• Brian Casey is originally from Pennsylvania, and earned his Doctor of Medicine degree at Temple University in Philadelphia. He then did his OB/GYN residency training at Saint Barnabas Medical Center in New Jersey and subsequently completed his Maternal-Fetal Medicine training at the University of Texas Southwestern Medical Center.

    Dr. Casey spent 23 years on faculty at Parkland Hospital/UT Southwestern before coming to University of Alabama at Birmingham as Division Director of Maternal Fetal Medicine. He has been a productive clinician-researcher including serving as the Principal Investigator for the Eunice Kennedy-Shriver NICHD Maternal-Fetal Medicine Units Network TSH Trial. This landmark investigation of subclinical hypothyroidism involved screening more than 97,000 pregnant women nationally and a 92% five-year developmental follow-up of their offspring. Dr. Casey recently received the Roy M. Pitkin Award from the American Congress of Obstetricians and Gynecologists for a randomized controlled trial in gestational diabetes and the Norman F. Gant Award for Best Research in Maternal-Fetal Medicine for his work on the TSH Trial.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 Relationship Between Maternal Economic Vulnerability and Childhood Neurodevelopment at 2 and 5 Years of LifeObstetrics and Gynecology.  138:379-388. 2021
    2021 Maternal and Neonatal Outcomes Associated with Amniotomy among Nulliparous Women Undergoing Labor Induction at Term 2021
    2021 A trial of hyperimmune globulin to prevent congenital cytomegalovirus infectionNew England Journal of Medicine.  385:436-444. 2021
    2021 Nifedipine for Acute Tocolysis of Preterm Labor: A Placebo-Controlled Randomized TrialObstetrics and Gynecology.  138:73-78. 2021
    2021 Association of Breastfeeding and Child IQ Score at Age 5 YearsObstetrics and Gynecology.  137:561-570. 2021
    2021 Gestational diabetes - On broadening the diagnosisNew England Journal of Medicine.  384:965-966. 2021
    2021 General anesthesia for cesarean delivery and childhood neurodevelopmental and perinatal outcomes: a secondary analysis of a randomized controlled trialInternational Journal of Obstetric Anesthesia.  45:34-40. 2021
    2021 Maternal and Perinatal Outcomes of Expectant Management of Full-Term, Low-Risk, Nulliparous PatientsObstetrics and Gynecology.  137:250-257. 2021
    2021 Evaluation of Hypoglycemia in Neonates of Women at Risk for Late Preterm Delivery: An Antenatal Late Preterm Steroids Trial Cohort Study 2021
    2021 Head Circumference within the Normal Range and Neurodevelopmental Outcomes in Preterm Infants 2021
    2021 Maternal and Neonatal Outcomes in Nulliparous Participants Undergoing Labor Induction by Cervical Ripening Method 2021
    2020 Customized Probability of Vaginal Delivery With Induction of Labor and Expectant Management in Nulliparous Women at 39 Weeks of GestationObstetrics and Gynecology.  136:698-705. 2020
    2020 Elective Labor Induction at 39 Weeks of Gestation Compared With Expectant Management: Factors Associated With Adverse Outcomes in Low-Risk Nulliparous WomenObstetrics and Gynecology.  136:692-697. 2020
    2020 Outpatient Foley Catheter for Induction of Labor in Nulliparous Women: A Randomized Controlled TrialObstetrics and Gynecology.  136:597-606. 2020
    2020 Lactation versus formula feeding: Insulin, glucose, and fatty acid metabolism during the postpartum periodDiabetes.  69:1624-1635. 2020
    2020 Effect of Thyroxine Therapy on Depressive Symptoms among Women with Subclinical HypothyroidismObstetrics and Gynecology.  135:812-820. 2020
    2020 Effect of Treatment of Mild Gestational Diabetes on Long-Term Maternal Outcomes 2020
    2020 Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19American Journal of Perinatology Reports.  10:E165-E168. 2020
    2020 Hepatitis C Virus Antibody Screening in a Cohort of Pregnant Women: Identifying Seroprevalence and Risk FactorsObstetrics and Gynecology.  135:778-788. 2020
    2020 Association between Features of Spontaneous Late Preterm Labor and Late Preterm Birth 2020
    2020 Maternal Sense of Control During Childbirth and Infant Feeding MethodObstetrics and Gynecology.  135:583-590. 2020
    2020 The relationship of maternal glycemia to childhood obesity and metabolic dysfunction 2020
    2020 Factors Associated with Appropriate Gestational Weight Gain among Women with Obesity 2020
    2020 Fibroblast Growth Factor 21 and Metabolic Dysfunction in Women with a Prior Glucose-Intolerant Pregnancy 2020
    2020 Outcomes before and after Adopting Guidelines for Expectant Management of Severe Preeclampsia 2020
    2019 Closed Incision Negative Pressure Therapy in Morbidly Obese Women Undergoing Cesarean Delivery: A Randomized Controlled TrialObstetrics and Gynecology.  134:781-789. 2019
    2019 Thyroid Function Test Abnormalities during Pregnancy 2019
    2019 Elective Induction of Labor in the 39th Week of Gestation Compared With Expectant Management of Low-Risk Multiparous WomenObstetrics and Gynecology.  134:282-287. 2019
    2019 Association of Gestational Diabetes Mellitus with Neonatal Respiratory MorbidityObstetrics and Gynecology.  133:349-353. 2019
    2019 Cost-effectiveness of Antenatal Corticosteroid Therapy vs No Therapy in Women at Risk of Late Preterm Delivery: A Secondary Analysis of a Randomized Clinical TrialJAMA Pediatrics2019
    2018 Child Neurodevelopmental Outcomes by Prepregnancy Body Mass Index and Gestational Weight GainObstetrics and Gynecology.  132:1386-1393. 2018
    2018 Thyroid function in neonates of women with subclinical hypothyroidism or hypothyroxinemiaJournal of Perinatology.  38:1490-1495. 2018
    2018 Labor induction versus expectant management in low-risk nulliparous womenNew England Journal of Medicine.  379:513-523. 2018
    2018 The FL/AC Ratio for Prediction of Shoulder Dystocia in Women with Gestational DiabetesObstetrical and Gynecological Survey.  73:129-130. 2018
    2018 Pregnancy-associated hypertension and offspring cardiometabolic healthObstetrics and Gynecology.  131:313-321. 2018
    2017 Predictive Characteristics of Elevated 1-Hour Glucose Challenge Test Results for Gestational Diabetes 2017
    2017 The FL/AC ratio for prediction of shoulder dystocia in women with gestational diabetes 2017
    2017 Impact of metabolic acidemia at birth on neonatal outcomes in infants born before 34 weeks’ gestation 2017
    2017 Subclinical hypothyroidism or hypothyroxinemia in pregnancyNew England Journal of Medicine.  377:701. 2017
    2017 Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancyObstetrical and Gynecological Survey.  72:464-465. 2017
    2017 Treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancyNew England Journal of Medicine.  376:815-825. 2017
    2017 Infant outcomes among women with Zika virus infection during pregnancy: results of a large prenatal Zika screening programAmerican Journal of Obstetrics and Gynecology.  216:292.e1-292.e8. 2017
    2017 Pregnancies after the diagnosis of mild gestational diabetes mellitus and risk of cardiometabolic disordersObstetrics and Gynecology.  129:273-280. 2017
    2016 Relationship between Excessive Gestational Weight Gain and Neonatal Adiposity in Women with Mild Gestational Diabetes MellitusObstetrics and Gynecology.  128:1325-1332. 2016
    2016 Antenatal betamethasone for women at risk for late preterm deliveryObstetrical and Gynecological Survey.  71:453-455. 2016
    2016 Antenatal betamethasone for women at risk for late preterm deliveryNew England Journal of Medicine.  374:1311-1320. 2016
    2016 Carpenter-coustan compared with national diabetes data group criteria for diagnosing gestational diabetesObstetrics and Gynecology.  127:893-898. 2016
    2016 Pregnancy-associated hypertension in glucose-intolerant pregnancy and subsequent metabolic syndromeObstetrics and Gynecology.  127:771-779. 2016
    2015 Association of influenza vaccination on decreased stillbirth rate 2015
    2015 Asian women have attenuated sympathetic activation but enhanced renal-adrenal responses during pregnancy compared to Caucasian women 2015
    2015 Mild gestational diabetes mellitus and long-term child healthDiabetes Care.  38:445-452. 2015
    2015 Does maternal body mass index influence treatment effect in women with mild gestational diabetes? 2015
    2015 Glyburide in Women with Mild Gestational Diabetes: A Randomized Controlled TrialObstetrics and Gynecology.  126:303-309. 2015
    2015 Metabolic Acidemia in Live Births at 35 Weeks of Gestation or GreaterObstetrics and Gynecology.  126:279-283. 2015
    2015 ReplyAmerican Journal of Obstetrics and Gynecology.  212:690-691. 2015
    2014 Thyroid screening in pregnancyAmerican Journal of Obstetrics and Gynecology.  211:351-353.e1. 2014
    2014 Inadequate weight gain in overweight and obese pregnant women: What is the effect on fetal growth?American Journal of Obstetrics and Gynecology.  211:137.e1-137.e7. 2014
    2014 Subsequent pregnancy outcomes in women previously diagnosed with subclinical hypothyroidism 2014
    2014 The debate on thyroid screening during pregnancy continuesObstetrics and Gynecology.  124:8-9. 2014
    2013 Customized versus population approach for evaluation of fetal overgrowth 2013
    2013 The obstetric and neonatal implications of a low value on the 50-g glucose screening test 2013
    2012 Perinatal outcomes in hispanic and non-hispanic white women with mild gestational diabetesObstetrics and Gynecology.  120:1099-1104. 2012
    2012 Sympathetic activation during early pregnancy in humans 2012
    2012 Relationship of subclinical thyroid disease to the incidence of gestational diabetesObstetrics and Gynecology.  119:983-988. 2012
    2012 An immunologic basis for placental insufficiency in fetal growth restriction 2012
    2012 Maternal BMI, glucose tolerance, and adverse pregnancy outcomesAmerican Journal of Obstetrics and Gynecology.  207:62.e1-62.e7. 2012
    2012 Subclinical thyroid disease and the incidence of hypertension in pregnancyObstetrics and Gynecology.  119:315-320. 2012
    2011 Subclinical thyroid dysfunction during pregnancyClinical Obstetrics and Gynecology.  54:493-498. 2011
    2011 Thyroid disease in pregnancyClinical Obstetrics and Gynecology.  54:458. 2011
    2011 Glycemic characteristics and neonatal outcomes of women treated for mild gestational diabetesObstetrics and Gynecology.  117:819-827. 2011
    2011 In replyObstetrics and Gynecology.  117:175-176. 2011
    2011 The relationship between maternal glycemia and perinatal outcomeObstetrics and Gynecology.  117:218-224. 2011
    2010 Pregnancy outcomes after orthopedic trauma 2010
    2010 A multicenter, randomized trial of treatment for mild gestational diabetesObstetrical and Gynecological Survey.  65:69-70. 2010
    2010 Diagnostic dilemmas in a pregnant woman with influenza a (H1N1) infectionObstetrics and Gynecology.  115:409-412. 2010
    2010 Prediction of diabetes recurrence in women with class A(Diet-Treated) gestational diabetes 2010
    2010 Pregnancy outcomes in women with thyroid peroxidase antibodiesObstetrics and Gynecology.  116:381-386. 2010
    2009 In replyObstetrics and Gynecology.  114:1375-1376. 2009
    2009 A multicenter, randomized trial of treatment for mild gestational diabetesNew England Journal of Medicine.  361:1339-1348. 2009
    2009 Weekly compared with daily blood glucose monitoring in women with diet-treated gestational diabetesObstetrics and Gynecology.  113:1307-1312. 2009
    2008 Diet-treated gestational diabetes mellitus: comparison of early vs routine diagnosisAmerican Journal of Obstetrics and Gynecology.  198:287.e1-287.e6. 2008
    2008 Predicting macrosomiaJournal of Ultrasound in Medicine.  27:39-43. 2008
    2007 Labor and Delivery Management for Women With DiabetesObstetrics and Gynecology Clinics of North America.  34:323-334. 2007
    2007 Perinatal significance of isolated maternal hypothyroxinemia identified in the first half of pregnancyObstetrics and Gynecology.  109:1129-1135. 2007
    2006 Long-term fetal outcomes in pregnant trauma patients 2006
    2006 Thyroid disease in pregnancyObstetrics and Gynecology.  108:1283-1292. 2006
    2006 Subclinical hypothyroidism and pregnancyObstetrical and Gynecological Survey.  61:415-420. 2006
    2006 A randomized trial of coached versus uncoached maternal pushing during the second stage of laborAmerican Journal of Obstetrics and Gynecology.  194:10-13. 2006
    2006 In reply [4]Obstetrics and Gynecology.  107:206. 2006
    2006 Subclinical hyperthyroidism and pregnancy outcomesObstetrics and Gynecology.  107:337-341. 2006
    2005 Environmental contaminants and maternal thyroid functionAmerican Journal of Obstetrics and Gynecology.  193:1889-1890. 2005
    2005 Subclinical hypothyroidism and pregnancy outcomes [5] (multiple letters)Obstetrics and Gynecology.  106:198-199. 2005
    2005 Human myometrial gene expression before and during parturitionBiology of Reproduction.  72:707-719. 2005
    2005 Subclinical hypothyroidism and pregnancy outcomesObstetrics and Gynecology.  105:239-245. 2005
    2005 Thyroid-stimulating hormone in singleton and twin pregnancy: Importance of gestational age-specific reference rangesObstetrics and Gynecology.  106:753-757. 2005
    2003 Maternal diabetes mellitus and infant malformations [3] (multiple letters)Obstetrics and Gynecology.  101:815-816. 2003
    2002 Maternal diabetes mellitus and infant malformationsObstetrics and Gynecology.  100:925-930. 2002
    2001 The continuing value of the Apgar score for the assessment of newborn infantsNew England Journal of Medicine.  344:467-471. 2001
    2001 Lack of utility of amniotic fluid index in predicting perinatal morbidity and mortality [4] (multiple letters)American Journal of Obstetrics and Gynecology.  184:778-779. 2001
    2001 Outcomes among term infants when two-hour postnatal pH is compared with pH at deliveryAmerican Journal of Obstetrics and Gynecology.  184:447-450. 2001
    2000 Ex vivo human placental transfer of trovafloxacin 2000
    2000 Predictive value of serial middle cerebral and renal artery pulsatility indices in fetuses with oligohydramnios 2000
    1999 Birth weight in relation to morbidity and mortality among newborn infantsNew England Journal of Medicine.  340:1234-1238. 1999
    1998 Pregnancy outcomes in women with gestational diabetes compared with the general obstetric population: In replyObstetrics and Gynecology.  91:239-240. 1998
    1997 Pregnancy outcomes in women with gestational diabetes compared with the general obstetric populationObstetrics and Gynecology.  90:869-873. 1997
    1997 Intraventricular Hemorrhage and Fetal Heart Rate in Very Low Birth Weight InfantsJournal of Perinatology.  17:208-212. 1997
    1997 Chorioamnionitis and endometritisInfectious Disease Clinics of North America.  11:203-222. 1997
    1996 Cholecystitis in Pregnancy 1996


    Year Title Altmetric
    2012 Hypothyroidism and Hyperthyroidism.  178-182. 2012
    2010 Hyperthyroidism and Hypothyroidism in Pregnancy.  237-242. 2010
    2010 Thyroid Disease in Pregnancy.  322-334. 2010
    2008 Maternal Hypothyroidism and Hyperthyroidism.  186-191. 2008

    Research Overview

  • -Endocrinopathies of pregnancy, including diabetes and thyroid disease
    -Labor management
    -Medical and obstetrical complications of pregnancy
  • Education And Training

  • Saint Barnabas Medical Center, Residency
  • Parkland Health and Hospital System, Postdoctoral Fellowship
  • Doctor of Medicine, Temple University 1991
  • Full Name

  • Brian Casey