• Dr. Colin Martin was appointed as an assistant professor in general surgery in 2012. A native of Delaware, Martin received his undergraduate degree from Carson Newman College. He began his education in medicine at Wayne State University School of Medicine from where he graduated in 2003. His surgical residency in general surgery was completed at University of Cincinnati in 2010. He completed his postdoctoral research fellowship in 2008 at Cincinnati Children’s Hospital and his pediatric surgery fellowship in 2012 at Vanderbilt University. Dr. Martin is a specialist in intestinal rehabilitation surgery and scientist. His research interests include Mucosal immunology and B –cell mediated antibody development. Dr. Martin presently serves as Surgical Director of Georgeson Center for Intestinal Rehabilitation.

    Dr. Martin’s clinical interests include intestinal failure and necrotizing enterocolitis. He has a special interest in the role of innate immunity in intestinal diseases of prematurity.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2023 Impact of maternal factors, environmental factors, and race on necrotizing enterocolitisSeminars in Perinatology.  47. 2023
    2022 Therapeutic potential of human breast milk derived exosomesJournal of Nanoparticle Research.  24. 2022
    2022 Reduction of Central-line-Associated Bloodstream Infections in a Tertiary Neonatal Intensive Care Unit through Simulation Education 2022
    2022 Rare case report of closing gastroschisis with an absent common bile ductJournal of Pediatric Surgery Case Reports.  85. 2022
    2022 Examination of Intersectionality and the Pipeline for Black Academic SurgeonsJAMA Surgery.  157:327-334. 2022
    2022 Climate survey development to assess the DEI gap across surgical specialties in an academic institution 2022
    2022 Barriers and facilitators for under-represented in medicine (URiM) medical students interested in surgical sub-specialties 2022
    2021 Perforated Appendicitis during a Pandemic: The Downstream Effect of COVID-19 in ChildrenJournal of Surgical Research.  268:263-266. 2021
    2021 Scheduled Empiric Antibiotics May Alter the Gut Microbiome and Nutrition Outcomes in Pediatric Intestinal FailureNutrition in Clinical Practice.  36:1230-1239. 2021
    2021 Reassessing career pathways of surgical leaders: An examination of surgical leaders’ early accomplishments 2021
    2021 Effectiveness of a central line associated blood stream infection protocol in a pediatric population 2021
    2021 Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical TrialAnnals of Surgery.  274:e370-e380. 2021
    2021 Stress and the Gut-Brain Axis: Implications for Cancer, Inflammation and SepsisJournal of Surgical Research.  266:336-344. 2021
    2021 Trending diversity: Reviewing four-decades of graduating fellows and the current leadership in pediatric surgeryJournal of Pediatric Surgery.  56:1294-1298. 2021
    2021 A Novel Use of Artificial Intelligence to Examine Diversity and Hospital PerformanceJournal of Surgical Research.  260:377-382. 2021
    2021 Development and implementation of virtual grand rounds in surgery 2021
    2021 Effect of the COVID-19 Pandemic on Pediatric Intestinal Failure Healthcare DeliveryJournal of Parenteral and Enteral Nutrition.  45:50-56. 2021
    2020 Benchmarking Accomplishments of Leaders in American Surgery and Justification for Enhancing Diversity and InclusionAnnals of Surgery.  272:897-903. 2020
    2020 Prenatal stress increases IgA coating of offspring microbiota and exacerbates necrotizing enterocolitis-like injury in a sex-dependent mannerBrain, Behavior, and Immunity.  89:291-299. 2020
    2020 Key Determinants for Achieving Enteral Autonomy and Reduced Parenteral Nutrition Exposure in Pediatric Intestinal FailureJournal of Parenteral and Enteral Nutrition.  44:1263-1270. 2020
    2020 New directions in necrotizing enterocolitis with early-stage investigatorsPediatric Research.  88:35-40. 2020
    2020 RNASeq analysis reveals upregulation of complement C3 in the offspring gut following prenatal stress in miceImmunobiology.  225. 2020
    2020 Management of methemoglobinemia secondary to iNO use in a newborn with congenital diaphragmatic herniaJournal of Pediatric Surgery Case Reports.  57. 2020
    2020 The Society of Black Academic Surgeons CV benchmarking initiative: Early career trends of academic surgical leaders 2020
    2019 Depletion of dietary aryl hydrocarbon receptor ligands alters microbiota composition and functionScientific Reports.  9. 2019
    2019 Development of venous thrombi in a pediatric population of intestinal failureJournal of Pediatric Surgery.  54:2145-2148. 2019
    2019 The Effects of Gestational Psychological Stress on Neonatal Mouse Intestinal DevelopmentJournal of Surgical Research.  235:621-628. 2019
    2019 External parasitic twinsJournal of Pediatric Surgery Case Reports.  40:62-68. 2019
    2018 Systemic thrombolysis of an occlusive aortic thrombus in a neonate on extracorporeal membrane oxygenation 2018
    2018 Editor’s ChoiceInnate Immunity.  24:277. 2018
    2018 Human breast milk-derived exosomes attenuate cell death in intestinal epithelial cellsInnate Immunity.  24:278-284. 2018
    2018 Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8Pediatric Research.  83:943-953. 2018
    2018 Central venous line associated osteomyelitis in children with intestinal failureJournal of Pediatric Surgery Case Reports.  29:66-68. 2018
    2017 Erythropoietin-induced cytoprotection in intestinal epithelial cells is linked to system Xc-Experimental Cell Research.  352:202-206. 2017
    2017 Survey on Robot-Assisted Surgical Techniques Utilization in US Pediatric Surgery FellowshipsJournal of Laparoendoscopic and Advanced Surgical Techniques.  27:186-190. 2017
    2016 Quintuplets: 5 Cases of NEC. Are There Other Risk Factors?Fetal and Pediatric Pathology.  35:425-433. 2016
    2016 Outcome assessment of renal replacement therapy in neonatesJournal of Surgical Research.  204:34-38. 2016
    2016 Risk factors for stricture formation after esophageal atresia repairJournal of Laparoendoscopic and Advanced Surgical Techniques.  26:393-398. 2016
    2016 Altered T-Cell Balance in Lymphoid Organs of a Mouse Model of Colorectal Cancer 2016
    2015 Environmental-mediated intestinal homeostasis in neonatal miceJournal of Surgical Research.  198:494-501. 2015
    2015 Routine utilization of Single-Incision Pediatric Endosurgery (SIPES): A 5-year institutional experienceJournal of Laparoendoscopic and Advanced Surgical Techniques.  25:252-255. 2015
    2015 Single-incision pediatric endosurgery (SIPES) splenectomy: what dictates the need for additional ports? 2015
    2015 Pathogenesis of necrotizing enterocolitis: Modeling the innate immune responseAmerican Journal of Pathology.  185:4-16. 2015
    2012 Concordance of imaging modalities and cost minimization in the diagnosis of pediatric choledochal cystsPediatric Surgery International.  28:615-621. 2012
    2012 Race disparities in firearm injuries and outcomes among Tennessee childrenJournal of Pediatric Surgery.  47:1196-1203. 2012
    2011 Race disparities in wilms tumor incidence and biologyJournal of Surgical Research.  170:112-119. 2011
    2010 Severity of head computed tomography scan findings fail to explain racial differences in mortality following child abuse 2010
    2009 Intestinal resection induces angiogenesis within adapting intestinal villiJournal of Pediatric Surgery.  44:1077-1083. 2009
    2009 Transanal rectosigmoid resection for severe intractable idiopathic constipationJournal of Pediatric Surgery.  44:1285-1291. 2009
    2009 Hirschsprung disease and fecal incontinence: diagnostic and management strategiesJournal of Pediatric Surgery.  44:271-277. 2009
    2008 Despite overall low pediatric head injury mortality, disparities exist between racesJournal of Pediatric Surgery.  43:1858-1864. 2008
    2008 Lessons learned: optimization of a murine small bowel resection modelJournal of Pediatric Surgery.  43:1018-1024. 2008
    2008 Pediatric traumatic brain injury: An update of research to understand and improve outcomesCurrent Opinion in Pediatrics.  20:294-299. 2008
    2008 Resection-induced intestinal adaptation and the role of enteric smooth muscleJournal of Pediatric Surgery.  43:1011-1017. 2008
    2008 Alarming trends in the improper use of motor vehicle restraints in children: implications for public policy and the development of race-based strategies for improving complianceJournal of Pediatric Surgery.  43:200-207. 2008


    Year Title Altmetric
    2019 Tracheal Esophageal Fistula.  620-623. 2019

    Research Overview

  • Research in Dr. Martin’s laboratory focuses on the aryl-hydrocarbon receptor (AhR) and its role in modulating intestinal injury in neonates, explores the novel mechanistic link between AhR stimulation of B cell mediated intestinal homeostasis and the mechanistic link between neonatal microbial environment and the developing immune system.
  • Education And Training

  • UC Health - University Hospital, Internship
  • UC Health - University Hospital, Residency
  • Vanderbilt University Medical Center, Postdoctoral Fellowship
  • Doctor of Medicine, Wayne State University 2003
  • Full Name

  • Colin Martin