Selected Publications

Academic Article

Year Title Altmetric
2020 Lifecycles of Individual Subretinal Drusenoid Deposits and Evolution of Outer Retinal Atrophy in Age-Related Macular Degeneration 2020
2019 Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and MacaqueHuman Gene Therapy.  30:571-589. 2019
2019 SubILM injection of AAV for gene delivery to the retinaMethods in Molecular Biology.  1950:249-262. 2019
2018 Dynamism of dot subretinal drusenoid deposits in age-related macular degeneration demonstrated with adaptive optics imagingRetina: the Journal of Retinal and Vitreous Diseases.  38:29-38. 2018
2017 Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR MutationsMolecular Therapy.  25:1866-1880. 2017
2016 Patients' adherence to recommended follow-up eye care after diabetic retinopathy screening in a publicly funded county clinic and factors associated with follow-up eye care useJAMA Ophthalmology.  134:1221-1228. 2016
2016 Highly efficient delivery of adeno-associated viral vectors to the primate retinaHuman Gene Therapy.  27:580-597. 2016
2016 Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular DegenerationOphthalmology.  123:344-351. 2016
2016 Novel methodology for creating macaque retinas with sortable photoreceptors and ganglion cellsFrontiers in Neuroscience.  10. 2016
2015 Feasibility and efficacy of diabetic retinopathy screening among youth with diabetes in a pediatric endocrinology clinic: A cross-sectional studyDiabetology and Metabolic Syndrome.  7. 2015
2015 Ocular bartonellosis in transplant recipients: Two case reports and review of the literatureTransplant Infectious Disease.  17:723-727. 2015
2014 Associations between abnormal rod-mediated dark adaptation and health and functioning in older adults with normal macular healthInvestigative Ophthalmology and Visual Science.  55:4776-4789. 2014
2014 Myofibroblast and extracellular matrix origins in proliferative vitreoretinopathyGraefes Archive for Clinical and Experimental Ophthalmology.  252:347-357. 2014
2014 Photoreceptor perturbation around subretinal drusenoid deposits as revealed by adaptive optics scanning laser ophthalmoscopyAmerican Journal of Ophthalmology.  158. 2014
2012 The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.Human Gene Therapy.  23:1101-1115. 2012
2009 Intraoperative retinal detachment prophylaxis in vitrectomy for retained cataract fragmentsJournal of Cataract and Refractive Surgery.  35:491-495. 2009
2008 Retinal detachment laser prophylaxisRetina Today.  63-66. 2008
2008 Acute posterior multifocal placoid pigment epitheliopathy and thalamic infarction.Retinal Cases and Brief Reports.  2:209-212. 2008
2006 Epidemiology of blinding trauma in the United States Eye Injury RegistryOphthalmic Epidemiology.  13:209-216. 2006
2006 Removal of epimacular proliferation (EMP) in eyes.Retina: the Journal of Retinal and Vitreous Diseases.  26. 2006
2006 Correspondence [1]Retina: the Journal of Retinal and Vitreous Diseases.  26:589. 2006
2006 UntitledRetina: the Journal of Retinal and Vitreous Diseases.  26:589-589. 2006
2005 Pars plana vitrectomy (PPV), lensectomy (PPL), scleral-sutured intraocular lens (SSIOL) and indirect ophthalmoscopy laser cerclage (IDOLC) prophylaxis for subluxed lens in Marfan syndrome patientsInvestigative Ophthalmology and Visual Science.  46. 2005
2005 Resolution of vitreomacular traction and cystoid macular edema by intravitreal injection of triamcinoloneInvestigative Ophthalmology and Visual Science.  46. 2005
2004 Birmingham Eye Trauma Terminology system (BETT)Journal Français D'Ophtalmologie.  27:206-210. 2004
2003 The effect of indocyanine-green on functional outcome of macular pucker surgery [7] (multiple letters)American Journal of Ophthalmology.  136:778-779. 2003
2002 Birmingham Eye Trauma Terminology (BETT): Terminology and classification of mechanical eye injuriesOphthalmology clinics of North America.  15:139-143. 2002
2002 Epidemiology and socioeconomicsOphthalmology clinics of North America.  15:145-151. 2002
2002 The ocular trauma score (OTS)Ophthalmology clinics of North America.  15:163-165. 2002
2001 Internal limiting membrane removal for traumatic macular holesOphthalmic Surgery, Lasers and Imaging.  32:308-315. 2001
2001 Changing patterns of eye injuries with age.Investigative Ophthalmology and Visual Science.  42:S679-S679. 2001
2001 Ciliary body surgery for hypotony due to cyclodialysis cleft and ciliary body detachment.Investigative Ophthalmology and Visual Science.  42:S816-S816. 2001
2001 Internal limiting membrane removal for traumatic macular holes.Investigative Ophthalmology and Visual Science.  42:S688-S688. 2001
2001 Multicenter trial of Cryotherapy for Retinopathy of Prematurity: Ophthalmological outcomes at 10 yearsJAMA Ophthalmology.  119:1110-1118. 2001
2000 Prophylactic scleral buckle for prevention of retinal detachment following vitrectomy for macular hole (multiple letters)British Journal of Ophthalmology.  84:673. 2000
2000 Macular hole repair in eyes with concomitant retinal detachment due to peripheral retinal tears.Investigative Ophthalmology and Visual Science.  41:S339-S339. 2000
2000 Serious fireworks-related eye injuriesOphthalmic Epidemiology.  7:139-148. 2000
2000 The epidemiology of serious eye injuries from the United States Eye Injury RegistryGraefes Archive for Clinical and Experimental Ophthalmology.  238:153-157. 2000
1999 An update of the epidemiology of serious eye injuries from the United States Eye Injury RegistryInvestigative Ophthalmology and Visual Science.  40:S989-S989. 1999
1999 Indirect ophthalmoscopic laser cerclage as prophylaxis for post-operative retinal detachment in macular hole surgeryInvestigative Ophthalmology and Visual Science.  40:S114-S114. 1999
1999 Internal limiting membrane removal in the management of idiopathic macular holeInvestigative Ophthalmology and Visual Science.  40:S114-S114. 1999
1999 Epidemiology of general and sports eye injuriesOphthalmology clinics of North America.  12:333-343. 1999
1998 Terson syndrome: Authors’ replyOphthalmology.  105:2162-2163. 1998
1998 Terson syndrome: Results of vitrectomy and the significance of vitreous hemorrhage in patients with subarachnoid hemorrhageOphthalmology.  105:472-477. 1998
1998 Terson syndrome [1] (multiple letters)Ophthalmology.  105:2161-2163. 1998
1997 Visual problems and pathological findings among football players: An epidemiologic studyInvestigative Ophthalmology and Visual Science.  38. 1997
1997 Tractional force generation by porcine muller cells: Stimulation by growth factors in human vitreousInvestigative Ophthalmology and Visual Science.  38:2053-2063. 1997
1997 Hemorrhagic macular cysts in Terson's syndrome and its implications for macular surgery.Developments in ophthalmology.  29:44-54. 1997
1997 The ocular trauma score (OTS): Developmental considerations and preliminary findingsInvestigative Ophthalmology and Visual Science.  38. 1997
1996 A new system of ocular trauma terminologyVision Research.  36:4111-4111. 1996
1996 Vitrectomy for Terson's syndromeVision Research.  36:365-365. 1996
1996 Protective eyewear for young athletesPediatrics.  98:311-313. 1996
1996 Development of an Ocular Trauma Score: Preliminary reportInvestigative Ophthalmology and Visual Science.  37. 1996
1996 Epidemiology of serious eye injuries in the United States Eye Injury Registry (USEIR) and the Hungarian Eye Injury Registry (HEIR)Investigative Ophthalmology and Visual Science.  37. 1996
1996 Epidemiology of serious eye injuries in the United States Eye Injury Registry (USEIR) and the Hungarian Eye Injury Registry (HEIR)Investigative Ophthalmology and Visual Science.  37:4391-4391. 1996
1996 Pathologic human vitreous stimulates development of tractional forces by porcine Muller cellsInvestigative Ophthalmology and Visual Science.  37. 1996
1996 A standardized classification of ocular traumaGraefes Archive for Clinical and Experimental Ophthalmology.  234:399-403. 1996
1996 A standardized classification of ocular traumaOphthalmology.  103:240-243. 1996
1996 Intraocular foreign bodies: Myths and truthsEuropean Journal of Ophthalmology.  6:464-471. 1996
1995 SERIOUS EYE INJURIES ASSOCIATED WITH FIREWORKS - UNITED-STATES, 1990-1994 (REPRINTED FROM MMWR, VOL 44, PG 449-452, 1995)JAMA: Journal of the American Medical Association.  274:110-111. 1995
1995 VITRECTOMY FOR TERSONS-SYNDROME - INDICATIONS AND RESULTSInvestigative Ophthalmology and Visual Science.  36:S1002-S1002. 1995
1995 Eye injury and the air bagCurrent Opinion in Ophthalmology.  6:38-44. 1995
1995 Pathologic Human Vitreous Promotes Contraction by Fibroblasts: Implications for Proliferative VitreoretinopathyJAMA Ophthalmology.  113:1545-1553. 1995
1995 Percentage scattergram to depict changes in large amounts of data Over timeOphthalmic Epidemiology.  2:45-48. 1995
1994 A NEW SYSTEM OF OCULAR TRAUMA TERMINOLOGYInvestigative Ophthalmology and Visual Science.  35:1696-1696. 1994
1994 BASEBALL-RELATED OCULAR TRAUMAInvestigative Ophthalmology and Visual Science.  35:1699-1699. 1994
1994 TEMPORARY KERATOPROSTHESIS VITRECTOMY FOR SEVERE OCULAR TRAUMAInvestigative Ophthalmology and Visual Science.  35:1260-1260. 1994
1994 Epidemiology of motor vehicle crash-related serious eye injuriesAccident Analysis and Prevention.  26:385-390. 1994
1994 Hemorrhagic Macular CystsOphthalmology.  101:1. 1994
1993 OCULAR TRAUMA TERMINOLOGY - ARE WE SPEAKING THE SAME LANGUAGEInvestigative Ophthalmology and Visual Science.  34:1115-1115. 1993
1993 THE EFFECT OF GENDER ON SERIOUS EYE INJURYInvestigative Ophthalmology and Visual Science.  34:1114-1114. 1993
1993 Air Bag: Friend or Foe?JAMA Ophthalmology.  111:1333-1334. 1993
1993 Magnetic intraocular foreign bodies in the posterior chamber of the eyeOphthalmologe.  90:539-548. 1993
1993 Nasal secretion and intraocular surgeryOphthalmic surgery.  24:780. 1993
1993 Ocular Injuries in Motor Vehicle CrashesOphthalmology.  100:1280. 1993
1993 Permanent intraocular magnetsRetina: the Journal of Retinal and Vitreous Diseases.  13:176-177. 1993
1992 EYE INJURIES CAUSED BY MOTOR-VEHICLE CRASHESInvestigative Ophthalmology and Visual Science.  33:782-782. 1992
1992 Collagen gel contraction by cells associated with proliferative vitreoretinopathyInvestigative Ophthalmology and Visual Science.  33:2429-2435. 1992
1992 Improvement of siderotic ERG.European Journal of Ophthalmology.  2:44-45. 1992
1991 ANALYSIS OF 2176 SERIOUS EYE INJURIES - THE UNITED-STATES-EYE-INJURY-REGISTRYInvestigative Ophthalmology and Visual Science.  32:885-885. 1991
1991 EPIDEMIOLOGY OF PEDIATRIC INJURIES FROM THE EYE INJURY REGISTRY OF ALABAMA (EIRA)Investigative Ophthalmology and Visual Science.  32:1223-1223. 1991
1991 Chemotic prolapse of the conjunctiva [1]Ophthalmic surgery.  22:241-242. 1991
1991 Endoscopic Surgery vs Temporary Keratoprosthesis VitrectomyJAMA Ophthalmology.  109:768. 1991
1990 Endophthalmitis due to Sporothrix schenckii after penetrating ocular injury.Annals of Ophthalmology.  22:385-388. 1990
1990 Vitrectomy in asteroid hyalosisRetina: the Journal of Retinal and Vitreous Diseases.  10:173-177. 1990
1989 Eye injury: Prevalence and prognosis by settingSouthern Medical Journal.  82:151-158. 1989
1989 Ocular self-mutilation.Annals of Ophthalmology.  21. 1989
1988 Serious eye trauma in Alabama.Alabama medicine : journal of the Medical Association of the State of Alabama.  58:36-40. 1988
1988 Evolving Techniques in the Treatment of Macular Detachment Caused by Optic Nerve PitsOphthalmology.  95:889-896. 1988
1988 Field evaluation of polycarbonate versus conventional safety glassesSouthern Medical Journal.  81:1534-1536. 1988
1988 Multicenter trial of cryotherapy for retinopathy of prematurity: Preliminary results.Pediatrics.  81:697-706. 1988
1988 No light perception: Prognostic significance in acute ocular traumaSurgical forum.  39:512-514. 1988
1988 Ocular Lawnmower InjuriesOphthalmology.  95:1367-1370. 1988
1987 Bilateral ocular shotgun injury.American Journal of Ophthalmology.  103:695-700. 1987
1987 Anterior segment ischemia after strabismus surgery in a child.American Journal of Ophthalmology.  103:833-834. 1987
1987 Bilateral ocular shotgun injuryAmerican Journal of Ophthalmology.  103:695-700. 1987
1987 Eye injury registry of Alabama (Preliminary report): Demographics and prognosis of severe eye injurySouthern Medical Journal.  80:810-816. 1987
1987 Globe Perforation From Peribulbar InjectionJAMA Ophthalmology.  105:749. 1987
1987 Recovery of Vision after Presumed Direct Optic Nerve InjuryOphthalmology.  94:1567-1569. 1987
1987 Visual side effects of isotretinoin therapySouthern Medical Journal.  80:1332. 1987
1986 Infectious endophthalmitis: an ocular emergency.Alabama medicine : journal of the Medical Association of the State of Alabama.  56:18-25. 1986
1986 Automated Regulation of Fluid Infusion Pressure During VitrectomyJAMA Ophthalmology.  104:1551. 1986
1986 Use of nondepolarizing anesthetic agents in penetrating ocular injuriesAnesthesiology.  65:108-109. 1986
1983 The role of endoscopic vitreous microsurgery in proliferative diabetic retinopathy.The Alabama journal of medical sciences.  20:286-288. 1983
1981 ANTI-TMA immunity in mice. III. Induction of L-tyrosine-p-azophenyltrimethylammonium (tyr(TMA)) specific helper T cells by the monovalent antigen or idiotypic antiseraJournal of Immunology.  126:2390-2396. 1981
1980 Anti-TMA immunity in mice. I. The appearance of cross-reactive idiotype(s) to the trimethylammonium (TMA) hapten in A/J miceJournal of Immunology.  124:215-221. 1980


Year Title Altmetric
2008 Injury involving the entire globe.  405-416. 2008
2008 Predicting the severity of an eye injury: The ocular trauma score (OTS).  17-22. 2008
2008 Terminology of mechanical injuries: The Birmingham eye trauma terminology (BETT).  3-11. 2008

Education And Training

  • St. Mary's Medical Center, Internship
  • Callahan Eye Foundation Hospital, Residency
  • Vitreoretinal Foundation, Residency
  • Doctor of Medicine in Ophthalmology Residency Program, Saint Louis University 1977
  • Full Name

  • Clark Witherspoon