Positions

Overview

  • Dr. Camilla (Margaroli) Bell received her master degree in Medical Biology at the University of Lausanne (Switzerland) in 2015, and her PhD in Immunology and Molecular Pathogenesis in 2019 from the Graduate Division of Biological and Biomedical Sciences at Emory University (Atlanta, GA). During her thesis in Dr. Tirouvanziam’s group, Dr. Bell studied the mechanisms leading to neutrophil plasticity in chronic diseases, with a primary focus on lung inflammation in infants and adults affected by cystic fibrosis. She continued working on mechanisms regulating airway inflammation upon infection (including SARS-CoV-2) during her postdoctoral training in Dr. Amit Gaggar’s group at the University of Alabama at Birmingham (UAB).

    Currently, Dr. Bell is an assistant professor in the Department of Pathology at UAB.

    • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Plasticity towards Rigidity: A Macrophage Conundrum in Pulmonary Fibrosis.  International Journal of Molecular Sciences.  23. 2022
    2022 Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis. 2022
    2022 Pilot study of inflammatory biomarkers in matched induced sputum and bronchoalveolar lavage of 2-year-olds with cystic fibrosis.  Pediatric pulmonology. Supplement.  57:2189-2198. 2022
    2022 Pseudomonas aeruginosa modulates neutrophil granule exocytosis in an in vitro model of airway infection.  Immunology and Cell Biology.  100:352-370. 2022
    2022 An in vivo model for extracellular vesicle–induced emphysema.  JCI Insight.  7. 2022
    2022 Gastrointestinal Manifestations of COVID-19 Infection: Clinicopathologic Findings in Intestinal Resections Performed at Single Institution.  Frontiers in Medicine.  9. 2022
    2022 Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease.  Journal of Cystic Fibrosis.  2022
    2021 Mass production of human airway-like neutrophils via transmigration in an organotypic model of human airways.  STAR Protocols.  2. 2021
    2021 Extracellular vesicles: Progress and challenges in the study of human immunodeficiency virus and cocaine-associated pulmonary arterial hypertension.  American Journal of Respiratory Cell and Molecular Biology.  65:341-342. 2021
    2021 Mechanistic analysis and significance of sphingomyelinase-mediated decreases in transepithelial CFTR currents in nHBEs.  Physiological Reports.  9. 2021
    2021 Spatial mapping of SARS-CoV-2 and H1N1 lung injury identifies differential transcriptional signatures.  Cell Reports Medicine.  2. 2021
    2021 Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.  Cell Reports Medicine.  2. 2021
    2021 Prolyl endopeptidase contributes to early neutrophilic inflammation in acute myocardial transplant rejection.  JCI Insight.  6. 2021
    2021 Functional and transcriptional adaptations of blood monocytes recruited to the cystic fibrosis airway microenvironment in vitro.  International Journal of Molecular Sciences.  22:1-15. 2021
    2021 Positive Retrospective SARS-CoV-2 Testing in a Case of Acute Respiratory Distress Syndrome of Unknown Etiology..  Case Reports in Pulmonology.  2021. 2021
    2021 Use of Telepathology to Facilitate COVID-19 Research and Education through an Online COVID-19 Autopsy Biorepository..  Journal of Pathology Informatics.  12:48. 2021
    2021 Use of telepathology to facilitate COVID-19 research and education through an online COVID-19 autopsy biorepository.  Journal of Pathology Informatics.  12. 2021
    2020 Distinct compartmentalization of immune cells and mediators characterizes bullous pemphigoid disease.  Experimental Dermatology.  29:1191-1198. 2020
    2020 Airway profile of bioactive lipids predicts early progression of lung disease in cystic fibrosis.  Journal of Cystic Fibrosis.  19:902-909. 2020
    2020 Immunomodulation in cystic fibrosis: Why and how?.  International Journal of Molecular Sciences.  21. 2020
    2020 Neutrophil adaptations upon recruitment to the lung: New concepts and implications for homeostasis and disease.  International Journal of Molecular Sciences.  21. 2020
    2020 The immunosuppressive phenotype of tumor-infiltrating neutrophils is associated with obesity in kidney cancer patients.  OncoImmunology.  9. 2020
    2019 Neutrophil-Targeted, protease-Activated pulmonary drug delivery blocks airway and systemic inflammation.  JCI Insight.  4. 2019
    2019 Neutrophil Dysfunction in the Airways of Children with Acute Respiratory Failure Due to Lower Respiratory Tract Viral and Bacterial Coinfections.  Scientific Reports.  9. 2019
    2019 Elastase exocytosis by airway neutrophils is associated with early lung damage in children with cystic fibrosis.  American Journal of Respiratory and Critical Care Medicine.  199:873-881. 2019
    2019 Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung.  Cell.  176:113-126.e15. 2019
    2018 Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.  European Respiratory Journal.  52. 2018
    2016 Neutrophil plasticity enables the development of pathological microenvironments: implications for cystic fibrosis airway disease.  Molecular and Cellular Pediatrics.  3. 2016
    2016 Role of proapoptotic BH3-only proteins in Listeria monocytogenes infection.  European Journal of Immunology.  46:1427-1437. 2016

    Research Overview

  • Dr. Bell's research focuses on the interplay between the innate and adaptive immune system in pathologies affecting the cardiopulmonary system.

    • Principal Investigator On

    Investigator On

    Education And Training

  • University of Alabama at Birmingham Medicine, Postdoctoral Research
  • Doctor of Philosophy in Immunology, Emory University 2019

    • Full Name

  • Camilla Bell