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Carmen De Miguel
Assistant Professor
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cdemigue@uab.edu
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Carmen De Miguel
Assistant Professor
Positions
Associate Scientist (C)
,
UAB Immunology Institute
,
School of Medicine
Associate Scientist (C)
,
Comprehensive Diabetes Center
,
School of Medicine
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
Assistant Professor (P)
,
Medicine - Nephrology
,
Department of Medicine
Assistant Professor (S)
,
Cell, Developmental and Integrative Biology (CDIB)
,
Academic Joint Departments
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2022
Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness
.
Vascular Pharmacology
. 145.
2022
2022
Endothelin-1 Receptor B (ET
B
) Deficient Rats Fed High Salt Diet Display Differential Mitochondria-Related Gene Expression in the Kidney Cortex and Outer Medulla
2022
2022
Acclimation to a High-Salt Diet Is Sex Dependent
.
Journal of the American Heart Association
. 11.
2022
2021
Activation of G protein-coupled estrogen receptor 1 ameliorates proximal tubular injury and proteinuria in Dahl salt-sensitive female rats
2021
2021
Emerging role of the inflammasome and pyroptosis in hypertension
.
International Journal of Molecular Sciences
. 22:1-22.
2021
2021
The CAT-1 is out of the bag: Endothelial cationic amino acid transporter-1 is a critical player in cardiorenal syndrome type 2
.
Clinical Science
. 135:105-108.
2021
2020
Medroxyprogesterone opposes estradiol-induced renal damage in midlife ovariectomized Long Evans rats
2020
2020
ND-13, a DJ-1-derived peptide, attenuates the renal expression of fibrotic and inflammatory markers associated with unilateral ureter obstruction
.
International Journal of Molecular Sciences
. 21:1-16.
2020
2020
Evidence for g-protein–coupled estrogen receptor as a pronatriuretic factor
.
Journal of the American Heart Association
. 9.
2020
2020
Sex differences in redox homeostasis in renal disease: Sex-differences in renal redox signaling
.
Redox Biology
. 31.
2020
2019
Uncoupling Protein 2 Increases Blood Pressure in DJ-1 Knockout Mice
.
Journal of the American Heart Association
. 8.
2019
2019
Tauroursodeoxycholic acid (TUDCA) abolishes chronic high salt-induced renal injury and inflammation
.
Acta Physiologica
. 226.
2019
2018
Maternal separation enhances anticontractile perivascular adipose tissue function in male rats on a high-fat diet
2018
2018
Early life stress induces immune priming in kidneys of adult male rats
2018
2017
Long-term endothelin-a receptor antagonism provides robust renal protection in humanized sickle cell disease mice
.
Journal of the American Society of Nephrology
. 28:2443-2458.
2017
2017
Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney
.
Scientific Reports
. 7.
2017
2016
Free radical scavenging decreases endothelin-1 excretion and glomerular albumin permeability during type 1 diabetes
.
Physiological Reports
. 4.
2016
2016
APS awards outstanding high school students at the annual Intel International Science and Engineering Fair
.
Physiologist
. 59:200.
2016
2016
Endothelin-1 and the kidney: New perspectives and recent findings
.
Current Opinion in Nephrology and Hypertension
. 25:35-41.
2016
2015
APS presents awards to outstanding high school students at the annual Intel international science and engineering fair
.
Physiologist
. 58:262.
2015
2015
Endothelium-derived ET-1 and the development of renal injury
2015
2015
Obesity is associated with more activated neutrophils in African American male youth
.
International Journal of Obesity
. 39:26-32.
2015
2014
Inflammation and Hypertension: New Understandings and Potential Therapeutic Targets
.
Current Hypertension Reports
. 17.
2014
2014
Clopidogrel preserves whole kidney autoregulatory behavior in ANG II-induced hypertension
2014
2013
Mycophenolate mofetil prevents high-fat diet–induced hypertension and renal glomerular injury in dahl SS rats
.
Physiological Reports
. 1:1-11.
2013
2013
Interaction between NO synthase and NADPH oxidase in control of sodium transport by the renal thick ascending limb during diabetes
.
Acta Physiologica
. 209:148-155.
2013
2013
Does endoplasmic reticulum stress mediate endothelin-1-induced renal inflammation?
2013
2013
A genome-wide methylation study on obesity: Differential variability and differential methylation
.
Epigenetics
. 8:522-533.
2013
2011
High dietary protein exacerbates hypertension and renal damage in dahl SS rats by increasing infiltrating immune cells in the kidney
.
Hypertension
. 57:269-274.
2011
2011
Infiltrating T lymphocytes in the kidney increase oxidative stress and participate in the development of hypertension and renal disease
2011
2010
T lymphocytes mediate hypertension and kidney damage in Dahl salt-sensitive rats
2010
2009
Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodium-sensitive hypertension
2009
2008
Exogenous L-arginine ameliorates angiotensin II-induced hypertension and renal damage in rats
.
Hypertension
. 52:1084-1090.
2008
Research
Principal Investigator On
Defining the Role of Endothelin-1 in Hyperoxia-Induced Kidney Damage
awarded by
Alpha Omega Alpha Honor Medical Society
Endothelin-1 and Dendritic Cells in Salt-Sensitive Hypertension
awarded by
University of California, San Diego
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure - Research Supplement to Promote Diversity
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Role of Endothelin in Hypertension-Mediated Inflammation and End-Organ Damage
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Sex Differences in Diabetic Kidney Disease: The Innate Immune System and Endothelin-1
awarded by
VANDERBILT UNIVERSITY MEDICAL CENTER ^
Investigator On
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure - Project 3 = HDAC-Mediated Regulation of Endothelin and Nitric Oxide
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure - Research Supplement to Promote Diversity
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Interdisciplinary Training in Kidney-Related Research
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
Kidney Undergraduate Research Experience (KURE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedOctoral Phd and MD Research Training In TEams (PROmoTE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
PRedoctoral Interdisciplinary Training in Renal Physiology and MEdIcIne (PRIME)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
UAB Center for Clinical and Translational Science (CCTS) (3 Linked Awards UL1, KL2, TL1)
awarded by
National Center for Advancing Translational Sciences/NIH/DHHS
Background
Education And Training
Doctor of Philosophy in Physiology/Human and Animal,
Medical College of Wisconsin
2010
Contact
Full Name
Carmen
De Miguel