Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Sympathetic innervation of human and porcine spleens: implications for between species variation in function.Bioelectronic Medicine.  8:20. 2022
2022 COVID-19 and Long-Term Outcomes: Lessons from Other Critical Care Illnesses and Potential MechanismsAmerican Journal of Respiratory Cell and Molecular Biology.  67:275-283. 2022
2022 Pulmonary Endothelial Tau Aggregation After Infection 2022
2022 ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during Pseudomonas aeruginosa InfectionToxins.  14. 2022
2022 Cytotoxic tau released from lung microvascular endothelial cells upon infection with Pseudomonas aeruginosa promotes neuronal tauopathyJournal of Biological Chemistry.  298. 2022
2021 Carbonic anhydrase ix and hypoxia promote rat pulmonary endothelial cell survival during infectionAmerican Journal of Respiratory Cell and Molecular Biology.  65:630-645. 2021
2021 The role of pseudomonas aeruginosa virulence factors in cytoskeletal dysregulation and lung barrier dysfunctionToxins.  13. 2021
2021 Fibrinolytic or anti-plasmin (nafamostat) therapy for COVID-19: A timing challenge for cliniciansPulmonary Pharmacology and Therapeutics.  70. 2021
2021 Phosphodiesterase 4 mediates interleukin-8-induced heterologous desensitization of the β2-adrenergic receptor 2021
2021 Pneumonia initiates a tauopathy 2021
2021 Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier 2021
2021 Estrogen Alleviates Sex-Dependent Differences in Lung Bacterial Clearance and Mortality Secondary to Bacterial Pneumonia after Traumatic Brain InjuryJournal of Neurotrauma.  38:989-999. 2021
2020 Autonomic nervous system activity and the risk of nosocomial infection in critically ill patients with brain injuryIntensive Care Medicine Experimental.  8. 2020
2020 Role of angiotensin converting enzyme 2 and pericytes in cardiac complications of 5 COVID-19 infection 2020
2020 a-tocopherol attenuates the severity of pseudomonas aeruginosa-induced pneumoniaAmerican Journal of Respiratory Cell and Molecular Biology.  63:234-243. 2020
2020 Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions 2020
2020 Exoenzyme y contributes to end-organ dysfunction caused by pseudomonas aeruginosa pneumonia in critically ill patients: An exploratory studyToxins.  12. 2020
2020 Neuronal Wiskott-Aldrich syndrome protein regulates Pseudomonas aeruginosa-induced lung vascular permeability through the modulation of actin cytoskeletal dynamics 2020
2020 An ounce of prevention may prevent hospitalizationPhysiological Reviews.  100:1347-1348. 2020
2019 Infection-induced endothelial amyloids impair memory 2019
2019 Erratum: Correction: Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental study (PLoS Med (2018) 15:3 (e1002522) DOI: 10.1371/journal.pmed.1002522)PLoS Medicine.  16. 2019
2018 Nosocomial pneumonia elicits an endothelial proteinopathy: Evidence for a source of neurotoxic amyloids in critically ill patientsAmerican Journal of Respiratory and Critical Care Medicine.  198:1575-1578. 2018
2018 Low Plasma ADAMTS13 Activity Is Associated with Coagulopathy, Endothelial Cell Damage and Mortality after Severe Paediatric TraumaThrombosis and Haemostasis.  118:676-687. 2018
2018 Role of heme in lung bacterial infection after trauma hemorrhage and stored red blood cell transfusion: A preclinical experimental studyPLoS Medicine.  15. 2018
2018 Histone-Complexed DNA Fragments Levels are Associated with Coagulopathy, Endothelial Cell Damage, and Increased Mortality after Severe Pediatric TraumaShock.  49:44-52. 2018
2017 Pseudomonas aeruginosa infection liberates transmissible, cytotoxic prion amyloids 2017
2017 Acute brain trauma, lung injury, and pneumonia: More than just altered mental status and decreased airway protection 2017
2016 Neuronal Wiskott-Aldrich syndrome protein regulates TGF-β1-mediated lung vascular permeability 2016
2016 The glycocalyx and trauma: A reviewShock.  45:338-348. 2016
2016 Regulation of n-formyl peptide receptor signaling and trafficking by arrestin-src kinase interactionPLoS One.  11. 2016
2015 Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhageFree Radical Biology and Medicine.  85:207-218. 2015
2015 Synergistic Inhibition of β2-adrenergic Receptor-mediated Alveolar Epithelial Fluid Transport by Interleukin-8 and Transforming Growth Factor-βAnesthesiology.  122:1084-1092. 2015
2014 Postexposure aerosolized heparin reduces lung injury in chlorine-exposed mice 2014
2014 A more clinically relevant model of ventilator-associated pneumonia?Anesthesiology.  120:1075-1077. 2014
2014 Heat-shock response increases lung injury caused by pseudomonas aeruginosa via an Interleukin-10-dependent mechanism in miceAnesthesiology.  120:1450-1462. 2014
2013 Protein C and acute inflammation: A clinical and biological perspective 2013
2013 HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1PLoS One.  8. 2013
2009 Adaptor protein-2 interaction with arrestin regulates GPCR recycling and apoptosisTraffic.  10:1286-1300. 2009
2009 Hemorrhagic colitis secondary to acute elemental mercury vapor poisoningAmerican Journal of Gastroenterology.  104:530-531. 2009
2007 Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replicationDNA Repair.  6:797-808. 2007
2005 Inhibition of chemoattractant N-formyl peptide receptor trafficking by active arrestinsTraffic.  6:87-99. 2005
2002 XRCC3 controls the fidelity of homologous recombination: Roles for XRCC3 in late stages of recombinationMolecular Cell.  10:387-395. 2002
2001 Overexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cellsNucleic Acids Research.  29:4352-4360. 2001
2000 Inhibition of ferric chelate reductase in alfalfa roots by Cobalt, Nickel, Chromium, and CopperJournal of Plant Nutrition.  23:1833-1845. 2000
1999 Treatment of waste containing EDTA by chemical oxidationWaste Management.  19:477-482. 1999

Education And Training

  • Doctor of Medicine, University of New Mexico 2009
  • Doctor of Philosophy in Biomedical Sciences, University of New Mexico 2008
  • Full Name

  • Brant Wagener