| Year |
Title |
Altmetric |
| 2021
|
Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator.
Journal of Chemical Information and Modeling.
61:1762-1777.
2021
|
|
| 2018
|
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.
Journal of Biological Chemistry.
293:17685-17704.
2018
|
|
| 2018
|
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1
2018
|
|
| 2017
|
Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations.
Journal of Biological Chemistry.
292:14147-14164.
2017
|
|
| 2017
|
Direct binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric coupling between the Binding site and the NBD1:CL4 Interface s.
Molecular Pharmacology.
92:124-135.
2017
|
|
| 2017
|
Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function
2017
|
|
| 2016
|
A Guide to Differential Scanning Calorimetry of Membrane and Soluble Proteins in Detergents.
Methods in Enzymology.
567:319-358.
2016
|
|
| 2015
|
Restoration of NBD1 thermal stability is necessary and sufficient to correct Δf508 CFTR folding and assembly.
Journal of Molecular Biology.
427:106-120.
2015
|
|
| 2014
|
Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains.
Protein Science.
23:769-789.
2014
|
|
| 2012
|
Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator.
Journal of Biological Chemistry.
287:28480-28494.
2012
|
|
| 2011
|
A gene optimization strategy that enhances production of fully functional P-Glycoprotein in Pichia pastoris.
PLoS One.
6.
2011
|
|
| 2010
|
Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis.
Protein Science.
19:1932-1947.
2010
|
|
| 2010
|
Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide-binding domain 1.
Protein Science.
19:1917-1931.
2010
|
|
| 2010
|
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant
2010
|
|
| 2009
|
SAR studies for a new class of antibacterial NAD biosynthesis inhibitors.
ACS combinatorial science.
11:617-625.
2009
|
|
| 2009
|
Virtual screening to identify lead inhibitors for bacterial NAD synthetase (NADs).
Bioorganic and Medicinal Chemistry Letters.
19:2001-2005.
2009
|
|
| 2008
|
Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.
Acta Crystallographica Section F: Structural Biology Communications.
64:893-898.
2008
|
|
| 2007
|
Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
Acta crystallographica. Section D, Structural biology.
63:891-905.
2007
|
|
| 2007
|
Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: Amide- and ether-linked tethered dimers with α-amino acid end groups.
Journal of Medicinal Chemistry.
50:2612-2621.
2007
|
|
| 2007
|
His-tag impact on structure.
Acta crystallographica. Section D, Structural biology.
63:295-301.
2007
|
|
| 2005
|
Förster resonance energy transfer measurements are consistent with a helical bundle model for lipid-free apolipoprotein A-I.
Biochemistry.
44:16413-16425.
2005
|
|
| 2005
|
Engineering mouse apolipoprotein A-I into a monomeric, active protein useful for structural determination.
Biochemistry.
44:14907-14919.
2005
|
|
| 2005
|
Tethered dimer inhibitors of NAD synthetase: Parallel synthesis of an aryl-substituted SAR library.
ACS combinatorial science.
7:898-904.
2005
|
|
| 2004
|
Role of inhibitor aliphatic chain in the thermodynamics of inhibitor binding to Escherichia coli enoyl-ACP reductase and the Phe203Leu mutant: A proposed mechanism for drug resistance.
Biochemistry.
43:13380-13389.
2004
|
|
| 2004
|
Dimethyl sulfoxide at 2.5% (v/v) alters the structural cooperativity and unfolding mechanism of dimeric bacterial NAD+ synthetase.
Protein Science.
13:830-841.
2004
|
|
| 2003
|
Deletion of DnaK's lid strengthens binding to the nucleotide exchange factor, GrpE: A kinetic and thermodynamic analysis.
Biochemistry.
42:9028-9040.
2003
|
|
| 2003
|
Tethered dimers as NAD synthetase inhibitors with antibacterial activity.
Journal of Medicinal Chemistry.
46:3371-3381.
2003
|
|
| 2002
|
NH3-dependent NAD+ synthetase from Bacillus subtilis at 1 Å resolution.
Acta crystallographica. Section D, Structural biology.
58:1138-1146.
2002
|
|
| 2001
|
Kinetic and calorimetric evidence for two distinct scaffolding protein binding populations within the bacteriophage P22 procapsid.
Biochemistry.
40:8962-8970.
2001
|
|
| 2001
|
Stabilization of active-site loops in NH3-dependent NAD+ synthetase from Bacillus subtilis.
Acta crystallographica. Section D, Structural biology.
57:806-812.
2001
|
|
| 2001
|
Structural models of human apolipoprotein A-I: A critical analysis and review
2001
|
|
| 2000
|
Stereoselective binding of an enantiomeric pair of stromelysin-1 inhibitors caused by conformational entropy factors.
Bioorganic and Medicinal Chemistry Letters.
10:2427-2430.
2000
|
|
| 2000
|
Down-regulation of cell surface receptors is modulated by polar residues within the transmembrane domain.
Molecular Biology of the Cell.
11:2643-2655.
2000
|
|
| 1999
|
Human apolipoprotein A-I: Structure determination and analysis of unusual diffraction characteristics.
Acta Crystallographica Section D: Biological Crystallography.
55:2013-2021.
1999
|
|
| 1999
|
Analysis of the binding of hydroxamic acid and carboxylic acid inhibitors to the stromelysin-1 (matrix metalloproteinase-3) catalytic domain by isothermal titration calorimetry.
Biochemistry.
38:13592-13601.
1999
|
|
| 1999
|
Crystallization of truncated human apolipoprotein A-I in a novel conformation.
Acta Crystallographica Section D: Biological Crystallography.
55:1578-1583.
1999
|
|
| 1999
|
The structure of human lipoprotein A-I. Evidence for the 'belt' model.
Journal of Biological Chemistry.
274:14541-14544.
1999
|
|
| 1998
|
The lipid-free structure of apolipoprotein A-I: Effects of amino- terminal deletions.
Biochemistry.
37:11714-11725.
1998
|
|
| 1998
|
Structural analysis of apolipoprotein A-I: Effects of amino- and carboxy-terminal deletions on the lipid-free structure.
Biochemistry.
37:945-955.
1998
|
|
| 1997
|
Crystal structure of truncated human apolipoprotein A-I suggests a lipid-bound conformation
1997
|
|
| 1997
|
Structural analysis of apolipoprotein A-I: Limited proteolysis of methionine-reduced and -oxidized lipid-free and lipid-bound human apo A-I.
Biochemistry.
36:7615-7624.
1997
|
|
| 1997
|
Truncation of the amine terminus of human apolipoprotein A-I substantially alters only the lipid-free conformation.
Biochemistry.
36:288-300.
1997
|
|
| 1996
|
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding
1996
|
|
| 1996
|
Storage stability of the solution formulation of sCD4 determined by DSC in comparison with two functional assays
1996
|
|
| 1995
|
Structural models of human apolipoprotein A-I
1995
|
|
| 1995
|
Interdomain Communication of T-Cell CD4 Studied by Absorbance and Fluorescence Difference Spectroscopy Measurements of Urea-Induced Unfolding.
Biochemistry.
34:6464-6474.
1995
|
|
| 1994
|
The amphipathic α helix: A multifunctional structural motif in plasma apolipoproteins.
Advances in protein chemistry and structural biology.
45:303-369.
1994
|
|
| 1993
|
Intracellular transport and virion incorporation of vpx requires interaction with other virus type-specific components.
Virology.
193:222-233.
1993
|
|
| 1992
|
Analysis of the Two-State Behavior of the Thermal Unfolding of Serum Retinol Binding Protein Containing a Single Retinol Ligand.
Biochemistry.
31:5560-5567.
1992
|
|
| 1992
|
The amphipathic helix in the exchangeable apolipoproteins: A review of secondary structure and function.
Journal of Lipid Research.
33:141-166.
1992
|
|
| 1992
|
Thermal stabilities of mutant Escherichia coli tryptophan synthase α subunits.
Molecular cell biology research communications : MCBRC.
292:34-41.
1992
|
|
| 1991
|
Role of amphipathic helixes in HDL structure/function.
Advances in Experimental Medicine and Biology.
285:131-140.
1991
|
|
| 1990
|
Amphipathic helix motif: Classes and properties
1990
|
|
| 1990
|
Use of synthetic peptide analogues to localize lecithin:cholesterol acyltransferase activating domain in apolipoprotein A-I.
Arteriosclerosis (Dallas, Tex.).
10:95-105.
1990
|
|
| 1989
|
Characterization of apoA-I-containing lipoprotein subpopulations secreted by HepG2 cells.
Journal of Lipid Research.
30:1429-1436.
1989
|
|
| 1989
|
Structure and thermal stability of monomeric bacteriorhodopsin in mixed pospholipid/detergent micelles
1989
|
|
| 1987
|
Characterization of high density lipoprotein subspecies: Structural studies by single vertical spin ultracentrifugation and immunoaffinity chromatography.
Journal of Lipid Research.
28:913-929.
1987
|
|
| 1987
|
pH Dependence of Bacteriorhodopsin Thermal Unfolding.
Biochemistry.
26:7431-7438.
1987
|
|
| 1985
|
Studies of synthetic peptide analogs of the amphiphatic helix. Correlation of structure with function.
Journal of Biological Chemistry.
260:10256-10262.
1985
|
|
| 1985
|
Studies of synthetic peptide analogs of the amphiphatic helix. Structure of complexes with dimyristoyl phosphatidylcholine.
Journal of Biological Chemistry.
260:10248-10255.
1985
|
|
| 1984
|
Structural Studies of Apolipoprotein A-I/Phosphatidylcholine Recombinants by High-Field Proton NMR, Nondenaturing Gradient Gel Electrophoresis, and Electron Microscopy.
Biochemistry.
23:359-367.
1984
|
|
| 1983
|
Studies of synthetic peptide analogs of the amphipathic helix. Competitive displacement of exchangeable apolipoproteins from native lipoproteins.
Journal of Biological Chemistry.
258:2290-2295.
1983
|
|
| 1982
|
Structural domains of vesicular stomatitis virus. A study by differential scanning calorimetry, thermal gel analysis, and thermal electron microscopy..
Journal of Biological Chemistry.
257:12-15.
1982
|
|
| 1982
|
Dynamics of Apolipoprotein-Phospholipid Interactions.
Biophysical Journal.
37:172-173.
1982
|
|
| 1982
|
Minimal Size Phosphatidylcholine Vesicles: Effects of Radius of Curvature on Head Group Packing and Conformation.
Biochemistry.
21:4569-4575.
1982
|
|
| 1982
|
Structural Domains in Vesicular Stomatitis Virus Membrane as Studied by Differential Scanning Calorimetry.
Biophysical Journal.
37:25-26.
1982
|
|
