• Carolyn Bolton Moore is a South African physician who has been living and working in Zambia since 2004. She has a keen interest in prevention of mother to child transmission interventions and has 15 years experience treating HIV-infected adults and children in Africa. She has worked on NIH funded paediatric clinical research projects since 2002, initially at the PHRU in Johannesburg, South Africa and, since 2004 at the CIDRZ CRS in Lusaka, Zambia. For the past 11 years, she has combined paediatric HIV research with program implementation within the Zambian public health system. Presently she is an Assistant Professor in the Department of Medicine at UAB and the Chief Medical Officer at the Centre for Infectious Disease Research in Zambia (CIDRZ). She completed her masters in epidemiology through the London School of Hygiene and Tropical Medicine in 2011. Currently she serves as the CRS Site Leader in Zambia and the protocol Co Chair for IMPAACT 1070, a phase I/II study.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 Cervical cancer screening outcomes in Zambia, 2010–19: a cohort study 2021
    2021 Patterns and Predictors of Incident Return to HIV Care Among Traced, Disengaged Patients in Zambia: Analysis of a Prospective Cohort 2021
    2021 Profiles of HIV Care Disruptions Among Adult Patients Lost to Follow-up in Zambia: A Latent Class Analysis 2021
    2020 Characteristics and outcomes of adolescents living with perinatally acquired HIV within Southern AfricaAIDS.  34:2275-2284. 2020
    2020 Longitudinal care cascade outcomes among people eligible for antiretroviral therapy who are newly linking to care in Zambia: A multistate analysisClinical Infectious Diseases.  71:E561-E570. 2020
    2020 Understanding patient transfers across multiple clinics in Zambia among HIV infected adultsPLoS One.  15. 2020
    2020 Participation in adherence clubs and on-time drug pickup among HIV-infected adults in Zambia: A matched-pair cluster randomized trialPLoS Medicine.  17. 2020
    2020 Patient-reported reasons for declining same-day antiretroviral therapy initiation in routine HIV care settings in Lusaka, Zambia: results from a mixed-effects regression analysisJournal of the International AIDS Society.  23. 2020
    2020 Mortality estimates by age and sex among persons living with HIV after ART initiation in Zambia using electronic medical records supplemented with tracing a sample of lost patients: A cohort studyPLoS Medicine.  17. 2020
    2020 Redefining and revisiting cost estimates of routine ART care in Zambia: an analysis of ten clinicsJournal of the International AIDS Society.  23. 2020
    2020 Association of virologic failure and nonnucleoside reverse transcriptase inhibitor resistance found in antiretroviral-naive children infected with human immunodeficiency virus and given efavirenz-based treatmentJournal of the Pediatric Infectious Diseases Society.  9:261-264. 2020
    2019 Human-Centered Design Lessons for Implementation Science: Improving the Implementation of a Patient-Centered Care Intervention 2019
    2019 Accurate dried blood spots collection in the community using non-medically trained personnel could support scaling up routine viral load testing in resource limited settingsPLoS One.  14. 2019
    2019 A Review of Differentiated Service Delivery for HIV Treatment: Effectiveness, Mechanisms, Targeting, and ScaleCurrent HIV/AIDS Reports.  16:324-334. 2019
    2019 Differentiated Care Preferences of Stable Patients on Antiretroviral Therapy in Zambia: A Discrete Choice Experiment 2019
    2019 Establishing Dosing Recommendations for Efavirenz in HIV/TB-Coinfected Children Younger Than 3 Years 2019
    2019 Retention and viral suppression in a cohort of HIV patients on antiretroviral therapy in Zambia: Regionally representative estimates using a multistage-sampling-based approachPLoS Medicine.  16. 2019
    2019 Operational characteristics of antiretroviral therapy clinics in Zambia: A time and motion analysisBMC Health Services Research.  19. 2019
    2019 Correction: Retention and viral suppression in a cohort of HIV patients on antiretroviral therapy in Zambia: Regionally representative estimates using a multistage-sampling-based approach (PLoS Medicine (2019) 16:5 (e1002811) DOI: 10.1371/journal.pmed.1002811)PLoS Medicine.  16. 2019
    2019 Longitudinal engagement trajectories and risk of death among new ART starters in Zambia: A group-based multi-trajectory analysisPLoS Medicine.  16. 2019
    2018 Application of a Multistate Model to Evaluate Visit Burden and Patient Stability to Improve Sustainability of Human Immunodeficiency Virus Treatment in ZambiaClinical Infectious Diseases.  67:1269-1277. 2018
    2018 Understanding preferences for HIV care and treatment in Zambia: Evidence from a discrete choice experiment among patients who have been lost to follow-upPLoS Medicine.  15. 2018
    2018 Estimating the real-world effects of expanding antiretroviral treatment eligibility: Evidence from a regression discontinuity analysis in ZambiaPLoS Medicine.  15. 2018
    2018 Improved Retention with 6-Month Clinic Return Intervals for Stable Human Immunodeficiency Virus-Infected Patients in ZambiaClinical Infectious Diseases.  66:237-243. 2018
    2018 Estimated mortality on HIV treatment among active patients and patients lost to follow-up in 4 provinces of Zambia: Findings from a multistage sampling-based surveyPLoS Medicine.  15. 2018
    2017 CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infectionAIDS.  31:1129-1136. 2017
    2017 Patient engagement in HIV care and treatment in Zambia, 2004–2014Tropical Medicine and International Health.  22:332-339. 2017
    2016 Association between hepatitis B co-infection and elevated liver stiffness among HIV-infected adults in Lusaka, ZambiaTropical Medicine and International Health.  21:1435-1441. 2016
    2016 Liver fibrosis in treatment-naïve HIV-infected and HIV/HBV co-infected patients: Zambia and Switzerland comparedInternational Journal of Infectious Diseases.  51:97-102. 2016
    2016 Contraceptive use among HIV-infected women and men receiving antiretroviral therapy in Lusaka, Zambia: A cross-sectional surveyBMC Public Health.  16. 2016
    2016 Hepatitis B infection, viral load and resistance in HIV-infected patients in Mozambique and ZambiaPLoS One.  11. 2016
    2016 Findings from a comprehensive diarrhoea prevention and treatment programme in Lusaka, ZambiaBMC Public Health.  16. 2016
    2015 Pediatric HIV-HBV coinfection in Lusaka, Zambia: Prevalence and short-term treatment outcomesJournal of Tropical Pediatrics.  61:464-467. 2015
    2015 Quality of Care and Service Expansion for HIV Care and TreatmentCurrent HIV/AIDS Reports.  12:223-230. 2015
    2015 HIV and adolescents: Focus on young key populations: FocusJournal of the International AIDS Society.  18. 2015
    2015 Providing comprehensive health services for young key populations: Needs, barriers and gapsJournal of the International AIDS Society.  18:29-40. 2015
    2014 Antiretroviral therapy restores age-dependent loss of resting memory B cells in young HIV-Infected zambian children 2014
    2014 Changes in cellular immune activation and memory T-cell subsets in HIV-infected Zambian children receiving HAART 2014
    2014 Managing multiple funding streams and agendas to achieve local and global health and research objectives: Lessons from the field 2014
    2014 Prognosis of children with HIV-1 infection starting antiretroviral therapy in Southern Africa: A collaborative analysis of treatment programs 2014
    2014 Resource utilization and costs of care prior to ART initiation for pediatric patients in ZambiaAIDS Research and Treatment.  2014. 2014
    2013 Temporal trends in the characteristics of children at antiretroviral therapy initiation in Southern Africa: The IeDEA-SA collaborationPLoS One.  8. 2013
    2013 Changes in measles serostatus among HIV-infected zambian children initiating antiretroviral therapy before and after the 2010 measles outbreak and supplemental immunization activitiesJournal of Infectious Diseases.  208:1747-1755. 2013
    2013 When to Start Antiretroviral Therapy in Children Aged 2-5 Years: A Collaborative Causal Modelling Analysis of Cohort Studies from Southern AfricaPLoS Medicine.  10. 2013
    2013 Prevention of mother-to-child HIV transmission within the continuum of maternal, newborn, and child health servicesCurrent Opinion in HIV and AIDS.  8:498-503. 2013
    2013 Integrating HIV treatment with primary care outpatient services: Opportunities and challenges from a scaled-up model in ZambiaHealth Policy and Planning.  28:347-357. 2013
    2013 Retention in Care and Outpatient Costs for Children Receiving Antiretroviral Therapy in Zambia: A Retrospective Cohort AnalysisPLoS One.  8. 2013
    2013 Immunologic risk factors for early mortality after starting antiretroviral therapy in HIV-Infected Zambian childrenAIDS Research and Human Retroviruses.  29:479-487. 2013
    2013 Nonvirologic algorithms for predicting HIV infection among HIV-exposed infants younger than 12 weeks of age 2013
    2012 Does provider-initiated counselling and testing (PITC) strengthen early diagnosis and treatment initiation? Results from an analysis of an urban cohort of HIV-positive patients in Lusaka, ZambiaJournal of the International AIDS Society.  15. 2012
    2012 Six-month hemoglobin concentration and its association with subsequent mortality among adults on antiretroviral therapy in Lusaka, Zambia 2012
    2012 Evaluation of a task-shifting strategy involving peer educators in HIV care and treatment clinics in Lusaka, ZambiaJournal of Public Health in Africa.  3:8-14. 2012
    2012 Variability of growth in children starting antiretroviral treatment in Southern AfricaPediatrics.  130. 2012
    2011 Comparative outcomes of tenofovir-based and zidovudine-based antiretroviral therapy regimens in Lusaka, Zambia 2011
    2011 Causes of stillbirth, neonatal death and early childhood death in rural Zambia by verbal autopsy assessmentsTropical Medicine and International Health.  16:894-901. 2011
    2011 Opt-out provider-initiated HIV testing and counselling in primary care outpatient clinics in ZambiaBulletin of the World Health Organization.  89:328-333. 2011
    2010 Secular trends in pediatric antiretroviral treatment programs in rural and urban Zambia: A retrospective cohort studyBMC Pediatrics.  10. 2010
    2010 Early clinical and programmatic outcomes with tenofovir-based antiretroviral therapy in Zambia 2010
    2010 Differences in presentation, treatment initiation, and response among children infected with human immunodeficiency virus in urban and rural Zambia 2010
    2009 Causes of morbidity among HIV-infected children on antiretroviral therapy in primary care facilities in Lusaka, ZambiaTropical Medicine and International Health.  14:1190-1198. 2009
    2009 Use of task-shifting to rapidly scale-up HIV treatment services: Experiences from Lusaka, ZambiaBMC Health Services Research.  9. 2009
    2008 Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan AfricaLancet Infectious Diseases.  8:477-489. 2008
    2007 Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in ZambiaJournal of the American Medical Association.  298:1888-1899. 2007
    2005 A randomized trial of two postexposure prophylaxis regimens to reduce mother-to-child HIV-1 transmission in infants of untreated mothersAIDS.  19:1289-1297. 2005
    2005 Feasibility and acceptability of postpartum voluntary counselling and testing (PPVCT) in a large tertiary hospital in the South African settingSouthern African Journal of HIV Medicine.  8-10. 2005

    Principal Investigator On

  • Agreement ISPM & UAB (2021-2023)  awarded by UNIVERSITY OF BERN
  • Better Information for Health in Zambia  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Capacity Building and Strengthening Implementation of HIV Combination Prevention and Treatment Services  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Developing Research Training in Zambia to Address the Epidemic of Cardiovascular Disease and Mental Illness Amongst HIV Infested Population  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia (Efficient Health)  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • IMPAACT Protocol P1070 Co-Chair  awarded by Johns Hopkins University
  • International Epidemiology Databases to Evaluate AIDS - Southern Africa (IeDEA-SA)  awarded by UNIVERSITY OF BERN
  • International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT)  awarded by SOCIAL & SCIENTIFIC SYSTEMS
  • Leveraging Person-Centered Care To Improve HIV Outcomes in Zambia  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Private Grant  awarded by VIIV HEALTHCARE COMPANY
  • Provincial Ownership to Uplift Delivery of HIV/TB Services in Zambia (PROUD-Z) Through Technical Assistance  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Reaching 90 90 90 in Adolescents in Zambia: Using all our SKILLZ  awarded by National Institute of Mental Health/NIH/DHHS
  • Strengthening Quality Improvement through Person Centred Approaches (S-QIP)  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • The VMMC Program and Pilot in Zambia  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Transitional to Local Ownership and Integration of HIV Programs in Primary Health Care (HILO)  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • VMMC Nexus Prime  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ)
  • Education And Training

  • Master's Level Degree in Epidemiology, University of London - London School of Hygiene and Tropical Medicine 2011
  • Bachelor of Medicine & Surgery (MBBS) in Community Health and Preventive Medicine, University of the Witwatersrand 1997
  • Full Name

  • Carolyn Moore