Selected Publications

Academic Article

Year Title Altmetric
2023 Angiotensin (1-7) Delivered Orally via Probiotic in Combination With Exercise: Sex-Dependent Influence on Health Span 2023
2022 Preserving independence among under-resourced older adults in the Southeastern United States: existing barriers and potential strategies for researchInternational Journal for Equity in Health.  21. 2022
2022 Twelve Months of Time-Restricted Feeding Improves Cognition and Alters Microbiome Composition Independent of Macronutrient CompositionNutrients.  14. 2022
2022 Influence of Aging, Macronutrient Composition and Time-Restricted Feeding on the Fischer344 x Brown Norway Rat Gut MicrobiotaNutrients.  14. 2022
2022 Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer's diseaseActa Pharmaceutica Sinica B.  12:511-531. 2022
2022 A Neuroscience Primer for Integrating Geroscience with the Neurobiology of Aging 2022
2022 Bridging the Gap: A Geroscience Primer for Neuroscientists with Potential Collaborative Applications 2022
2022 Probiotic Releasing Angiotensin (1-7) in a Drosophila Model of Alzheimer's Disease Produces Sex-Specific Effects on Cognitive FunctionJournal of Alzheimer's Disease.  85:1205-1217. 2022
2022 Reuniting the Body "neck Up and Neck Down" to Understand Cognitive Aging: The Nexus of Geroscience and Neuroscience 2022
2021 Modeling AD-related metabolic impairments in the TgF344-AD rat modelAlzheimer's and Dementia.  17:e058576. 2021
2021 A "gut Feeling" to Create a 10th Hallmark of Aging 2021
2021 University of Alabama at Birmingham Nathan Shock Center: comparative energetics of agingGeroscience.  43:2149-2160. 2021
2020 Angiotensin (1–7) delivered orally via probiotic, but not subcutaneously, benefits the gut-brain axis in older ratsGeroscience.  42:1307-1321. 2020
2020 Prevalence of Hospital-Associated Disability in Older Adults: A Meta-analysis 2020
2020 Crosstalk Between the Gut Microbiome and Bioactive Lipids: Therapeutic Targets in Cognitive FrailtyFrontiers in Nutrition.  7. 2020
2020 Bring Back the Rat! 2020
2020 Angiotensin Converting Enzyme Inhibitors Combined with Exercise for Hypertensive Seniors (The ACES Trial): Study Protocol of a Randomized Controlled TrialFrontiers in Medicine.  6. 2020
2020 Effects of aging and life-long moderate calorie restriction on IL-15 signaling in the rat white adipose tissueEuropean Review for Medical and Pharmacological Sciences.  24:2738-2749. 2020
2020 Introduction: Special issue on Aging Science Talks: Science for our community during isolationTranslational Medicine of Aging.  4:149-150. 2020
2020 Maintaining a scientific community while social distancingTranslational Medicine of Aging.  4:55-59. 2020
2020 The gut microbiome as a therapeutic target for cognitive impairment 2020
2020 Therapeutic delivery of ang(1-7) via genetically modified probiotic: A dosing study 2020
2019 Geriatric Care Boot Camp Series: Interprofessional education for a new training paradigm: Geriatric Care Boot Camp SeriesGeriatric Nursing.  40:579-583. 2019
2019 Lipotoxicity, aging, and muscle contractility: does fiber type matter?Geroscience.  41:297-308. 2019
2019 Multimodal intervention to improve functional status in hypertensive older adults: A pilot randomized controlled trialJournal of Clinical Medicine.  8. 2019
2018 Administration of enalapril started late in life attenuates hypertrophy and oxidative stress burden, increases mitochondrial mass, and modulates mitochondrial quality control signaling in the rat heartBiomolecules.  8. 2018
2018 Oestradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in ratsJournal of Neuroendocrinology.  30. 2018
2018 ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old ratsExperimental Gerontology.  111:133-140. 2018
2018 Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss 2018
2018 Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heartFree Radical Biology and Medicine.  124:447-453. 2018
2018 Composition and richness of the serum microbiome differ by age and link to systemic inflammationGeroscience.  40:257-268. 2018
2018 The Antiepileptic Ketogenic Diet Alters Hippocampal Transporter Levels and Reduces Adiposity in Aged Rats 2018
2018 Persistent injury-associated anemia in aged ratsExperimental Gerontology.  103:63-68. 2018
2018 iBAT sympathetic innervation is not required for body weight loss induced by central leptin delivery 2018
2018 Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reductionCanadian Journal of Physiology and Pharmacology.  96:308-312. 2018
2017 Differential physiological responses to central leptin overexpression in male and female ratsJournal of Neuroendocrinology.  29. 2017
2017 Applying theories of adult learning in developing online programs in gerontologyJournal of Adult and Continuing Education.  23:197-205. 2017
2017 Intestinal Permeability Biomarker Zonulin is Elevated in Healthy Aging 2017
2017 Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restrictionCanadian Journal of Physiology and Pharmacology.  95:206-214. 2017
2016 Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change stat3 signalling or SIRT01/AMPK pathway 2016
2016 Comparative Approaches to Understanding the Relation between Aging and Physical Function 2016
2016 Anorexic response to rapamycin does not appear to involve a central mechanismClinical and Experimental Pharmacology and Physiology.  43:802-807. 2016
2016 Antihypertensive use and the effect of a physical activity intervention in the prevention of major mobility disability among older adults: The LIFE study 2016
2016 Rapamycin normalizes serum leptin by alleviating obesity and reducing leptin synthesis in aged rats 2016
2016 Rapamycin versus intermittent feeding: Dissociable effects on physiological and behavioral outcomes when initiated early and late in life 2016
2016 Skeletal muscle fiber analysis by atmospheric pressure scanning microprobe matrix-assisted laser desorption/ionization mass spectrometric imaging at high mass and high spatial resolutionProteomics.  16:1822-1824. 2016
2016 Onset of leptin resistance shows temporal differences related to dose or pulsed treatmentEuropean Journal of Pharmacology.  779:177-185. 2016
2016 High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function 2016
2015 Successful aging: Advancing the science of physical independence in older adultsAgeing Research Reviews.  24:304-327. 2015
2015 Multi-modal intervention to reduce cardiovascular risk among hypertensive older adults: Design of a randomized clinical trialContemporary Clinical Trials.  43:237-242. 2015
2015 Metabolomic analysis of oxidative and glycolytic skeletal muscles by matrix-assisted laser desorption/ionizationmass spectrometric imaging (MALDI MSI)Journal of the American Society for Mass Spectrometry.  26:915-923. 2015
2015 Geriatric care boot camp: An interprofessional education program for healthcare professionalsJournal of the American Geriatrics Society.  63:997-1001. 2015
2015 The renin–angiotensin system and prevention of age-related functional decline: where are we now?Geroscience.  37:1-11. 2015
2014 Genetic influence on exercise-induced changes in physical function among mobility-limited older adultsPhysiological Genomics.  46:149-158. 2014
2014 Battery of behavioral tests in mice that models age-associated changes in human motor functionGeroscience.  36:583-595. 2014
2014 Thermal sensitivity across ages and during chronic fentanyl administration in ratsPsychopharmacology.  231:75-84. 2014
2013 Relationships of isometric mid-thigh pull variables to weightlifting performance 2013
2013 Late-life Enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscleGeroscience.  35:1061-1075. 2013
2012 Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344×Brown Norway male ratsGeroscience.  34:831-843. 2012
2012 Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exerciseJournal of the American Geriatrics Society.  60:1244-1252. 2012
2012 Effects of morphine on thermal sensitivity in adult and aged rats 2012
2012 Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia 2012
2011 Interleukin-6, C-reactive protein, and tumor necrosis factor-alpha as predictors of mortality in frail, community-living elderly individualsJournal of the American Geriatrics Society.  59:1679-1685. 2011
2011 Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidneyExperimental Gerontology.  46:542-548. 2011
2011 Erratum to: Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 x Brown Norway rats (Age DOI: 10.1007/s11357-010-9196-y)Geroscience.  33:185. 2011
2011 The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats 2011
2011 Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesityEuropean Journal of Neuroscience.  33:1541-1550. 2011
2011 Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 x Brown Norway ratsGeroscience.  33:167-183. 2011
2011 Effects of chronic fentanyl administration on physical performance of aged ratsExperimental Gerontology.  46:65-72. 2011
2011 Protection against age-dependent renal injury in the F344xBrown Norway male rat is associated with maintained nitric oxide synthaseMechanisms of Ageing and Development.  132:1-7. 2011
2010 Beneficial effects of a Q-terh® based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in ratsPLoS One.  5. 2010
2010 Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesityNeuroscience.  169:1662-1671. 2010
2010 Effects of age on thermal sensitivity in the rat 2010
2010 Myeloperoxidase levels and mortality in frail community-living elderly individuals 2010
2010 Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy 2010
2010 Models of accelerated sarcopenia: Critical pieces for solving the puzzle of age-related muscle atrophyAgeing Research Reviews.  9:369-383. 2010
2009 Cellular Mechanisms of Cardioprotection by Calorie Restriction: State of the Science and Future PerspectivesClinics in Geriatric Medicine.  25:715-732. 2009
2009 Influence of calorie restriction on measures of age-related cognitive decline: Role of increased physical activity 2009
2009 Rapamycin fed late in life extends lifespan in genetically heterogeneous miceNature.  460:392-395. 2009
2009 Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with agingAging Cell.  8:178-191. 2009
2009 Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restrictionMechanisms of Ageing and Development.  130:272-280. 2009
2009 Molecular inflammation: Underpinnings of aging and age-related diseasesAgeing Research Reviews.  8:18-30. 2009
2008 Evaluation of Prescription Opioids Using Operant-Based Pain Measures in RatsExperimental and Clinical Psychopharmacology.  16:367-375. 2008
2008 Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity 2008
2008 Iron accumulation with age, oxidative stress and functional declinePLoS One.  3. 2008
2008 Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning abilityExperimental Neurology.  211:141-149. 2008
2008 Effects of short-term GH supplementation and treadmill exercise training on physical performance and skeletal muscle apoptosis in old rats 2008
2008 Role of the renin-angiotensin system in age-related sarcopenia and diastolic dysfunctionAging Health.  4:37-46. 2008
2007 Molecular mechanisms of life- And health-span extension: Role of calorie restriction and exercise intervention 2007
2007 Anabolic effects of testosterone are preserved during inhibition of 5α-reductase 2007
2007 Lifelong caloric restriction and interleukin-6 secretion from adipose tissue: Effects on physical performance decline in aged rats 2007
2006 Effects of caloric restriction and exercise on age-related, chronic inflammation assessed by C-reactive protein and interleukin-6 2006
2006 Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats 2006
2006 Physical exercise and comorbidity. Results from the Fitness and Arthritis in Seniors Trial (FAST)Aging Clinical and Experimental Research.  18:374-380. 2006
2005 Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systemsPhysiological Genomics.  23:311-317. 2005
2005 Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span 2005
2005 Angiotensin-converting enzyme inhibition intervention in elderly persons: Effects on body composition and physical performance 2005
2005 Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive agingAgeing Research Reviews.  4:195-212. 2005
2004 Growth hormone treatment attenuates age-related changes in hippocampal short-term plasticity and spatial learningNeuroscience.  129:119-127. 2004
2004 Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats 2004
2004 Hemoglobin Levels and Skeletal Muscle: Results from the InCHIANTI Study 2004
2002 A critical analysis of the role of growth hormone and IGF-1 in aging and lifespanTrends in Genetics.  18:295-301. 2002
2002 Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: An observational study 2002
2002 Models of growth hormone and IGF-1 deficiency: Applications to studies of aging processes and life-span determination 2002
2002 Physical performance and longevity in aged rats 2002
2001 Assessment of physical function in aging rodents: A strategy for improving preclinical testingExperimental Aging Research.  27:271-282. 2001
1998 Development of cholinergic neurons in rat brain regions: Dose-dependent effects of propylthiouracil-induced hypothyroidismNeurotoxicology and Teratology.  20:627-635. 1998
1995 Early Cerebellar Lesions Impair Eyeblink Conditioning in Developing Rats: Differential Effects of Unilateral Lesions on Postnatal Day 10 or 20Behavioral Neuroscience.  109:893-902. 1995
1995 Neonatal medial prefrontal lesions and recovery of spatial delayed alternation in the Rat: Effects of delay intervalDevelopmental Psychobiology.  28:269-279. 1995
1995 Ontogeny of eyeblink conditioning in the rat: Auditory frequency and discrimination learning effectsDevelopmental Psychobiology.  28:307-320. 1995


Year Title Altmetric
2005 Growth Hormone, Insulin-Like Growth Factor-1, and the Biology of Aging.  534-569. 2005

Education And Training

  • Doctor of Philosophy in Psychology, University of North Carolina System : Chapel Hill 1992
  • Full Name

  • Christy Carter