
84:12325-12335.
2010
|
|
| 2010
|
Structure of Plasmodium falciparum ADP-ribosylation factor 1.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications Online.
66:1426-1431.
2010
|
|
| 2010
|
Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase.
Bioorganic and Medicinal Chemistry.
18:4056-4066.
2010
|
|
| 2009
|
Structures of dihydrofolate reductase-thymidylate synthase of trypanosoma cruzi in the folate-free state and in complex with two antifolate drugs, trimetrexate and methotrexate.
Acta Crystallographica Section D: Biological Crystallography.
65:704-716.
2009
|
|
| 2009
|
An unexpected phosphate binding site in Glyceraldehyde 3-Phosphate Dehydrogenase: Crystal structures of apo, holo and ternary complex of Cryptosporidium parvum enzyme.
BMC Structural Biology.
9.
2009
|
|
| 2008
|
Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
Proteins: Structure, Function, and Bioinformatics.
73:889-901.
2008
|
|
| 2007
|
Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly.
BMC Structural Biology.
7.
2007
|
|
| 2007
|
Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.
Journal of Molecular Biology.
370:701-713.
2007
|
|
| 2007
|
Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.
Antimicrobial Agents and Chemotherapy.
51:1795-1803.
2007
|
|
| 2007
|
Structures of vaccinia virus dUTPase and its nucleotide complexes.
Acta Crystallographica Section D: Biological Crystallography.
63:571-580.
2007
|
|
| 2006
|
The structure of the Plasmodium falciparum EBA175 ligand domain and the molecular basis of host specificity.
Trends in Parasitology.
22:143-145.
2006
|
|
| 2005
|
Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor.
Journal of Structural Biology.
152:64-75.
2005
|
|
| 2005
|
Lipophilic antifolate trimetrexate is a potent inhibitor of trypanosoma cruzi: Prospect for chemotherapy of chagas' disease.
Antimicrobial Agents and Chemotherapy.
49:3234-3238.
2005
|
|
| 2005
|
Crystallization of three key glycolytic enzymes of the opportunistic pathogen Cryptosporidium parvum.
BBA: Proteins and Proteomics.
1750:166-172.
2005
|
|
| 2004
|
Biochemical characterization and crystallization of recombinant 3-phosphoglycerate kinase of Plasmodium falciparum.
BBA: Proteins and Proteomics.
1699:277-280.
2004
|
|
| 2004
|
Plasmodium falciparum ARFGAP: Expression and crystallization of the catalytic domain.
BBA: Proteins and Proteomics.
1698:127-130.
2004
|
|
| 2003
|
Docking and biological activity of pteridine analogs: Search for inhibitors of pteridine reductase enzymes from Trypanosoma cruzi.
Computational and Theoretical Chemistry.
635:37-44.
2003
|
|
| 2003
|
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.
Journal of Medicinal Chemistry.
46:3865-3876.
2003
|
|
| 2003
|
A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.
Journal of Molecular Biology.
328:131-146.
2003
|
|
| 2003
|
The Plasmodium falciparum family of Rab GTPases.
Gene.
306:13-25.
2003
|
|
| 2003
|
Trypanosoma cruzi genome encodes a pteridine reductase 2 protein.
Molecular and Biochemical Parasitology.
127:89-92.
2003
|
|
| 2002
|
Nonpeptide inhibitors of cathepsin G: Optimization of a novel β-ketophosphonic acid lead by structure-based drug design.
Journal of the American Chemical Society.
124:3810-3811.
2002
|
|
| 2002
|
Crystal structure of human L-isoaspartyl-O-methyltransferase with S-adenosyl homocysteine at 1.6-Å resolution and modeling of an isoaspartyl-containing peptide at the active site.
Protein Science.
11:625-635.
2002
|
|
| 2002
|
Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate.
Biochemical Journal.
361:437-441.
2002
|
|
| 2001
|
Expression, purification, crystallization and preliminary crystallographic analysis of recombinant pteridine reductase of Trypanosoma cruzi.
Acta Crystallographica Section D: Biological Crystallography.
57:1671-1673.
2001
|
|
| 2001
|
Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis.
Acta Crystallographica Section D: Biological Crystallography.
57:806-812.
2001
|
|
| 2001
|
Crystallization and preliminary x-ray diffraction analysis of protein l-isoaspartyl o-methyltransferase from wheat germ.
Acta Crystallographica Section D: Biological Crystallography.
57:304-305.
2001
|
|
| 2000
|
Structure of human α-thrombin complexed with RWJ-51438 at 1.7 Å: Unusual perturbation of the 60A-60I insertion loop.
Acta Crystallographica Section D: Biological Crystallography.
56:1395-1400.
2000
|
|
| 2000
|
Plasmodium falciparum Rab6 GTPase: Expression, purification, crystallization and preliminary crystallographic studies.
Acta Crystallographica Section D: Biological Crystallography.
56:1017-1019.
2000
|
|
| 2000
|
Structure of the nucleotide-binding domain of Plasmodium falciparum Rab6 in the GDP-bound form.
Acta Crystallographica Section D: Biological Crystallography.
56:937-944.
2000
|
|
| 2000
|
Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 Å resolution.
Protein Science.
9:704-712.
2000
|
|
| 2000
|
Toxoplasma gondii adenosine kinase: Expression, purification, characterization, crystallization and preliminary crystallographic analysis.
Acta Crystallographica Section D: Biological Crystallography.
56:76-78.
2000
|
|
| 1999
|
Expression, purification, crystallization and preliminary x-ray diffraction analysis of uracil phosphoribosyltransferase of Toxoplasma gondii.
Acta Crystallographica Section D: Biological Crystallography.
55:347-349.
1999
|
|
| 1999
|
Structural study of Escherichia coli NAD synthetase: Overexpression, purification, crystallization, and preliminary crystallographic analysis.
Journal of Structural Biology.
127:279-282.
1999
|
|
| 1998
|
Large-scale preparation of the Δ10 form of staphylokinase by in vitro processing of recombinant staphylokinase with purified human plasminogen.
Applied Biochemistry and Biotechnology.
69:147-156.
1998
|
|
| 1997
|
Crystal structure of calcium bound domain VI of calpain at 1.9 Å resolution and its role in enzyme assembly, regulation, and inhibitor binding.
Nature Structural and Molecular Biology.
4:539-547.
1997
|
|
| 1997
|
Crystallization and preliminary cryogenic x-ray diffraction analyses of protein L-isoaspartyl O-methyltransferase from human fetal brain.
Proteins: Structure, Function, and Bioinformatics.
28:457-460.
1997
|
|
| 1997
|
Preliminary crystallographic study on a low molecular weight form of bacterial plasminogen activator staphylokinase.
Acta Crystallographica Section D: Biological Crystallography.
53:480-481.
1997
|
|
| 1997
|
Purification, crystallization and preliminary X-ray diffraction studies of recombinant calcium-binding domain of the small subunit of porcine calpain.
Acta Crystallographica Section D: Biological Crystallography.
53:474-476.
1997
|
|
| 1996
|
Crystallographic study of the NAD-dependent M Hoc bond rial malic enzyme from the parasitic roundworm ascaris suum.
The FASEB Journal.
10.
1996
|
|
| 1993
|
Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form..
Acta Crystallographica Section D: Biological Crystallography.
49:423-427.
1993
|
|
| 1992
|
Immobilized metal affinity chromatography of bacterially expressed proteins engineered to contain an alternating-histidine domain.
Methods.
4:57-67.
1992
|
|
| 1992
|
Purification and characterization of heterodimeric human immunodeficiency virus type 1 (HIV-1) reverse transcriptase produced by in vitro processing of p66 with recombinant HIV-1 protease.
Journal of Biological Chemistry.
267:14227-14232.
1992
|
|
| 1992
|
Resolution of microheterogeneity associated with recombinant HIV-1 heterodimeric reverse transcriptase.
Protein Expression and Purification.
3:151-159.
1992
|
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