Positions

Selected Publications

Academic Article

Year Title Altmetric
2016 Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureusScientific Reports.  6. 2016
2014 Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infectionJournal of Antimicrobial Chemotherapy.  70:1453-1465. 2014
2012 Fine specificity and cross-reactions of monoclonal antibodies to group B streptococcal capsular polysaccharide type IIIVaccine.  30:4849-4858. 2012
2012 Endolysins as AntimicrobialsAdvances in virus research.  83:299-365. 2012
2010 Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cellsCancer Letters.  298:238-249. 2010
2010 Characterization of the enzymes encoded by the anthrose biosynthetic operon of Bacillus anthracisJournal of Bacteriology.  192:5053-5062. 2010
2010 A novel glucosyltransferase is required for glycosylation of a serine-rich adhesin and biofilm formation by Streptococcus parasanguinisJournal of Biological Chemistry.  285:12140-12148. 2010
2010 Cleavage Specificity of Enterococcus faecalis EnpA (EF1473), a Peptidoglycan Endopeptidase Related to the LytM/Lysostaphin Family of MetallopeptidasesJournal of Molecular Biology.  398:507-517. 2010
2009 Identification of the UDP-N-acetylglucosamine 4-epimerase involved in exosporium protein glycosylation in Bacillus anthracisJournal of Bacteriology.  191:7094-7101. 2009
2009 LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cellsFEMS Microbiology Letters.  294:52-60. 2009
2008 A conserved domain of previously unknown function in Gap1 mediates protein-protein interaction and is required for biogenesis of a serine-rich streptococcal adhesinMolecular Microbiology.  70:1094-1104. 2008
2008 A new model of pneumococcal lipoteichoic acid structure resolves biochemical, biosynthetic, and serologic inconsistencies of the current modelJournal of Bacteriology.  190:2379-2387. 2008
2008 Anthrose biosynthetic operon of Bacillus anthracisJournal of Bacteriology.  190:2350-2359. 2008
2007 LambdaSa1 and LambdaSa2 prophage lysins of Streptococcus agalactiaeApplied and Environmental Microbiology.  73:7150-7154. 2007
2007 Discovery of a new capsular serotype (6C) within serogroup 6 of Streptococcus pneumoniaeJournal of Clinical Microbiology.  45:1225-1233. 2007
2006 Endopeptidase and glycosidase activities of the bacteriophage B30 lysinApplied and Environmental Microbiology.  72:6825-6828. 2006
2006 The cell lysis activity of the Streptococcus agalactiae bacteriophage B30 endolysin relies on the cysteine, histidine-dependent amidohydrolase/peptidase domainApplied and Environmental Microbiology.  72:5108-5112. 2006
2006 Peptidoglycan hydrolase fusions maintain their parental specificitiesApplied and Environmental Microbiology.  72:2988-2996. 2006
2004 Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporiumJournal of Biological Chemistry.  279:30945-30953. 2004
2004 The bifunctional peptidoglycan lysin of Streptococcus agalactiae bacteriophage B30.Microbiology.  150:2079-2087. 2004
2004 The bifunctional peptidoglycan lysin of Streptococcus agalactiae bacteriophage B30Microbiology.  150:2079-2087. 2004
2002 The hyaluronan lyase of Streptococcus pyogenes bacteriophage H4489ABiochemical Journal.  365:317-322. 2002
2000 Characterization of the active site of group B streptococcal hyaluronan lyaseProteins: Structure, Function, and Bioinformatics.  40:675. 2000
2000 Erratum: Characterization of the active site of group B streptococcal hyaluronan lyase (Proteins: Structure, function and genetics)Proteins: Structure, Function, and Bioinformatics.  40:675. 2000
2000 Characterization of the active site of group B streptococcal hyaluronan lyaseProteins: Structure, Function, and Bioinformatics.  40:126-134. 2000
2000 Action pattern and substrate specificity of the hyaluronan lyase from group B streptococciBiochemical Journal.  348:465-471. 2000
1997 Identification of a histidine residue essential for enzymatic activity of group B streptococcal hyaluronate lyaseBiochemical and Biophysical Research Communications.  231:379-382. 1997
1997 Specificity of the hyaluronate lyase of group-B streptococcus toward unsulphated regions of chondroitin sulphateBiochemical Journal.  327:65-71. 1997
1996 Characterization of PepB, a group B streptococcal oligopeptidaseInfection and Immunity.  64:3401-3406. 1996
1996 Hyaluronidase promotes gbs invasion in newborn ratsJournal of Investigative Medicine.  44. 1996
1994 Cloning and expression of the gene for group B streptococcal hyaluronate lyaseJournal of Biological Chemistry.  269:30113-30116. 1994
1994 Characterization of the group B Streptococcal hyaluronate lyaseArchives of Biochemistry and Biophysics.  315:431-437. 1994
1993 Capsular type-specific polysaccharide partially inhibits group B streptococcus-induced pulmonary hypertensionThe American review of respiratory disease.  148:152-157. 1993
1993 Group B streptococcal neuraminidase is actually a hyaluronidaseInfection and Immunity.  61:3234-3239. 1993
1992 Murine monoclonal antibodies to type Ib polysaccharide of group B streptococci bind to human milk oligosaccharidesInfection and Immunity.  60:1598-1602. 1992
1992 Proton NMR study on rhamnolipids produced by Pseudomonas aeruginosaMagnetic Resonance in Chemistry.  30:1025-1026. 1992
1992 Role of capsule in pulmonary hypertension induced by Group B streptococcusPediatric Research.  31:386-390. 1992
1991 Structure of the type-specific polysaccharide antigen of Streptococcus rattusCarbohydrate Research.  210:247-254. 1991
1990 Mucosal and systemic responses to an oral liposome-Streptococcus mutans carbohydrate vaccine in humansRegional immunology.  3:289-296. 1990
1990 Effect of fibronectin on IgA-mediated uptake of type III group B streptococci by phagocytesJournal of Infectious Diseases.  161:236-241. 1990
1990 The group B streptococci: From natural history to the specificity of antibodiesSeminars in Perinatology.  14:10-21. 1990
1989 Seroepidemiology of group B streptococcus type III colonization at delivery.Journal of Infectious Diseases.  159:1139-1142. 1989
1989 An IgA monoclonal antibody directed against type III antigen on group B streptococci acts as an opsoninJournal of Immunology.  143:3338-3342. 1989
1988 Structure of the group G Streptococcal polysaccharideCarbohydrate Research.  173:255-262. 1988
1988 Immunochemical characterization of the polysaccharide antigens of group B streptococci.Reviews of infectious diseases.  10 Suppl 2. 1988
1988 Seroepidemiology of group B streptococcus type II antibody specificityEpidemiology and Infection.  101:347-354. 1988
1988 Specificity of monoclonal antibodies against group B streptococcus type II and inhibition of their binding by human secretionsPediatric Research.  24:68-72. 1988
1987 Structure of the serotype f polysaccharide antigen of Streptococcus mutansCarbohydrate Research.  166:123-131. 1987
1987 Proton nuclear magnetic resonance measurement of the amide hydrogen exchange rates of group A streptococcal polysaccharide in H2OBiochemical and Biophysical Research Communications.  143:685-690. 1987
1987 Chemical Marker for the Differentiation of Group A and Group B Streptococci by Pyrolysis–Gas Chromatography–Mass SpectrometryAnalytical Chemistry.  59:1410-1413. 1987
1987 Type-specific antibodies against group B streptococci in human serum, saliva and vaginal secretions.Advances in Experimental Medicine and Biology.  216 B:995-1003. 1987
1986 Characterization of the group A streptococcal polysaccharide by two-dimensional 1H-nuclear-magnetic-resonance spectroscopyCarbohydrate Research.  155:193-199. 1986
1986 Characterization of the serotype e polysaccharide antigen of Streptococcus mutansMolecular Immunology.  23:141-145. 1986
1986 Type-specific monoclonal antibody enhances the local phagocytic response to group B streptococcal infectionJournal of Infectious Diseases.  153:1170-1173. 1986
1985 Structure of the group-specific polysaccharide of group E StreptococcusCarbohydrate Research.  144:289-296. 1985
1985 Seroepidemiological studies of group B streptococcus type IIJournal of Infectious Diseases.  151:1073-1080. 1985
1985 C-Reactive Protein Binds Leishmanial Excreted FactorsExperimental Biology and Medicine.  178:500-503. 1985
1985 Monoclonal antibody preparations for immunotherapy of experimental GBS infection.Antibiotics and chemotherapy.  35:254-266. 1985
1984 LPS regulation of the immune response: Separate mechanisms for murine B cell activation by lipid A (direct) and polysaccharide (macrophage-dependent) derived from Bacteroides LPSJournal of Immunology.  133:2294-2300. 1984
1984 Interaction of group B streptococcal type-specific polysaccharides with wheat germ agglutinin and other lectinsJournal of Immunological Methods.  72:269-277. 1984
1984 Fibronectin enhances the opsonic and protective activity of monoclonal and polyclonal antibody against group B streptococciJournal of Experimental Medicine.  159:1618-1628. 1984
1984 Characterization of the group-specific polysaccharide of group B StreptococcusArchives of Biochemistry and Biophysics.  235:385-392. 1984
1983 Protection of mice from experimental infection with type III group B streptococcus using monoclonal antibodiesJournal of Experimental Medicine.  158:1006-1011. 1983
1983 Antigens of mycoplasma hominisSexually Transmitted Diseases.  10:247-255. 1983
1982 High-resolution 1H- and 13C-n.m.r. spectra of the group A-variant streptococcal polysaccharideCarbohydrate Research.  110:315-319. 1982
1982 Flash heater derivatization of unconjugated bile acids using trimethylanilinium hydroxide. Rapid analysis by capillary gas-liquid chromatographyJournal of Chromatography - Biomedical Applications.  231:155-160. 1982
1981 Glucitol is present in the group-specific polysaccharide of group BStreptococcusCurrent Microbiology: an international journal.  5:283-287. 1981
1981 Carbohydrate fingerprints of streptococcal cellsJournal of Clinical Microbiology.  13:89-92. 1981
1981 Glycosylation sites of influenza viral glycoproteins: Characterization of tryptic glycopeptides from the A/USSR(H1N1) hemagglutinin glycoproteinJournal of Virology.  37:549-558. 1981
1980 Preparation and characterisation of permethylated derivatives of bile acids, and their application to gas chromatographic analysisJournal of Chromatography - Biomedical Applications.  183:269-276. 1980
1980 Sensitive mass spectrometric procedure for the detection of bacterial cell wall components in rheumatoid jointsArthritis and Rheumatism.  23:608-610. 1980
1978 Sensitive gas chromatographic determination of the monosaccharide composition of glycoproteins using electron capture detectionJournal of Chromatography A.  152:487-494. 1978
1978 Isolation of carcinoembryonic antigen by an improved procedureMolecular Immunology.  15:385-387. 1978
1978 Isolation, Immunological Characterization, and Structural Studies of a Tumor Antigen Related to Carcinoembryonic AntigenCancer Research.  38:1041-1048. 1978
1977 Isolation and immunochemical and chemical characterization of carcinoembryonic antigen like substances in colon lavages of healthy individualsCancer Research.  37. 1977
1977 Gas chromatography of methyl glycosides as their trimethylsilyl ethers. The methanolysis and re-N-acetylation stepsJournal of Chromatography A.  133:133-139. 1977
1976 Physical characterization and structural studies of the carcinoembryonic antigenCancer Research.  36. 1976
1976 Sensitive gas chromatographic determination of the monosaccharide composition of glycoproteins using electron capture detectionJournal of Chromatography A.  152:487-494. 1976
1976 Methylation Analysis of the Carbohydrate Portion of Carcinoembryonic AntigenCancer Research.  36:1915-1917. 1976
1976 Physical Characterization and Structural Studies of the Carcinoembryonic AntigenCancer Research.  36:3482-3485. 1976
1976 Purification of Carcinoembryonic Antigen by Removal of Contaminating MucopolysaccharidesCancer Research.  36:4699-4701. 1976
1975 Mass spectrometry of fluorescamine derivatives of amino acids and peptidesBiochemical and Biophysical Research Communications.  65:312-316. 1975

Chapter

Year Title Altmetric
2004 Oligopeptidase PepB.  371-372. 2004

Education And Training

  • Doctor of Philosophy in Biochemistry, University of California System : Los Angeles 1975
  • Full Name

  • David Pritchard