• Dr. David C. Cleveland received his medical degree from the University of Alabama at Birmingham and completed his pediatric cardiovascular surgery fellowship at the Hospital for Sick Children in Toronto Canada. Among other positions, Dr. Cleveland has served as the chief of pediatric cardiac surgery for the Children’s Hospital in Buffalo, The Children’s Hospital at Medical City Dallas, and St. Joseph’s Hospital and Medical Center in Phoenix, Arizona. While in Phoenix, he founded the Eller Congenital Heart Center and served as its executive director until his departure in 2011.

    His special interests include early repair of complex congenital heart disease, fetal intervention, adult congenital heart disease, and outcomes measurement for continuous performance improvement.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Will previous palliative surgery for congenital heart disease be detrimental to subsequent pig heart xenotransplantation?Transplant Immunology.  74. 2022
    2022 Informed Consent for Potential Recipients of Pig Kidney Xenotransplantation in the United StatesTransplantation.  106:1754-1762. 2022
    2022 The Genetically Engineered Heart as a Bridge to Allotransplantation in Infants Just Around the Corner?Annals of Thoracic Surgery.  114:536-544. 2022
    2022 The potential of genetically engineered pig heart transplantation in infants with complex congenital heart diseasePediatric Transplantation.  26. 2022
    2022 Cardiac and Pulmonary Histopathology in Baboons Following Genetically-Engineered Pig Orthotopic Heart TransplantationAnnals of transplantation: quarterly of the Polish Transplantation Society.  27. 2022
    2022 Consensus statement on heart xenotransplantation in children: Toward clinical translationJournal of Thoracic and Cardiovascular Surgery2022
    2022 Health-Related Quality of Life After Single Ventricle Palliation or Tetralogy of Fallot RepairPediatric Cardiology2022
    2021 Addressing concerns toward xenotransplantationJournal of Cardiac Surgery.  36:4821. 2021
    2021 Gender Differences in Cardiothoracic Surgery Interest Among General Surgery ApplicantsAnnals of Thoracic Surgery.  112:961-967. 2021
    2021 A perspective on the potential detrimental role of inflammation in pig orthotopic heart xenotransplantationXenotransplantation.  28. 2021
    2021 Tachyarrhythmia as a possible symptom of coronavirus in a neonate diagnosed with transposition of the great arteriesJournal of Cardiac Surgery.  36:2578-2581. 2021
    2021 Attitudes toward xenotransplantation: A survey of parents and pediatric cardiac providersPediatric Transplantation.  25. 2021
    2021 Racial differences in attitudes to clinical pig organ XenotransplantationXenotransplantation.  28. 2021
    2021 Clinical trials of pediatric cardiac xenotransplantationAmerican Journal of Transplantation.  21:433-434. 2021
    2021 The first clinical trial—Kidney or heart?Xenotransplantation.  28. 2021
    2020 The immune system in infants: Relevance to xenotransplantationPediatric Transplantation.  24. 2020
    2020 Paediatric xenotransplantation clinical trials and the right to withdrawJournal of Medical Ethics.  46:311-315. 2020
    2020 Anti-Pig Antibody in Infants: Can a Genetically Engineered Pig Heart Bridge to Allotransplantation?Annals of Thoracic Surgery.  109:1268-1273. 2020
    2020 Recommendations to the IRB review process in preparation of xenotransplantation clinical trialsXenotransplantation.  27. 2020
    2020 Evaluation of Cardiothoracic Surgery Residency and Fellowship Program WebsitesJournal of Surgical Research.  246:200-206. 2020
    2019 In Search of the Ideal Valve: Optimizing Genetic Modifications to Prevent Bioprosthetic DegenerationAnnals of Thoracic Surgery.  108:624-635. 2019
    2019 The “Baby Fae” baboon heart transplant—Potential cause of rejectionXenotransplantation.  26. 2019
    2019 The Case for Cardiac Xenotransplantation in Neonates: Is Now the Time to Reconsider Xenotransplantation for Hypoplastic Left Heart Syndrome?Pediatric Cardiology.  40:437-444. 2019
    2019 Congenitally Corrected Transposition Presenting in the First Year of Life: Survival and Fate of the Systemic Right VentricleWorld Journal for Pediatric and Congenital Heart Surgery.  10:42-49. 2019
    2018 An approach to induction of tolerance to pig cardiac xenografts in neonatesXenotransplantation.  25. 2018
    2018 Furosemide response predicts acute kidney injury after cardiac surgery in infants and neonatesPediatric Critical Care Medicine.  19:310-317. 2018
    2018 Correction to: Routine Sildenafil Does Not Improve Clinical Outcomes After Fontan Operation (Pediatr Cardiol, (2017), 38, (1703-1708), 10.1007/s00246-017-1716-4)Pediatric Cardiology.  39:644-645. 2018
    2017 Routine Sildenafil Does Not Improve Clinical Outcomes After Fontan OperationPediatric Cardiology.  38:1703-1708. 2017
    2017 Central Venous to Arterial C o 2 Difference after Cardiac Surgery in Infants and Neonates∗Pediatric Critical Care Medicine.  18:228-233. 2017
    2017 Outcomes of Patients Who Undergo Cardiac Surgical Procedures After Liver TransplantationAnnals of Thoracic Surgery.  103:541-545. 2017
    2017 Current Solutions for Long-Segment Tracheal ReconstructionAnnals of Thoracic and Cardiovascular Surgery.  23:66-75. 2017
    2017 Current solutions for long-segment tracheal reconstructionAnnals of Thoracic and Cardiovascular Surgery.  23:66-75. 2017
    2016 Early Postoperative Albumin Administration Contributes to Morbidity After the Fontan OperationPediatric Cardiology.  37:1278-1283. 2016
    2016 Late Left Ventricular Outflow Tract Obstruction Following the Rastelli Operation: Expectations Out to 20 YearsWorld Journal for Pediatric and Congenital Heart Surgery.  7:605-610. 2016
    2015 Health-Related Quality of Life in Adult Survivors After the Fontan OperationSeminars in Thoracic and Cardiovascular Surgery.  27:299-306. 2015
    2015 Surgical and anesthetic management of a mediastinal fatty tumor: LipoblastomaAnnals of Thoracic Surgery.  100:e97-e98. 2015
    2015 Postoperative hydrocortisone infusion reduces the prevalence of low cardiac output syndrome after neonatal cardiopulmonary bypassPediatric Critical Care Medicine.  16:629-636. 2015
    2014 The modern Fontan operation shows no increase in mortality out to 20 years: A new paradigmJournal of Thoracic and Cardiovascular Surgery.  148:2517-2524.e1. 2014
    2013 Unusual reversed wall motion pattern in a patient with recurrent Takotsubo cardiomyopathyCanadian Journal of Cardiology.  29:1015.e13-1015.e14. 2013
    2009 Prolonged use of dexmedetomidine in the paediatric cardiothoracic intensive care unitCardiology in the Young.  19:98-104. 2009
    2007 Modified Superior Repair for Supracardiac Total Anomalous Pulmonary Venous Connection in the AdultAnnals of Thoracic Surgery.  84:312-313. 2007
    2004 Horseshoe lung with left lung hypoplasia and critical pulmonary venous stenosisAnnals of Thoracic Surgery.  77:1085-1087. 2004
    1996 Calcifying fibrous pseudotumor of the chest wallAnnals of Thoracic Surgery.  62:873-874. 1996
    1995 Neurodevelopmental outcome of infants with hypoplastic left heart syndromeJournal of Pediatrics.  126:496-498. 1995
    1994 Three-dimensional reconstruction of ultrafast chest CT for diagnosis and operative planning in a child with right pneumonectomy syndromeChest.  106:973-974. 1994
    1993 Neonatal pneumonectomyAnnals of Thoracic Surgery.  56:596-597. 1993
    1993 Treatment of persistent pulmonary hypertension in the newborn lamb by inhaled nitric oxideJournal of Pediatrics.  122:743-750. 1993
    1992 Failure of cryopreserved homograft valved conduits in the pulmonary circulation.Circulation.  86:II150-II153. 1992
    1992 Surgical connections from ventricle to pulmonary artery. Comparison of four types of valved implants.Circulation.  86:II154-II158. 1992
    1992 Failure of cryopreserved homograft valved conduits in the pulmonary circulationCirculation.  86. 1992
    1992 Surgical connections from ventricle to pulmonary artery: Comparison of four types of valved implantsCirculation.  86. 1992
    1991 Results of the Fontan procedure for patients with univentricular heartAnnals of Thoracic Surgery.  52:1266-1271. 1991
    1984 Congenital pulmonary vein stenosisAmerican Journal of Cardiology.  54:369-375. 1984
    1984 Surgical treatment of acute myocardial infarction.The Alabama journal of medical sciences.  21:175-177. 1984
    1984 Surgical Treatment of Tricuspid AtresiaAnnals of Thoracic Surgery.  38:447-457. 1984
    1983 Treatment of Intra-atrial Cardiac TumorsJAMA: Journal of the American Medical Association.  249:2799-2802. 1983


    Year Title Altmetric
    2020 Cardiac xenotransplantation.  171-192. 2020

    Teaching Overview

  • Dr. Cleveland has a major interest in developing medical student educational programs and enhancing resident training. He has been the Program Director of the Thoracic Surgery Residency Program since 2016.
  • Education And Training

  • UAB Hospital, Internship
  • UAB Hospital, Residency
  • UAB Hospital, Residency
  • University of Toronto Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine, University of Alabama at Birmingham 1979
  • Full Name

  • David Cleveland