Neurodegeneration and Experimental Therapeutics (CNET)

Center

People

Faculty Administrative Position

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    Erik Roberson, Director/ UAB Ctr for Neurodegeneration and Experimental Therapeutics

    Dr. Roberson is a neurologist and neuroscientist whose research is focused on age-related neurodegenerative disorders. He received his A.B. with highest honors from Princeton University, then earned his Ph.D in neuroscience and M.D. with high honors at Baylor College of Medicine where he studied molecular mechanisms of learning and memory. He completed a residency in neurology at the University of California San Francisco, where he also served as Chief Resident in Neurology. After residency, he ...

  • Center Members - Faculty

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    Andrew Arrant, Associate Scientist (C)

    Dr. Arrant graduated with a B.S. in Toxicology from the University of Louisiana at Monroe in 2007. He then entered the Integrated Toxicology and Environmental Health Program at Duke University, and in 2012 earned a PhD in Pharmacology in the laboratory of Dr. Cynthia Kuhn. In 2013, Dr. Arrant joined the laboratory of Dr. Erik Roberson at the University of Alabama at Birmingham for postdoctoral training with mouse models of frontotemporal dementia. Dr. Arrant was promoted to a Scientist position ...

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    Andrew Pickering, Associate Scientist (C)

    The Pickering lab is interested in the role of proteostasis, particularly the proteasome in aging and neurodegenerative diseases. Proteostasis is critical for a wide range of neuronal and non-neuronal functions. As we get older many of these proteostatic functions decline. This is even greater in Alzheimer's and Parkinson's disease. We've found that prevention of neuronal proteostatic decline (both both drug and pharmacologic) can extend animal lifespan and protect against age-related cognitive ...

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    Anthony Nicholas, Scientist (C)

    Dr. Nicholas is originally from Pennsylvania and graduated magna cum laude in 1982 with a B.S. degree in Biology from the University of Scranton. He then received his Ph.D. in Anatomy from the Graduate School of Biomedical Sciences in Galveston in 1987, and his M.D. degree from the University of Texas Medical Branch at Galveston in 1990. After medical school, Dr. Nicholas spent two years completing a post-doctoral fellowship in Neuroscience with Dr. Tomas Hökfelt at the Karolinska Institute in S...

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    Ashley Harms, Associate Scientist (C)

    My lab's overall research goal is to understand and investigate the cellular and immunological mechanisms underlying the initiation and progression of synucleinopathy disorders. Specifically, my lab research focuses on how the protein alpha-synuclein contributes to microglial activation, peripheral immune cell infiltration, and subsequent activation of the immune response in Parkinson disease (PD) and Multiple System Atrophy (MSA) models. In the lab we work with multiple immune cell types, incl...

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    Briana De Miranda, Associate Scientist (C)

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    Brittany Lasseigne, Associate Scientist (C)

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    Bruce Korf M.D., Ph.D., Senior Scientist (C)

    Dr. Korf is Wayne H. and Sara Crews Finley Endowed Chair in Medical Genetics, Associate Dean for Genomic Medicine, UAB School of Medicine, Chief Genomics Officer, UAB Medicine and Co-Director of the UAB-HudsonAlpha Center for Genomic Medicine. He is a medical geneticist, pediatrician, and child neurologist, certified by the American Board of Medical Genetics (clinical genetics, clinical cytogenetics, clinical molecular genetics), American Board of Pediatrics, and American Board of Psychiatry an...

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    Constanza Cortes Rodriguez, Associate Scientist (C)

    Our lab is interested in understanding how our brain ages, and in particular, how it ages as an integrated part of a physiological system. We take a cutting edge approach to understanding brain plasticity and brain aging, examining how distant tissues such as skeletal muscle may be fundamentally influencing the rate at which our brain ages. Importantly, as these conversations may be disrupted in age-associated neurodegenerative diseases such as Alzheimer’s disease, we aim to uncover and develop ...

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    David Knight, Associate Scientist (C)

    Dr. Knight’s laboratory is focused on better understanding the neural substrates of human learning, memory, and emotion using magnetic resonance imaging (MRI) techniques that include functional MRI, diffusion tensor imaging, and magnetic resonance spectroscopy. Behavioral and MRI studies from the lab investigate questions that are important for understanding healthy, as well as dysfunctional, emotion processes.

    Recent work from the Knight lab has investigated the neural circuitry that ...

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    David Standaert, Senior Scientist (C)

    Dr. Standaert was named the John N. Whitaker Professor & Chair of Neurology in 2012. Prior to that, he was appointed the John T. and Juanelle D. Strain Endowed Chair by the Board of Trustees of the University of Alabama system, which he held for five years. He received his M.D. and Ph.D. degrees from Washington University in St. Louis in medicine and pharmacology in 1988. He completed a one-year internship in medicine at Jewish Hospital of St. Louis in 1989 and a three-year neurology residency i...

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    Erik Roberson, Associate Scientist (C)

    Dr. Roberson is a neurologist and neuroscientist whose research is focused on age-related neurodegenerative disorders. He received his A.B. with highest honors from Princeton University, then earned his Ph.D in neuroscience and M.D. with high honors at Baylor College of Medicine where he studied molecular mechanisms of learning and memory. He completed a residency in neurology at the University of California San Francisco, where he also served as Chief Resident in Neurology. After residency, he ...

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    Farah Lubin, Associate Scientist (C)

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    Guy Caldwell, Scientist (C)

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    Harrison Walker, Scientist (C)

    Deep brain stimulation (DBS) is more effective than medications and other conventional therapies for motor symptoms of Parkinson's disease, dystonia, and essential tremor. Emerging DBS technologies such as directional and closed loop stimulation have substantial potential to improve a variety of patient outcomes. However these devices are increasingly adaptable and complex, and we lack robust tools to fully realize their therapeutic potential. Dr. Walker's lab investigates how deep brain stimula...

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    Haydeh Payami, Senior Scientist (C)

    Dr. Payami is the founder and Lead Investigator of the NeuroGenetics Research Consortium, a collaborative effort since 1992, formalized in 2004 as a Michael J Fox Foundation Global Genetics Consortium. Dr. Payami received her PhD in Genetics from UC Berkeley. She was a faculty member at the Oregon Health Sciences for 15 years, during which she developed independently-funded research program in Alzheimer and Parkinson genetics, won teaching awards for graduate and medical courses, and served as...

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    Inga Kadisha, Associate Scientist (C)

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    James Wyss, Senior Scientist (C)

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    Jeremy Herskowitz, Associate Scientist (C)

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    Jianhua Zhang Ph.D., Associate Scientist (C)

    The Zhang Lab is seeking a postdoctoral scholar and a graduate student or a MSTP student. We are a very collegial and diverse group working on exciting new research integration of autophagy, metabolism and redox signaling in the nervous system in the context of cardiovascular and neurodegenerative diseases at the Department of Pathology in University of Alabama at Birmingham.

    Attributes:
    Interested, passionate, and dedicated to design and perform interesting and important research<...

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    Joel Glasgow, Scientist (C)

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    John Hartman IV M.D., Associate Scientist (C)

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    John Shacka, Associate Scientist (C)

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    Karen Gamble, Associate Scientist (C)

    The overall goal of my research program is to investigate environmental modulation of circadian clock function in mammalian systems and the contribution of clock disruption to pathological disease. One of the most exciting discoveries that has emerged in recent years is that the circadian molecular clock regulates excitability in neurons that are spontaneously active in the absence of synaptic input. Although the intrinsic 24-h rhythm in membrane properties of neurons of the suprachiasmatic nucl...

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    Karen Jaunarajs, Associate Scientist (C)

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    Kim Caldwell, Scientist (C)

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    Laura Volpicelli-Daley, Associate Scientist (C)

    Biographical Sketch

    I grew up in Albuquerque, NM, and studied Math and English Literature in college. My PhD in Neuroscience was earned at Emory University in the lab of Allan Levey, MD, PhD expert in Alzheimer’s disease and dementias. I also trained in Cell Biology at Yale University and Neurodegenerative disease at the University of Pennsylvania.

    Now, I am an Associate Professor in Neurology with tenure at the University of Alabama at Birmingham (UAB), and proud to be s...

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    Leon Dure, Scientist (C)

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    Mariangela Scarduzio, Associate Scientist (C)

    I am an Instructor at UAB, Department of Neurology, working on genetic mouse models of isolated dystonia

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    Matthew Alexander, Scientist (C)

    Dr. Alexander earned his PhD in Genetics and Developmental Biology in the laboratory of Dr. Daniel Garry at the University of Texas Southwestern Medical Center at Dallas. His graduate training focused on the characterization of forkhead transcription factors in skeletal muscle and cardiac progenitor cells. He moved to Boston in 2008 to join the laboratory of Dr. Louis Kunkel as a postdoctoral fellow where he focused on characterizing the role of non-coding RNAs in skeletal muscle diseases. He wa...

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    Matthew Goldberg, Scientist (C)

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    Michelle Gray, Scientist (C)

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    Natividad Stover, Associate Scientist (C)

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    Oleg Gorbatyuk, Associate Scientist (C)

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    Peter King M.D., Senior Scientist (C)

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    Ping Zhang, Senior Scientist (C)

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    Rajesh Kana, Associate Scientist (C)

    Dr. Kana has several years of experience in research in the field of autism spectrum disorders. After earning PhD from Indian Institute of Technology (IIT), Delhi, India, he completed his postdoctoral training at Carnegie Mellon University. In 2001 he was awarded the William Fulbright pre-doctoral research fellow to do research at University of California Los Angeles. He joined UAB in 2007.

    Dr. Kana is the director of the Cognition, Brain and Autism Laboratory at UAB, and the co-directo...

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    Ray Watts, Senior Scientist (C)

    Ray L. Watts, M.D., UAB's seventh president, has demonstrated visionary leadership in education, research and patient care throughout his career.

    A Birmingham native and graduate of West End High School, Dr. Watts earned a bachelor’s degree in engineering at UAB in 1976. The collaborations he had with biomedical engineering students as an undergraduate sparked an interest in medicine and, four years later, he graduated from Washington University School of Medicine in St. Louis as valed...

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    Richard Kennedy, Scientist (C)

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    Richard Powers, Senior Scientist (C)

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    Ronald Lazar, Senior Scientist (C)

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    Scott Wilson Ph.D., Scientist (C)

    Scott M Wilson PhD
    Associated Professor
    Department of Neurobiology

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    Shinichi Kano, Scientist (C)

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    Shu Chen, Senior Scientist (C)

    Dr. Chen is a neuroscientist whose research is focused on neurodegenerative diseases including prion disease, Alzheimer's disease, Lewy body dementia, and Parkinson's disease. He received his Ph.D. in biochemical pharmacology from the State University of New York at Buffalo in 1993. Before coming to UAB in 2021, he was a Professor of Pathology at the Case Western Reserve University School of Medicine.

    Dr. Chen's laboratory investigates pathogenic mechanisms underlying neurodegenerative ...

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    Syed Shaida Andrabi, Scientist (C)

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    Talene Yacoubian, Scientist (C)

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    William Britt M.D., Senior Scientist (C)

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    Yu-Hua Fang, Scientist (C)

    Yu-Hua Dean Fang, PhD is currently an Associate Professor of Radiology and adjunct faculty of Neurology in University of Alabama at Birmingham. His research is focused on image quantification and analysis. A major field of application is on the kinetic modeling analysis for PET imaging. He has also been extensively involved in image processing of CT, MR and SPECT while the clinical areas include Neurology, Oncology and Cardiology. He recently joined UAB Radiology in September, 2019 and aims to e...

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    Yuhua Song Ph.D., Scientist (C)

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